  | MUWANIGWA, M. N., Modamio-Chamarro, J., ANTONY, P., Gomez-Giro, G., Krüger, R., BOLOGNIN, S., & SCHWAMBORN, J. C. (March 2024). Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease. Molecular and Cellular Neuroscience, 128, 103919. doi:10.1016/j.mcn.2024.103919  Peer Reviewed verified by ORBi |
 | Gomez Ramos, B., Ohnmacht, J., de Lange, N., VALCESCHINI, E., GINOLHAC, A., CATILLON, M., FERRANTE, D., Rakovic, A., HALDER, R., Massart, F., ARENA, G., ANTONY, P., BOLOGNIN, S., Klein, C., KRAUSE, R., Schulz, M. H., SAUTER, T., Krüger, R., & SINKKONEN, L. (19 December 2023). Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. EMBO Reports, 25 (1), 254-285. doi:10.1038/s44319-023-00024-2 Peer Reviewed verified by ORBi |
 | Mészáros, M., Phan, T., Vigh, J., Porkoláb, G., Kocsis, A., Páli, E., Polgár, T., Walter, F., BOLOGNIN, S., SCHWAMBORN, J. C., Janáky, T., Deli, M., & Veszelka, S. (2023). Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood-Brain Barrier Model and Entry to Human Brain Organoids. Cells. doi:10.3390/cells12030503 Peer Reviewed verified by ORBi |
 | Minoia, A., Dalle Carbonare, L., SCHWAMBORN, J. C., BOLOGNIN, S., & Valenti, M. (2023). Bone Tissue and the Nervous System: What Do They Have in Common? Cells. doi:10.3390/cells12010051 Peer Reviewed verified by ORBi |
BOLOGNIN, S., SMITS, L., NICKELS, S. L., MAGNI, S., ANTONY, P., GRZYB, K., KRÜGER, R., SKUPIN, A., & SCHWAMBORN, J. C. (2021). A new brain organoid model to study Parkinson’s Disease. Biomedical Science and Engineering. |
  | BOUSSAAD, I., CRUCIANI, G., BOLOGNIN, S., ANTONY, P., DORDING, C., KWON, Y.-J., Heuting, P., Fava, E., SCHWAMBORN, J. C., & KRÜGER, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3 Peer Reviewed verified by ORBi |
 | Zanetti, C., Spitz, S., Berger, E., BOLOGNIN, S., SMITS, L., Crepaz, P., Rothbauer, M., Rosser, J. M., Marchetti'Deschmann, M., SCHWAMBORN, J. C., & Ertl, P. (2021). Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson’s disease modeling and drug screening. Analyst. doi:10.1039/d0an02206c Peer Reviewed verified by ORBi |
 | JARAZO, J., BARMPA, K., Modamio, J., SARAIVA, C., SABATÉ SOLER, S., ROSETY, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., SMITS, L., Su, J., Arias-Fuenzalida, Walter, J., GOMEZ GIRO, G., Monzel, A., Qing, X., VITALI, A., CRUCIANI, G., BOUSSAAD, I., ... SCHWAMBORN, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 Peer Reviewed verified by ORBi |
 | Walter, J., BOLOGNIN, S., Poovathingal, S., MAGNI, S., GERARD, D., ANTONY, P., NICKELS, S. L., Salamanca, L., Berger, E., SMITS, L., GRZYB, K., Perfeito, R., Hoel, F., Qing, X., OHNMACHT, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... SCHWAMBORN, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864 Peer Reviewed verified by ORBi |
 | Mutti, V., Bono, F., Tomasoni, Z., Bontempi, L., Guglielmi, A., BOLOGNIN, S., SCHWAMBORN, J. C., Missale, C., & Fiorentini, C. (2021). Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway. Molecular Neurobiology. doi:10.1007/s12035-022-02748-z Peer Reviewed verified by ORBi |
 | Veszelka, S., Mészáros, M., Porkoláb, G., Szecskó, A., Kondor, N., Ferenc, G., Polgár, T. F., Katona, G., Kóta, Z., Kelemen, L., Páli, T., Vigh, J. P., Walter, F. R., BOLOGNIN, S., SCHWAMBORN, J. C., Jan, J.-S., & Deli, M. A. (2021). A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model. Pharmaceutics. doi:10.3390/pharmaceutics14010086 Peer Reviewed verified by ORBi |
 | SMITS, L., MAGNI, S., Kinugawa, K., GRZYB, K., Luginbühl, J., SABATÉ SOLER, S., BOLOGNIN, S., Shin, J., Mori, E., SKUPIN, A., & SCHWAMBORN, J. C. (2020). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. Cell and Tissue Research. doi:10.1007/s00441-020-03249-y Peer Reviewed verified by ORBi |
 | Lee, M.-H., Thomas, J., Su, Z.-L., Yeh, W.-K., Monzel, A. S., BOLOGNIN, S., SCHWAMBORN, J. C., Yang, C.-H., & Lin, H.-Y. (2020). Epitope imprinting of alpha-synuclein for sensing in Parkinson's brain organoid culture medium. Biosensors and Bioelectronics. doi:10.1016/j.bios.2020.112852 Peer Reviewed verified by ORBi |
 | Kano, M., Takanashi, M., Oyama, G., Yoritaka, A., Hatano, T., Shiba-Fukushima, K., Nagai, M., Nishiyama, K., Hasegawa, K., Inoshita, T., Ishikawa, K.-I., Akamatsu, W., Imai, Y., BOLOGNIN, S., SCHWAMBORN, J. C., & Hattori, N. (2020). Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations. NPJ Parkinson's Disease. doi:10.1038/s41531-020-00137-8 Peer Reviewed verified by ORBi |
 | Bono, F., Mutti, V., Devoto, P., BOLOGNIN, S., SCHWAMBORN, J. C., Missale, C., & Fiorentini, C. (2020). Impaired dopamine D3 and nicotinic acetylcholine receptor membrane localization in iPSCs-derived dopaminergic neurons from two Parkinson’s disease patients carrying the LRRK2 G2019S mutation. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2020.12.001 Peer Reviewed verified by ORBi |
 | MONZEL, A. S., Hemmer, K., SMITS, L., BOLOGNIN, S., Lucarelli, P., ROSETY, I., ZAGARE, A., ANTONY, P., Nickels, S., KRÜGER, R., & SCHWAMBORN, J. C. (2020). Machine learning-assisted neurotoxicity prediction in human midbrain organoids. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2020.05.011 Peer Reviewed verified by ORBi |
 | Lee, M.-H., Liu, K.-T., Thomas, J. L., Su, Z.-L., O'Hare, D., VAN WÜLLEN, T. M., MODAMIO CHAMARRO, J., BOLOGNIN, S., Luo, S.-C., SCHWAMBORN, J. C., & Lin, H.-Y. (2020). Peptide-Imprinted Poly(hydroxymethyl 3,4-ethylenedioxythiophene) Nanotubes for Detection of Alpha Synuclein in Human Brain Organoids. ACS Applied Nano Materials. doi:10.1021/acsanm.0c01476 Peer Reviewed verified by ORBi |
 | BOUSSAAD, I., Obermaier, C. D., Hanss, Z., Bobbili, D. R., BOLOGNIN, S., GLAAB, E., Wołyńska, K., Weisschuh, N., De Conti, L., May, C., Giesert, F., Grossmann, D., Lambert, A., Kirchen, S., BIRYUKOV, M., Burbulla, L. F., Massart, F., Bohler, J., Cruciani, G., ... KRÜGER, R. (2020). A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease. Science Translational Medicine, 12 (560). doi:10.1126/scitranslmed.aau3960 Peer Reviewed verified by ORBi |
 | GOMEZ GIRO, G., Arias-Fuenzalida, J., JARAZO, J., Zeuschner, D., ALI, M., Possemis, N., BOLOGNIN, S., HALDER, R., Jäger, C., Kuper, W., van Hasselt, P., Zaehres, H., DEL SOL MESA, A., van der Putten, H., Schoeler, H., & SCHWAMBORN, J. C. (2020). Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. Acta Neuropathologica Communications. doi:10.1186/s40478-019-0871-7 Peer Reviewed verified by ORBi |
Spitz, S., Zanetti, C., BOLOGNIN, S., MUWANIGWA, M. N., SMITS, L., BERGER, E., Jordan, C., Harasek, M., SCHWAMBORN, J. C., & Ertl, P. (2019). Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/43479. doi:10.1101/869701 |
SMITS, L., MAGNI, S., GRZYB, K., ANTONY, P., KRÜGER, R., SKUPIN, A., BOLOGNIN, S., & SCHWAMBORN, J. C. (2019). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/39342. doi:10.1101/589598 |
 | Walter, J., BOLOGNIN, S., ANTONY, P., NICKELS, S., Poovathhingal, S., Salamanca, L., MAGNI, S., Perfeito, R., Hoel, F., Qing, X., JARAZO, J., Arias-Fuenzalida, J., Ignac, T., MONZEL, A. S., Gonzalez-Cano, L., Pereira de Almeida, L., SKUPIN, A., Tronstad, K., & SCHWAMBORN, J. C. (2019). Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality. Stem Cell Reports. doi:10.1016/j.stemcr.2019.03.004 Peer Reviewed verified by ORBi |
 | NICKELS, S., Walter, J., BOLOGNIN, S., GERARD, D., Jäger, C., Qing, X., Tisserand, J., JARAZO, J., Hemmer, K., Harms, A., HALDER, R., Lucarelli, P., Berger, E., ANTONY, P., GLAAB, E., Hankemeier, T., Klein, C., SAUTER, T., SINKKONEN, L., & SCHWAMBORN, J. C. (2019). Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2019.09.018 Peer Reviewed verified by ORBi |
 | SMITS, L., Reinhardt, L., Reinhardt, P., Glatza, M., MONZEL, A. S., Stanslowsky, N., Rosato-Siri, M., Zanon, A., ANTONY, P., Bellmann, J., Nicklas, S., Hemmer, K., Qing, X., Berger, E., Kalmbach, N., Ehrlich, M., BOLOGNIN, S., Hicks, A., Wegner, F., ... SCHWAMBORN, J. C. (2019). Modeling Parkinson’s disease in midbrain-like organoids. NPJ Parkinson's Disease. doi:10.1038/s41531-019-0078-4 Peer Reviewed verified by ORBi |
 | BOLOGNIN, S., Fossépré, M., Qing, X., JARAZO, J., Ščančar, J., LUCUMI MORENO, E., NICKELS, S., WASNER, K., OUZREN, N., WALTER, J., GRÜNEWALD, A., GLAAB, E., Salamanca, L., Fleming, R. M. T., ANTONY, P., & SCHWAMBORN, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927 Peer Reviewed verified by ORBi |
 | Hemmer, K., SMITS, L., BOLOGNIN, S., & SCHWAMBORN, J. C. (2018). In vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading. Opera Medica et Physiologica. Peer reviewed |
 | BERGER, E., Magliaro, C., PACZIA, N., MONZEL, A. S., ANTONY, P., LINSTER, C., BOLOGNIN, S., Ahluwalia, A., & SCHWAMBORN, J. C. (2018). Millifluidic culture improves human midbrain organoid vitality and differentiation. Lab on a Chip - Miniaturisation for Chemistry and Biology. doi:10.1039/c8lc00206a Peer reviewed |
 | HEMMER, K., SMITS, L., BOLOGNIN, S., & SCHWAMBORN, J. C. (2017). In Vivo Phenotyping Of Parkinson-Specific Stem Cells Reveals Increased a-Synuclein Levels But No Spreading. bioRxiv. |
 | MONZEL, A. S., SMITS, L., HEMMER, K., HACHI, S., LUCUMI MORENO, E., VAN WÜLLEN, T. M., JARAZO, J., WALTER, J., WERTHSCHULTE, I., BOUSSAAD, I., BERGER, E., FLEMING, R. M., BOLOGNIN, S., & SCHWAMBORN, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010 Peer Reviewed verified by ORBi |
 | Palm, T., BOLOGNIN, S., MEISER, J., NICKELS, S., Traeger, C., Meilenbrock, R.-L., Brockhaus, J., Streitmueller, M., Missler, M., & SCHWAMBORN, J. C. (2015). Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Scientific Reports, 5. doi:10.1038/srep16321 Peer Reviewed verified by ORBi |
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