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![]() ![]() | MONZEL, A. S., Hemmer, K., SMITS, L., BOLOGNIN, S., Lucarelli, P., ROSETY, I., ZAGARE, A., ANTONY, P., Nickels, S., KRÜGER, R., & SCHWAMBORN, J. C. (2020). Machine learning-assisted neurotoxicity prediction in human midbrain organoids. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2020.05.011 ![]() |
![]() ![]() | SMITS, L., & SCHWAMBORN, J. C. (2020). Midbrain organoids: A new tool to investigate Parkinson's disease. Frontiers in Cell and Developmental Biology. doi:10.3389/fcell.2020.00359 ![]() |
![]() ![]() | SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., Dietrich, C., JARAZO, J., Henck, J., Balachan, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (2020). Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson’s disease. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/49376. |
Spitz, S., Zanetti, C., BOLOGNIN, S., MUWANIGWA, M. N., SMITS, L., BERGER, E., Jordan, C., Harasek, M., SCHWAMBORN, J. C., & Ertl, P. (2019). Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/43479. doi:10.1101/869701 |
![]() ![]() | GARCIA SANTA CRUZ, B., JARAZO, J., SARAIVA, C., GOMEZ GIRO, G., MODAMIO CHAMARRO, J., SABATÉ SOLER, S., Kyriaki, B., ANTONY, P., SCHWAMBORN, J. C., HERTEL, F., & HUSCH, A. (29 November 2019). From tech to bench: Deep Learning pipeline for image segmentation of high-throughput high-content microscopy data [Poster presentation]. Advances in Computational Biology, Barcelona, Spain. |
![]() ![]() | GARCIA SANTA CRUZ, B., JARAZO, J., SCHWAMBORN, J. C., HERTEL, F., & HUSCH, A. (10 October 2019). Deep Learning Quality Control for High-Throughput High-Content Screening Microscopy Images [Poster presentation]. EMBO|EMBL Symposia - Seeing is Believing - Imaging the Molecular Processes of Life, Heidelberg, Germany. |
![]() ![]() | ARIAS, J., JARAZO, J., WALTER, J., GOMEZ GIRO, G., FORSTER, J., ANTONY, P., KRÜGER, R., & SCHWAMBORN, J. C. (2019). Automated high-throughput high-content autophagy and mitophagy analysis platform. Scientific Reports. doi:10.1038/s41598-019-45917-2 ![]() |
SMITS, L., MAGNI, S., GRZYB, K., ANTONY, P., KRÜGER, R., SKUPIN, A., BOLOGNIN, S., & SCHWAMBORN, J. C. (2019). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/39342. doi:10.1101/589598 |
![]() ![]() | Henriques, D., Moreira, R., SCHWAMBORN, J. C., Pereira de Almeida, L., & Simoes Mendonca, L. (2019). Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation. Frontiers in Neuroscience. doi:10.3389/fnins.2019.01194 ![]() |
![]() ![]() | Zhao, M., Song, K., Hao, W., Wang, L., Patil, G., Li, Q., Xu, L., Hua, F., Fu, B., SCHWAMBORN, J. C., Dorf, M., & Li, S. (2019). Non-proteolytic ubiquitination of OTULIN regulates NF-κB signaling pathway. Journal of Molecular Cell Biology. doi:10.1093/jmcb/mjz081 ![]() |
![]() ![]() | Zhu, J.-W., Zou, M.-M., Li, Y.-F., Chen, W.-J., Liu, J.-C., Chen, H., Fang, L.-P., Zhang, Y., Wang, Z.-T., Chen, J.-B., Huang, W., Li, S., Jia, W.-Q., Wang, Q.-Q., Zhen, X.-C., Liu, C.-F., Li, S., Xiao, Z.-C., Xu, G.-Q., ... Xu, R.-X. (2019). Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling. Cerebral Cortex. doi:10.1093/cercor/bhz306 ![]() |
![]() ![]() | Kane, K., Lucumi Moreno, E., Hachi, S., Walter, M., JARAZO, J., Oliveira, M., Hankemeier, T., Vulto, P., SCHWAMBORN, J. C., Thoma, M., & Fleming, R. (2019). Automated microfluidic cell culture of stem cell derived dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-018-34828-3 ![]() |
![]() ![]() | JARAZO, J., Qing, X., & SCHWAMBORN, J. C. (2019). Guidelines for Fluorescent Guided Biallelic HDR Targeting Selection With PiggyBac System Removal for Gene Editing. Frontiers in Genetics. doi:10.3389/fgene.2019.00190 ![]() |
![]() ![]() | SMITS, L., Reinhardt, L., Reinhardt, P., Glatza, M., MONZEL, A. S., Stanslowsky, N., Rosato-Siri, M., Zanon, A., ANTONY, P., Bellmann, J., Nicklas, S., Hemmer, K., Qing, X., Berger, E., Kalmbach, N., Ehrlich, M., BOLOGNIN, S., Hicks, A., Wegner, F., ... SCHWAMBORN, J. C. (2019). Modeling Parkinson’s disease in midbrain-like organoids. NPJ Parkinson's Disease. doi:10.1038/s41531-019-0078-4 ![]() |
![]() ![]() | Walter, J., BOLOGNIN, S., ANTONY, P., NICKELS, S., Poovathhingal, S., Salamanca, L., MAGNI, S., Perfeito, R., Hoel, F., Qing, X., JARAZO, J., Arias-Fuenzalida, J., Ignac, T., MONZEL, A. S., Gonzalez-Cano, L., Pereira de Almeida, L., SKUPIN, A., Tronstad, K., & SCHWAMBORN, J. C. (2019). Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality. Stem Cell Reports. doi:10.1016/j.stemcr.2019.03.004 ![]() |
![]() ![]() | HANSS, Z., BOUSSAAD, I., JARAZO, J., SCHWAMBORN, J. C., & KRÜGER, R. (2019). Quality Control Strategy for CRISPRCas9- based Gene Editing Complicated by a Pseudogene. Frontiers in Genetics. doi:10.3389/fgene.2019.01297 ![]() |
![]() ![]() | NICKELS, S., Walter, J., BOLOGNIN, S., GERARD, D., Jäger, C., Qing, X., Tisserand, J., JARAZO, J., Hemmer, K., Harms, A., HALDER, R., Lucarelli, P., Berger, E., ANTONY, P., GLAAB, E., Hankemeier, T., Klein, C., SAUTER, T., SINKKONEN, L., & SCHWAMBORN, J. C. (2019). Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2019.09.018 ![]() |
![]() ![]() | BOLOGNIN, S., Fossépré, M., Qing, X., JARAZO, J., Ščančar, J., LUCUMI MORENO, E., NICKELS, S., WASNER, K., OUZREN, N., WALTER, J., GRÜNEWALD, A., GLAAB, E., Salamanca, L., Fleming, R. M. T., ANTONY, P., & SCHWAMBORN, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927 ![]() |
![]() ![]() | Pamies, D., Bal-Price, A., Chesné, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U., Passier, R., SCHWAMBORN, J. C., Stacey, G., Ellinger-Ziegelbauer, H., & Daneshian, M. (2018). Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems. ALTEX: Alternativen zu Tierexperimenten. ![]() |
![]() ![]() | Pinho, R., Paiva, I., Jerčić, K. G., Fonseca-Ornelas, L., Gerhardt, E., Fahlbusch, C., Garcia-Esparcia, P., Kerimoglu, C., PAVLOU, M. A., Villar-Piqué, A., Szegő, É., Fonseca, T. L., Odoardi, F., Soeroes, S., Rego, A. C., Fischle, W., SCHWAMBORN, J. C., Meyer, T., Kügler, S., ... Outeiro, T. F. (2018). Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein. Human Molecular Genetics. doi:10.1093/hmg/ddy326 ![]() |
![]() ![]() | Jan, A., Jansonius, B., Delaidelli, A., Bhanshali, F., An, Y. A., Ferreira, N., SMITS, L., Negri, G. L., SCHWAMBORN, J. C., Jensen, P., Mackenzie, I., Taubert, S., & Sorensen, P. (2018). Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. Acta Neuropathologica Communications. doi:10.1186/s40478-018-0554-9 ![]() |
![]() ![]() | Hemmer, K., SMITS, L., BOLOGNIN, S., & SCHWAMBORN, J. C. (2018). In vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading. Opera Medica et Physiologica. ![]() |
![]() ![]() | SCHWAMBORN, J. C. (2018). Is Parkinson’s disease a neurodevelopmental disorder and will brain organoids help us to understand it? Stem Cells and Development. doi:10.1089/scd.2017.0289 ![]() |
![]() ![]() | BERGER, E., Magliaro, C., PACZIA, N., MONZEL, A. S., ANTONY, P., LINSTER, C., BOLOGNIN, S., Ahluwalia, A., & SCHWAMBORN, J. C. (2018). Millifluidic culture improves human midbrain organoid vitality and differentiation. Lab on a Chip - Miniaturisation for Chemistry and Biology. doi:10.1039/c8lc00206a ![]() |
![]() ![]() | Nicklas, S., Hillje, A.-L., OKAWA, S., Rudolph, I.-M., Collmann, F. M., VAN WÜLLEN, T. M., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2018). A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification. Cell Death and Differentiation. doi:10.1038/s41418-018-0144-1 ![]() |
![]() ![]() | KANE, K., LUCUMI MORENO, E., HACHI, S., Walter, M., JARAZO, J., Hankemeier, T., Vulto, P., SCHWAMBORN, J. C., Thoma, M., & FLEMING, R. M. (2017). Automated micro uidic cell culture of stem cell derived dopaminergic neurons in Parkinson's disease. bioRxiv. doi:10.1038/s41598-018-34828-3 |
![]() ![]() | Gonzalez-Cano, L., Menzl, I., TISSERAND, J., NICKLAS, S., & SCHWAMBORN, J. C. (2017). Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32. Molecular Neurobiology. doi:10.1007/s12035-017-0570-y ![]() |
![]() ![]() | MONZEL, A. S., SMITS, L., HEMMER, K., HACHI, S., LUCUMI MORENO, E., VAN WÜLLEN, T. M., JARAZO, J., WALTER, J., WERTHSCHULTE, I., BOUSSAAD, I., BERGER, E., FLEMING, R. M., BOLOGNIN, S., & SCHWAMBORN, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010 ![]() |
![]() ![]() | Spathis, A., Asvos, X., Ziavra, D., Karampelas, T., Topouzis, S., Cournia, Z., QING, X., Alexakos, P., SMITS, L., Dalla, C., Rideout, H., SCHWAMBORN, J. C., Tamvakopoulos, C., Fokas, D., & Vassilatis, D. (2017). Nurr1:RXRα heterodimer activation as monotherapy for Parkinson’s disease. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1616874114 ![]() |
![]() ![]() | HEMMER, K., SMITS, L., BOLOGNIN, S., & SCHWAMBORN, J. C. (2017). In Vivo Phenotyping Of Parkinson-Specific Stem Cells Reveals Increased a-Synuclein Levels But No Spreading. bioRxiv. |
![]() ![]() | WALTER, J., NICKELS, S., & SCHWAMBORN, J. C. (2017). Human induced pluripotent stem cell-derived neuronal progenitors are a suitable and effective drug discovery model for neurological mtDNA disorders. Stem Cell Investigation. doi:10.21037/sci.2017.11.08 ![]() |
![]() ![]() | ARIAS, J., JARAZO, J., QING, X., WALTER, J., GOMEZ GIRO, G., NICKELS, S., Zaehres, H., Schoeler, H. R., & SCHWAMBORN, J. C. (2017). FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling. Stem Cell Reports. doi:10.1016/j.stemcr.2017.08.026 ![]() |
![]() ![]() | Qing, X., WALTER, J., JARAZO, J., ARIAS, J., HILLJE, A.-L., & SCHWAMBORN, J. C. (2017). CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons. Stem Cell Research. doi:10.1016/j.scr.2017.08.013 ![]() |
![]() ![]() | Fricke, I., Viel, T., Worlitzer, M., Collmann, F., Vrachimis, A., Faust, A., Wachsmuth, L., Faber, C., Dolle, F., Kuhlmann, M., Schaefers, K., Hermann, S., SCHWAMBORN, J. C., & Jacobs, A. (2016). 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute micro- and astrogliosis in the nigrostriatal system but no Bioluminescence Imaging detectable alteration in adult neurogenesis. European Journal of Neuroscience. doi:10.1111/ejn.13232 ![]() |
![]() ![]() | OKAWA, S., NICKLAS, S., ZICKENROTT, S., SCHWAMBORN, J. C., & DEL SOL MESA, A. (2016). A generalized gene regulatory network model of stem cell differentiation for predicting lineage specifiers. Stem Cell Reports. doi:10.1016/j.stemcr.2016.07.014 ![]() |
![]() ![]() | Sakalem, M. E., Seidenbecher, T., Zhang, M., Saffari, R., Kravchenko, M., Wördemann, S., Diederich, K., SCHWAMBORN, J. C., Zhang, W., & Ambrée, O. (2016). Environmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis. Hippocampus. doi:10.1002/hipo.22669 ![]() |
![]() ![]() | PAVLOU, M. A., COLOMBO, N., Fuertes-Alvarez, S., NICKLAS, S., GONZALEZ CANO, L., Marin, M., GONCALVES, J., & SCHWAMBORN, J. C. (2016). Expression of the Parkinson’s Disease-Associated Gene Alpha-Synuclein is Regulated by the Neuronal Cell Fate Determinant TRIM32. Molecular Neurobiology. doi:10.1007/s12035-016-9989-9 ![]() |
![]() ![]() | Bunk, E., Ertaylan, G., Ortega, F., PAVLOU, M. A., GONZALEZ CANO, L., Stergiopoulos, A., Safaiyan, S., Voels, S., van Cann, M., Politis, P., Berninger, B., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2016). Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells. doi:10.1002/stem.2374 ![]() |
![]() ![]() | HILLJE, A.-L., & SCHWAMBORN, J. C. (2016). Utilization of stem cells to model Parkinson's disease – current state and future challenges. Future Neurology. doi:10.2217/fnl.16.7 ![]() |
![]() ![]() | Fatima, M., Kumari, R., SCHWAMBORN, J. C., Mahadevan, A., Shankar, S., Raja, R., & Seth, P. (2016). Tripartite Containing Motif 32 Modulates Proliferation of Human Neural Precursor Cells in HIV-1 Neurodegeneration. Cell Death and Differentiation. doi:10.1038/cdd.2015.138 ![]() |
![]() ![]() | NICKLAS, S., OKAWA, S., HILLJE, A.-L., GONZALEZ CANO, L., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2015). The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs. Nucleic Acids Research. doi:10.1093/nar/gkv138 ![]() |
![]() ![]() | Bahnassawy, L. A., Perumal, T., GONZALEZ CANO, L., HILLJE, A.-L., Taher, L., Makalowski, W., Suzuki, Y., Fuellen, G., DEL SOL MESA, A., & SCHWAMBORN, J. C. (2015). TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability. Scientific Reports. doi:10.1038/srep13456 ![]() |
![]() ![]() | Bishi, Wang, L., Ding, H., SCHWAMBORN, J. C., Li, S., & Dorf, M. (2015). TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase. PLoS Pathogens. ![]() |
![]() ![]() | HILLJE, A.-L., Beckmann, E., PAVLOU, M. A., Jäger, C., PACHECO, M., SAUTER, T., SCHWAMBORN, J. C., & Lewejohann, L. (2015). The neural stem cell fate determinant TRIM32 regulates complex behavioral traits. Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2015.00075 ![]() |
![]() ![]() | Palm, T., BOLOGNIN, S., MEISER, J., NICKELS, S., Traeger, C., Meilenbrock, R.-L., Brockhaus, J., Streitmueller, M., Missler, M., & SCHWAMBORN, J. C. (2015). Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Scientific Reports, 5. doi:10.1038/srep16321 ![]() |
![]() ![]() | LE GRAND, J. N., GONZALEZ CANO, L., PAVLOU, M. A., & SCHWAMBORN, J. C. (2015). Neural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression. Cellular and Molecular Life Sciences. doi:10.1007/s00018-014-1774-1 ![]() |
![]() ![]() | LUCUMI MORENO, E., HACHI, S., HEMMER, K., Trietsch, S., BAUMURATOV, A., Hankemeier, T., Vulto, P., SCHWAMBORN, J. C., & FLEMING, R. M. (2015). Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture. Lab on a Chip - Miniaturisation for Chemistry and Biology, 15, 2419-2428. doi:10.1039/C5LC00180C ![]() |
![]() ![]() | ERTAYLAN, G., OKAWA, S., SCHWAMBORN, J. C., & DEL SOL MESA, A. (2014). Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain. Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2014.00437 ![]() |
![]() ![]() | Worlitzer, M., & SCHWAMBORN, J. C. (2014). The Notch co-repressor protein NKAP is highly expressed in adult mouse subventricular zone neural progenitor cells. Neuroscience. doi:10.1016/j.neuroscience.2014.02.019 ![]() |
![]() ![]() | Hargus, G., Ehrlicher, M., Arauzo-Bravo, M., HEMMER, K., Hallmann, A.-L., Reinhardt, P., Kee-Pyo, K., Adachi, K., Santourlidis, Ghanjati, F., Fauser, M., Ossig, C., Storch, Kim, J. B., SCHWAMBORN, J. C., Sterneckert, J., Schoeler, H., Kuhlmann, T., & Zaehres, H. (2014). Origin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain. Cell Reports. doi:10.1016/j.celrep.2014.08.014 ![]() |
![]() ![]() | HEMMER, K., Zhang, M., van Wuellen, T., Sakalem, M., Tapia, N., BAUMURATOV, A., Kaltschmidt, C., Kaltschmidt, B., Schoeler, H. R., Zhang, W., & SCHWAMBORN, J. C. (2014). Induced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain. Stem Cell Reports. doi:10.1016/j.stemcr.2014.06.017 ![]() |
![]() ![]() | Palm, T., Hemmer, K., Winter, J., Fricke, I. B., Tarbashevich, K., Sadeghi Shakib, F., Rudolph, I.-M., Hillje, A.-L., De Luca, P., Bahnassawy, L. A., Madel, R., Viel, T., De Siervi, A., Jacobs, A. H., Diederichs, S., & SCHWAMBORN, J. C. (2013). A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop. Nucleic Acids Research, 41 (6), 3699-712. doi:10.1093/nar/gkt070 ![]() |
![]() ![]() | Reinhardt, P., Glatza, M., Hemmer, K., Tsytsyura, Y., Thiel, C. S., Hoing, S., Moritz, S., Parga, J. A., Wagner, L., Bruder, J. M., Wu, G., Schmid, B., Ropke, A., Klingauf, J., SCHWAMBORN, J. C., Gasser, T., Scholer, H. R., & Sterneckert, J. (2013). Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE, 8 (3), 59252. doi:10.1371/journal.pone.0059252 ![]() |
![]() ![]() | Worlitzer, M. M. A., Viel, T., Jacobs, A. H., & SCHWAMBORN, J. C. (2013). The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation. European Journal of Neuroscience. doi:10.1111/ejn.12269 ![]() |
![]() ![]() | Bahnassawy, L. A., Nicklas, S., Palm, T., Menzl, I., Birzele, F., Gillardon, F., & SCHWAMBORN, J. C. (2013). The Parkinson's Disease-Associated LRRK2 Mutation R1441G Inhibits Neuronal Differentiation of Neural Stem Cells. Stem Cells and Development. doi:10.1089/scd.2013.0163 ![]() |
![]() ![]() | HILLJE, A.-L., PAVLOU, M. A., Beckmann, E., Worlitzer, M., Bahnassawy, L., Lewejohann, L., Palm, T., & SCHWAMBORN, J. C. (2013). TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation. Cell Death and Disease. doi:10.1038/cddis.2013.487 ![]() |
![]() ![]() | Gonzalez-Cano, L., HILLJE, A.-L., Fuertes-Alvarez, S., Marques, M. M., Blanch, A., Ian, R. W., Irwin, M. S., SCHWAMBORN, J. C., & Marin, M. C. (2013). Regulatory feedback loop between TP73 and TRIM32. Cell Death and Disease, 4, 704. doi:10.1038/cddis.2013.224 ![]() |
![]() ![]() | Palm, T., Bahnassawy, L. A., & SCHWAMBORN, J. C. (2012). MiRNAs and neural stem cells: a team to treat Parkinson's disease? RNA Biology, 9 (6), 720-30. doi:10.4161/rna.19984 ![]() |
![]() ![]() | Imielski, Y., SCHWAMBORN, J. C., Luningschror, P., Heimann, P., Holzberg, M., Werner, H., Leske, O., Puschel, A. W., Memet, S., Heumann, R., Israel, A., Kaltschmidt, C., & Kaltschmidt, B. (2012). Regrowing the adult brain: NF-kappaB controls functional circuit formation and tissue homeostasis in the dentate gyrus. PLoS ONE, 7 (2), 30838. doi:10.1371/journal.pone.0030838 ![]() |
![]() ![]() | Wiedemann, A., Hemmer, K., Bernemann, I., Gohring, G., Pogozhykh, O., Figueiredo, C., Glage, S., Schambach, A., SCHWAMBORN, J. C., Blasczyk, R., & Muller, T. (2012). Induced pluripotent stem cells generated from adult bone marrow-derived cells of the nonhuman primate (Callithrix jacchus) using a novel quad-cistronic and excisable lentiviral vector. Cellular Reprogramming, 14 (6), 485-96. doi:10.1089/cell.2012.0036 ![]() |
![]() ![]() | Nicklas, S., Otto, A., Wu, X., Miller, P., Stelzer, S., Wen, Y., Kuang, S., Wrogemann, K., Patel, K., Ding, H., & SCHWAMBORN, J. C. (2012). TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration. PLoS ONE, 7 (1), 30445. doi:10.1371/journal.pone.0030445 ![]() |
![]() ![]() | Hoing, S., Rudhard, Y., Reinhardt, P., Glatza, M., Stehling, M., Wu, G., Peiker, C., Bocker, A., Parga, J. A., Bunk, E., SCHWAMBORN, J. C., Slack, M., Sterneckert, J., & Scholer, H. R. (2012). Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell Stem Cell, 11 (5), 620-32. doi:10.1016/j.stem.2012.07.005 ![]() |
![]() ![]() | Han, D. W., Tapia, N., Hermann, A., Hemmer, K., Hoing, S., Arauzo-Bravo, M. J., Zaehres, H., Wu, G., Frank, S., Moritz, S., Greber, B., Yang, J. H., Lee, H. T., SCHWAMBORN, J. C., Storch, A., & Scholer, H. R. (2012). Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell, 10 (4), 465-72. doi:10.1016/j.stem.2012.02.021 ![]() |
![]() ![]() | Kelava, I., Reillo, I., Murayama, A. Y., Kalinka, A. T., Stenzel, D., Tomancak, P., Matsuzaki, F., Lebrand, C., Sasaki, E., SCHWAMBORN, J. C., Okano, H., Huttner, W. B., & Borrell, V. (2012). Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cerebral Cortex, 22 (2), 469-81. doi:10.1093/cercor/bhr301 ![]() |
![]() ![]() | Stelzer, S., Worlitzer, M. M. A., Bahnassawy, L. A., Hemmer, K., Rugani, K., Werthschulte, I., Schon, A.-L., Brinkmann, B. F., Bunk, E. C., Palm, T., Ebnet, K., & SCHWAMBORN, J. C. (2012). JAM-C is an apical surface marker for neural stem cells. Stem Cells and Development, 21 (5), 757-66. doi:10.1089/scd.2011.0274 ![]() |
![]() ![]() | Worlitzer, M. M., Bunk, E. C., Hemmer, K., & SCHWAMBORN, J. C. (2012). Anti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice. Stem Cell Research and Therapy, 3 (4), 33. doi:10.1186/scrt124 ![]() |
![]() ![]() | Bunk, E. C., Stelzer, S., Hermann, S., Schafers, M., Schlatt, S., & SCHWAMBORN, J. C. (2011). Cellular organization of adult neurogenesis in the Common Marmoset. Aging Cell, 10 (1), 28-38. doi:10.1111/j.1474-9726.2010.00639.x ![]() |
![]() ![]() | Khazaei, M. R., Bunk, E. C., Hillje, A.-L., Jahn, H. M., Riegler, E. M., Knoblich, J. A., Young, P., & SCHWAMBORN, J. C. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. Journal of Neurochemistry, 117 (1), 29-37. doi:10.1111/j.1471-4159.2010.06971.x ![]() |
![]() ![]() | Hillje, A.-L., Worlitzer, M. M. A., Palm, T., & SCHWAMBORN, J. C. (2011). Neural stem cells maintain their stemness through protein kinase C zeta-mediated inhibition of TRIM32. Stem Cells, 29 (9), 1437-47. doi:10.1002/stem.687 ![]() |
![]() ![]() | Stelzer, S., Ebnet, K., & SCHWAMBORN, J. C. (2010). JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain. BMC Neuroscience, 11, 27. doi:10.1186/1471-2202-11-27 ![]() |
![]() ![]() | Palm, T., & SCHWAMBORN, J. C. (2010). Brain tumor stem cells. Biological Chemistry, 391 (6), 607-17. doi:10.1515/BC.2010.059 ![]() |
![]() ![]() | SCHWAMBORN, J. C., Berezikov, E., & Knoblich, J. A. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell, 136 (5), 913-25. doi:10.1016/j.cell.2008.12.024 ![]() |
![]() ![]() | Schlomann, U., SCHWAMBORN, J. C., Muller, M., Fassler, R., & Puschel, A. W. (2009). The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. Journal of Cell Science, 122 (Pt 12), 2034-42. doi:10.1242/jcs.038232 ![]() |
![]() ![]() | SCHWAMBORN, J. C., & Knoblich, J. A. (2008). LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell, 2 (3), 193-4. doi:10.1016/j.stem.2008.02.010 ![]() |
![]() ![]() | Liedtke, T., SCHWAMBORN, J. C., Schroer, U., & Thanos, S. (2007). Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2). Molecular and Cellular Proteomics, 6 (5), 895-907. doi:10.1074/mcp.M600245-MCP200 ![]() |
![]() ![]() | SCHWAMBORN, J. C., Li, Y., & Puschel, A. W. (2006). GTPases and the control of neuronal polarity. Methods in Enzymology, 406, 715-27. doi:10.1016/S0076-6879(06)06056-3 ![]() |
![]() ![]() | SCHWAMBORN, J. C., & Puschel, A. W. (2004). The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nature Neuroscience, 7 (9), 923-9. doi:10.1038/nn1295 ![]() |
![]() ![]() | SCHWAMBORN, J. C., Fiore, R., Bagnard, D., Kappler, J., Kaltschmidt, C., & Puschel, A. W. (2004). Semaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells. Journal of Biological Chemistry, 279 (30), 30923-6. doi:10.1074/jbc.C400082200 ![]() |
![]() ![]() | SCHWAMBORN, J. C., Lindecke, A., Elvers, M., Horejschi, V., Kerick, M., Rafigh, M., Pfeiffer, J., Prullage, M., Kaltschmidt, B., & Kaltschmidt, C. (2003). Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells. BMC Genomics, 4 (1), 46. doi:10.1186/1471-2164-4-46 ![]() |