  | ZAGARE, A., SAUTER, T., BARMPA, K., PIRES PACHECO, M. I., KRÜGER, R., SCHWAMBORN, J. C., & SARAIVA, C. (17 April 2025). MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson's disease-associated dopaminergic neuron loss. NPJ Systems Biology and Applications, 11 (1), 37. doi:10.1038/s41540-025-00509-x  Peer Reviewed verified by ORBi |
 | Stoffels, C., Cambier, S., Subirana, M. A., Schaumlöffel, D., Gomez, G., Pittois, D., Guignard, C., SCHWAMBORN, J. C., WIRTZ, T., GUTLEB, A. C., Mercier-Bonin, M., & AUDINOT, J.-N. (05 December 2024). When subcellular chemical imaging enlightens our understanding on intestinal absorption, intracellular fate and toxicity of PFOA in vitro. Journal of Hazardous Materials, 480, 136205. doi:10.1016/j.jhazmat.2024.136205 Peer Reviewed verified by ORBi |
 | ZAGARE, A., HEMEDAN, A., ALMEIDA, C., Frangenberg, D., Gomez-Giro, G., ANTONY, P., HALDER, R., Krüger, R., GLAAB, E., OSTASZEWSKI, M., ARENA, G., & SCHWAMBORN, J. C. (2024). Insulin Resistance Is a Modifying Factor for Parkinson's Disease. Movement Disorders. doi:10.1002/mds.30039 Peer Reviewed verified by ORBi |
 | Mommaerts, K., OKAWA, S., Schmitt, M., Kofanova, O., Turner, T. R., Ben, R. N., DEL SOL MESA, A., Mathieson, W., SCHWAMBORN, J. C., Acker, J. P., & Betsou, F. (18 October 2024). Ice recrystallization inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis. Stem Cell Research, 81, 103583. doi:10.1016/j.scr.2024.103583 Peer Reviewed verified by ORBi |
  | Nguyen, H.-T., Rissanen, S.-L., Peltokangas, M., Laakkonen, T., Kettunen, J., Barthod, L., Sivakumar, R., Palojärvi, A., Junttila, P., Talvitie, J., BASSIS, M., NICKELS, S. L., Kalvala, S., Ilina, P., Tammela, P., Lehtonen, S., SCHWAMBORN, J. C., Mosser, S., & Singh, P. (October 2024). Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling. Tissue Barriers, 12 (4), 2315702. doi:10.1080/21688370.2024.2315702 Peer reviewed |
 | MUWANIGWA, M. N., Modamio-Chamarro, J., ANTONY, P., Gomez-Giro, G., Krüger, R., BOLOGNIN, S., & SCHWAMBORN, J. C. (March 2024). Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease. Molecular and Cellular Neuroscience, 128, 103919. doi:10.1016/j.mcn.2024.103919 Peer Reviewed verified by ORBi |
 | HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Merino Ruiz, C., PATRASKAKI, M., Gomez-Giro, G., Kleine Borgmann, F., Meyer, M., Carpentier, A., WARMOES, M. O., Jäger, C., MITTELBRONN, M., SCHWAMBORN, J. C., Cordero-Maldonado, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (March 2024). CLN3 deficiency leads to neurological and metabolic perturbations during early development. Life Science Alliance, 7 (3). doi:10.26508/lsa.202302057 Peer Reviewed verified by ORBi |
 | Mendonça, L. S., Henriques, D., Fernandes, V., Moreira, R., Brás, J., Duarte, S., SCHWAMBORN, J. C., & de Almeida, L. P. (08 February 2024). Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice's cerebella. Scientific Reports, 14 (1), 3236. doi:10.1038/s41598-024-53542-x Peer Reviewed verified by ORBi |
 | Sabate-Soler, S., KURNIAWAN, H., & SCHWAMBORN, J. C. (2024). Advanced brain organoids for neuroinflammation disease modeling. Neural Regeneration Research. Peer Reviewed verified by ORBi |
 | KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19 Peer Reviewed verified by ORBi |
 | ZAGARE, A., Preciat, G., NICKELS, S. L., Luo, X., MONZEL, A. S., Gomez-Giro, G., ROBERTSON, G., Jaeger, C., Sharif, J., Koseki, H., DIEDERICH, N., GLAAB, E., FLEMING, R. M., & SCHWAMBORN, J. C. (20 November 2023). Omics data integration suggests a potential idiopathic Parkinson's disease signature. Communications Biology, 6 (1), 1179. doi:10.1038/s42003-023-05548-w Peer Reviewed verified by ORBi |
 | Mavrommatis, L., Jeong, H.-W., Kindler, U., Gomez-Giro, G., Kienitz, M.-C., Stehling, M., Psathaki, O. E., Zeuschner, D., Bixel, M. G., Han, D., Morosan-Puopolo, G., Gerovska, D., Yang, J. H., Kim, J. B., Arauzo-Bravo, M. J., SCHWAMBORN, J. C., Hahn, S. A., Adams, R. H., Schöler, H. R., ... Zaehres, H. (14 November 2023). Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors. eLife, 12. doi:10.7554/elife.87081.3 Peer Reviewed verified by ORBi |
 | Mendes-Pinheiro, B., Campos, J., Marote, A., Soares-Cunha, C., NICKELS, S. L., MONZEL, A. S., Cibrão, J. R., Loureiro-Campos, E., Serra, S. C., Barata-Antunes, S., Duarte-Silva, S., Pinto, L., SCHWAMBORN, J. C., & Salgado, A. J. (02 November 2023). Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration. Cells, 12 (21), 2565. doi:10.3390/cells12212565 Peer Reviewed verified by ORBi |
 | MULICA, P., Venegas, C., LANDOULSI, Z., BADANJAK, K., DELCAMBRE, S., TZIORTZIOU, M., HEZZAZ, S., Ghelfi, J., SMAJIC, S., SCHWAMBORN, J. C., Krüger, R., ANTONY, P., MAY, P., GLAAB, E., GRÜNEWALD, A.* , & Pereira, S. L.*. (20 September 2023). Comparison of two protocols for the generation of iPSC-derived human astrocytes. Biological Procedures Online, 25 (1), 26. doi:10.1186/s12575-023-00218-x Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | SABATÉ SOLER, S., SCHWAMBORN, J. C., & Cowley, S. (27 April 2023). Means and methods for generating immunocompetent midbrain assembloid. |
 | HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Ruiz, C. M., PATRASKAKI, M., Gomez-Giro, G., Borgmann, F. K., Meyer, M., Carpentier, A., WARMOES, M. O., JÄGER, C., MITTELBRONN, M., SCHWAMBORN, J. C., CORDERO MALDONADO, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (2023). CLN3 deficiency leads to neurological and metabolic perturbations during early development. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57737. doi:10.1101/2023.03.17.533107 |
 | CHEMLA, A., ARENA, G., Onal, G., Walter, J., Berenguer-Escuder, C., Grossmann, D., GRÜNEWALD, A., SCHWAMBORN, J. C., & KRÜGER, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1. Stem Cell Research, 103145. doi:10.1016/j.scr.2023.103145 Peer reviewed |
 | CHEMLA, A., ARENA, G., SARAIVA, C., Berenguer-Escuder, C., Grossmann, D., GRÜNEWALD, A., Klein, C., Seibler, P., SCHWAMBORN, J. C., & KRÜGER, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1. Stem Cell Research, 69, 103085. doi:10.1016/j.scr.2023.103085 Peer Reviewed verified by ORBi |
 | Mészáros, M., Phan, T., Vigh, J., Porkoláb, G., Kocsis, A., Páli, E., Polgár, T., Walter, F., BOLOGNIN, S., SCHWAMBORN, J. C., Janáky, T., Deli, M., & Veszelka, S. (2023). Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood-Brain Barrier Model and Entry to Human Brain Organoids. Cells. doi:10.3390/cells12030503 Peer Reviewed verified by ORBi |
 | Smirnova, L., Caffo, B., Garcias, D., Huang, Q., Morales Pantoja, I., Tang, B., Zack, D., Berlinicke, C., Boyd, J., Harris, T., Johnson, E., Kagan, B., Kahn, J., Muotri, A., Paulhamus, B., SCHWAMBORN, J. C., Plotkin, J., Szalay, A., Vogelstein, J., ... Hartung, T. (2023). Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish. Frontiers in Science. Peer reviewed |
 | Hartung, T., Smirnova, L., Morales Pantoja, I., Akwaboah, A., Alam El Din, D., Berlinicke, C., Boyd, J., Caffo, B., Cappiello, B., Cohen-Karni, T., Curley, J., Etienne-Cummings, R., Dastgheyb, R., Gracias, D., Gilbert, F., Habela, C., Han, F., Harris, T., Herrmann, K., ... Zack, D. (2023). The Baltimore declaration toward the exploration of organoid intelligence. Frontiers in Science. Peer reviewed |
 | Minoia, A., Dalle Carbonare, L., SCHWAMBORN, J. C., BOLOGNIN, S., & Valenti, M. (2023). Bone Tissue and the Nervous System: What Do They Have in Common? Cells. doi:10.3390/cells12010051 Peer Reviewed verified by ORBi |
 | GARCIA SANTA CRUZ, B., Sölter, J., GOMEZ GIRO, G., SARAIVA, C., SABATÉ SOLER, S., Modamio Chamarro, J., BARMPA, K., SCHWAMBORN, J. C., HERTEL, F., JARAZO, J., & HUSCH, A. (2022). Generalising from conventional pipelines using deep learning in high‑throughput screening workfows. Scientific Reports. doi:10.1038/s41598-022-15623-7 Peer Reviewed verified by ORBi |
 | Danileviciute, E., Zeng, N., Capelle, C. M., Paczia, N., Gillespie, M. A., KURNIAWAN, H., Benzarti, M., Merz, M. P., COOWAR, D., Fritah, S., Vogt Weisenhorn, D. M., GOMEZ GIRO, G., GRUSDAT, M., BARON, A., Guerin, C., Franchina, D. G., Léonard, C., Domingues, O., Delhalle, S., ... HE, F. (26 May 2022). PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T(reg) homeostasis during ageing. Nature Metabolism, 4 (5), 589-607. doi:10.1038/s42255-022-00576-y Peer Reviewed verified by ORBi |
 | SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., GHELFI, J., DELCAMBRE, S., Dietrich, C., JARAZO, J., Henck, J., Balachandran, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., Pereira, S. L., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446 Peer Reviewed verified by ORBi |
 | Trezzi, J.-P., AHO, V., Jäger, C., Schade, S., Janzen, A., HICKL, O., Kunath, B., THOMAS, M., SCHMIT, K., GARCIA, P., SCIORTINO, A., Martin-Gallausiaux, C., HALDER, R., Huarte, O. U., HEURTAUX, T., Heins-Marroquin, U., Gomez-Giro, G., Weidenbach, K., DELACOUR, L., ... WILMES, P. (2022). An archaeal compound as a driver of Parkinson’s disease pathogenesis. (1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51987. doi:10.21203/rs.3.rs-1827631/v1 |
 | ZAGARE, A., BARMPA, K., SMAJIC, S., SMITS, L., GRZYB, K., GRÜNEWALD, A., SKUPIN, A., NICKELS, S. L., & SCHWAMBORN, J. C. (2022). Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression. American Journal of Human Genetics. doi:10.1016/j.ajhg.2021.12.009 Peer Reviewed verified by ORBi |
 | Cassotta, M., Geerts, H., Harbom, L., Outeiro, T. F., Pediaditakis, I., Reiner, O., Schildknecht, S., SCHWAMBORN, J. C., Bailey, J., Herrmann, K., & Hogberg, H. T. (2022). The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible. ALTEX: Alternatives to Animal Experimentation. doi:10.14573/altex.2203161 Peer Reviewed verified by ORBi |
 | SABATÉ SOLER, S., NICKELS, S. L., SARAIVA, C., Berger, E., Dubonyte, U., BARMPA, K., Lan, Y. J., Kouno, T., JARAZO, J., ROBERTSON, G., Sharif, J., Koseki, H., Thome, C., Shin, J., Cowley, S., & SCHWAMBORN, J. C. (2022). Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality. Glia. doi:10.1002/glia.24167 Peer Reviewed verified by ORBi |
 | Sabate-Soler, S., Bernini, M., & SCHWAMBORN, J. C. (2022). Immunocompetent brain organoids – Microglia enter the stage. Progress in Biomedical Engineering. doi:10.1088/2516-1091/ac8dcf Peer reviewed |
BOLOGNIN, S., SMITS, L., NICKELS, S. L., MAGNI, S., ANTONY, P., GRZYB, K., KRÜGER, R., SKUPIN, A., & SCHWAMBORN, J. C. (2021). A new brain organoid model to study Parkinson’s Disease. Biomedical Science and Engineering. |
 | NICKELS, S. L., & SCHWAMBORN, J. C. (2021). Is serine racemase (SRR) a second hit target for LRRK2-G2019S induced Parkinson’s disease? Neural Regeneration Research. doi:10.4103/1673-5374.293140 Peer Reviewed verified by ORBi |
 | Klima, S., Brüll, M., Spreng, A.-S., Suciu, I., Falt, T., SCHWAMBORN, J. C., Waldmann, T., & Leist, M. (2021). A human stem cell-derived test system for agents modifying neuronal N-methyl-d-aspartate-type glutamate receptor Ca2+-signalling. Archives of Toxicology. doi:10.1007/s00204-021-03024-0 Peer Reviewed verified by ORBi |
 | BOUSSAAD, I., CRUCIANI, G., BOLOGNIN, S., ANTONY, P., DORDING, C., KWON, Y.-J., Heuting, P., Fava, E., SCHWAMBORN, J. C., & KRÜGER, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3 Peer Reviewed verified by ORBi |
 | Zanetti, C., Spitz, S., Berger, E., BOLOGNIN, S., SMITS, L., Crepaz, P., Rothbauer, M., Rosser, J. M., Marchetti'Deschmann, M., SCHWAMBORN, J. C., & Ertl, P. (2021). Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson’s disease modeling and drug screening. Analyst. doi:10.1039/d0an02206c Peer Reviewed verified by ORBi |
 | Brown, S. J., BOUSSAAD, I., JARAZO, J., Fitzgerald, J. C., ANTONY, P., Keatinge, M., Blechman, J., SCHWAMBORN, J. C., KRÜGER, R., Placzek, M., & Bandmann, O. (2021). PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-021-84278-7 Peer Reviewed verified by ORBi |
 | ZAGARE, A., GOBIN, M., Monzel, A., & SCHWAMBORN, J. C. (2021). A robust protocol for the generation of human midbrain organoids. STAR Protocols. doi:10.1016/j.xpro.2021.100524 Peer Reviewed verified by ORBi |
 | BADANJAK, K., MULICA, P., SMAJIC, S., DELCAMBRE, S., TRANCHEVENT, L.-C., Diederich, N., Rauen, T., SCHWAMBORN, J. C., GLAAB, E., Cowley, S. A., ANTONY, P., Pereira, S. L., Venegas, C., & GRÜNEWALD, A. (2021). iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson's Disease. Frontiers in Cell and Developmental Biology, 9, 740758. doi:10.3389/fcell.2021.740758 Peer Reviewed verified by ORBi |
 | Walter, J., BOLOGNIN, S., Poovathingal, S., MAGNI, S., GERARD, D., ANTONY, P., NICKELS, S. L., Salamanca, L., Berger, E., SMITS, L., GRZYB, K., Perfeito, R., Hoel, F., Qing, X., OHNMACHT, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... SCHWAMBORN, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864 Peer Reviewed verified by ORBi |
 | Mommaerts, K., Bellora, C., Lambert, P., Tuerkmen, S., SCHWAMBORN, J. C., & BETSOU, F. (2021). Method Optimization of Skin Biopsy-Derived Fibroblast Culture for Reprogramming Into Induced Pluripotent Stem Cells. Biopreservation and Biobanking. doi:10.1089/bio.2020.0159 Peer Reviewed verified by ORBi |
 | JARAZO, J., BARMPA, K., Modamio, J., SARAIVA, C., SABATÉ SOLER, S., ROSETY, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., SMITS, L., Su, J., Arias-Fuenzalida, Walter, J., GOMEZ GIRO, G., Monzel, A., Qing, X., VITALI, A., CRUCIANI, G., BOUSSAAD, I., ... SCHWAMBORN, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 Peer Reviewed verified by ORBi |
 | Mutti, V., Bono, F., Tomasoni, Z., Bontempi, L., Guglielmi, A., BOLOGNIN, S., SCHWAMBORN, J. C., Missale, C., & Fiorentini, C. (2021). Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway. Molecular Neurobiology. doi:10.1007/s12035-022-02748-z Peer Reviewed verified by ORBi |
 | Veszelka, S., Mészáros, M., Porkoláb, G., Szecskó, A., Kondor, N., Ferenc, G., Polgár, T. F., Katona, G., Kóta, Z., Kelemen, L., Páli, T., Vigh, J. P., Walter, F. R., BOLOGNIN, S., SCHWAMBORN, J. C., Jan, J.-S., & Deli, M. A. (2021). A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model. Pharmaceutics. doi:10.3390/pharmaceutics14010086 Peer Reviewed verified by ORBi |
 | HANSS, Z., LARSEN, S., ANTONY, P., MENCKE, P., MASSART, F., JARAZO, J., SCHWAMBORN, J. C., BARBUTI, P., Mellick, G., & KRÜGER, R. (2020). Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient-Derived Neurons. Movement Disorders. doi:10.1002/mds.28365 Peer Reviewed verified by ORBi |
 | Rajan, R., Divya, K. P., Kandadai, R. M., Yadav, R., SATAGOPAM, V., Madhusoodanan, U. K., Agarwal, P., Kumar, N., Ferreira, T., Kumar, H., Sreeram Prasad, A. V., Shetty, K., Mehta, S., Desai, S., Kumar, S., Prashanth, L. K., Bhatt, M., Wadia, P., Ramalingam, S., ... Sharma, M. (18 June 2020). Genetic Architecture of Parkinson's Disease in the Indian Population: Harnessing Genetic Diversity to Address Critical Gaps in Parkinson's Disease Research. Frontiers in Neurology, 11, 524. doi:10.3389/fneur.2020.00524 Peer Reviewed verified by ORBi |
 | GOMEZ GIRO, G., Arias-Fuenzalida, J., JARAZO, J., Zeuschner, D., ALI, M., Possemis, N., BOLOGNIN, S., HALDER, R., Jäger, C., Kuper, W., van Hasselt, P., Zaehres, H., DEL SOL MESA, A., van der Putten, H., Schoeler, H., & SCHWAMBORN, J. C. (2020). Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. Acta Neuropathologica Communications. doi:10.1186/s40478-019-0871-7 Peer Reviewed verified by ORBi |
 | Lee, M.-H., Liu, K.-T., Thomas, J. L., Su, Z.-L., O'Hare, D., VAN WÜLLEN, T. M., MODAMIO CHAMARRO, J., BOLOGNIN, S., Luo, S.-C., SCHWAMBORN, J. C., & Lin, H.-Y. (2020). Peptide-Imprinted Poly(hydroxymethyl 3,4-ethylenedioxythiophene) Nanotubes for Detection of Alpha Synuclein in Human Brain Organoids. ACS Applied Nano Materials. doi:10.1021/acsanm.0c01476 Peer Reviewed verified by ORBi |
 | Kane, K., JARAZO, J., Lucumi Moreno, E., Fleming, R., & SCHWAMBORN, J. C. (2020). Passive controlled flow for Parkinson’s disease neuronal cell culture in 3D microfluidic devices. Organs-on-a-Chip. Peer reviewed |
 | Bono, F., Mutti, V., Devoto, P., BOLOGNIN, S., SCHWAMBORN, J. C., Missale, C., & Fiorentini, C. (2020). Impaired dopamine D3 and nicotinic acetylcholine receptor membrane localization in iPSCs-derived dopaminergic neurons from two Parkinson’s disease patients carrying the LRRK2 G2019S mutation. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2020.12.001 Peer Reviewed verified by ORBi |
 | SMITS, L., MAGNI, S., Kinugawa, K., GRZYB, K., Luginbühl, J., SABATÉ SOLER, S., BOLOGNIN, S., Shin, J., Mori, E., SKUPIN, A., & SCHWAMBORN, J. C. (2020). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. Cell and Tissue Research. doi:10.1007/s00441-020-03249-y Peer Reviewed verified by ORBi |
 | Lee, M.-H., Thomas, J., Su, Z.-L., Yeh, W.-K., Monzel, A. S., BOLOGNIN, S., SCHWAMBORN, J. C., Yang, C.-H., & Lin, H.-Y. (2020). Epitope imprinting of alpha-synuclein for sensing in Parkinson's brain organoid culture medium. Biosensors and Bioelectronics. doi:10.1016/j.bios.2020.112852 Peer Reviewed verified by ORBi |
 | BARBUTI, P., ANTONY, P., RODRIGUES SANTOS, B., MASSART, F., CRUCIANI, G., DORDING, C., ARIAS, J., SCHWAMBORN, J. C., & KRÜGER, R. (2020). Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson's Disease Point Mutation A30P. Cells, 9 (9). doi:10.3390/cells9092065 Peer Reviewed verified by ORBi |
 | Kano, M., Takanashi, M., Oyama, G., Yoritaka, A., Hatano, T., Shiba-Fukushima, K., Nagai, M., Nishiyama, K., Hasegawa, K., Inoshita, T., Ishikawa, K.-I., Akamatsu, W., Imai, Y., BOLOGNIN, S., SCHWAMBORN, J. C., & Hattori, N. (2020). Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations. NPJ Parkinson's Disease. doi:10.1038/s41531-020-00137-8 Peer Reviewed verified by ORBi |
 | SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., Dietrich, C., JARAZO, J., Henck, J., Balachan, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (2020). Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson’s disease. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/49376. |
 | SMITS, L., & SCHWAMBORN, J. C. (2020). Midbrain organoids: A new tool to investigate Parkinson's disease. Frontiers in Cell and Developmental Biology. doi:10.3389/fcell.2020.00359 Peer Reviewed verified by ORBi |
 | Berenguer-Escuder, C., Grossmann, D., ANTONY, P., ARENA, G., WASNER, K., MASSART, F., JARAZO, J., Walter, J., SCHWAMBORN, J. C., GRÜNEWALD, A., & KRÜGER, R. (2020). Impaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease. Human Molecular Genetics. doi:10.1093/hmg/ddaa066 Peer Reviewed verified by ORBi |
 | NICKELS, S. L., MODAMIO CHAMARRO, J., Mendes-Pinheiro, B., MONZEL, A. S., BETSOU, F., & SCHWAMBORN, J. C. (2020). Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease. Stem Cell Research. doi:10.1016/j.scr.2020.101870 Peer Reviewed verified by ORBi |
 | MONZEL, A. S., Hemmer, K., SMITS, L., BOLOGNIN, S., Lucarelli, P., ROSETY, I., ZAGARE, A., ANTONY, P., Nickels, S., KRÜGER, R., & SCHWAMBORN, J. C. (2020). Machine learning-assisted neurotoxicity prediction in human midbrain organoids. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2020.05.011 Peer Reviewed verified by ORBi |
 | BOUSSAAD, I., Obermaier, C. D., Hanss, Z., Bobbili, D. R., BOLOGNIN, S., GLAAB, E., Wołyńska, K., Weisschuh, N., De Conti, L., May, C., Giesert, F., Grossmann, D., Lambert, A., Kirchen, S., BIRYUKOV, M., Burbulla, L. F., Massart, F., Bohler, J., Cruciani, G., ... KRÜGER, R. (2020). A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease. Science Translational Medicine, 12 (560). doi:10.1126/scitranslmed.aau3960 Peer Reviewed verified by ORBi |
Spitz, S., Zanetti, C., BOLOGNIN, S., MUWANIGWA, M. N., SMITS, L., BERGER, E., Jordan, C., Harasek, M., SCHWAMBORN, J. C., & Ertl, P. (2019). Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/43479. doi:10.1101/869701 |
 | GARCIA SANTA CRUZ, B., JARAZO, J., SARAIVA, C., GOMEZ GIRO, G., MODAMIO CHAMARRO, J., SABATÉ SOLER, S., Kyriaki, B., ANTONY, P., SCHWAMBORN, J. C., HERTEL, F., & HUSCH, A. (29 November 2019). From tech to bench: Deep Learning pipeline for image segmentation of high-throughput high-content microscopy data [Poster presentation]. Advances in Computational Biology, Barcelona, Spain. |
 | GARCIA SANTA CRUZ, B., JARAZO, J., SCHWAMBORN, J. C., HERTEL, F., & HUSCH, A. (10 October 2019). Deep Learning Quality Control for High-Throughput High-Content Screening Microscopy Images [Poster presentation]. EMBO|EMBL Symposia - Seeing is Believing - Imaging the Molecular Processes of Life, Heidelberg, Germany. |
 | ARIAS, J., JARAZO, J., WALTER, J., GOMEZ GIRO, G., FORSTER, J., ANTONY, P., KRÜGER, R., & SCHWAMBORN, J. C. (2019). Automated high-throughput high-content autophagy and mitophagy analysis platform. Scientific Reports. doi:10.1038/s41598-019-45917-2 Peer Reviewed verified by ORBi |
SMITS, L., MAGNI, S., GRZYB, K., ANTONY, P., KRÜGER, R., SKUPIN, A., BOLOGNIN, S., & SCHWAMBORN, J. C. (2019). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/39342. doi:10.1101/589598 |
 | Zhu, J.-W., Zou, M.-M., Li, Y.-F., Chen, W.-J., Liu, J.-C., Chen, H., Fang, L.-P., Zhang, Y., Wang, Z.-T., Chen, J.-B., Huang, W., Li, S., Jia, W.-Q., Wang, Q.-Q., Zhen, X.-C., Liu, C.-F., Li, S., Xiao, Z.-C., Xu, G.-Q., ... Xu, R.-X. (2019). Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling. Cerebral Cortex. doi:10.1093/cercor/bhz306 Peer Reviewed verified by ORBi |
 | Kane, K., Lucumi Moreno, E., Hachi, S., Walter, M., JARAZO, J., Oliveira, M., Hankemeier, T., Vulto, P., SCHWAMBORN, J. C., Thoma, M., & Fleming, R. (2019). Automated microfluidic cell culture of stem cell derived dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-018-34828-3 Peer Reviewed verified by ORBi |
 | JARAZO, J., Qing, X., & SCHWAMBORN, J. C. (2019). Guidelines for Fluorescent Guided Biallelic HDR Targeting Selection With PiggyBac System Removal for Gene Editing. Frontiers in Genetics. doi:10.3389/fgene.2019.00190 Peer Reviewed verified by ORBi |
 | SMITS, L., Reinhardt, L., Reinhardt, P., Glatza, M., MONZEL, A. S., Stanslowsky, N., Rosato-Siri, M., Zanon, A., ANTONY, P., Bellmann, J., Nicklas, S., Hemmer, K., Qing, X., Berger, E., Kalmbach, N., Ehrlich, M., BOLOGNIN, S., Hicks, A., Wegner, F., ... SCHWAMBORN, J. C. (2019). Modeling Parkinson’s disease in midbrain-like organoids. NPJ Parkinson's Disease. doi:10.1038/s41531-019-0078-4 Peer Reviewed verified by ORBi |
 | Zhao, M., Song, K., Hao, W., Wang, L., Patil, G., Li, Q., Xu, L., Hua, F., Fu, B., SCHWAMBORN, J. C., Dorf, M., & Li, S. (2019). Non-proteolytic ubiquitination of OTULIN regulates NF-κB signaling pathway. Journal of Molecular Cell Biology. doi:10.1093/jmcb/mjz081 Peer Reviewed verified by ORBi |
 | Walter, J., BOLOGNIN, S., ANTONY, P., NICKELS, S., Poovathhingal, S., Salamanca, L., MAGNI, S., Perfeito, R., Hoel, F., Qing, X., JARAZO, J., Arias-Fuenzalida, J., Ignac, T., MONZEL, A. S., Gonzalez-Cano, L., Pereira de Almeida, L., SKUPIN, A., Tronstad, K., & SCHWAMBORN, J. C. (2019). Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality. Stem Cell Reports. doi:10.1016/j.stemcr.2019.03.004 Peer Reviewed verified by ORBi |
 | Henriques, D., Moreira, R., SCHWAMBORN, J. C., Pereira de Almeida, L., & Simoes Mendonca, L. (2019). Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation. Frontiers in Neuroscience. doi:10.3389/fnins.2019.01194 Peer Reviewed verified by ORBi |
 | NICKELS, S., Walter, J., BOLOGNIN, S., GERARD, D., Jäger, C., Qing, X., Tisserand, J., JARAZO, J., Hemmer, K., Harms, A., HALDER, R., Lucarelli, P., Berger, E., ANTONY, P., GLAAB, E., Hankemeier, T., Klein, C., SAUTER, T., SINKKONEN, L., & SCHWAMBORN, J. C. (2019). Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2019.09.018 Peer Reviewed verified by ORBi |
 | HANSS, Z., BOUSSAAD, I., JARAZO, J., SCHWAMBORN, J. C., & KRÜGER, R. (2019). Quality Control Strategy for CRISPRCas9- based Gene Editing Complicated by a Pseudogene. Frontiers in Genetics. doi:10.3389/fgene.2019.01297 Peer Reviewed verified by ORBi |
 | BOLOGNIN, S., Fossépré, M., Qing, X., JARAZO, J., Ščančar, J., LUCUMI MORENO, E., NICKELS, S., WASNER, K., OUZREN, N., WALTER, J., GRÜNEWALD, A., GLAAB, E., Salamanca, L., Fleming, R. M. T., ANTONY, P., & SCHWAMBORN, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927 Peer Reviewed verified by ORBi |
 | Hemmer, K., SMITS, L., BOLOGNIN, S., & SCHWAMBORN, J. C. (2018). In vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading. Opera Medica et Physiologica. Peer reviewed |
 | Jan, A., Jansonius, B., Delaidelli, A., Bhanshali, F., An, Y. A., Ferreira, N., SMITS, L., Negri, G. L., SCHWAMBORN, J. C., Jensen, P., Mackenzie, I., Taubert, S., & Sorensen, P. (2018). Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. Acta Neuropathologica Communications. doi:10.1186/s40478-018-0554-9 Peer Reviewed verified by ORBi |
 | Pinho, R., Paiva, I., Jerčić, K. G., Fonseca-Ornelas, L., Gerhardt, E., Fahlbusch, C., Garcia-Esparcia, P., Kerimoglu, C., PAVLOU, M. A., Villar-Piqué, A., Szegő, É., Fonseca, T. L., Odoardi, F., Soeroes, S., Rego, A. C., Fischle, W., SCHWAMBORN, J. C., Meyer, T., Kügler, S., ... Outeiro, T. F. (2018). Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein. Human Molecular Genetics. doi:10.1093/hmg/ddy326 Peer Reviewed verified by ORBi |
 | BERGER, E., Magliaro, C., PACZIA, N., MONZEL, A. S., ANTONY, P., LINSTER, C., BOLOGNIN, S., Ahluwalia, A., & SCHWAMBORN, J. C. (2018). Millifluidic culture improves human midbrain organoid vitality and differentiation. Lab on a Chip - Miniaturisation for Chemistry and Biology. doi:10.1039/c8lc00206a Peer reviewed |
 | Pamies, D., Bal-Price, A., Chesné, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U., Passier, R., SCHWAMBORN, J. C., Stacey, G., Ellinger-Ziegelbauer, H., & Daneshian, M. (2018). Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems. ALTEX: Alternativen zu Tierexperimenten. Peer Reviewed verified by ORBi |
 | Nicklas, S., Hillje, A.-L., OKAWA, S., Rudolph, I.-M., Collmann, F. M., VAN WÜLLEN, T. M., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2018). A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification. Cell Death and Differentiation. doi:10.1038/s41418-018-0144-1 Peer reviewed |
 | SCHWAMBORN, J. C. (2018). Is Parkinson’s disease a neurodevelopmental disorder and will brain organoids help us to understand it? Stem Cells and Development. doi:10.1089/scd.2017.0289 Peer Reviewed verified by ORBi |
 | WALTER, J., NICKELS, S., & SCHWAMBORN, J. C. (2017). Human induced pluripotent stem cell-derived neuronal progenitors are a suitable and effective drug discovery model for neurological mtDNA disorders. Stem Cell Investigation. doi:10.21037/sci.2017.11.08 Peer reviewed |
 | KANE, K., LUCUMI MORENO, E., HACHI, S., Walter, M., JARAZO, J., Hankemeier, T., Vulto, P., SCHWAMBORN, J. C., Thoma, M., & FLEMING, R. M. (2017). Automated micro uidic cell culture of stem cell derived dopaminergic neurons in Parkinson's disease. bioRxiv. doi:10.1038/s41598-018-34828-3 |
 | MONZEL, A. S., SMITS, L., HEMMER, K., HACHI, S., LUCUMI MORENO, E., VAN WÜLLEN, T. M., JARAZO, J., WALTER, J., WERTHSCHULTE, I., BOUSSAAD, I., BERGER, E., FLEMING, R. M., BOLOGNIN, S., & SCHWAMBORN, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010 Peer Reviewed verified by ORBi |
 | Spathis, A., Asvos, X., Ziavra, D., Karampelas, T., Topouzis, S., Cournia, Z., QING, X., Alexakos, P., SMITS, L., Dalla, C., Rideout, H., SCHWAMBORN, J. C., Tamvakopoulos, C., Fokas, D., & Vassilatis, D. (2017). Nurr1:RXRα heterodimer activation as monotherapy for Parkinson’s disease. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1616874114 Peer Reviewed verified by ORBi |
 | Gonzalez-Cano, L., Menzl, I., TISSERAND, J., NICKLAS, S., & SCHWAMBORN, J. C. (2017). Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32. Molecular Neurobiology. doi:10.1007/s12035-017-0570-y Peer Reviewed verified by ORBi |
 | HEMMER, K., SMITS, L., BOLOGNIN, S., & SCHWAMBORN, J. C. (2017). In Vivo Phenotyping Of Parkinson-Specific Stem Cells Reveals Increased a-Synuclein Levels But No Spreading. bioRxiv. |
 | ARIAS, J., JARAZO, J., QING, X., WALTER, J., GOMEZ GIRO, G., NICKELS, S., Zaehres, H., Schoeler, H. R., & SCHWAMBORN, J. C. (2017). FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling. Stem Cell Reports. doi:10.1016/j.stemcr.2017.08.026 Peer Reviewed verified by ORBi |
 | Qing, X., WALTER, J., JARAZO, J., ARIAS, J., HILLJE, A.-L., & SCHWAMBORN, J. C. (2017). CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons. Stem Cell Research. doi:10.1016/j.scr.2017.08.013 Peer reviewed |
 | Fricke, I., Viel, T., Worlitzer, M., Collmann, F., Vrachimis, A., Faust, A., Wachsmuth, L., Faber, C., Dolle, F., Kuhlmann, M., Schaefers, K., Hermann, S., SCHWAMBORN, J. C., & Jacobs, A. (2016). 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute micro- and astrogliosis in the nigrostriatal system but no Bioluminescence Imaging detectable alteration in adult neurogenesis. European Journal of Neuroscience. doi:10.1111/ejn.13232 Peer Reviewed verified by ORBi |
 | HILLJE, A.-L., & SCHWAMBORN, J. C. (2016). Utilization of stem cells to model Parkinson's disease – current state and future challenges. Future Neurology. doi:10.2217/fnl.16.7 Peer Reviewed verified by ORBi |
 | PAVLOU, M. A., COLOMBO, N., Fuertes-Alvarez, S., NICKLAS, S., GONZALEZ CANO, L., Marin, M., GONCALVES, J., & SCHWAMBORN, J. C. (2016). Expression of the Parkinson’s Disease-Associated Gene Alpha-Synuclein is Regulated by the Neuronal Cell Fate Determinant TRIM32. Molecular Neurobiology. doi:10.1007/s12035-016-9989-9 Peer Reviewed verified by ORBi |
 | Bunk, E., Ertaylan, G., Ortega, F., PAVLOU, M. A., GONZALEZ CANO, L., Stergiopoulos, A., Safaiyan, S., Voels, S., van Cann, M., Politis, P., Berninger, B., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2016). Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells. doi:10.1002/stem.2374 Peer Reviewed verified by ORBi |
 | OKAWA, S., NICKLAS, S., ZICKENROTT, S., SCHWAMBORN, J. C., & DEL SOL MESA, A. (2016). A generalized gene regulatory network model of stem cell differentiation for predicting lineage specifiers. Stem Cell Reports. doi:10.1016/j.stemcr.2016.07.014 Peer Reviewed verified by ORBi |
 | Sakalem, M. E., Seidenbecher, T., Zhang, M., Saffari, R., Kravchenko, M., Wördemann, S., Diederich, K., SCHWAMBORN, J. C., Zhang, W., & Ambrée, O. (2016). Environmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis. Hippocampus. doi:10.1002/hipo.22669 Peer Reviewed verified by ORBi |
 | Fatima, M., Kumari, R., SCHWAMBORN, J. C., Mahadevan, A., Shankar, S., Raja, R., & Seth, P. (2016). Tripartite Containing Motif 32 Modulates Proliferation of Human Neural Precursor Cells in HIV-1 Neurodegeneration. Cell Death and Differentiation. doi:10.1038/cdd.2015.138 Peer reviewed |
 | NICKLAS, S., OKAWA, S., HILLJE, A.-L., GONZALEZ CANO, L., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2015). The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs. Nucleic Acids Research. doi:10.1093/nar/gkv138 Peer Reviewed verified by ORBi |
 | Bahnassawy, L. A., Perumal, T., GONZALEZ CANO, L., HILLJE, A.-L., Taher, L., Makalowski, W., Suzuki, Y., Fuellen, G., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2015). TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability. Scientific Reports. doi:10.1038/srep13456 Peer Reviewed verified by ORBi |
 | Bishi, Wang, L., Ding, H., SCHWAMBORN, J. C., Li, S., & Dorf, M. (2015). TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase. PLoS Pathogens. Peer Reviewed verified by ORBi |
 | Palm, T., BOLOGNIN, S., MEISER, J., NICKELS, S., Traeger, C., Meilenbrock, R.-L., Brockhaus, J., Streitmueller, M., Missler, M., & SCHWAMBORN, J. C. (2015). Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Scientific Reports, 5. doi:10.1038/srep16321 Peer Reviewed verified by ORBi |
 | HILLJE, A.-L., Beckmann, E., PAVLOU, M. A., Jäger, C., PACHECO, M., SAUTER, T., SCHWAMBORN, J. C., & Lewejohann, L. (2015). The neural stem cell fate determinant TRIM32 regulates complex behavioral traits. Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2015.00075 Peer Reviewed verified by ORBi |
 | LE GRAND, J. N., GONZALEZ CANO, L., PAVLOU, M. A., & SCHWAMBORN, J. C. (2015). Neural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression. Cellular and Molecular Life Sciences. doi:10.1007/s00018-014-1774-1 Peer Reviewed verified by ORBi |
 | LUCUMI MORENO, E., HACHI, S., HEMMER, K., Trietsch, S., BAUMURATOV, A., Hankemeier, T., Vulto, P., SCHWAMBORN, J. C., & FLEMING, R. M. (2015). Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture. Lab on a Chip - Miniaturisation for Chemistry and Biology, 15, 2419-2428. doi:10.1039/C5LC00180C Peer reviewed |
 | ERTAYLAN, G., OKAWA, S., SCHWAMBORN, J. C., & DEL SOL MESA, A. (2014). Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain. Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2014.00437 Peer Reviewed verified by ORBi |
 | Worlitzer, M., & SCHWAMBORN, J. C. (2014). The Notch co-repressor protein NKAP is highly expressed in adult mouse subventricular zone neural progenitor cells. Neuroscience. doi:10.1016/j.neuroscience.2014.02.019 Peer Reviewed verified by ORBi |
 | Hargus, G., Ehrlicher, M., Arauzo-Bravo, M., HEMMER, K., Hallmann, A.-L., Reinhardt, P., Kee-Pyo, K., Adachi, K., Santourlidis, Ghanjati, F., Fauser, M., Ossig, C., Storch, Kim, J. B., SCHWAMBORN, J. C., Sterneckert, J., Schoeler, H., Kuhlmann, T., & Zaehres, H. (2014). Origin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain. Cell Reports. doi:10.1016/j.celrep.2014.08.014 Peer Reviewed verified by ORBi |
 | HEMMER, K., Zhang, M., van Wuellen, T., Sakalem, M., Tapia, N., BAUMURATOV, A., Kaltschmidt, C., Kaltschmidt, B., Schoeler, H. R., Zhang, W., & SCHWAMBORN, J. C. (2014). Induced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain. Stem Cell Reports. doi:10.1016/j.stemcr.2014.06.017 Peer Reviewed verified by ORBi |
 | Reinhardt, P., Glatza, M., Hemmer, K., Tsytsyura, Y., Thiel, C. S., Hoing, S., Moritz, S., Parga, J. A., Wagner, L., Bruder, J. M., Wu, G., Schmid, B., Ropke, A., Klingauf, J., SCHWAMBORN, J. C., Gasser, T., Scholer, H. R., & Sterneckert, J. (2013). Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE, 8 (3), 59252. doi:10.1371/journal.pone.0059252 Peer Reviewed verified by ORBi |
 | Palm, T., Hemmer, K., Winter, J., Fricke, I. B., Tarbashevich, K., Sadeghi Shakib, F., Rudolph, I.-M., Hillje, A.-L., De Luca, P., Bahnassawy, L. A., Madel, R., Viel, T., De Siervi, A., Jacobs, A. H., Diederichs, S., & SCHWAMBORN, J. C. (2013). A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop. Nucleic Acids Research, 41 (6), 3699-712. doi:10.1093/nar/gkt070 Peer Reviewed verified by ORBi |
 | Worlitzer, M. M. A., Viel, T., Jacobs, A. H., & SCHWAMBORN, J. C. (2013). The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation. European Journal of Neuroscience. doi:10.1111/ejn.12269 Peer Reviewed verified by ORBi |
 | Gonzalez-Cano, L., HILLJE, A.-L., Fuertes-Alvarez, S., Marques, M. M., Blanch, A., Ian, R. W., Irwin, M. S., SCHWAMBORN, J. C., & Marin, M. C. (2013). Regulatory feedback loop between TP73 and TRIM32. Cell Death and Disease, 4, 704. doi:10.1038/cddis.2013.224 Peer Reviewed verified by ORBi |
 | HILLJE, A.-L., PAVLOU, M. A., Beckmann, E., Worlitzer, M., Bahnassawy, L., Lewejohann, L., Palm, T., & SCHWAMBORN, J. C. (2013). TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation. Cell Death and Disease. doi:10.1038/cddis.2013.487 Peer Reviewed verified by ORBi |
 | Bahnassawy, L. A., Nicklas, S., Palm, T., Menzl, I., Birzele, F., Gillardon, F., & SCHWAMBORN, J. C. (2013). The Parkinson's Disease-Associated LRRK2 Mutation R1441G Inhibits Neuronal Differentiation of Neural Stem Cells. Stem Cells and Development. doi:10.1089/scd.2013.0163 Peer Reviewed verified by ORBi |
 | Palm, T., Bahnassawy, L. A., & SCHWAMBORN, J. C. (2012). MiRNAs and neural stem cells: a team to treat Parkinson's disease? RNA Biology, 9 (6), 720-30. doi:10.4161/rna.19984 Peer Reviewed verified by ORBi |
 | Imielski, Y., SCHWAMBORN, J. C., Luningschror, P., Heimann, P., Holzberg, M., Werner, H., Leske, O., Puschel, A. W., Memet, S., Heumann, R., Israel, A., Kaltschmidt, C., & Kaltschmidt, B. (2012). Regrowing the adult brain: NF-kappaB controls functional circuit formation and tissue homeostasis in the dentate gyrus. PLoS ONE, 7 (2), 30838. doi:10.1371/journal.pone.0030838 Peer Reviewed verified by ORBi |
 | Wiedemann, A., Hemmer, K., Bernemann, I., Gohring, G., Pogozhykh, O., Figueiredo, C., Glage, S., Schambach, A., SCHWAMBORN, J. C., Blasczyk, R., & Muller, T. (2012). Induced pluripotent stem cells generated from adult bone marrow-derived cells of the nonhuman primate (Callithrix jacchus) using a novel quad-cistronic and excisable lentiviral vector. Cellular Reprogramming, 14 (6), 485-96. doi:10.1089/cell.2012.0036 Peer Reviewed verified by ORBi |
 | Nicklas, S., Otto, A., Wu, X., Miller, P., Stelzer, S., Wen, Y., Kuang, S., Wrogemann, K., Patel, K., Ding, H., & SCHWAMBORN, J. C. (2012). TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration. PLoS ONE, 7 (1), 30445. doi:10.1371/journal.pone.0030445 Peer Reviewed verified by ORBi |
 | Kelava, I., Reillo, I., Murayama, A. Y., Kalinka, A. T., Stenzel, D., Tomancak, P., Matsuzaki, F., Lebrand, C., Sasaki, E., SCHWAMBORN, J. C., Okano, H., Huttner, W. B., & Borrell, V. (2012). Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cerebral Cortex, 22 (2), 469-81. doi:10.1093/cercor/bhr301 Peer Reviewed verified by ORBi |
 | Hoing, S., Rudhard, Y., Reinhardt, P., Glatza, M., Stehling, M., Wu, G., Peiker, C., Bocker, A., Parga, J. A., Bunk, E., SCHWAMBORN, J. C., Slack, M., Sterneckert, J., & Scholer, H. R. (2012). Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell Stem Cell, 11 (5), 620-32. doi:10.1016/j.stem.2012.07.005 Peer Reviewed verified by ORBi |
 | Han, D. W., Tapia, N., Hermann, A., Hemmer, K., Hoing, S., Arauzo-Bravo, M. J., Zaehres, H., Wu, G., Frank, S., Moritz, S., Greber, B., Yang, J. H., Lee, H. T., SCHWAMBORN, J. C., Storch, A., & Scholer, H. R. (2012). Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell, 10 (4), 465-72. doi:10.1016/j.stem.2012.02.021 Peer Reviewed verified by ORBi |
 | Worlitzer, M. M., Bunk, E. C., Hemmer, K., & SCHWAMBORN, J. C. (2012). Anti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice. Stem Cell Research and Therapy, 3 (4), 33. doi:10.1186/scrt124 Peer Reviewed verified by ORBi |
 | Stelzer, S., Worlitzer, M. M. A., Bahnassawy, L. A., Hemmer, K., Rugani, K., Werthschulte, I., Schon, A.-L., Brinkmann, B. F., Bunk, E. C., Palm, T., Ebnet, K., & SCHWAMBORN, J. C. (2012). JAM-C is an apical surface marker for neural stem cells. Stem Cells and Development, 21 (5), 757-66. doi:10.1089/scd.2011.0274 Peer Reviewed verified by ORBi |
 | Bunk, E. C., Stelzer, S., Hermann, S., Schafers, M., Schlatt, S., & SCHWAMBORN, J. C. (2011). Cellular organization of adult neurogenesis in the Common Marmoset. Aging Cell, 10 (1), 28-38. doi:10.1111/j.1474-9726.2010.00639.x Peer Reviewed verified by ORBi |
 | Khazaei, M. R., Bunk, E. C., Hillje, A.-L., Jahn, H. M., Riegler, E. M., Knoblich, J. A., Young, P., & SCHWAMBORN, J. C. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. Journal of Neurochemistry, 117 (1), 29-37. doi:10.1111/j.1471-4159.2010.06971.x Peer Reviewed verified by ORBi |
 | Hillje, A.-L., Worlitzer, M. M. A., Palm, T., & SCHWAMBORN, J. C. (2011). Neural stem cells maintain their stemness through protein kinase C zeta-mediated inhibition of TRIM32. Stem Cells, 29 (9), 1437-47. doi:10.1002/stem.687 Peer Reviewed verified by ORBi |
 | Palm, T., & SCHWAMBORN, J. C. (2010). Brain tumor stem cells. Biological Chemistry, 391 (6), 607-17. doi:10.1515/BC.2010.059 Peer reviewed |
 | Stelzer, S., Ebnet, K., & SCHWAMBORN, J. C. (2010). JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain. BMC Neuroscience, 11, 27. doi:10.1186/1471-2202-11-27 Peer Reviewed verified by ORBi |
 | SCHWAMBORN, J. C., Berezikov, E., & Knoblich, J. A. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell, 136 (5), 913-25. doi:10.1016/j.cell.2008.12.024 Peer Reviewed verified by ORBi |
 | Schlomann, U., SCHWAMBORN, J. C., Muller, M., Fassler, R., & Puschel, A. W. (2009). The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. Journal of Cell Science, 122 (Pt 12), 2034-42. doi:10.1242/jcs.038232 Peer Reviewed verified by ORBi |
 | SCHWAMBORN, J. C., & Knoblich, J. A. (2008). LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell, 2 (3), 193-4. doi:10.1016/j.stem.2008.02.010 Peer Reviewed verified by ORBi |
 | Liedtke, T., SCHWAMBORN, J. C., Schroer, U., & Thanos, S. (2007). Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2). Molecular and Cellular Proteomics, 6 (5), 895-907. doi:10.1074/mcp.M600245-MCP200 Peer reviewed |
 | SCHWAMBORN, J. C., Li, Y., & Puschel, A. W. (2006). GTPases and the control of neuronal polarity. Methods in Enzymology, 406, 715-27. doi:10.1016/S0076-6879(06)06056-3 Peer Reviewed verified by ORBi |
 | SCHWAMBORN, J. C., & Puschel, A. W. (2004). The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nature Neuroscience, 7 (9), 923-9. doi:10.1038/nn1295 Peer Reviewed verified by ORBi |
 | SCHWAMBORN, J. C., Fiore, R., Bagnard, D., Kappler, J., Kaltschmidt, C., & Puschel, A. W. (2004). Semaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells. Journal of Biological Chemistry, 279 (30), 30923-6. doi:10.1074/jbc.C400082200 Peer Reviewed verified by ORBi |
 | SCHWAMBORN, J. C., Lindecke, A., Elvers, M., Horejschi, V., Kerick, M., Rafigh, M., Pfeiffer, J., Prullage, M., Kaltschmidt, B., & Kaltschmidt, C. (2003). Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells. BMC Genomics, 4 (1), 46. doi:10.1186/1471-2164-4-46 Peer Reviewed verified by ORBi |