![]() ![]() | Sabate-Soler, S., Kurniawan, H., & Schwamborn, J. C. (2024). Advanced brain organoids for neuroinflammation disease modeling. Neural Regeneration Research. ![]() |
![]() ![]() | Mavrommatis, L., Jeong, H.-W., Kindler, U., Gomez-Giro, G., Kienitz, M.-C., Stehling, M., Psathaki, O. E., Zeuschner, D., Bixel, M. G., Han, D., Morosan-Puopolo, G., Gerovska, D., Yang, J. H., Kim, J. B., Arauzo-Bravo, M. J., SCHWAMBORN, J. C., Hahn, S. A., Adams, R. H., Schöler, H. R., ... Zaehres, H. (14 November 2023). Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors. eLife, 12. doi:10.7554/elife.87081.3 ![]() |
![]() ![]() | Sabaté Soler, S., Schwamborn, J. C., & Cowley, S. (27 April 2023). Means and methods for generating immunocompetent midbrain assembloid. |
![]() ![]() | HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Ruiz, C. M., PATRASKAKI, M., Gomez-Giro, G., Borgmann, F. K., Meyer, M., Carpentier, A., WARMOES, M. O., JÄGER, C., MITTELBRONN, M., SCHWAMBORN, J. C., CORDERO MALDONADO, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (2023). CLN3 deficiency leads to neurological and metabolic perturbations during early development. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57737. doi:10.1101/2023.03.17.533107 |
![]() ![]() | Smirnova, L., Caffo, B., Garcias, D., Huang, Q., Morales Pantoja, I., Tang, B., Zack, D., Berlinicke, C., Boyd, J., Harris, T., Johnson, E., Kagan, B., Kahn, J., Muotri, A., Paulhamus, B., Schwamborn, J. C., Plotkin, J., Szalay, A., Vogelstein, J., ... Hartung, T. (2023). Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish. Frontiers in Science. ![]() |
![]() ![]() | Hartung, T., Smirnova, L., Morales Pantoja, I., Akwaboah, A., Alam El Din, D., Berlinicke, C., Boyd, J., Caffo, B., Cappiello, B., Cohen-Karni, T., Curley, J., Etienne-Cummings, R., Dastgheyb, R., Gracias, D., Gilbert, F., Habela, C., Han, F., Harris, T., Herrmann, K., ... Zack, D. (2023). The Baltimore declaration toward the exploration of organoid intelligence. Frontiers in Science. ![]() |
![]() ![]() | Mészáros, M., Phan, T., Vigh, J., Porkoláb, G., Kocsis, A., Páli, E., Polgár, T., Walter, F., Bolognin, S., Schwamborn, J. C., Janáky, T., Deli, M., & Veszelka, S. (2023). Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood-Brain Barrier Model and Entry to Human Brain Organoids. Cells. doi:10.3390/cells12030503 ![]() |
![]() ![]() | Minoia, A., Dalle Carbonare, L., Schwamborn, J. C., Bolognin, S., & Valenti, M. (2023). Bone Tissue and the Nervous System: What Do They Have in Common? Cells. doi:10.3390/cells12010051 ![]() |
![]() ![]() | Chemla, A., Arena, G., Saraiva, C., Berenguer-Escuder, C., Grossmann, D., Grünewald, A., Klein, C., Seibler, P., Schwamborn, J. C., & Krüger, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1. Stem Cell Research, 69, 103085. doi:10.1016/j.scr.2023.103085 ![]() |
![]() ![]() | Chemla, A., Arena, G., Onal, G., Walter, J., Berenguer-Escuder, C., Grossmann, D., Grünewald, A., Schwamborn, J. C., & Krüger, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1. Stem Cell Research, 103145. doi:10.1016/j.scr.2023.103145 ![]() |
![]() ![]() | Garcia Santa Cruz, B., Sölter, J., Gomez Giro, G., Saraiva, C., Sabaté Soler, S., Modamio Chamarro, J., Barmpa, K., Schwamborn, J. C., Hertel, F., Jarazo, J., & Husch, A. (2022). Generalising from conventional pipelines using deep learning in high‑throughput screening workfows. Scientific Reports. doi:10.1038/s41598-022-15623-7 ![]() |
![]() ![]() | Danileviciute, E., Zeng, N., Capelle, C. M., Paczia, N., Gillespie, M. A., Kurniawan, H., Benzarti, M., Merz, M. P., Coowar, D., Fritah, S., Vogt Weisenhorn, D. M., Gomez Giro, G., Grusdat, M., Baron, A., Guerin, C., Franchina, D. G., Léonard, C., Domingues, O., Delhalle, S., ... He, F. (26 May 2022). PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T(reg) homeostasis during ageing. Nature Metabolism, 4 (5), 589-607. doi:10.1038/s42255-022-00576-y ![]() |
![]() ![]() | Smajic, S., Prada-Medina, C. A., Landoulsi, Z., Ghelfi, J., Delcambre, S., Dietrich, C., Jarazo, J., Henck, J., Balachandran, S., Pachchek, S., Morris, C. M., Antony, P., Timmermann, B., Sauer, S., Pereira, S. L., Schwamborn, J. C., May, P., Grünewald, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446 ![]() |
![]() ![]() | Zagare, A., Barmpa, K., Smajic, S., Smits, L., Grzyb, K., Grünewald, A., Skupin, A., Nickels, S. L., & Schwamborn, J. C. (2022). Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression. American Journal of Human Genetics. doi:10.1016/j.ajhg.2021.12.009 ![]() |
![]() ![]() | Cassotta, M., Geerts, H., Harbom, L., Outeiro, T. F., Pediaditakis, I., Reiner, O., Schildknecht, S., Schwamborn, J. C., Bailey, J., Herrmann, K., & Hogberg, H. T. (2022). The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible. ALTEX: Alternatives to Animal Experimentation. doi:10.14573/altex.2203161 ![]() |
![]() ![]() | Sabaté Soler, S., Nickels, S. L., Saraiva, C., Berger, E., Dubonyte, U., Barmpa, K., Lan, Y. J., Kouno, T., Jarazo, J., Robertson, G., Sharif, J., Koseki, H., Thome, C., Shin, J., Cowley, S., & Schwamborn, J. C. (2022). Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality. Glia. doi:10.1002/glia.24167 ![]() |
![]() ![]() | Trezzi, J.-P., Aho, V., Jäger, C., Schade, S., Janzen, A., Hickl, O., Kunath, B., Thomas, M., Schmit, K., Garcia, P., Sciortino, A., Martin-Gallausiaux, C., Halder, R., Huarte, O. U., Heurtaux, T., Heins-Marroquin, U., Gomez-Giro, G., Weidenbach, K., Delacour, L., ... Wilmes, P. (2022). An archaeal compound as a driver of Parkinson’s disease pathogenesis. (1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51987. doi:10.21203/rs.3.rs-1827631/v1 |
![]() ![]() | Sabate-Soler, S., Bernini, M., & Schwamborn, J. C. (2022). Immunocompetent brain organoids – Microglia enter the stage. Progress in Biomedical Engineering. doi:10.1088/2516-1091/ac8dcf ![]() |
Bolognin, S., Smits, L., Nickels, S. L., Magni, S., Antony, P., Grzyb, K., Krüger, R., Skupin, A., & Schwamborn, J. C. (2021). A new brain organoid model to study Parkinson’s Disease. Biomedical Science and Engineering. |
![]() ![]() | Mutti, V., Bono, F., Tomasoni, Z., Bontempi, L., Guglielmi, A., Bolognin, S., Schwamborn, J. C., Missale, C., & Fiorentini, C. (2021). Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway. Molecular Neurobiology. doi:10.1007/s12035-022-02748-z ![]() |
![]() ![]() | Veszelka, S., Mészáros, M., Porkoláb, G., Szecskó, A., Kondor, N., Ferenc, G., Polgár, T. F., Katona, G., Kóta, Z., Kelemen, L., Páli, T., Vigh, J. P., Walter, F. R., Bolognin, S., Schwamborn, J. C., Jan, J.-S., & Deli, M. A. (2021). A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model. Pharmaceutics. doi:10.3390/pharmaceutics14010086 ![]() |
![]() ![]() | Brown, S. J., Boussaad, I., Jarazo, J., Fitzgerald, J. C., Antony, P., Keatinge, M., Blechman, J., Schwamborn, J. C., Krüger, R., Placzek, M., & Bandmann, O. (2021). PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-021-84278-7 ![]() |
![]() ![]() | Nickels, S. L., & Schwamborn, J. C. (2021). Is serine racemase (SRR) a second hit target for LRRK2-G2019S induced Parkinson’s disease? Neural Regeneration Research. doi:10.4103/1673-5374.293140 ![]() |
![]() ![]() | Zagare, A., Gobin, M., Monzel, A., & Schwamborn, J. C. (2021). A robust protocol for the generation of human midbrain organoids. STAR Protocols. doi:10.1016/j.xpro.2021.100524 ![]() |
![]() ![]() | Klima, S., Brüll, M., Spreng, A.-S., Suciu, I., Falt, T., Schwamborn, J. C., Waldmann, T., & Leist, M. (2021). A human stem cell-derived test system for agents modifying neuronal N-methyl-d-aspartate-type glutamate receptor Ca2+-signalling. Archives of Toxicology. doi:10.1007/s00204-021-03024-0 ![]() |
![]() ![]() | Boussaad, I., Cruciani, G., Bolognin, S., Antony, P., Dording, C., Kwon, Y.-J., Heuting, P., Fava, E., Schwamborn, J. C., & Krüger, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3 ![]() |
![]() ![]() | Zanetti, C., Spitz, S., Berger, E., Bolognin, S., Smits, L., Crepaz, P., Rothbauer, M., Rosser, J. M., Marchetti'Deschmann, M., Schwamborn, J. C., & Ertl, P. (2021). Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson’s disease modeling and drug screening. Analyst. doi:10.1039/d0an02206c ![]() |
![]() ![]() | Mommaerts, K., Bellora, C., Lambert, P., Tuerkmen, S., Schwamborn, J. C., & Betsou, F. (2021). Method Optimization of Skin Biopsy-Derived Fibroblast Culture for Reprogramming Into Induced Pluripotent Stem Cells. Biopreservation and Biobanking. doi:10.1089/bio.2020.0159 ![]() |
![]() ![]() | Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L., Su, J., Arias-Fuenzalida, Walter, J., Gomez Giro, G., Monzel, A., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., ... Schwamborn, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 ![]() |
![]() ![]() | Walter, J., Bolognin, S., Poovathingal, S., Magni, S., Gerard, D., Antony, P., Nickels, S. L., Salamanca, L., Berger, E., Smits, L., Grzyb, K., Perfeito, R., Hoel, F., Qing, X., Ohnmacht, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... Schwamborn, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864 ![]() |
![]() ![]() | Badanjak, K., Mulica, P., Smajic, S., Delcambre, S., Tranchevent, L.-C., Diederich, N., Rauen, T., Schwamborn, J. C., Glaab, E., Cowley, S. A., Antony, P., Pereira, S. L., Venegas, C., & Grünewald, A. (2021). iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson's Disease. Frontiers in Cell and Developmental Biology, 9, 740758. doi:10.3389/fcell.2021.740758 ![]() |
![]() ![]() | Hanss, Z., Larsen, S., Antony, P., Mencke, P., Massart, F., Jarazo, J., Schwamborn, J. C., Barbuti, P., Mellick, G., & Krüger, R. (2020). Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient-Derived Neurons. Movement Disorders. doi:10.1002/mds.28365 ![]() |
![]() ![]() | Rajan, R., Divya, K. P., Kandadai, R. M., Yadav, R., Satagopam, V., Madhusoodanan, U. K., Agarwal, P., Kumar, N., Ferreira, T., Kumar, H., Sreeram Prasad, A. V., Shetty, K., Mehta, S., Desai, S., Kumar, S., Prashanth, L. K., Bhatt, M., Wadia, P., Ramalingam, S., ... Sharma, M. (18 June 2020). Genetic Architecture of Parkinson's Disease in the Indian Population: Harnessing Genetic Diversity to Address Critical Gaps in Parkinson's Disease Research. Frontiers in Neurology, 11, 524. doi:10.3389/fneur.2020.00524 ![]() |
![]() ![]() | Gomez Giro, G., Arias-Fuenzalida, J., Jarazo, J., Zeuschner, D., Ali, M., Possemis, N., Bolognin, S., Halder, R., Jäger, C., Kuper, W., van Hasselt, P., Zaehres, H., del Sol Mesa, A., van der Putten, H., Schoeler, H., & Schwamborn, J. C. (2020). Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. Acta Neuropathologica Communications. doi:10.1186/s40478-019-0871-7 ![]() |
![]() ![]() | Smits, L., Magni, S., Kinugawa, K., Grzyb, K., Luginbühl, J., Sabaté Soler, S., Bolognin, S., Shin, J., Mori, E., Skupin, A., & Schwamborn, J. C. (2020). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. Cell and Tissue Research. doi:10.1007/s00441-020-03249-y ![]() |
![]() ![]() | Lee, M.-H., Liu, K.-T., Thomas, J. L., Su, Z.-L., O'Hare, D., van Wüllen, T. M., Modamio Chamarro, J., Bolognin, S., Luo, S.-C., Schwamborn, J. C., & Lin, H.-Y. (2020). Peptide-Imprinted Poly(hydroxymethyl 3,4-ethylenedioxythiophene) Nanotubes for Detection of Alpha Synuclein in Human Brain Organoids. ACS Applied Nano Materials. doi:10.1021/acsanm.0c01476 ![]() |
![]() ![]() | Kane, K., Jarazo, J., Lucumi Moreno, E., Fleming, R., & Schwamborn, J. C. (2020). Passive controlled flow for Parkinson’s disease neuronal cell culture in 3D microfluidic devices. Organs-on-a-Chip. ![]() |
![]() ![]() | Barbuti, P., Antony, P., Rodrigues Santos, B., Massart, F., Cruciani, G., Dording, C., Arias, J., Schwamborn, J. C., & Krüger, R. (2020). Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson's Disease Point Mutation A30P. Cells, 9 (9). doi:10.3390/cells9092065 ![]() |
![]() ![]() | Kano, M., Takanashi, M., Oyama, G., Yoritaka, A., Hatano, T., Shiba-Fukushima, K., Nagai, M., Nishiyama, K., Hasegawa, K., Inoshita, T., Ishikawa, K.-I., Akamatsu, W., Imai, Y., Bolognin, S., Schwamborn, J. C., & Hattori, N. (2020). Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations. NPJ Parkinson's Disease. doi:10.1038/s41531-020-00137-8 ![]() |
![]() ![]() | Lee, M.-H., Thomas, J., Su, Z.-L., Yeh, W.-K., Monzel, A. S., Bolognin, S., Schwamborn, J. C., Yang, C.-H., & Lin, H.-Y. (2020). Epitope imprinting of alpha-synuclein for sensing in Parkinson's brain organoid culture medium. Biosensors and Bioelectronics. doi:10.1016/j.bios.2020.112852 ![]() |
![]() ![]() | Bono, F., Mutti, V., Devoto, P., Bolognin, S., Schwamborn, J. C., Missale, C., & Fiorentini, C. (2020). Impaired dopamine D3 and nicotinic acetylcholine receptor membrane localization in iPSCs-derived dopaminergic neurons from two Parkinson’s disease patients carrying the LRRK2 G2019S mutation. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2020.12.001 ![]() |
![]() ![]() | Smits, L., & Schwamborn, J. C. (2020). Midbrain organoids: A new tool to investigate Parkinson's disease. Frontiers in Cell and Developmental Biology. doi:10.3389/fcell.2020.00359 ![]() |
![]() ![]() | Berenguer-Escuder, C., Grossmann, D., Antony, P., Arena, G., Wasner, K., Massart, F., Jarazo, J., Walter, J., Schwamborn, J. C., Grünewald, A., & Krüger, R. (2020). Impaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease. Human Molecular Genetics. doi:10.1093/hmg/ddaa066 ![]() |
![]() ![]() | Monzel, A. S., Hemmer, K., Smits, L., Bolognin, S., Lucarelli, P., Rosety, I., Zagare, A., Antony, P., Nickels, S., Krüger, R., & Schwamborn, J. C. (2020). Machine learning-assisted neurotoxicity prediction in human midbrain organoids. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2020.05.011 ![]() |
![]() ![]() | Nickels, S. L., Modamio Chamarro, J., Mendes-Pinheiro, B., Monzel, A. S., Betsou, F., & Schwamborn, J. C. (2020). Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease. Stem Cell Research. doi:10.1016/j.scr.2020.101870 ![]() |
![]() ![]() | Smajic, S., Prada-Medina, C. A., Landoulsi, Z., Dietrich, C., Jarazo, J., Henck, J., Balachan, S., Pachchek, S., Morris, C. M., Antony, P., Timmermann, B., Sauer, S., Schwamborn, J. C., May, P., Grünewald, A., & Spielmann, M. (2020). Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson’s disease. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/49376. |
![]() ![]() | Boussaad, I., Obermaier, C. D., Hanss, Z., Bobbili, D. R., Bolognin, S., Glaab, E., Wołyńska, K., Weisschuh, N., De Conti, L., May, C., Giesert, F., Grossmann, D., Lambert, A., Kirchen, S., Biryukov, M., Burbulla, L. F., Massart, F., Bohler, J., Cruciani, G., ... Krüger, R. (2020). A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease. Science Translational Medicine, 12 (560). doi:10.1126/scitranslmed.aau3960 ![]() |
Spitz, S., Zanetti, C., Bolognin, S., Muwanigwa, M. N., Smits, L., Berger, E., Jordan, C., Harasek, M., Schwamborn, J. C., & Ertl, P. (2019). Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/43479. doi:10.1101/869701 |
![]() ![]() | Garcia Santa Cruz, B., Jarazo, J., Saraiva, C., Gomez Giro, G., Modamio Chamarro, J., Sabaté Soler, S., Kyriaki, B., Antony, P., Schwamborn, J. C., Hertel, F., & Husch, A. (29 November 2019). From tech to bench: Deep Learning pipeline for image segmentation of high-throughput high-content microscopy data [Poster presentation]. Advances in Computational Biology, Barcelona, Spain. |
![]() ![]() | Garcia Santa Cruz, B., Jarazo, J., Schwamborn, J. C., Hertel, F., & Husch, A. (10 October 2019). Deep Learning Quality Control for High-Throughput High-Content Screening Microscopy Images [Poster presentation]. EMBO|EMBL Symposia - Seeing is Believing - Imaging the Molecular Processes of Life, Heidelberg, Germany. |
![]() ![]() | Arias, J., Jarazo, J., Walter, J., Gomez Giro, G., Forster, J., Antony, P., Krüger, R., & Schwamborn, J. C. (2019). Automated high-throughput high-content autophagy and mitophagy analysis platform. Scientific Reports. doi:10.1038/s41598-019-45917-2 ![]() |
Smits, L., Magni, S., Grzyb, K., Antony, P., Krüger, R., Skupin, A., Bolognin, S., & Schwamborn, J. C. (2019). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/39342. doi:10.1101/589598 |
![]() ![]() | Smits, L., Reinhardt, L., Reinhardt, P., Glatza, M., Monzel, A. S., Stanslowsky, N., Rosato-Siri, M., Zanon, A., Antony, P., Bellmann, J., Nicklas, S., Hemmer, K., Qing, X., Berger, E., Kalmbach, N., Ehrlich, M., Bolognin, S., Hicks, A., Wegner, F., ... Schwamborn, J. C. (2019). Modeling Parkinson’s disease in midbrain-like organoids. NPJ Parkinson's Disease. doi:10.1038/s41531-019-0078-4 ![]() |
![]() ![]() | Jarazo, J., Qing, X., & Schwamborn, J. C. (2019). Guidelines for Fluorescent Guided Biallelic HDR Targeting Selection With PiggyBac System Removal for Gene Editing. Frontiers in Genetics. doi:10.3389/fgene.2019.00190 ![]() |
![]() ![]() | Kane, K., Lucumi Moreno, E., Hachi, S., Walter, M., Jarazo, J., Oliveira, M., Hankemeier, T., Vulto, P., Schwamborn, J. C., Thoma, M., & Fleming, R. (2019). Automated microfluidic cell culture of stem cell derived dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-018-34828-3 ![]() |
![]() ![]() | Nickels, S., Walter, J., Bolognin, S., Gerard, D., Jäger, C., Qing, X., Tisserand, J., Jarazo, J., Hemmer, K., Harms, A., Halder, R., Lucarelli, P., Berger, E., Antony, P., Glaab, E., Hankemeier, T., Klein, C., Sauter, T., Sinkkonen, L., & Schwamborn, J. C. (2019). Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2019.09.018 ![]() |
![]() ![]() | Zhu, J.-W., Zou, M.-M., Li, Y.-F., Chen, W.-J., Liu, J.-C., Chen, H., Fang, L.-P., Zhang, Y., Wang, Z.-T., Chen, J.-B., Huang, W., Li, S., Jia, W.-Q., Wang, Q.-Q., Zhen, X.-C., Liu, C.-F., Li, S., Xiao, Z.-C., Xu, G.-Q., ... Xu, R.-X. (2019). Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling. Cerebral Cortex. doi:10.1093/cercor/bhz306 ![]() |
![]() ![]() | Zhao, M., Song, K., Hao, W., Wang, L., Patil, G., Li, Q., Xu, L., Hua, F., Fu, B., Schwamborn, J. C., Dorf, M., & Li, S. (2019). Non-proteolytic ubiquitination of OTULIN regulates NF-κB signaling pathway. Journal of Molecular Cell Biology. doi:10.1093/jmcb/mjz081 ![]() |
![]() ![]() | Henriques, D., Moreira, R., Schwamborn, J. C., Pereira de Almeida, L., & Simoes Mendonca, L. (2019). Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation. Frontiers in Neuroscience. doi:10.3389/fnins.2019.01194 ![]() |
![]() ![]() | Walter, J., Bolognin, S., Antony, P., Nickels, S., Poovathhingal, S., Salamanca, L., Magni, S., Perfeito, R., Hoel, F., Qing, X., Jarazo, J., Arias-Fuenzalida, J., Ignac, T., Monzel, A. S., Gonzalez-Cano, L., Pereira de Almeida, L., Skupin, A., Tronstad, K., & Schwamborn, J. C. (2019). Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality. Stem Cell Reports. doi:10.1016/j.stemcr.2019.03.004 ![]() |
![]() ![]() | Hanss, Z., Boussaad, I., Jarazo, J., Schwamborn, J. C., & Krüger, R. (2019). Quality Control Strategy for CRISPRCas9- based Gene Editing Complicated by a Pseudogene. Frontiers in Genetics. doi:10.3389/fgene.2019.01297 ![]() |
![]() ![]() | Bolognin, S., Fossépré, M., Qing, X., Jarazo, J., Ščančar, J., Lucumi Moreno, E., Nickels, S., Wasner, K., Ouzren, N., Walter, J., Grünewald, A., Glaab, E., Salamanca, L., Fleming, R. M. T., Antony, P., & Schwamborn, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927 ![]() |
![]() ![]() | Pamies, D., Bal-Price, A., Chesné, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U., Passier, R., Schwamborn, J. C., Stacey, G., Ellinger-Ziegelbauer, H., & Daneshian, M. (2018). Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems. ALTEX: Alternativen zu Tierexperimenten. ![]() |
![]() ![]() | Jan, A., Jansonius, B., Delaidelli, A., Bhanshali, F., An, Y. A., Ferreira, N., Smits, L., Negri, G. L., Schwamborn, J. C., Jensen, P., Mackenzie, I., Taubert, S., & Sorensen, P. (2018). Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. Acta Neuropathologica Communications. doi:10.1186/s40478-018-0554-9 ![]() |
![]() ![]() | Hemmer, K., Smits, L., Bolognin, S., & Schwamborn, J. C. (2018). In vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading. Opera Medica et Physiologica. ![]() |
![]() ![]() | Berger, E., Magliaro, C., Paczia, N., Monzel, A. S., Antony, P., Linster, C., Bolognin, S., Ahluwalia, A., & Schwamborn, J. C. (2018). Millifluidic culture improves human midbrain organoid vitality and differentiation. Lab on a Chip - Miniaturisation for Chemistry and Biology. doi:10.1039/c8lc00206a ![]() |
![]() ![]() | Pinho, R., Paiva, I., Jerčić, K. G., Fonseca-Ornelas, L., Gerhardt, E., Fahlbusch, C., Garcia-Esparcia, P., Kerimoglu, C., Pavlou, M. A., Villar-Piqué, A., Szegő, É., Fonseca, T. L., Odoardi, F., Soeroes, S., Rego, A. C., Fischle, W., Schwamborn, J. C., Meyer, T., Kügler, S., ... Outeiro, T. F. (2018). Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein. Human Molecular Genetics. doi:10.1093/hmg/ddy326 ![]() |
![]() ![]() | Nicklas, S., Hillje, A.-L., Okawa, S., Rudolph, I.-M., Collmann, F. M., Van Wüllen, T. M., del Sol Mesa, A., & Schwamborn, J. C. (2018). A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification. Cell Death and Differentiation. doi:10.1038/s41418-018-0144-1 ![]() |
![]() ![]() | Schwamborn, J. C. (2018). Is Parkinson’s disease a neurodevelopmental disorder and will brain organoids help us to understand it? Stem Cells and Development. doi:10.1089/scd.2017.0289 ![]() |
![]() ![]() | Hemmer, K., Smits, L., Bolognin, S., & Schwamborn, J. C. (2017). In Vivo Phenotyping Of Parkinson-Specific Stem Cells Reveals Increased a-Synuclein Levels But No Spreading. bioRxiv. |
![]() ![]() | Gonzalez-Cano, L., Menzl, I., Tisserand, J., Nicklas, S., & Schwamborn, J. C. (2017). Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32. Molecular Neurobiology. doi:10.1007/s12035-017-0570-y ![]() |
![]() ![]() | Kane, K., Lucumi Moreno, E., Hachi, S., Walter, M., Jarazo, J., Hankemeier, T., Vulto, P., Schwamborn, J. C., Thoma, M., & Fleming, R. M. (2017). Automated micro uidic cell culture of stem cell derived dopaminergic neurons in Parkinson's disease. bioRxiv. doi:10.1038/s41598-018-34828-3 |
![]() ![]() | Spathis, A., Asvos, X., Ziavra, D., Karampelas, T., Topouzis, S., Cournia, Z., Qing, X., Alexakos, P., Smits, L., Dalla, C., Rideout, H., Schwamborn, J. C., Tamvakopoulos, C., Fokas, D., & Vassilatis, D. (2017). Nurr1:RXRα heterodimer activation as monotherapy for Parkinson’s disease. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1616874114 ![]() |
![]() ![]() | Monzel, A. S., Smits, L., Hemmer, K., Hachi, S., Lucumi Moreno, E., Van Wüllen, T. M., Jarazo, J., Walter, J., Werthschulte, I., Boussaad, I., Berger, E., Fleming, R. M., Bolognin, S., & Schwamborn, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010 ![]() |
![]() ![]() | Walter, J., Nickels, S., & Schwamborn, J. C. (2017). Human induced pluripotent stem cell-derived neuronal progenitors are a suitable and effective drug discovery model for neurological mtDNA disorders. Stem Cell Investigation. doi:10.21037/sci.2017.11.08 ![]() |
![]() ![]() | Arias, J., Jarazo, J., Qing, X., Walter, J., Gomez Giro, G., Nickels, S., Zaehres, H., Schoeler, H. R., & Schwamborn, J. C. (2017). FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling. Stem Cell Reports. doi:10.1016/j.stemcr.2017.08.026 ![]() |
![]() ![]() | Qing, X., Walter, J., Jarazo, J., Arias, J., Hillje, A.-L., & Schwamborn, J. C. (2017). CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons. Stem Cell Research. doi:10.1016/j.scr.2017.08.013 ![]() |
![]() ![]() | Fricke, I., Viel, T., Worlitzer, M., Collmann, F., Vrachimis, A., Faust, A., Wachsmuth, L., Faber, C., Dolle, F., Kuhlmann, M., Schaefers, K., Hermann, S., Schwamborn, J. C., & Jacobs, A. (2016). 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute micro- and astrogliosis in the nigrostriatal system but no Bioluminescence Imaging detectable alteration in adult neurogenesis. European Journal of Neuroscience. doi:10.1111/ejn.13232 ![]() |
![]() ![]() | Pavlou, M. A., Colombo, N., Fuertes-Alvarez, S., Nicklas, S., Gonzalez Cano, L., Marin, M., Goncalves, J., & Schwamborn, J. C. (2016). Expression of the Parkinson’s Disease-Associated Gene Alpha-Synuclein is Regulated by the Neuronal Cell Fate Determinant TRIM32. Molecular Neurobiology. doi:10.1007/s12035-016-9989-9 ![]() |
![]() ![]() | Bunk, E., Ertaylan, G., Ortega, F., Pavlou, M. A., Gonzalez Cano, L., Stergiopoulos, A., Safaiyan, S., Voels, S., van Cann, M., Politis, P., Berninger, B., del Sol Mesa, A., & Schwamborn, J. C. (2016). Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells. doi:10.1002/stem.2374 ![]() |
![]() ![]() | Hillje, A.-L., & Schwamborn, J. C. (2016). Utilization of stem cells to model Parkinson's disease – current state and future challenges. Future Neurology. doi:10.2217/fnl.16.7 ![]() |
![]() ![]() | Okawa, S., Nicklas, S., Zickenrott, S., Schwamborn, J. C., & del Sol Mesa, A. (2016). A generalized gene regulatory network model of stem cell differentiation for predicting lineage specifiers. Stem Cell Reports. doi:10.1016/j.stemcr.2016.07.014 ![]() |
![]() ![]() | Sakalem, M. E., Seidenbecher, T., Zhang, M., Saffari, R., Kravchenko, M., Wördemann, S., Diederich, K., Schwamborn, J. C., Zhang, W., & Ambrée, O. (2016). Environmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis. Hippocampus. doi:10.1002/hipo.22669 ![]() |
![]() ![]() | Fatima, M., Kumari, R., Schwamborn, J. C., Mahadevan, A., Shankar, S., Raja, R., & Seth, P. (2016). Tripartite Containing Motif 32 Modulates Proliferation of Human Neural Precursor Cells in HIV-1 Neurodegeneration. Cell Death and Differentiation. doi:10.1038/cdd.2015.138 ![]() |
![]() ![]() | Nicklas, S., Okawa, S., Hillje, A.-L., Gonzalez Cano, L., del Sol Mesa, A., & Schwamborn, J. C. (2015). The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs. Nucleic Acids Research. doi:10.1093/nar/gkv138 ![]() |
![]() ![]() | Bahnassawy, L. A., Perumal, T., Gonzalez Cano, L., Hillje, A.-L., Taher, L., Makalowski, W., Suzuki, Y., Fuellen, G., del Sol Mesa, A., & Schwamborn, J. C. (2015). TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability. Scientific Reports. doi:10.1038/srep13456 ![]() |
![]() ![]() | Bishi, Wang, L., Ding, H., Schwamborn, J. C., Li, S., & Dorf, M. (2015). TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase. PLoS Pathogens. ![]() |
![]() ![]() | Hillje, A.-L., Beckmann, E., Pavlou, M. A., Jäger, C., Pacheco, M., Sauter, T., Schwamborn, J. C., & Lewejohann, L. (2015). The neural stem cell fate determinant TRIM32 regulates complex behavioral traits. Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2015.00075 ![]() |
![]() ![]() | Palm, T., Bolognin, S., Meiser, J., Nickels, S., Traeger, C., Meilenbrock, R.-L., Brockhaus, J., Streitmueller, M., Missler, M., & Schwamborn, J. C. (2015). Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Scientific Reports, 5. doi:10.1038/srep16321 ![]() |
![]() ![]() | Le Grand, J. N., Gonzalez Cano, L., Pavlou, M. A., & Schwamborn, J. C. (2015). Neural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression. Cellular and Molecular Life Sciences. doi:10.1007/s00018-014-1774-1 ![]() |
![]() ![]() | Lucumi Moreno, E., Hachi, S., Hemmer, K., Trietsch, S., Baumuratov, A., Hankemeier, T., Vulto, P., Schwamborn, J. C., & Fleming, R. M. (2015). Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture. Lab on a Chip - Miniaturisation for Chemistry and Biology, 15, 2419-2428. doi:10.1039/C5LC00180C ![]() |
![]() ![]() | Ertaylan, G., Okawa, S., Schwamborn, J. C., & del Sol Mesa, A. (2014). Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain. Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2014.00437 ![]() |
![]() ![]() | Hargus, G., Ehrlicher, M., Arauzo-Bravo, M., Hemmer, K., Hallmann, A.-L., Reinhardt, P., Kee-Pyo, K., Adachi, K., Santourlidis, Ghanjati, F., Fauser, M., Ossig, C., Storch, Kim, J. B., Schwamborn, J. C., Sterneckert, J., Schoeler, H., Kuhlmann, T., & Zaehres, H. (2014). Origin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain. Cell Reports. doi:10.1016/j.celrep.2014.08.014 ![]() |
![]() ![]() | Worlitzer, M., & Schwamborn, J. C. (2014). The Notch co-repressor protein NKAP is highly expressed in adult mouse subventricular zone neural progenitor cells. Neuroscience. doi:10.1016/j.neuroscience.2014.02.019 ![]() |
![]() ![]() | Hemmer, K., Zhang, M., van Wuellen, T., Sakalem, M., Tapia, N., Baumuratov, A., Kaltschmidt, C., Kaltschmidt, B., Schoeler, H. R., Zhang, W., & Schwamborn, J. C. (2014). Induced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain. Stem Cell Reports. doi:10.1016/j.stemcr.2014.06.017 ![]() |
![]() ![]() | Reinhardt, P., Glatza, M., Hemmer, K., Tsytsyura, Y., Thiel, C. S., Hoing, S., Moritz, S., Parga, J. A., Wagner, L., Bruder, J. M., Wu, G., Schmid, B., Ropke, A., Klingauf, J., Schwamborn, J. C., Gasser, T., Scholer, H. R., & Sterneckert, J. (2013). Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE, 8 (3), 59252. doi:10.1371/journal.pone.0059252 ![]() |
![]() ![]() | Palm, T., Hemmer, K., Winter, J., Fricke, I. B., Tarbashevich, K., Sadeghi Shakib, F., Rudolph, I.-M., Hillje, A.-L., De Luca, P., Bahnassawy, L. A., Madel, R., Viel, T., De Siervi, A., Jacobs, A. H., Diederichs, S., & Schwamborn, J. C. (2013). A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop. Nucleic Acids Research, 41 (6), 3699-712. doi:10.1093/nar/gkt070 ![]() |
![]() ![]() | Worlitzer, M. M. A., Viel, T., Jacobs, A. H., & Schwamborn, J. C. (2013). The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation. European Journal of Neuroscience. doi:10.1111/ejn.12269 ![]() |
![]() ![]() | Gonzalez-Cano, L., Hillje, A.-L., Fuertes-Alvarez, S., Marques, M. M., Blanch, A., Ian, R. W., Irwin, M. S., Schwamborn, J. C., & Marin, M. C. (2013). Regulatory feedback loop between TP73 and TRIM32. Cell Death and Disease, 4, 704. doi:10.1038/cddis.2013.224 ![]() |
![]() ![]() | Hillje, A.-L., Pavlou, M. A., Beckmann, E., Worlitzer, M., Bahnassawy, L., Lewejohann, L., Palm, T., & Schwamborn, J. C. (2013). TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation. Cell Death and Disease. doi:10.1038/cddis.2013.487 ![]() |
![]() ![]() | Bahnassawy, L. A., Nicklas, S., Palm, T., Menzl, I., Birzele, F., Gillardon, F., & Schwamborn, J. C. (2013). The Parkinson's Disease-Associated LRRK2 Mutation R1441G Inhibits Neuronal Differentiation of Neural Stem Cells. Stem Cells and Development. doi:10.1089/scd.2013.0163 ![]() |
![]() ![]() | Imielski, Y., Schwamborn, J. C., Luningschror, P., Heimann, P., Holzberg, M., Werner, H., Leske, O., Puschel, A. W., Memet, S., Heumann, R., Israel, A., Kaltschmidt, C., & Kaltschmidt, B. (2012). Regrowing the adult brain: NF-kappaB controls functional circuit formation and tissue homeostasis in the dentate gyrus. PLoS ONE, 7 (2), 30838. doi:10.1371/journal.pone.0030838 ![]() |
![]() ![]() | Palm, T., Bahnassawy, L. A., & Schwamborn, J. C. (2012). MiRNAs and neural stem cells: a team to treat Parkinson's disease? RNA Biology, 9 (6), 720-30. doi:10.4161/rna.19984 ![]() |
![]() ![]() | Wiedemann, A., Hemmer, K., Bernemann, I., Gohring, G., Pogozhykh, O., Figueiredo, C., Glage, S., Schambach, A., Schwamborn, J. C., Blasczyk, R., & Muller, T. (2012). Induced pluripotent stem cells generated from adult bone marrow-derived cells of the nonhuman primate (Callithrix jacchus) using a novel quad-cistronic and excisable lentiviral vector. Cellular Reprogramming, 14 (6), 485-96. doi:10.1089/cell.2012.0036 ![]() |
![]() ![]() | Nicklas, S., Otto, A., Wu, X., Miller, P., Stelzer, S., Wen, Y., Kuang, S., Wrogemann, K., Patel, K., Ding, H., & Schwamborn, J. C. (2012). TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration. PLoS ONE, 7 (1), 30445. doi:10.1371/journal.pone.0030445 ![]() |
![]() ![]() | Kelava, I., Reillo, I., Murayama, A. Y., Kalinka, A. T., Stenzel, D., Tomancak, P., Matsuzaki, F., Lebrand, C., Sasaki, E., Schwamborn, J. C., Okano, H., Huttner, W. B., & Borrell, V. (2012). Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cerebral Cortex, 22 (2), 469-81. doi:10.1093/cercor/bhr301 ![]() |
![]() ![]() | Hoing, S., Rudhard, Y., Reinhardt, P., Glatza, M., Stehling, M., Wu, G., Peiker, C., Bocker, A., Parga, J. A., Bunk, E., Schwamborn, J. C., Slack, M., Sterneckert, J., & Scholer, H. R. (2012). Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell Stem Cell, 11 (5), 620-32. doi:10.1016/j.stem.2012.07.005 ![]() |
![]() ![]() | Han, D. W., Tapia, N., Hermann, A., Hemmer, K., Hoing, S., Arauzo-Bravo, M. J., Zaehres, H., Wu, G., Frank, S., Moritz, S., Greber, B., Yang, J. H., Lee, H. T., Schwamborn, J. C., Storch, A., & Scholer, H. R. (2012). Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell, 10 (4), 465-72. doi:10.1016/j.stem.2012.02.021 ![]() |
![]() ![]() | Worlitzer, M. M., Bunk, E. C., Hemmer, K., & Schwamborn, J. C. (2012). Anti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice. Stem Cell Research and Therapy, 3 (4), 33. doi:10.1186/scrt124 ![]() |
![]() ![]() | Stelzer, S., Worlitzer, M. M. A., Bahnassawy, L. A., Hemmer, K., Rugani, K., Werthschulte, I., Schon, A.-L., Brinkmann, B. F., Bunk, E. C., Palm, T., Ebnet, K., & Schwamborn, J. C. (2012). JAM-C is an apical surface marker for neural stem cells. Stem Cells and Development, 21 (5), 757-66. doi:10.1089/scd.2011.0274 ![]() |
![]() ![]() | Bunk, E. C., Stelzer, S., Hermann, S., Schafers, M., Schlatt, S., & Schwamborn, J. C. (2011). Cellular organization of adult neurogenesis in the Common Marmoset. Aging Cell, 10 (1), 28-38. doi:10.1111/j.1474-9726.2010.00639.x ![]() |
![]() ![]() | Khazaei, M. R., Bunk, E. C., Hillje, A.-L., Jahn, H. M., Riegler, E. M., Knoblich, J. A., Young, P., & Schwamborn, J. C. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. Journal of Neurochemistry, 117 (1), 29-37. doi:10.1111/j.1471-4159.2010.06971.x ![]() |
![]() ![]() | Hillje, A.-L., Worlitzer, M. M. A., Palm, T., & Schwamborn, J. C. (2011). Neural stem cells maintain their stemness through protein kinase C zeta-mediated inhibition of TRIM32. Stem Cells, 29 (9), 1437-47. doi:10.1002/stem.687 ![]() |
![]() ![]() | Palm, T., & Schwamborn, J. C. (2010). Brain tumor stem cells. Biological Chemistry, 391 (6), 607-17. doi:10.1515/BC.2010.059 ![]() |
![]() ![]() | Stelzer, S., Ebnet, K., & Schwamborn, J. C. (2010). JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain. BMC Neuroscience, 11, 27. doi:10.1186/1471-2202-11-27 ![]() |
![]() ![]() | Schwamborn, J. C., Berezikov, E., & Knoblich, J. A. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell, 136 (5), 913-25. doi:10.1016/j.cell.2008.12.024 ![]() |
![]() ![]() | Schlomann, U., Schwamborn, J. C., Muller, M., Fassler, R., & Puschel, A. W. (2009). The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. Journal of Cell Science, 122 (Pt 12), 2034-42. doi:10.1242/jcs.038232 ![]() |
![]() ![]() | Schwamborn, J. C., & Knoblich, J. A. (2008). LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell, 2 (3), 193-4. doi:10.1016/j.stem.2008.02.010 ![]() |
![]() ![]() | Liedtke, T., Schwamborn, J. C., Schroer, U., & Thanos, S. (2007). Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2). Molecular and Cellular Proteomics, 6 (5), 895-907. doi:10.1074/mcp.M600245-MCP200 ![]() |
![]() ![]() | Schwamborn, J. C., Li, Y., & Puschel, A. W. (2006). GTPases and the control of neuronal polarity. Methods in Enzymology, 406, 715-27. doi:10.1016/S0076-6879(06)06056-3 ![]() |
![]() ![]() | Schwamborn, J. C., & Puschel, A. W. (2004). The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nature Neuroscience, 7 (9), 923-9. doi:10.1038/nn1295 ![]() |
![]() ![]() | Schwamborn, J. C., Fiore, R., Bagnard, D., Kappler, J., Kaltschmidt, C., & Puschel, A. W. (2004). Semaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells. Journal of Biological Chemistry, 279 (30), 30923-6. doi:10.1074/jbc.C400082200 ![]() |
![]() ![]() | Schwamborn, J. C., Lindecke, A., Elvers, M., Horejschi, V., Kerick, M., Rafigh, M., Pfeiffer, J., Prullage, M., Kaltschmidt, B., & Kaltschmidt, C. (2003). Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells. BMC Genomics, 4 (1), 46. doi:10.1186/1471-2164-4-46 ![]() |