  | PACHCHEK, S.* , LANDOULSI, Z.* , PAVELKA, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Reddy Bobbili, D., Casadei, N., MAY, P.* , KRÜGER, R.* , & NCER-PD Consortium. (23 November 2023). Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson's study. NPJ Parkinson's Disease, 9 (1), 156. doi:10.1038/s41531-023-00595-w  Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | HANFF, A.-M., PAULY, C., PAULY, L., RAUSCHENBERGER, A., LEIST, A., KRÜGER, R., Zeegers, M. P.* , McCrum, C.* , & NCER-PD consortium. (23 November 2023). Determinants of patient-reported functional mobility in people with Parkinson's disease: A systematic review. Gait and Posture, 108, 97 - 109. doi:10.1016/j.gaitpost.2023.11.013 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | HANFF, A.-M., McCrum, C., RAUSCHENBERGER, A., Aguayo, G., PAULY, C., JONSDOTTIR, S., TSURKALENKO, O., Zeegers, M., LEIST, A., & KRÜGER, R. (2023). Sex-specific progression of Parkinson’s disease: A longitudinal mixed-models analysis. OSF Preprint. doi:10.31219/osf.io/f64zv |
Klee, M., Aho, V., May, P., Heintz-Buschart, A., Landoulsi, Z., Jonsdottir, S., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium. (November 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome. Presentation in symposium: Social determinants of brain health: From the search for mechanisms to recommendations to increase equity [Paper presentation]. Annual Meeting of the Gerontological Society of America. |
 | Sosero, Y. L., Bandres-Ciga, S., Ferwerda, B., Tocino, M. T. P., Belloso, D. R., Gómez-Garre, P., Faouzi, J., Taba, P., PAVELKA, L., Marques, T. M., GOMES, C., KOLODKIN, A., MAY, P., Milanowski, L. M., Wszolek, Z. K., Uitti, R. J., Heutink, P., van Hilten, J. J., Simon, D. K., ... Gan-Or, Z. (2023). Dopamine pathway and Parkinson's risk variants are associated with levodopa-induced dyskinesia. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57440. doi:10.1101/2023.08.28.23294610 |
 | Yu, E., Krohn, L., Ruskey, J. A., Asayesh, F., Spiegelman, D., Shah, Z., Chia, R., Arnulf, I., Hu, M. T. M., Montplaisir, J. Y., Gagnon, J.-F., Desautels, A., Dauvilliers, Y., Gigli, G. L., Valente, M., Janes, F., Bernardini, A., Högl, B., Stefani, A., ... Gan-Or, Z. (04 July 2023). HLA in isolated REM sleep behavior disorder and Lewy body dementia. Annals of Clinical and Translational Neurology, 10 (9), 1682-1687. doi:10.1002/acn3.51841 Peer Reviewed verified by ORBi |
Klee, M., Aho, V., May, P., Heintz-Buschart, A., Landoulsi, Z., Jonsdottir, S., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium, (Other coll.). (July 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome [Poster presentation]. Alzheimer’s Association (AAIC) Conference. |
 | Arena, G., Landoulsi, Z., Grossmann, D., Vitali, A., Delcambre, S., Baron, A., Antony, P., Boussaad, I., Bobbili, D. R., Sreelatha, A. A. K., Pavelka, L., Klein, C., Seibler, P., Glaab, E., Sharma, M., Krüger, R., May, P., & Grünewald, A. (2023). Polygenic risk scores validated in patient-derived cells stratify for mitochondrial subtypes of Parkinson\textquoterights disease 2023.05.12.23289877. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55367. doi:10.1101/2023.05.12.23289877 |
 | Kaivola, K., Chia, R., Ding, J., Rasheed, M., Fujita, M., Menon, V., Walton, R. L., Collins, R. L., Billingsley, K., Brand, H., Talkowski, M., Zhao, X., Dewan, R., Stark, A., Ray, A., Solaiman, S., Alvarez Jerez, P., Malik, L., Dawson, T. M., ... Zinman, L. (2023). Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias. Cell Genomics, 100316. doi:10.1016/j.xgen.2023.100316 Peer Reviewed verified by ORBi |
 | Peiris, S., Landoulsi, Z., Pavelka, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Bobbili, D. R., Casadei, N., May, P., Krüger, R., & Consortium, T. N.-P. (2023). Accurate long-read sequencing identified GBA variants as a major genetic risk factor in the Luxembourg Parkinson\textquoterights study 2023.03.29.23287880. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55244. doi:10.1101/2023.03.29.23287880 |
 | de Nies, L., Galata, V., Martin-Gallausiaux, C., Despotovic, M., Busi, S. B., Snoeck, C. J., Delacour, L., Budagavi, D. P., Laczny, C. C., Habier, J., Lupu, P.-C., Halder, R., Fritz, J. V., Marques, T., Sandt, E., O'Sullivan, M. P., Ghosh, S., Satagopam, V., Consortium, C.-V., ... Wilmes, P. (09 March 2023). Altered infective competence of the human gut microbiome in COVID-19. Microbiome, 11 (1), 46. doi:10.1186/s40168-023-01472-7 Peer Reviewed verified by ORBi |
 | Sugier, P.-E., Lucotte, E. A., Domenighetti, C., Law, M. H., Iles, M. M., Brown, K., Amos, C., McKay, J. D., Hung, R. J., Karimi, M., Bacq-Daian, D., Boland-Augé, A., Olaso, R., Deleuze, J.-F., Lesueur, F., Ostroumova, E., Kesminiene, A., de Vathaire, F., Guénel, P., ... Elbaz, A. (14 February 2023). Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers. Movement Disorders, n/a (n/a). doi:10.1002/mds.29337 Peer Reviewed verified by ORBi |
 | Vollstedt, E.-J., Schaake, S., Lohmann, K., Padmanabhan, S., Brice, A., Lesage, S., Tesson, C., Vidailhet, M., Wurster, I., Hentati, F., Mirelman, A., Giladi, N., Karen, M., Waters, C., Fahn, S., Kasten, M., Brüggemann, N., Borsche, M., Foroud, T., ... Zimprich, A. (24 January 2023). Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort. Movement Disorders, 38 (2), 286--303. doi:10.1002/mds.29288 Peer Reviewed verified by ORBi |
 | Chemla, A., Arena, G., Saraiva, C., Berenguer-Escuder, C., Grossmann, D., Grünewald, A., Klein, C., Seibler, P., Schwamborn, J. C., & Krüger, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1. Stem Cell Research, 69, 103085. doi:10.1016/j.scr.2023.103085 Peer Reviewed verified by ORBi |
 | Chemla, A., Arena, G., Onal, G., Walter, J., Berenguer-Escuder, C., Grossmann, D., Grünewald, A., Schwamborn, J. C., & Krüger, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1. Stem Cell Research, 103145. doi:10.1016/j.scr.2023.103145 Peer reviewed |
 | Hanff, A.-M., McCrum, C., Rauschenberger, A., Aguayo, G. A., Zeegers, M. P., Leist, A., & Krüger, R. (2023). Validation of a Parkinson's disease questionnaire-39-based functional mobility composite score (FMCS) in people with Parkinson's disease. Parkinsonism & related disorders, 112, 105442. doi:10.1016/j.parkreldis.2023.105442 Peer reviewed |
Klee, M., Aho, V., May, P., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium (Other coll.). (January 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome [Poster presentation]. Conference Precision Medicine in Parkinson’s: Past lessons and conquering new frontiers. |
 | Cheng, F., Zheng, W., Liu, C., Barbuti, P. A., Yu-Taeger, L., Casadei, N., Huebener-Schmid, J., Admard, J., Boldt, K., Junger, K., Ueffing, M., Houlden, H., Sharma, M., Krüger, R., Grundmann-Hauser, K., Ott, T., & Riess, O. (23 November 2022). Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo. Science Advances, 8 (47), 6324. doi:10.1126/sciadv.abq6324 Peer Reviewed verified by ORBi |
 | Vega Moreno, C. G., Gawron, P., Lebioda, J., Groues, V., Krüger, R., Schneider, R., & Satagopam, V. (20 September 2022). SMASCH: Facilitating multi-appointment scheduling in longitudinal clinical research studies and care programs [Poster presentation]. European Conference on Computational Biology, Sitges, Spain. doi:10.5281/zenodo.6832272 |
 | Meyrath, M., Szpakowska, M., Plesseria, J.-M., Domingues, O., Langlet, J., Weber, B., Krüger, R., Ollert, M., & Chevigné, A. (09 September 2022). Nanoluciferase-based cell fusion assay for rapid and high-throughput assessment of SARS-CoV-2-neutralizing antibodies in patient samples. Methods in Enzymology, 675, 351-381. doi:10.1016/bs.mie.2022.07.015 Peer Reviewed verified by ORBi |
  | Weiss, D., Landoulsi, Z., May, P., Sharma, M., Schüpbach, M., You, H., Corvol, J. C., Paschen, S., Helmers, A.-K., Barbe, M., Fink, G., Kühn, A. A., Courbon, C. B., Wojtecki, L., Damier, P., Fraix, V., Houeto, J.-L., Regis, J., Sixel-Döring, F., ... Krüger, R. (2022). Genetic stratification of motor and QoL outcomes in Parkinson's disease in the EARLYSTIM study. Parkinsonism and Related Disorders. doi:10.1016/J.PARKRELDIS.2022.08.025 Peer Reviewed verified by ORBi |
 | Pauly, L., Hansen, M., Pauly, C., Leist, A., & Krüger, R. (September 2022). PRELIMINARY RESULTS ON THE COGNITIVE PROFILE IN PRODROMAL PARKINSON’S DISEASE – A PROSPECTIVE STUDY [Poster presentation]. Movement Disorders Society Congress 2022. |
 | Ray, A., Reho, P., Shah, Z., International LBD Genomics Consortium, May, P., Krüger, R., & Scholz, S. W. (2022). Evaluation of SORL1 in Lewy Body Dementia Identifies No Significant Associations. Movement Disorders. doi:10.1002/mds.29207 Peer Reviewed verified by ORBi |
 | Mahoney-Sanchez, L., Bouchaoui, H., Boussaad, I., Jonneaux, A., Timmerman, K., Berdeaux, O., Ayton, S., Krüger, R., Duce, J. A., Devos, D., & Devedjian, J.-C. (23 August 2022). Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition. Cell Reports, 40 (8), 111231. doi:10.1016/j.celrep.2022.111231 Peer Reviewed verified by ORBi |
 | Capelle, C., Cire, S., Hansen, M., Pavelka, L., Hedin, F., Konstantinou, M., Revets, D., Tslaf, V., Marques, T., Baron, A., Domingues, O., Zeng, N., May, P., Cosma, A., Balling, R., Krüger, R., Ollert, M., & He, F. (2022). Early-to-mid idiopathic Parkinson’s disease shows a more cytotoxic but declined CD8-regulatory peripheral immune profile. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51989. doi:10.21203/rs.3.rs-1834770/v1 |
 | Reho, P., Koga, S., Shah, Z., Chia, R., Krüger, R., May, P., Consortium, T. I. L. B. D. G., Center, T. A. G., Rademakers, R., Dalgard, C. L., Boeve, B. F., Beach, T. G., Dickson, D. W., Ross, O. A., & Scholz, S. W. (2022). GRN Mutations Are Associated with Lewy Body Dementia. Movement Disorders. doi:10.1002/mds.29144 Peer reviewed |
 | Domenighetti, C., Douillard, V., Sugier, P.-E., Sreelatha, A. A. K., Schulte, C., Grover, S., May, P., Bobbili, D. R., Radivojkov-Blagojevic, M., Lichtner, P., Singleton, A. B., Hernandez, D. G., Edsall, C., Gourraud, P.-A., Mellick, G. D., Zimprich, A., Pirker, W., Rogaeva, E., Lang, A. E., ... Consortium, E. I. P. S. D. C.-P. D. (2022). The Interaction between HLA-DRB1 and Smoking in Parkinson's Disease Revisited. Movement Disorders. doi:10.1002/mds.29133 Peer reviewed |
 | Höglinger, G., Schulte, C., Jost, W. H., Storch, A., Woitalla, D., Krüger, R., Falkenburger, B., & Brockmann, K. (31 May 2022). GBA-associated PD: chances and obstacles for targeted treatment strategies. Journal of neural transmission (Vienna, Austria : 1996), 129 (9), 1219-1233. doi:10.1007/s00702-022-02511-7 Peer reviewed |
 | Grover, S., Ashwin, A. K. S., Pihlstrom, L., Domenighetti, C., Schulte, C., Sugier, P.-E., Radivojkov-Blagojevic, M., Lichtner, P., Mohamed, O., Portugal, B., Landoulsi, Z., May, P., Bobbili, D. R., Edsall, C., Bartusch, F., Hanussek, M., Krüger, J., Hernandez, D. G., Blauwendraat, C., ... consortium, E. I. P. T. D. C.-P. D. (2022). Genome-wide Association and Meta-analysis of Age-at-Onset in Parkinson Disease: Evidence From COURAGE-PD Consortium 10.1212/WNL.0000000000200699. Neurology. doi:10.1212/WNL.0000000000200699 Peer reviewed |
 | Danileviciute, E., Zeng, N., Capelle, C. M., Paczia, N., Gillespie, M. A., Kurniawan, H., Benzarti, M., Merz, M. P., Coowar, D., Fritah, S., Vogt Weisenhorn, D. M., Gomez Giro, G., Grusdat, M., Baron, A., Guerin, C., Franchina, D. G., Léonard, C., Domingues, O., Delhalle, S., ... He, F. (26 May 2022). PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T(reg) homeostasis during ageing. Nature Metabolism, 4 (5), 589-607. doi:10.1038/s42255-022-00576-y Peer Reviewed verified by ORBi |
 | Liu, H., Dehestani, M., Blauwendraat, C., Makarious, M. B., Leonard, H., Kim, J. J., Schulte, C., Noyce, A., Jacobs, B. M., Foote, I., Sharma, M., International Parkinson's Disease Genomics Consortium, Comprehensive Unbiased Risk Factor Assessment For Environment in Parkinson's Disease Consortium, Landoulsi, Z., Krüger, R., May, P., Bobbili, D. R., Pavelka, L., Nalls, M., Singleton, A., ... Bandres-Ciga, S. (2022). Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors. Annals of Neurology. doi:10.1002/ana.26416 Peer Reviewed verified by ORBi |
 | Pauly, L., Klee, M., Paccoud, I., Satagopam, V., Ghosh, S., Fritz, J., O'Sullivan, M., Wilmes, P., Krüger, R., & Leist, A. (April 2022). Individual factors and beliefs determining COVID-19 vaccination willingness [Poster presentation]. ECCMID 2022. |
 | Pauly, L., Pauly, C., Hansen, M., Schröder, V., Rauschenberger, A., Leist, A., & Krüger, R. (2022). Retrograde Procedural Memory in Parkinson’s Disease: A Cross-Sectional, Case-Control Study. Journal of Parkinson's Disease. doi:10.3233/JPD-213081 Peer Reviewed verified by ORBi |
 | Pauly, L., Pauly, C., Hansen, M., Schröder, V., Rauschenberger, A., Leist, A., & Krüger, R. (March 2022). Retrograde Procedural Memory in Parkinson's Disease [Poster presentation]. Deutscher Kongress für Parkinson und Bewegungsstörungen 2022. doi:10.3233/JPD-213081 |
 | Langer, A., Lucke-Paulig, L., Gassner, L., Krüger, R., Weiss, D., Gharabaghi, A., Zach, H., Maetzler, W., & Hobert, M. A. (2022). Additive Effect of Dopaminergic Medication on Gait Under Single and Dual-Tasking Is Greater Than of Deep Brain Stimulation in Advanced Parkinson Disease With Long-duration Deep Brain Stimulation. Neuromodulation : journal of the International Neuromodulation Society. doi:10.1016/j.neurom.2022.01.015 Peer reviewed |
 | Domenighetti, C., Sugier, P.-E., Ashok Kumar Sreelatha, A., Schulte, C., Grover, S., Mohamed, O., Portugal, B., May, P., Bobbili, D. R., Radivojkov-Blagojevic, M., Lichtner, P., Singleton, A. B., Hernandez, D. G., Edsall, C., Mellick, G. D., Zimprich, A., Pirker, W., Rogaeva, E., Lang, A. E., ... Consortium, E. I. P. S. D. C.-P. D. (2022). Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study. Movement Disorders. doi:10.1002/mds.28902 Peer Reviewed verified by ORBi |
 | Cheng, F., Zheng, W., Barbuti, P. A., Bonsi, P., Liu, C., Casadei, N., Ponterio, G., Meringolo, M., Admard, J., Dording, C. M., Yu-Taeger, L., Nguyen, H. P., Grundmann-Hauser, K., Ott, T., Houlden, H., Pisani, A., Krüger, R., & Riess, O. (07 January 2022). DYT6 mutated THAP1 is a cell type dependent regulator of the SP1 family. Brain: a Journal of Neurology, 145 (11), 3968-3984. doi:DOI:10.1093/brain/awac001 Peer Reviewed verified by ORBi |
 | Brunelli, F., Torosantucci, L., Gelmetti, V., Franzone, D., Grünewald, A., Krüger, R., Arena, G., & Valente, E. M. (2022). PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage. Cells, 11 (4). doi:10.3390/cells11040678 Peer Reviewed verified by ORBi |
 | Vega Moreno, C. G., Gawron, P., Lebioda, J., Groues, V., Matyjaszczyk, P., Pauly, C., Smula, E., Krüger, R., Schneider, R., & Satagopam, V. (2022). Smart Scheduling (SMASCH): multi-appointment scheduling system for longitudinal clinical research studies. JAMIA Open, 5 (2), 038. doi:10.1093/jamiaopen/ooac038 Peer Reviewed verified by ORBi |
 | Pauly, C., Glaab, E., Hansen, M., Martin-Gallausiaux, C., Ledda, M., Marques, T., Wilmes, P., Krüger, R., & Consortium, N.-P. (2022). Parkinson's Disease progression, resilience and inflammation markers during the COVID-19 pandemic. Movement Disorders, in press (doi: 10.1002/mds.29212) (in press). doi:10.1002/mds.29212 Peer Reviewed verified by ORBi |
 | Pavelka, L., Rauschenberger, A., Landoulsi, Z., Pachchek, S., Marques, T., Gomes, C., Glaab, E., May, P., Krüger, R., & NCER-PD, C. (2022). Body-First Subtype of Parkinson's Disease with Probable REM-Sleep Behavior Disorder Is Associated with Non-Motor Dominant Phenotype. Journal of Parkinson's Disease. doi:10.3233/JPD-223511 Peer Reviewed verified by ORBi |
 | Pavelka, L., Rauschenberger, A., Landoulsi, Z., Pachchek, S., May, P., Glaab, E., NCER-PD, C., & Krüger, R. (Other coll.). (2022). Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes. NPJ Parkinson's Disease, 9 (8), 102. doi:10.1038/s41531-022-00342-7 Peer Reviewed verified by ORBi |
 | Fründt, O., Hanff, A.-M., Mai, T., Kirchner, C., Bouzanne des Mazery, E., Amouzandeh, A., Buhmann, C., Krüger, R., & Südmeyer, M. (2022). Impact of COVID-19 Pandemic on (Health) Care Situation of People with Parkinson’s Disease in Germany (Care4PD). Brain Sciences, 12 (1 62). doi:10.3390/brainsci12010062 Peer Reviewed verified by ORBi |
 | Zeng, N.* , Capelle, C. M.* , Baron, A., Kobayashi, T., Cire, S., Tslaf, V., Leonard, C., Coowar, D., Koseki, H., Westendorf, A. M., Buer, J., Brenner, D., Krüger, R., Balling, R., Ollert, M., & He, F. (2022). DJ‐1 depletion prevents immunoaging in T‐cell compartments. EMBO Reports, 23 (3). doi:10.15252/embr.202153302 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Arena, G., Sharma, K., Agyeah, G., Krüger, R., Grünewald, A., & Fitzgerald, J. C. (2022). Neurodegeneration and Neuroinflammation in Parkinson’s Disease: a Self-Sustained Loop. Current Neurology and Neuroscience Reports, 22 (8), 427 – 440. doi:10.1007/s11910-022-01207-5 Peer reviewed |
 | Bowring, F., Welch, J., Woodward, C., Lo, C., Lawton, M., Sulzer, P., Hanff, A.-M., Krüger, R., Liepelt-Scarfone, I., & Hu, M. T. (2022). Exploration of whether socioeconomic factors affect the results of priority setting partnerships: updating the top 10 research priorities for the management of Parkinson's in an international setting. BMJ Open, 12 (6), 049530. doi:10.1136/bmjopen-2021-049530 Peer Reviewed verified by ORBi |
 | Hanff, A.-M., Leist, A., Fritz, J., Pauly, C., Krüger, R., Halek, M., & NCER-PD, C. (2021). Determinants of Self-Stigma in People with Parkinson's Disease: A Mixed Methods Scoping Review. Journal of Parkinson's Disease. doi:10.3233/JPD-212869 Peer Reviewed verified by ORBi |
 | Leist, A., Klee, M., Paccoud, I., Pauly, L., Ghosh, S., Fritz, J., O Sullivan, M. P., Rommes, B., Wilmes, P., Krüger, R., & CON-VINCE Consortium. (2021). Which demographic and socio-economic factors are associated with vaccination willingness and beliefs towards vaccination? Rapid report with first results. |
 | Barbuti, P. A., Ohnmacht, J., Santos, B. F., Antony, P., Massart, F., Cruciani, G., Dording, C. M., Pavelka, L., Casadei, N., Kwon, Y.-J., & Krüger, R. (09 November 2021). Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports, 11, 21946. doi:10.1038/s41598-021-01505-x Peer Reviewed verified by ORBi |
 | Bremm, R. P., Berthold, C., Krüger, R., Koch, K. P., Goncalves, J., & Hertel, F. (2021). Therapeutic maps for a sensor-based evaluation of deep brain stimulation programming. Biomedizinische Technik. Biomedical Engineering. doi:10.1515/bmt-2020-0210 Peer Reviewed verified by ORBi |
 | Kaivola, K., Shah, Z., Chia, R., International LBD Genomics Consortium, May, P., Krüger, R., & Scholz, S. W. (25 October 2021). Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups. Brain: a Journal of Neurology, awab402. doi:10.1093/brain/awab402 Peer Reviewed verified by ORBi |
 | Domenighetti, C., Sugier, P. E., Sreelatha, A. A. K., Schulte, C., Grover, S., Mohamed, O., Portugal, B., May, P., Bobbili, D. R., Radivojkov-Blagojevic, M., Lichtner, P., Singleton, A. B., Hernandez, D. G., Edsall, C., Mellick, G. D., Zimprich, A., Pirker, W., Rogaieva, E., Lang, A. E., ... Elbaz, A. (2021). Mendelian randomization study of smoking, alcohol, and coffee drinking in relation to Parkinso's disease. Journal of Parkinson's Disease, 1-16. doi:10.3233/JPD-212851 Peer Reviewed verified by ORBi |
Leist, A., Wilmes, P., Krüger, R., & NCER-PD Consortium. (2021). Zusammenhänge zwischen sozio-ökonomischem Status und Darmmikrobiom als Risiko für Demenz [Paper presentation]. Journée de Gérontologie, Dommeldange, Luxembourg. |
Bolognin, S., Smits, L., Nickels, S. L., Magni, S., Antony, P., Grzyb, K., Krüger, R., Skupin, A., & Schwamborn, J. C. (2021). A new brain organoid model to study Parkinson’s Disease. Biomedical Science and Engineering. |
 | Pauly, L., Rauschenberger, A., Pauly, C., Hansen, M., Pavelka, L., Hanff, A.-M., Schröder, V., Leist, A., & Krüger, R. (17 September 2021). The retrograde procedural memory in people with Parkinson’s disease with or without freezing of gait – a cross-sectional study [Poster presentation]. Movement Disorders Society Congress 2021. |
 | Ribeiro, F., Schröder, V., Krüger, R., Leist, A., & the CON-VINCE Consortium. (September 2021). The evolution and social determinants of mental health during the first wave of the COVID-19 outbreak in Luxembourg. Psychiatry Research, 303. doi:10.1016/j.psychres.2021.114090 Peer Reviewed verified by ORBi |
 | Zeng, N., Capelle, C., Baron, A., Cire, S., Leonard, C., Coowar, D., Koseki, H., Westendorf, A., Buer, J., Brenner, D., Krüger, R., Balling, R., Ollert, M., & He, F. (2021). DJ-1 depletion slows down immunoaging in T-cell compartments. bioRxiv. doi:10.1101/2021.05.21.445139 |
 | Krüger, R., The Global Parkinson's Genetics Program, & The Global Parkinson's Genetics Program. (April 2021). GP2: The Global Parkinson's Genetics Program. Movement Disorders, 36 (4), 842-851. doi:10.1002/mds.28494 Peer Reviewed verified by ORBi |
 | Grover, S., Kumar-Sreelatha, A. A., Bobbili, D. R., May, P., Domenighetti, C., Sugier, P.-E., Schulte, C., COURAGE-PD Consortium, Elbaz, A., Krüger, R., Gasser, T., & Sharma, M. (2021). Replication of a Novel Parkinson's Locus in a European Ancestry Population. Movement Disorders. doi:10.1002/mds.28546 Peer reviewed |
 | Krüger, R., Pavelka, L., Mollenhauer, B., Bloem, B., van Rumund, A., Esselink, R. A. J., Geurtz, B. P. M., Wevers, R. A., & Verbeek, M. M. (2021). Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase. NPJ Parkinson's Disease. doi:10.1038/s41531-021-00172-z Peer Reviewed verified by ORBi |
 | Krüger, R., Kern, F., Fehlmann, T., Violich, I., Hutchins, E., Alsop, E., Kahraman, M., Grammes, N., Balling, R., Geffers, L., & Keller, A. (2021). Deep sequencing of sncRNAs reveals hallmarks and regulatory modules of the transcriptome during Parkinson’s disease progression. Nature Aging. doi:10.1038/s43587-021-00042-6 Peer Reviewed verified by ORBi |
 | Chia, R., Sabir, M. S., Bandres-Ciga, S., Saez-Atienzar, S., Reynolds, R. H., Gustavsson, E., Walton, R. L., Ahmed, S., Viollet, C., Ding, J., Makarious, M. B., Diez-Fairen, M., Portley, M. K., Shah, Z., Abramzon, Y., Hernandez, D. G., Blauwendraat, C., Stone, D. J., Eicher, J., ... Scholz, S. W. (2021). Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature Genetics. doi:10.1038/s41588-021-00785-3 Peer Reviewed verified by ORBi |
 | Dewan, R., Chia, R., Ding, J., Hickman, R. A., Stein, T. D., Abramzon, Y., Ahmed, S., Sabir, M. S., Portley, M. K., Tucci, A., Ibáñez, K., Shankaracharya, F. N. U., Keagle, P., Rossi, G., Caroppo, P., Tagliavini, F., Waldo, M. L., Johansson, P. M., Nilsson, C. F., ... Traynor, B. J. (03 February 2021). Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Neuron, 109 (3), 448-460. doi:10.1016/j.neuron.2020.11.005 Peer Reviewed verified by ORBi |
 | Mencke, P., Boussaad, I., Romano, C., Kitami, T., Linster, C., & Krüger, R. (2021). The Role of DJ-1 in Cellular Metabolism and Pathophysiological Implications for Parkinson’s Disease. Cells. doi:10.3390/cells10020347 Peer Reviewed verified by ORBi |
 | Holuka, C., Snoeck, C. J., Mériaux, S. B., Ollert, M., Krüger, R., Turner, J., & The Con-Vince Consortium. (2021). Adverse Life Trajectories Are a Risk Factor for SARS-CoV-2 IgA Seropositivity. Journal of Clinical Medicine, 10 (10). doi:10.3390/jcm10102159 Peer Reviewed verified by ORBi |
 | Wolf, C., Pouya, A., Bitar, S., Pfeiffer, A., Bueno, D., Arndt, S., Tenzer, S., Dal Bello, F., Vianello, C., Ritz, S., Schwirz, J., Dobrindt, K., Peitz, M., Hanschmann, E.-M., Boussaad, I., Brüstle, O., Giacomello, M., Krüger, R., & Methner, A. (2021). GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton 2021.03.04.433895. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/50307. doi:10.1101/2021.03.04.433895 |
 | Brown, S. J., Boussaad, I., Jarazo, J., Fitzgerald, J. C., Antony, P., Keatinge, M., Blechman, J., Schwamborn, J. C., Krüger, R., Placzek, M., & Bandmann, O. (2021). PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-021-84278-7 Peer Reviewed verified by ORBi |
 | Boussaad, I., Cruciani, G., Bolognin, S., Antony, P., Dording, C., Kwon, Y.-J., Heuting, P., Fava, E., Schwamborn, J. C., & Krüger, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3 Peer Reviewed verified by ORBi |
 | Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L., Su, J., Arias-Fuenzalida, Walter, J., Gomez Giro, G., Monzel, A., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., ... Schwamborn, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 Peer Reviewed verified by ORBi |
 | Pauly, C., Ribeiro, F., Schröder, V., Pauly, L., Krüger, R., & Leist, A. (2021). The Moderating Role of Resilience in the Personality-Mental Health Relationship During the COVID-19 Pandemic. Frontiers in Psychiatry. doi:10.3389/fpsyt.2021.745636 Peer Reviewed verified by ORBi |
 | Walter, J., Bolognin, S., Poovathingal, S., Magni, S., Gerard, D., Antony, P., Nickels, S. L., Salamanca, L., Berger, E., Smits, L., Grzyb, K., Perfeito, R., Hoel, F., Qing, X., Ohnmacht, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... Schwamborn, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864 Peer Reviewed verified by ORBi |
 | Becker, S., Pauly, C., Lawton, M., Hipp, G., Bowring, F., Sulzer, P., Hu, M., Krüger, R., Gasser, T., & Liepelt-Scarfone, I. (2021). Quantifying activities of daily living impairment in Parkinson’s disease using the Functional Activities Questionnaire. Neurological Sciences. doi:10.1007/s10072-021-05365-1 Peer Reviewed verified by ORBi |
 | Arena, G., & Krüger, R. (2021). Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease: the PINK1/CHCHD4 interplay. Neural Regeneration Research. doi:10.4103/1673-5374.310679 Peer Reviewed verified by ORBi |
 | Farrer, M. J., Bardien, S., Hattori, N., Lesage, S., Ross, O. A., Mellick, G. D., & Krüger, R. (2021). Editorial: Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson's Disease. Frontiers in Neurology, 12. doi:10.3389/fneur.2021.648417 Peer Reviewed verified by ORBi |
 | Bremm, R. P., Koch, K. P., Krüger, R., Goncalves, J., & Hertel, F. (26 November 2020). Analysis and visualisation of tremor dynamics in deep brain stimulation patients. Current Directions in Biomedical Engineering, 6 (3), 4. doi:10.1515/cdbme-2020-3030 Peer Reviewed verified by ORBi |
 | Bremm, R. P., Koch, K. P., Krüger, R., Hertel, F., & Goncalves, J. (26 November 2020). A rule-based expert system for real-time feedback-control in deep brain stimulation. Current Directions in Biomedical Engineering, 6 (3), 4. doi:10.1515/cdbme-2020-3027 Peer Reviewed verified by ORBi |
 | Fehlmann, T., Lehallier, B., Schaum, N., Hahn, O., Kahraman, M., Li, Y., Grammes, N., Geffers, L., Backes, C., Balling, R., Kern, F., Krüger, R., Lammert, F., Ludwig, N., Meder, B., Fromm, B., Maetzler, W., Berg, D., Brockmann, K., ... Keller, A. (24 November 2020). Common diseases alter the physiological age-related blood microRNA profile. Nature Communications, 11 (1), 5958. doi:10.1038/s41467-020-19665-1 Peer Reviewed verified by ORBi |
 | Zanin, M., Santos, B. F. R., Antony, P., Berenguer-Escuder, C., Larsen, S. B., Hanss, Z., Barbuti, P., Baumuratov, A., Grossmann, D., Capelle, C. M., Weber, J., Balling, R., Ollert, M., Krüger, R., Diederich, N. J., & He, F. (10 November 2020). Mitochondria interaction networks show altered topological patterns in Parkinson's disease. NPJ Systems Biology and Applications, 6 (1), 38. doi:10.1038/s41540-020-00156-4 Peer Reviewed verified by ORBi |
 | Hanss, Z., Larsen, S., Antony, P., Mencke, P., Massart, F., Jarazo, J., Schwamborn, J. C., Barbuti, P., Mellick, G., & Krüger, R. (2020). Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient-Derived Neurons. Movement Disorders. doi:10.1002/mds.28365 Peer Reviewed verified by ORBi |
 | Neumann, M. A.-C.* , Grossmann, D.* , Schimpf-Linzenbold, S., Dayan, D., Stingl, K., Ben-Menachem, R., Pines, O., Massart, F., Delcambre, S., Ghelfi, J., Bohler, J., Strom, T., Kessel, A., Azem, A., Schöls, L., Grünewald, A., Wissinger, B., & Krüger, R. (2020). Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy. Scientific Reports. doi:10.1038/s41598-020-73557-4 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Barbuti, P., Santos, B., Dording, C., Cruciani, G., Massart, F., Hummel, A., & Krüger, R. (October 2020). Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA. Stem Cell Research, 48, 101951. doi:10.1016/j.scr.2020.101951 Peer Reviewed verified by ORBi |
 | Mencke, P., Hanss, Z., Boussaad, I., Sugier, P.-E., Elbaz, A., & Krüger, R. (2020). Bidirectional Relation Between Parkinson’s Disease and Glioblastoma Multiforme. Frontiers in Neurology. doi:10.3389/fneur.2020.00898 Peer reviewed |
 | Chia, R., Sabir, M. S., Bandres-Ciga, S., Saez-Atienzar, S., Reynolds, R. H., Gustavsson, E., Walton, R. L., Ahmed, S., Viollet, C., Ding, J., Makarious, M. B., Diez-Fairen, M., Portley, M. K., Shah, Z., Abramzon, Y., Hernandez, D. G., Blauwendraat, C., Stone, D. J., Eicher, J., ... Scholz, S. W. (2020). Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/44713. doi:10.1101/2020.07.06.185066 |
 | Rajan, R., Divya, K. P., Kandadai, R. M., Yadav, R., Satagopam, V., Madhusoodanan, U. K., Agarwal, P., Kumar, N., Ferreira, T., Kumar, H., Sreeram Prasad, A. V., Shetty, K., Mehta, S., Desai, S., Kumar, S., Prashanth, L. K., Bhatt, M., Wadia, P., Ramalingam, S., ... Sharma, M. (18 June 2020). Genetic Architecture of Parkinson's Disease in the Indian Population: Harnessing Genetic Diversity to Address Critical Gaps in Parkinson's Disease Research. Frontiers in Neurology, 11, 524. doi:10.3389/fneur.2020.00524 Peer Reviewed verified by ORBi |
 | Krüger, R., Baldini, F., Thiele, I., Hertel, J., & NCER-PD Consortium. (2020). Parkinson’s disease-associated alterations of the gut microbiome predict diseaserelevant changes in metabolic functions. BMC Biology. doi:10.1186/s12915-020-00775-7 Peer Reviewed verified by ORBi |
 | Kern, F., Fehlmann, T., Violich, I., Alsop, E., Hutchins, E., Kahraman, M., Grammes, N. L., Guimarães, P., Backes, C., Poston, K., Casey, B., Balling, R., Geffers, L., Krüger, R., Galasko, D., Mollenhauer, B., Meese, E., Wyss-Coray, T., Craig, D. W., ... Keller, A. (2020). Deep sncRNA-seq of the PPMI cohort to study Parkinson’s disease progression. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/44658. doi:10.1101/2020.06.01.127092 |
 | Krüger, R., & Stute, L. (2020). Emerging concepts for precision medicine in Parkinson's disease with focus on genetics. Fortschritte der Neurologie-Psychiatrie. doi:10.1055/a-1149-2204 Peer Reviewed verified by ORBi |
 | Snoeck, C. J., Vaillant, M., Abdelrahman, T., Satagopam, V., Turner, J., Beaumont, K., Gomes, C., Fritz, J., Schröder, V., Kaysen, A., Pavelka, L., Stute, L., Ramos Meyers, G., Pauly, L., Hansen, M., Pauly, C., Aguayo, G. A., Perquin, M., Hanff, A.-M., ... Krüger, R. (2020). Prevalence of SARS-CoV-2 infection in the Luxembourgish population: the CON-VINCE study. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/44961. doi:10.1101/2020.05.11.20092916 |
 | Ohnmacht, J., May, P., Sinkkonen, L., & Krüger, R. (2020). Missing heritability in Parkinson’s disease: the emerging role of non‑coding genetic variation. Journal of Neural Transmission. doi:10.1007/s00702-020-02184-0 Peer Reviewed verified by ORBi |
 | Larsen, S., Hanss, Z., Cruciani, G., Massart, F., Barbuti, P., Mellick, G., & Krüger, R. (2020). Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35. Stem Cell Research. doi:10.1016/j.scr.2020.101776 Peer Reviewed verified by ORBi |
 | Schröder, V., Kaysen, A., Fritz, J., Kemp, J., Wagner, S., Köhler, S., Hartmann, T., Dodel, R., Kalbe, E., Leist, A., & Krüger, R. (April 2020). Programme Démence Prévention (pdp ): A Nation-Wide Programme for Dementia Prevention in Luxembourg [Poster presentation]. Advances in Alzheimer's and Parkinson's Therapies AAT-AD/PD Focus Meeting. |
 | Woitalla, D., Krüger, R., Lorenzl, S., Müller, T., Oelwein, G., Storch, A., Wolz, M., & Wüllner, U. (2020). Grundlagen und Stellenwert der COMT- und MAO-B-Inhibitoren in der Therapie des idiopathischen Parkinson-Syndroms. Fortschritte der Neurologie-Psychiatrie. doi:10.1055/a-1149-9308 Peer Reviewed verified by ORBi |
 | Fehlmann, T., Kahraman, M., Backes, C., Galata, V., Keller, V., Geffers, L., Mercaldo, N., Hornung, D., Keller, A., Krüger, R., & Balling, R. (2020). Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients. JAMA Oncology. doi:10.1001/jamaoncol.2020.0001 Peer Reviewed verified by ORBi |
 | Bobbili, D. R., Banda, P., Krüger, R., & May, P. (2020). Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk. Journal of Medical Genetics. doi:10.1136/jmedgenet-2019-106316 Peer Reviewed verified by ORBi |
 | Krüger, R., Balling, R., Antony, P., Kondratyeva, O., Ostaszewski, M., Baumuratov, A., Grossmann, D., Mommaerts, K., Sokolowska, K., Longhino, L., Poulain, J. F., & Diederich, N. J. (2020). Fibroblast mitochondria in idiopathic Parkinson’s disease display morphological changes and enhanced resistance to depolarization. Scientific Reports. doi:10.1038/s41598-020-58505-6 Peer Reviewed verified by ORBi |
 | Krüger, R., Cheng, F., Walter, M., Riess, O., Wassouf, Z., Hentrich, T., Schulze-Hentrich, J., Barbuti, P., Grundmann-Hauser, K., Ott, T., & Casadei, N. (2020). Unraveling Molecular Mechanisms of THAP1 Missense Mutations in DYT6 Dystonia. Journal of Molecular Neuroscience. doi:10.1007/s12031-020-01490-2 Peer Reviewed verified by ORBi |
 | Meyrath, M., Szpakowska, M., Zeiner, J., Massotte, L., Merz, M. P., Benkel, T., Simon, K., Ohnmacht, J., Turner, J., Krüger, R., Seutin, V., Ollert, M., Kostenis, E., & Chevigné, A. (2020). The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nature Communications, 11 (1), 3033. doi:10.1038/s41467-020-16664-0 Peer Reviewed verified by ORBi |
 | Bus, C., Zizmare, L., Feldkaemper, M., Geisler, S., Zarani, M., Schaedler, A., Klose, F., Admard, J., Mageean, C. J., Arena, G., Fallier-Becker, P., Ugun-Klusek, A., Maruszczak, K. K., Kapolou, K., Schmid, B., Rapaport, D., Ueffing, M., Casadei, N., Krüger, R., ... Fitzgerald, J. C. (2020). Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors. iScience, 23 (12), 101797. doi:10.1016/j.isci.2020.101797 Peer Reviewed verified by ORBi |
 | Grossmann, D., Berenguer-Escuder, C., Chemla, A., Arena, G., & Krüger, R. (2020). The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease. Frontiers in Neurology, 11, 587. doi:10.3389/fneur.2020.00587 Peer Reviewed verified by ORBi |
 | Binck, S., Pauly, C., Vaillant, M., Hipp, G., Gantenbein, M., Krüger, R., & Diederich, N. J. (2020). Contributing Factors and Evolution of Impulse Control Disorder in the Luxembourg Parkinson Cohort. Frontiers in Neurology, 11, 578924. doi:10.3389/fneur.2020.578924 Peer Reviewed verified by ORBi |
 | Barbuti, P., Antony, P., Rodrigues Santos, B., Massart, F., Cruciani, G., Dording, C., Arias, J., Schwamborn, J. C., & Krüger, R. (2020). Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson's Disease Point Mutation A30P. Cells, 9 (9). doi:10.3390/cells9092065 Peer Reviewed verified by ORBi |
 | Klucken, J., Winkler, J., Krüger, R., & Jost, W. (2020). Die Geschichte des ‚Freezing-of-gait‘ beim Parkinson-Syndrom – vom Phänomen zum Symptom. Fortschritte der Neurologie-Psychiatrie, 88 (9), 573-581. doi:10.1055/a-1227-6258 Peer Reviewed verified by ORBi |
 | Berenguer-Escuder, C., Grossmann, D., Antony, P., Arena, G., Wasner, K., Massart, F., Jarazo, J., Walter, J., Schwamborn, J. C., Grünewald, A., & Krüger, R. (2020). Impaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease. Human Molecular Genetics. doi:10.1093/hmg/ddaa066 Peer Reviewed verified by ORBi |
 | Monzel, A. S., Hemmer, K., Smits, L., Bolognin, S., Lucarelli, P., Rosety, I., Zagare, A., Antony, P., Nickels, S., Krüger, R., & Schwamborn, J. C. (2020). Machine learning-assisted neurotoxicity prediction in human midbrain organoids. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2020.05.011 Peer Reviewed verified by ORBi |
 | Hanff, A.-M., Pauly, C., Pauly, L., Schröder, V., Hansen, M., Meyers, G. R., Kaysen, A., Hansen, L., Wauters, F., & Krüger, R. (2020). Unmet Needs of People With Parkinson's Disease and Their Caregivers During COVID-19-Related Confinement: An Explorative Secondary Data Analysis. Frontiers in Neurology, 11, 615172. doi:10.3389/fneur.2020.615172 Peer Reviewed verified by ORBi |
 | Boussaad, I., Obermaier, C. D., Hanss, Z., Bobbili, D. R., Bolognin, S., Glaab, E., Wołyńska, K., Weisschuh, N., De Conti, L., May, C., Giesert, F., Grossmann, D., Lambert, A., Kirchen, S., Biryukov, M., Burbulla, L. F., Massart, F., Bohler, J., Cruciani, G., ... Krüger, R. (2020). A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease. Science Translational Medicine, 12 (560). doi:10.1126/scitranslmed.aau3960 Peer Reviewed verified by ORBi |
 | Berenguer, C., Grossmann, D., Massart, F., Antony, P., Burbulla, L., Glaab, E., Imhoff, S., Trinh, J., Seibler, P., Grünewald, A., & Krüger, R. (2019). Variants in Miro1 cause alterations of ER-mitochondria contact sites in fibroblasts from Parkinson's disease patients. Journal of Clinical Medicine. doi:10.3390/jcm8122226 Peer Reviewed verified by ORBi |
 | Krüger, R., & Kolber, P. L. (2019). Gene-environment interaction and Mendelian randomisation. Revue Neurologique. doi:10.1016/j.neurol.2019.04.010 Peer Reviewed verified by ORBi |
 | Simons, J., Vaillant, M., Hipp Epouse D'amico, G., Pavelka, L., Stute, L., Pauly, C., & Krüger, R. (2019). Multilingual Validation of the First French Version of Munich Dysphagia Test-Parkinson's Disease (MDT-PD) in the Luxembourg Parkinson's Study. Frontiers in Neurology. doi:10.3389/fneur.2019.01180 Peer Reviewed verified by ORBi |
 | Schymanski, E., Baker, N. C., Williams, A. J., Singh, R., Trezzi, J.-P., Kolber, P. L., Wilmes, P., Krüger, R., Paczia, N., Linster, C., & Balling, R. (2019). Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges. Environmental Science. Processes and Impacts. doi:10.1039/C9EM00068B Peer Reviewed verified by ORBi |
 | Krüger, R., EARLYSTIM study group, & Barbe, M. (2019). Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease With Early Motor Complications. Movement Disorders. doi:10.1002/mds.27892 Peer Reviewed verified by ORBi |
 | Grossmann, D., Berenguer, C., Bellet, M. E., Scheibner, D., Bohler, J., Massart, F., Rapaport, D., Skupin, A., Fouquier d'Hérouël, A., Sharma, M., Ghelfi, J., Rakovic, A., Lichtner, P., Antony, P., Glaab, E., May, P., Dimmer, K. S., Fitzgerald, J. C., Grünewald, A., & Krüger, R. (2019). Mutations in RHOT1 disrupt ER-mitochondria contact sites interfering with calcium homeostasis and mitochondrial dynamics in Parkinson's disease. Antioxidants & redox signaling. doi:10.1089/ars.2018.7718 Peer reviewed |
 | Arias, J., Jarazo, J., Walter, J., Gomez Giro, G., Forster, J., Antony, P., Krüger, R., & Schwamborn, J. C. (2019). Automated high-throughput high-content autophagy and mitophagy analysis platform. Scientific Reports. doi:10.1038/s41598-019-45917-2 Peer Reviewed verified by ORBi |
 | Krüger, R., Riederer, P., Berg, D., Casadei, N., Cheng, F., Claßen, J., Dresel, C., & Jost, W. (2019). α-Synuclein in Parkinson's disease: causal or bystander? Journal of Neural Transmission. doi:10.1007/s00702-019-02025-9 Peer Reviewed verified by ORBi |
 | Krüger, R., Vollstedt, E. J., Kasten, M., Klein, C., & MJFF Global Genetic Parkinson's Disease Study Group. (2019). Using global team science to identify genetic parkinson's disease worldwide. Annals of Neurology. doi:10.1002/ana.25514 Peer Reviewed verified by ORBi |
Smits, L., Magni, S., Grzyb, K., Antony, P., Krüger, R., Skupin, A., Bolognin, S., & Schwamborn, J. C. (2019). Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/39342. doi:10.1101/589598 |
 | Krüger, R., Gerlach, M., Sharma, M., Romanos, M., Lech, K. P., Walitza, S., Conzelmann, A. H., & Renner, T. R. (2019). Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder. ADHD Attention Deficit and Hyperactivity Disorders. doi:10.1007/s12402-019-00286-8 Peer reviewed |
 | Krüger, R., EARLYSTIM study group, Schuepbach, M., & Deuschl, G. (2019). Quality of life predicts outcome of deep brain stimulation in early Parkinson disease. Neurology. doi:10.1212/WNL.0000000000007037 Peer Reviewed verified by ORBi |
 | Hertel, J., Harms, A. C., Heinken, A., Baldini, F., Thinnes, C. C., Glaab, E., Vasco, D., Pietzner, M., Stewart, I. D., Wareham, N. J., Langenberg, C., Trenkwalder, C., Krüger, R., Hankemeier, T., Fleming, R. M. T., Mollenhauer, B., & Thiele, I. (2019). Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease. Cell Reports, 29 (7), 1767-1777. doi:10.1016/j.celrep.2019.10.035 Peer Reviewed verified by ORBi |
 | Hanss, Z., Boussaad, I., Jarazo, J., Schwamborn, J. C., & Krüger, R. (2019). Quality Control Strategy for CRISPRCas9- based Gene Editing Complicated by a Pseudogene. Frontiers in Genetics. doi:10.3389/fgene.2019.01297 Peer Reviewed verified by ORBi |
 | Schoellmann, A., Scholten, M., Wasserka, B., Govindan, R. B., Krüger, R., Gharabaghi, A., Plewnia, C., & Weiss, D. (2019). Anodal tDCS modulates cortical activity and synchronization in Parkinson's disease depending on motor processing. NeuroImage: Clinical, 22, 101689. doi:10.1016/j.nicl.2019.101689 Peer Reviewed verified by ORBi |
 | Keller, A., Fehlmann, T., Laufer, T., Backes, C., Kahramann, M., Alles, J., Fischer, U., Minet, M., Ludwig, N., Kern, F., Kehl, T., Galata, V., Dusterloh, A., Schrors, H., Kohlhaas, J., Bals, R., Huwer, H., Geffers, L., Krüger, R., ... Meese, E. (2018). Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity. RNA Biology. doi:10.1080/15476286.2018.1559689 Peer Reviewed verified by ORBi |
 | Krüger, R., Klucken, J., Bloem, B., & Schimdt, P. (2018). Management of Parkinson’s Disease 20 Years from Now: Towards Digital Health Pathways. Journal of Parkinson's Disease. doi:10.3233/JPD-181519 Peer Reviewed verified by ORBi |
 | Krüger, R., Kishore, A., Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease (COURAGE-PD), & Sreelatha, A. A. K. (2018). Understanding the role of genetic variability in LRRK2 in Indian population. Movement Disorders. doi:10.1002/mds.27558 Peer Reviewed verified by ORBi |
 | Hipp Epouse D'amico, G., Vaillant, M., Diederich, N. J., Roomp, K., Satagopam, V., Banda, P., Sandt, E., Mommaerts, K., Schmitz, S., Longhino, L., Schweicher, A., Hanff, A.-M., Nicolai, B., Kolber, P. L., Reiter, D., Pavelka, L., Binck, S., Pauly, C., Geffers, L., ... Krüger, R. (29 October 2018). The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis. Frontiers in Aging Neuroscience, 10, 326. doi:10.3389/fnagi.2018.00326 Peer Reviewed verified by ORBi |
 | Krüger, R., Blauwendraat, C., & International Parkinson's Disease Genomics Consortium (IPDGC), COURAGE-PD Consortium. (2018). Insufficient Evidence for Pathogenicity of SNCA His50Gln (H50Q) in Parkinson's Disease. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2017.12.012 Peer Reviewed verified by ORBi |
 | Fitzgerald, J. C., Zimprich, A., Bobbili, D. R., Sharma, M., May, P., & Krüger, R. (2018). Reply: No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson’s disease. Brain: a Journal of Neurology. doi:10.1093/brain/awx380 Peer Reviewed verified by ORBi |
 | Krüger, R., Larsen, S., & Hanss, Z. (2018). The genetic architecture of mitochondrial dysfunction in Parkinson's Disease. Cell and Tissue Research. doi:10.1007/s00441-017-2768-8 Peer reviewed |
 | Riederer, P., Jellinger, K. A., Kolber, P. L., Hipp, G., Sian-Hulsmann, J., & Krüger, R. (2018). Lateralisation in Parkinson disease. Cell and Tissue Research, 373 (1), 297-312. doi:10.1007/s00441-018-2832-z Peer Reviewed verified by ORBi |
 | Lhommee, E., Wojtecki, L., Czernecki, V., Witt, K., Maier, F., Tonder, L., Timmermann, L., Halbig, T. D., Pineau, F., Durif, F., Witjas, T., Pinsker, M., Mehdorn, M., Sixel-Doring, F., Kupsch, A., Krüger, R., Elben, S., Chabardes, S., Thobois, S., ... Krack, P. (2018). Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial. The Lancet. Neurology, 17 (3), 223-231. doi:10.1016/S1474-4422(18)30035-8 Peer reviewed |
 | Harmuth, T., Prell-Schicker, C., Weber, J. J., Gellerich, F., Funke, C., Driessen, S., Magg, J. C. D., Krebiehl, G., Wolburg, H., Hayer, S. N., Hauser, S., Krüger, R., Schols, L., Riess, O., & Hubener-Schmid, J. (2018). Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3. Frontiers in Molecular Neuroscience, 11, 368. doi:10.3389/fnmol.2018.00368 Peer Reviewed verified by ORBi |
 | Hanci, I., Kamm, C., Scholten, M., Roncoroni, L. P., Weber, Y., Krüger, R., Plewnia, C., Gharabaghi, A., & Weiss, D. (2018). Long-Term Effect of GPi-DBS in a Patient With Generalized Dystonia Due to GLUT1 Deficiency Syndrome. Frontiers in Neurology, 9, 381. doi:10.3389/fneur.2018.00381 Peer Reviewed verified by ORBi |
 | Burbulla, L. F., Song, P., Mazzulli, J. R., Zampese, E., Wong, Y. C., Jeon, S., Santos, D. P., Blanz, J., Obermaier, C. D., Strojny, C., Savas, J. N., Kiskinis, E., Zhuang, X., Krüger, R., Surmeier, D. J., & Krainc, D. (22 September 2017). Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science, 357 (6357), 1255-1261. doi:10.1126/science.aam9080 Peer Reviewed verified by ORBi |
 | Fitzgerald, J. C., Zimprich, A., Carvajal-Berrio, D. A., Schindler, K. M., Maurer, B., Schulte, C., Bus, C., Hauser, A.-K., Kübler, M., Lewin, R., Bobbili, D. R., Schwarz, L. M., Vartholomaiou, E., Brockmann, K., Wüst, R., Madlung, J., Nordheim, A., Riess, O., Martins, L. M., ... Krüger, R. (24 August 2017). Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease. Brain: a Journal of Neurology, 140 (9), 2444-2459. doi:10.1093/brain/awx202 Peer Reviewed verified by ORBi |
 | Krüger, R., Lingor, P., Doskas, T., Henselmans, J. M. L., Danielsen, E. H., de Fabregues, O., Stefani, A., Sensken, S.-C., Parra, J. C., Onuk, K., Yegin, A., & Antonini, A. (2017). An Observational Study of the Effect of Levodopa-Carbidopa Intestinal Gel on Activities of Daily Living and Quality of Life in Advanced Parkinson's Disease Patients. Advances in Therapy. doi:10.1007/s12325-017-0571-2 Peer Reviewed verified by ORBi |
 | Bobbili, D. R., May, P., & Krüger, R. (02 June 2017). Rare variant analysis of the PPMI dataset to uncover the complex genetic architecture of Parkinson’s disease. Movement Disorders, 322 (Supplement S2), 405. doi:10.1002/mds.27087 Peer Reviewed verified by ORBi |
 | Seidel, K., Bouzrou, M., Heidemann, N., Krüger, R., Schols, L., den Dunnen, W. F. A., Korf, H.-W., & Rub, U. (June 2017). Involvement of the cerebellum in Parkinson disease and dementia with Lewy bodies. Annals of Neurology, 81 (6), 898-903. doi:10.1002/ana.24937 Peer Reviewed verified by ORBi |
 | Blauwendraat, C., Faghri, F., Pihlstrom, L., Geiger, J. T., Elbaz, A., Lesage, S., May, P., Aude, N., Abramzon, Y., Murphy, N. A., Gibbs, J. R., Ryten, M., Ferrari, R., Bras, J., Guerreiro, R., Williams, J., Sims, R., Lubbe, S., Hernandez, D. G., ... Scholz, S. W. (2017). NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2017.05.009 Peer Reviewed verified by ORBi |
 | Krüger, R., Klucken, J., Weiss, D., Tonges, L., Kolber, P. L., Unterecker, S., Lorrain, M., Baas, H., Muller, T., & Riederer, P. (24 March 2017). Classification of advanced stages of Parkinson's disease: translation into stratified treatments. Journal of Neural Transmission, 124 (124), 1015-1027. doi:10.1007/s00702-017-1707-x Peer Reviewed verified by ORBi |
 | Straniero, L., Rimoldi, V., Samarani, M., Goldwurm, S., Di Fonzo, A., Krüger, R., Deleidi, M., Aureli, M., Solda, G., Duga, S., & Asselta, R. (2017). The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p. Scientific Reports, 7 (1), 12702. doi:10.1038/s41598-017-12973-5 Peer Reviewed verified by ORBi |
 | Scholten, M., Klemt, J., Heilbronn, M., Plewnia, C., Bloem, B. R., Bunjes, F., Krüger, R., Gharabaghi, A., & Weiss, D. (2017). Effects of Subthalamic and Nigral Stimulation on Gait Kinematics in Parkinson's Disease. Frontiers in Neurology, 8, 543. doi:10.3389/fneur.2017.00543 Peer Reviewed verified by ORBi |
 | Wang, L., Heckman, M. G., Aasly, J. O., Annesi, G., Bozi, M., Chung, S. J., Clarke, C., Crosiers, D., Eckstein, G., Garraux, G., Hadjigeorgiou, G. M., Hattori, N., Jeon, B., Kim, Y. J., Kubo, M., Lesage, S., Lin, J. J., Lynch, T., Lichtner, P., ... Sharma, M. (January 2017). Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study. Neurobiology of Aging, 49, 217.e1-217.e4. doi:10.1016/j.neurobiolaging.2016.09.022 Peer Reviewed verified by ORBi |
 | Klionsky, D., & Krüger, R. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12 (1), 1-222. doi:10.1080/15548627.2015.1100356 Peer Reviewed verified by ORBi |
 | Casadei, N., Sood, P., Ulrich, T., Kieper, N., Helling, S., May, C., Glaab, E., Chen, J., Nuber, S., Marcus, K., Rapaport, D., Ott, T., Riess, O., Krüger, R., & Fitzgerald, J. (2016). Mitochondrial Defects and Neurodegeneration in Mice Overexpressing Wild Type or G399S Mutant HtrA2. Human Molecular Genetics, 25 (3), 459-71. doi:10.1093/hmg/ddv485 Peer Reviewed verified by ORBi |
 | Scholten, M., Klotz, R., Plewnia, C., Wachter, T., Mielke, C., Bloem, B. R., Braun, C., Ziemann, U., Govindan, R. B., Gharabaghi, A., Krüger, R., & Weiss, D. (2016). Neuromuscular correlates of subthalamic stimulation and upper limb freezing in Parkinson's disease. Clinical Neurophysiology. doi:10.1016/j.clinph.2015.02.012 Peer Reviewed verified by ORBi |
 | Scholten, M., Govindan, R. B., Braun, C., Bloem, B. R., Plewnia, C., Krüger, R., Gharabaghi, A., & Weiss, D. (2016). Cortical correlates of susceptibility to upper limb freezing in Parkinson's disease. Clinical Neurophysiology, 127 (6), 2386-93. doi:10.1016/j.clinph.2016.01.028 Peer Reviewed verified by ORBi |
 | Heinzel, S., Roeben, B., Ben-Shlomo, Y., Lerche, S., Alves, G., Barone, P., Behnke, S., Berendse, H. W., Bloem, B. R., Burn, D., Dodel, R., Grosset, D. G., Hu, M., Kasten, M., Krüger, R., Moccia, M., Mollenhauer, B., Oertel, W., Suenkel, U., ... Berg, D. (2016). Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned. Frontiers in Aging Neuroscience, 8, 147. doi:10.3389/fnagi.2016.00147 Peer Reviewed verified by ORBi |
 | Lerche, S., Heinzel, S., Alves, G. W., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H., Bloem, B. R., Burn, D., Dodel, R., Grosset, D. G., Hipp, G., Hu, M. T., Kasten, M., Krüger, R., Liepelt-Scarfone, I., Maetzler, W., Moccia, M., Mollenhauer, B., ... Berg, D. (2016). Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies. Frontiers in Aging Neuroscience, 8, 121. doi:10.3389/fnagi.2016.00121 Peer Reviewed verified by ORBi |
 | Maetzler, W., Krüger, R., Muller, T., Oertel, W., Urban, P., Warnecke, T., & Klucken, J. (2016). Tragbare und aktiv vom Parkinson-Patienten genutzte Technologie im hauslichen Umfeld: Was bringt die Zukunft? Fortschritte der Neurologie-Psychiatrie, 84 Suppl 1, 48-51. doi:10.1055/s-0042-102786 Peer Reviewed verified by ORBi |
 | Wüst, R., Maurer, B., Hauser, K., Woitalla, D., Sharma, M., & Krüger, R. (2016). Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson's disease. Neurobiology of Aging, 39, 217.e13 - 217.e15. doi:10.1016/j.neurobiolaging.2015.11.025 Peer Reviewed verified by ORBi |
 | Krüger, R., Hilker, R., Winkler, C., Lorrain, M., Hahne, M., Redecker, C., Lingor, P., & Jost, W. H. (2016). Advanced stages of PD: interventional therapies and related patient-centered care. Journal of Neural Transmission. doi:10.1007/s00702-015-1418-0 Peer Reviewed verified by ORBi |
 | Meiser, J., Delcambre, S., Wegner, A., Jäger, C., Ghelfi, J., Fouquier d'Hérouël, A., Dong, X., Weindl, D., Stautner, C., Nonnenmacher, Y., Michelucci, A., Popp, O., Giesert, F., Schildknecht, S., Kraemer, L., Schneider, J. G., Woitalla, D., Wurst, W., Skupin, A., ... Hiller, K. (2016). Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism. Neurobiology of Disease, 89, 112-125. doi:10.1016/j.nbd.2016.01.019 Peer Reviewed verified by ORBi |
 | Dams, J., Balzer-Geldsetzer, M., Siebert, U., Deuschl, G., Schuepbach, W. M., Krack, P., Timmermann, L., Schnitzler, A., Reese, J.-P., Dodel, R., Krüger, R., & EARLYSTIM-investigators. (2016). Cost-Effectiveness of Neurostimulation in Parkinson's Disease With Early Motor Complications. Movement Disorders, 31 (8), 1183-1191. doi:10.1002/mds.26740 Peer Reviewed verified by ORBi |
 | Weiss, D., Herrmann, S., Wang, L., Schulte, C., Brockmann, K., Plewnia, C., Gasser, T., Sharma, M., Gharabaghi, A., & Krüger, R. (2016). Alpha-synuclein gene variants may predict neurostimulation outcome. Movement Disorders. doi:10.1002/mds.26558 Peer Reviewed verified by ORBi |
 | Weiss, D., Klotz, R., Govindan, R. B., Scholten, M., Naros, G., Ramos-Murguialday, A., Bunjes, F., Meisner, C., Plewnia, C., Krüger, R., & Gharabaghi, A. (2015). Subthalamic stimulation modulates cortical motor network activity and synchronization in Parkinson's disease. Brain: a Journal of Neurology, 138 (Pt 3), 679-93. doi:10.1093/brain/awu380 Peer Reviewed verified by ORBi |
 | Bruggemann, N., Kuhn, A., Schneider, S. A., Kamm, C., Wolters, A., Krause, P., Moro, E., Steigerwald, F., Wittstock, M., Tronnier, V., Lozano, A. M., Hamani, C., Poon, Y. Y., Zittel, S., Wachter, T., Deuschl, G., Krüger, R., Kupsch, A., Munchau, A., ... Klein, C. (2015). Short- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia. Neurology, 84 (9), 895-903. doi:10.1212/WNL.0000000000001312 Peer Reviewed verified by ORBi |
 | Chen, J., Shinde, S., Koch, M.-H., Eisenacher, M., Galozzi, S., Lerari, T., Barkovits, K., Subedi, P., Krüger, R., Kuhlmann, K., Sellergren, B., Helling, S., & Marcus, K. (2015). Low-bias phosphopeptide enrichment from scarce samples using plastic antibodies. Scientific Reports, 5, 11438. doi:10.1038/srep11438 Peer Reviewed verified by ORBi |
 | Nieratschker, V., Kiefer, C., Giel, K., Krüger, R., & Plewnia, C. (2015). The COMT Val/Met polymorphism modulates effects of tDCS on response inhibition. Brain stimulation, 8 (2), 283-288. doi:10.1016/j.brs.2014.11.009 Peer reviewed |
 | Maus, F., Sakry, D., Biname, F., Karram, K., Rajalingam, K., Watts, C., Heywood, R., Krüger, R., Stegmuller, J., Werner, H. B., Nave, K. A., Kramer-Albers, E. M., & Trotter, J. (2015). The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2. PLoS ONE, 10 (9), 0137311. doi:10.1371/journal.pone.0137311 Peer Reviewed verified by ORBi |
 | Wang, L., Aasly, J. O., Annesi, G., Bardien, S., Bozi, M., Brice, A., Carr, J., Chung, S. J., Clarke, C., Crosiers, D., Deutschlander, A., Eckstein, G., Farrer, M. J., Goldwurm, S., Garraux, G., Hadjigeorgiou, G. M., Hicks, A. A., Hattori, N., Klein, C., ... Sharma, M. (2015). Large-scale assessment of polyglutamine repeat expansions in Parkinson disease. Neurology, 85 (15), 1283-92. doi:10.1212/WNL.0000000000002016 Peer Reviewed verified by ORBi |
 | Lerche, S., Liepelt-Scarfone, I., Alves, G., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H., Burn, D., Dodel, R., Grosset, D., Heinzel, S., Hu, M., Kasten, M., Krüger, R., Maetzler, W., Moccia, M., Mollenhauer, B., Oertel, W., Roeben, B., ... Berg, D. (2015). Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease - Report of the JPND Working Group BioLoC-PD. Neuroepidemiology, 45 (4), 282-297. doi:10.1159/000439221 Peer Reviewed verified by ORBi |
 | Odin, P., Chaudhuri, K. R., Slevin, J. T., Volkmann, J., Dietrichs, E., Martinez-Martin, P., Krauss, J. K., Henriksen, T., Katzenschlager, R., Antonini, A., Rascol, O., Poewe, W., Krüger, R., & National Steering Committees. (2015). Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2015.07.020 Peer Reviewed verified by ORBi |
 | Puschmann, A., Brighina, L., Markopoulou, K., Aasly, J., Chung, S. J., Frigerio, R., Hadjigeorgiou, G., Koks, S., Krüger, R., Siuda, J., Wider, C., Zesiewicz, T. A., & Maraganore, D. M. (2015). Clinically meaningful parameters of progression and long-term outcome of Parkinson disease: An international consensus statement. Parkinsonism and Related Disorders, 21 (7), 675-682. doi:10.1016/j.parkreldis.2015.04.029 Peer Reviewed verified by ORBi |
 | Lew, M. F., Slevin, J. T., Krüger, R., Martinez, C., Chatamra, K., Dubow, J. S., Robieson, W. Z., Benesh, J. A., & Fung, V. S. (2015). Initiation and dose optimization for levodopa-carbidopa intestinal gel: Insights from phase 3 clinical trials. Parkinsonism and Related Disorders, 21 (7), 742-748. doi:10.1016/j.parkreldis.2015.04.022 Peer Reviewed verified by ORBi |
 | Ortega-Cubero, S., Lorenzo-Betancor, O., Lorenzo, E., Agundez, J. A., Jimenez-Jimenez, F. J., Ross, O. A., Wurster, I., Mielke, C., Lin, J. J., Coria, F., Clarimon, J., Ezquerra, M., Brighina, L., Annesi, G., Alonso-Navarro, H., Garcia-Martin, E., Gironell, A., Marti, M. J., Yueh, K. C., ... Pastor, P. (2015). TREM2 R47H variant and risk of essential tremor: a cross-sectional international multicenter study. Parkinsonism and Related Disorders, 21 (3), 306-309. doi:10.1016/j.parkreldis.2014.12.010 Peer Reviewed verified by ORBi |
 | Weiss, D., Mielke, C., Wachter, T., Bender, B., Liscic, R. M., Scholten, M., Naros, G., Plewnia, C., Gharabaghi, A., & Krüger, R. (2015). Long-term outcome of deep brain stimulation in fragile X-associated tremor/ataxia syndrome. Parkinsonism and Related Disorders, 21 (3), 310-313. doi:10.1016/j.parkreldis.2014.12.015 Peer Reviewed verified by ORBi |
 | Jonmohamadi, Y., Poudel, Innes, C., Weiss, D., Krüger, R., & Jones, R. (November 2014). Comparison of beamformers for EEG source signal reconstruction. Biomedical Signal Processing and Control, 14, 175-188. doi:10.1016/j.bspc.2014.07.014 Peer Reviewed verified by ORBi |
 | Weiss, D., Lam, J. M., Breit, S., Gharabaghi, A., Krüger, R., Luft, A. R., & Wachter, T. (2014). The subthalamic nucleus modulates the early phase of probabilistic classification learning. Experimental Brain Research, 232 (7), 2255-62. doi:10.1007/s00221-014-3916-y Peer Reviewed verified by ORBi |
 | Sharma, M., Wenning, G., & Krüger, R. (2014). Mutant COQ2 in multiple-system atrophy. The New England journal of medicine, 371 (1), 80-1. doi:10.1056/NEJMc1311763 Peer reviewed |
 | Casadei, N., Pohler, A.-M., Tomas-Zapico, C., Torres-Peraza, J., Schwedhelm, I., Witz, A., Zamolo, I., De Heer, R., Spruijt, B., Noldus, L. P. J. J., Klucken, J., Lucas, J. J., Kahle, P. J., Krüger, R., Riess, O., & Nuber, S. (2014). Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice. Human Molecular Genetics, 23 (3), 767-81. doi:10.1093/hmg/ddt467 Peer Reviewed verified by ORBi |
 | Theuns, J., Verstraeten, A., Sleegers, K., Wauters, E., Gijselinck, I., Smolders, S., Crosiers, D., Corsmit, E., Elinck, E., Sharma, M., Krüger, R., Lesage, S., Brice, A., Chung, S. J., Kim, M.-J., Kim, Y. J., Ross, O. A., Wszolek, Z. K., Rogaeva, E., ... Van Broeckhoven, C. (2014). Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease. Neurology. doi:10.1212/WNL.0000000000001012 Peer Reviewed verified by ORBi |
 | Sharma, M., Krüger, R., & Gasser, T. (2014). From genome-wide association studies to next-generation sequencing: lessons from the past and planning for the future. JAMA Neurology, 71 (1), 5-6. doi:10.1001/jamaneurol.2013.3682 Peer Reviewed verified by ORBi |
 | Huttenlocher, J., Krüger, R., Capetian, P., Lohmann, K., Brockmann, K., Csoti, I., Klein, C., Berg, D., Gasser, T., Bonin, M., Riess, O., & Bauer, P. (2014). EIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts. Journal of Medical Genetics, 0, 1-5. doi:10.1136/jmedgenet-2014-102570 Peer Reviewed verified by ORBi |
 | Burbulla, L. F., Fitzgerald, J. C., Stegen, K., Westermeier, J., Thost, A.-K., Kato, H., Mokranjac, D., Sauerwald, J., Martins, L., Woitalla, D., Rapaport, D., Riess, O., Proikas-Cezanne, T., Rasse, T. M., & Krüger, R. (2014). Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1. Cell Death and Disease, 5, 1180. doi:10.1038/cddis.2014.103 Peer Reviewed verified by ORBi |
 | Heckman, M. G., Elbaz, A., Soto-Ortolaza, A. I., Serie, D. J., Aasly, J. O., Annesi, G., Auburger, G., Bacon, J. A., Boczarska-Jedynak, M., Bozi, M., Brighina, L., Chartier-Harlin, M.-C., Dardiotis, E., Destee, A., Ferrarese, C., Ferraris, A., Fiske, B., Gispert, S., Hadjigeorgiou, G. M., ... Ross, O. A. (2014). Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants. Neurobiology of Aging, 35 (1), 266.e5-14. doi:10.1016/j.neurobiolaging.2013.07.013 Peer Reviewed verified by ORBi |
 | Chung, S. J., Biernacka, J. M., Armasu, S. M., Anderson, K., Frigerio, R., Aasly, J. O., Annesi, G., Bentivoglio, A. R., Brighina, L., Chartier-Harlin, M.-C., Goldwurm, S., Hadjigeorgiou, G., Jasinska-Myga, B., Jeon, B. S., Kim, Y. J., Krüger, R., Lesage, S., Markopoulou, K., Mellick, G., ... Maraganore, D. M. (2014). Alpha-synuclein repeat variants and survival in Parkinson's disease. Movement Disorders. doi:10.1002/mds.25841 Peer Reviewed verified by ORBi |
 | Antony, P., Diederich, N., Krüger, R., & Balling, R. (2013). The hallmarks of Parkinson's disease. FEBS Journal, 13. doi:10.1111/febs.12335 Peer reviewed |
 | Zhu, J.-Y., Vereshchagina, N., Sreekumar, V., Burbulla, L. F., Costa, A. C., Daub, K. J., Woitalla, D., Martins, L., Krüger, R., & Rasse, T. M. (2013). Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson's disease model. PLoS ONE, 8 (12), 83714. doi:10.1371/journal.pone.0083714 Peer Reviewed verified by ORBi |
 | Weiss, D., Walach, M., Meisner, C., Fritz, M., Scholten, M., Breit, S., Plewnia, C., Bender, B., Gharabaghi, A., Wachter, T., & Krüger, R. (2013). Nigral stimulation for resistant axial motor impairment in Parkinson's disease? A randomized controlled trial. Brain: a Journal of Neurology, 136 (Pt 7), 2098-108. doi:10.1093/brain/awt122 Peer Reviewed verified by ORBi |
 | Schuepbach, W. M. M., Rau, J., Knudsen, K., Volkmann, J., Krack, P., Timmermann, L., Halbig, T. D., Hesekamp, H., Navarro, S. M., Meier, N., Falk, D., Mehdorn, M., Paschen, S., Maarouf, M., Barbe, M. T., Fink, G. R., Kupsch, A., Gruber, D., Schneider, G.-H., ... Deuschl, G. (2013). Neurostimulation for Parkinson's disease with early motor complications. The New England journal of medicine, 368 (7), 610-22. doi:10.1056/NEJMoa1205158 Peer reviewed |
 | Grau, T., Burbulla, L. F., Engl, G., Delettre, C., Delprat, B., Oexle, K., Leo-Kottler, B., Roscioli, T., Krüger, R., Rapaport, D., Wissinger, B., & Schimpf-Linzenbold, S. (2013). A novel heterozygous OPA3 mutation located in the mitochondrial target sequence results in altered steady-state levels and fragmented mitochondrial network. Journal of Medical Genetics, 50 (12), 848-58. doi:10.1136/jmedgenet-2013-101774 Peer Reviewed verified by ORBi |
 | Riess, A., Rossier, E., Krüger, R., Dufke, A., Beck-Woedl, S., Horber, V., Alber, M., Glaser, D., Riess, O., & Tzschach, A. (2013). Novel SLC9A6 mutations in two families with Christianson syndrome. Clinical Genetics, 83 (6), 596-7. doi:10.1111/j.1399-0004.2012.01948.x Peer Reviewed verified by ORBi |
 | Karle, K. N., Biskup, S., Schule, R., Schweitzer, K. J., Krüger, R., Bauer, P., Bender, B., Nagele, T., & Schols, L. (2013). De novo mutations in hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS). Neurology, 81 (23), 2039-44. doi:10.1212/01.wnl.0000436945.01023.ac Peer Reviewed verified by ORBi |
 | Reinhardt, P., Schmid, B., Burbulla, L. F., Schondorf, D. C., Wagner, L., Glatza, M., Hoing, S., Hargus, G., Heck, S. A., Dhingra, A., Wu, G., Muller, S., Brockmann, K., Kluba, T., Maisel, M., Krüger, R., Berg, D., Tsytsyura, Y., Thiel, C. S., ... Sterneckert, J. (2013). Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell Stem Cell, 12 (3), 354-67. doi:10.1016/j.stem.2013.01.008 Peer Reviewed verified by ORBi |
 | Plewnia, C., Zwissler, B., Langst, I., Maurer, B., Giel, K., & Krüger, R. (2013). Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism. Cortex: A Journal Devoted to the Study of the Nervous System and Behavior, 49 (7), 1801-7. doi:10.1016/j.cortex.2012.11.002 Peer Reviewed verified by ORBi |
 | Heckman, M. G., Soto-Ortolaza, A. I., Aasly, J. O., Abahuni, N., Annesi, G., Bacon, J. A., Bardien, S., Bozi, M., Brice, A., Brighina, L., Carr, J., Chartier-Harlin, M.-C., Dardiotis, E., Dickson, D. W., Diehl, N. N., Elbaz, A., Ferrarese, C., Fiske, B., Gibson, J. M., ... Ross, O. A. (2013). Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium. Movement Disorders, 28 (12), 1740-4. doi:10.1002/mds.25600 Peer Reviewed verified by ORBi |
 | Sharma, M., Ioannidis, J. P. A., Aasly, J. O., Annesi, G., Brice, A., Van Broeckhoven, C., Bertram, L., Bozi, M., Crosiers, D., Clarke, C., Facheris, M., Farrer, M., Garraux, G., Gispert, S., Auburger, G., Vilarino-Guell, C., Hadjigeorgiou, G. M., Hicks, A. A., Hattori, N., ... Krüger, R. (2012). Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology, 79 (7), 659-67. doi:10.1212/WNL.0b013e318264e353 Peer Reviewed verified by ORBi |
 | Weiss, D., Breit, S., Hoppe, J., Hauser, A.-K., Freudenstein, D., Krüger, R., Sauseng, P., Govindan, R. B., & Gerloff, C. (2012). Subthalamic nucleus stimulation restores the efferent cortical drive to muscle in parallel to functional motor improvement. The European journal of neuroscience, 35 (6), 896-908. doi:10.1111/j.1460-9568.2012.08014.x Peer reviewed |
 | Sharma, M., Ioannidis, J. P. A., Aasly, J. O., Annesi, G., Brice, A., Bertram, L., Bozi, M., Barcikowska, M., Crosiers, D., Clarke, C. E., Facheris, M. F., Farrer, M., Garraux, G., Gispert, S., Auburger, G., Vilarino-Guell, C., Hadjigeorgiou, G. M., Hicks, A. A., Hattori, N., ... Krüger, R. (2012). A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants. Journal of Medical Genetics, 49 (11), 721-6. doi:10.1136/jmedgenet-2012-101155 Peer Reviewed verified by ORBi |
 | Fitzgerald, J. C., Camprubi, M. D., Dunn, L., Wu, H.-C., Ip, N. Y., Krüger, R., Martins, L., Wood, N. W., & Plun-Favreau, H. (2012). Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function. Cell Death and Differentiation, 19 (2), 257-66. doi:10.1038/cdd.2011.90 Peer Reviewed verified by ORBi |
 | Weiss, D., Brockmann, K., Srulijes, K., Meisner, C., Klotz, R., Reinbold, S., Hauser, A.-K., Schulte, C., Berg, D., Gasser, T., Plewnia, C., Gharabaghi, A., Breit, S., Wachter, T., & Krüger, R. (2012). Long-term follow-up of subthalamic nucleus stimulation in glucocerebrosidase-associated Parkinson's disease. Journal of Neurology, 259 (9), 1970-2. doi:10.1007/s00415-012-6469-7 Peer Reviewed verified by ORBi |
 | Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., ... Zuckerbraun, B. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8 (4), 445-544. doi:10.4161/auto.19496 Peer Reviewed verified by ORBi |
 | Burbulla, L. F., & Krüger, R. (2012). The use of primary human fibroblasts for monitoring mitochondrial phenotypes in the field of Parkinson's disease. Journal of Visualized Experiments, (68). doi:10.3791/4228 Peer Reviewed verified by ORBi |
 | Sharma, M., Krüger, R., & Gasser, T. (2012). LRRK2: Understanding the role of common and rare variants in Parkinson's disease. Movement Disorders, 27 (4), 475. doi:10.1002/mds.24937 Peer Reviewed verified by ORBi |
 | Gispert, S., Kurz, A., Waibel, S., Bauer, P., Liepelt, I., Geisen, C., Gitler, A. D., Becker, T., Weber, M., Berg, D., Andersen, P. M., Krüger, R., Riess, O., Ludolph, A. C., & Auburger, G. (2012). The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect. Neurobiology of Disease, 45 (1), 356-61. doi:10.1016/j.nbd.2011.08.021 Peer Reviewed verified by ORBi |
 | Lengerer, S., Kipping, J., Rommel, N., Weiss, D., Breit, S., Gasser, T., Plewnia, C., Krüger, R., & Wachter, T. (2012). Deep-brain-stimulation does not impair deglutition in Parkinson's disease. Parkinsonism and Related Disorders, 18 (7), 847-53. doi:10.1016/j.parkreldis.2012.04.014 Peer Reviewed verified by ORBi |
 | Weiss, D., Wachter, T., Meisner, C., Fritz, M., Gharabaghi, A., Plewnia, C., Breit, S., & Krüger, R. (2011). Combined STN/SNr-DBS for the treatment of refractory gait disturbances in Parkinson's disease: study protocol for a randomized controlled trial. Trials, 12, 222. doi:10.1186/1745-6215-12-222 Peer Reviewed verified by ORBi |
 | Bruck, C., Wildgruber, D., Kreifelts, B., Krüger, R., & Wachter, T. (2011). Effects of subthalamic nucleus stimulation on emotional prosody comprehension in Parkinson's disease. PLoS ONE, 6 (4), 19140. doi:10.1371/journal.pone.0019140 Peer Reviewed verified by ORBi |
 | Burbulla, L. F., & Krüger, R. (2011). Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease. Journal of the Neurological Sciences, 306 (1-2), 1-8. doi:10.1016/j.jns.2011.04.005 Peer Reviewed verified by ORBi |
 | Elbaz, A., Ross, O. A., Ioannidis, J. P. A., Soto-Ortolaza, A. I., Moisan, F., Aasly, J., Annesi, G., Bozi, M., Brighina, L., Chartier-Harlin, M.-C., Destee, A., Ferrarese, C., Ferraris, A., Gibson, J. M., Gispert, S., Hadjigeorgiou, G. M., Jasinska-Myga, B., Klein, C., Krüger, R., ... Farrer, M. J. (2011). Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. Annals of Neurology, 69 (5), 778-92. doi:10.1002/ana.22321 Peer Reviewed verified by ORBi |
 | Weiss, D., Breit, S., Wachter, T., Plewnia, C., Gharabaghi, A., & Krüger, R. (2011). Combined stimulation of the substantia nigra pars reticulata and the subthalamic nucleus is effective in hypokinetic gait disturbance in Parkinson's disease. Journal of Neurology, 258 (6), 1183-5. doi:10.1007/s00415-011-5906-3 Peer Reviewed verified by ORBi |
 | Weiss, D., Brockmann, K., Nagele, T., Gasser, T., & Krüger, R. (2011). Rapid emergence of temporal and pulvinar lesions in MELAS mimicking Creutzfeldt-Jakob disease. Neurology, 77 (9), 914. doi:10.1212/WNL.0b013e31822c6275 Peer Reviewed verified by ORBi |
 | Wachter, T., Engeholm, M., Bisdas, S., Schittenhelm, J., Gasser, T., & Krüger, R. (2011). Slowly progressive Parkinson syndrome due to thalamic butterfly astrocytoma. Neurology, 77 (4), 404-5. doi:10.1212/WNL.0b013e3182267bc4 Peer Reviewed verified by ORBi |
 | Rzesnitzek, L., Wachter, T., Krüger, R., Gharabaghi, A., & Plewnia, C. (2011). Suppression of extrapyramidal side effects of doxepin by thalamic deep brain stimulation for Tourette syndrome. Neurology, 77 (18), 1708-9. doi:10.1212/WNL.0b013e318236485f Peer Reviewed verified by ORBi |
 | Ross, O. A., Soto-Ortolaza, A. I., Heckman, M. G., Aasly, J. O., Abahuni, N., Annesi, G., Bacon, J. A., Bardien, S., Bozi, M., Brice, A., Brighina, L., Van Broeckhoven, C., Carr, J., Chartier-Harlin, M.-C., Dardiotis, E., Dickson, D. W., Diehl, N. N., Elbaz, A., Ferrarese, C., ... Farrer, M. J. (2011). Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study. Lancet Neurology, 10 (10), 898-908. doi:10.1016/S1474-4422(11)70175-2 Peer Reviewed verified by ORBi |
 | Weiss, D., Govindan, R. B., Rilk, A., Wachter, T., Breit, S., Zizlsperger, L., Haarmeier, T., Plewnia, C., Krüger, R., & Gharabaghi, A. (2011). Central oscillators in a patient with neuropathic tremor: evidence from intraoperative local field potential recordings. Movement Disorders, 26 (2), 323-7. doi:10.1002/mds.23374 Peer Reviewed verified by ORBi |
 | Nuber, S., Petrasch-Parwez, E., Arias-Carrion, O., Koch, L., Kohl, Z., Schneider, J., Calaminus, C., Dermietzel, R., Samarina, A., Boy, J., Nguyen, H. P., Teismann, P., Velavan, T. P., Kahle, P. J., von Horsten, S., Fendt, M., Krüger, R., & Riess, O. (2011). Olfactory neuron-specific expression of A30P alpha-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages. Neurobiology of Disease, 44 (2), 192-204. doi:10.1016/j.nbd.2011.06.017 Peer Reviewed verified by ORBi |
 | Krüger, R., Sharma, M., Riess, O., Gasser, T., Van Broeckhoven, C., Theuns, J., Aasly, J., Annesi, G., Bentivoglio, A. R., Brice, A., Djarmati, A., Elbaz, A., Farrer, M., Ferrarese, C., Gibson, J. M., Hadjigeorgiou, G. M., Hattori, N., Ioannidis, J. P. A., Jasinska-Myga, B., ... Maraganore, D. M. (2011). A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Neurobiology of Aging, 32 (3), 548.e9-18. doi:10.1016/j.neurobiolaging.2009.11.021 Peer Reviewed verified by ORBi |
 | Sharma, M., Maraganore, D. M., Ioannidis, J. P. A., Riess, O., Aasly, J. O., Annesi, G., Abahuni, N., Bentivoglio, A. R., Brice, A., Van Broeckhoven, C., Chartier-Harlin, M.-C., Destee, A., Djarmati, A., Elbaz, A., Farrer, M., Ferrarese, C., Gibson, J. M., Gispert, S., Hattori, N., ... Krüger, R. (2011). Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease. Neurobiology of Aging, 32 (11), 2108.e1-5. doi:10.1016/j.neurobiolaging.2011.05.024 Peer Reviewed verified by ORBi |
 | Krebiehl, G., Ruckerbauer, S., Burbulla, L. F., Kieper, N., Maurer, B., Waak, J., Wolburg, H., Gizatullina, Z., Gellerich, F. N., Woitalla, D., Riess, O., Kahle, P. J., Proikas-Cezanne, T., & Krüger, R. (2010). Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PLoS ONE, 5 (2), 9367. doi:10.1371/journal.pone.0009367 Peer Reviewed verified by ORBi |
 | Burbulla, L. F., Krebiehl, G., & Krüger, R. (2010). Balance is the challenge--the impact of mitochondrial dynamics in Parkinson's disease. European Journal of Clinical Investigation, 40 (11), 1048-60. doi:10.1111/j.1365-2362.2010.02354.x Peer Reviewed verified by ORBi |
 | Burbulla, L. F., Schelling, C., Kato, H., Rapaport, D., Woitalla, D., Schiesling, C., Schulte, C., Sharma, M., Illig, T., Bauer, P., Jung, S., Nordheim, A., Schols, L., Riess, O., & Krüger, R. (2010). Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis. Human Molecular Genetics, 19 (22), 4437-52. doi:10.1093/hmg/ddq370 Peer Reviewed verified by ORBi |
 | Seidel, K., Schols, L., Nuber, S., Petrasch-Parwez, E., Gierga, K., Wszolek, Z., Dickson, D., Gai, W. P., Bornemann, A., Riess, O., Rami, A., Den Dunnen, W. F. A., Deller, T., Rub, U., & Krüger, R. (2010). First appraisal of brain pathology owing to A30P mutant alpha-synuclein. Annals of Neurology, 67 (5), 684-9. doi:10.1002/ana.21966 Peer Reviewed verified by ORBi |
 | Nuber, S., Franck, T., Wolburg, H., Schumann, U., Casadei, N., Fischer, K., Calaminus, C., Pichler, B. J., Chanarat, S., Teismann, P., Schulz, J. B., Luft, A. R., Tomiuk, J., Wilbertz, J., Bornemann, A., Krüger, R., & Riess, O. (2010). Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice. Neurogenetics, 11 (1), 107-20. doi:10.1007/s10048-009-0212-2 Peer Reviewed verified by ORBi |
 | Soehn, A. S., Franck, T., Biskup, S., Giaime, E., Melle, C., Rott, R., Cebo, D., Kalbacher, H., Ott, E., Pahnke, J., Meitinger, T., Krüger, R., Gasser, T., Berg, D., von Eggeling, F., Engelender, S., da Costa, C. A., & Riess, O. (2010). Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease. Neurogenetics, 11 (2), 203-15. doi:10.1007/s10048-009-0215-z Peer Reviewed verified by ORBi |
 | Weiss, D., Wachter, T., Breit, S., Jacob, S. N., Pomper, J. K., Asmus, F., Valls-Sole, J., Plewnia, C., Gasser, T., Gharabaghi, A., & Krüger, R. (2010). Involuntary eyelid closure after STN-DBS: evidence for different pathophysiological entities. Journal of Neurology, Neurosurgery and Psychiatry, 81 (9), 1002-7. doi:10.1136/jnnp.2009.196691 Peer Reviewed verified by ORBi |
 | Breit, S., Wachter, T., Schmid-Bielenberg, D., Weiss, D., Leitner, P., Nagele, T., Freudenstein, D., Gasser, T., & Krüger, R. (2010). Effective long-term subthalamic stimulation in PARK8 positive Parkinson's disease. Journal of Neurology, 257 (7), 1205-7. doi:10.1007/s00415-010-5493-8 Peer Reviewed verified by ORBi |
 | Synofzik, M., Weiss, D., Erharhaghen, J., Krüger, R., & Schols, L. (2010). Severe orthostatic dysregulation associated with Wolfram syndrome. Journal of Neurology, 257 (10), 1751-3. doi:10.1007/s00415-010-5593-5 Peer Reviewed verified by ORBi |
 | Kieper, N., Holmstrom, K. M., Ciceri, D., Fiesel, F. C., Wolburg, H., Ziviani, E., Whitworth, A. J., Martins, L., Kahle, P. J., & Krüger, R. (2010). Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1. Experimental Cell Research, 316 (7), 1213-24. doi:10.1016/j.yexcr.2010.01.005 Peer Reviewed verified by ORBi |
 | Synofzik, M., Schule, R., Schulte, C., Krüger, R., Lindig, T., Schols, L., & Asmus, F. (2010). Complex hyperkinetic movement disorders associated with POLG mutations. Movement Disorders, 25 (14), 2472-5. doi:10.1002/mds.23307 Peer Reviewed verified by ORBi |
 | Breit, S., Wachter, T., Schols, L., Gasser, T., Nagele, T., Freudenstein, D., & Krüger, R. (2009). Effective thalamic deep brain stimulation for neuropathic tremor in a patient with severe demyelinating neuropathy. Journal of Neurology, Neurosurgery and Psychiatry, 80 (2), 235-6. doi:10.1136/jnnp.2008.145656 Peer Reviewed verified by ORBi |
 | Elstner, M., Morris, C. M., Heim, K., Lichtner, P., Bender, A., Mehta, D., Schulte, C., Sharma, M., Hudson, G., Goldwurm, S., Giovanetti, A., Zeviani, M., Burn, D. J., McKeith, I. G., Perry, R. H., Jaros, E., Krüger, R., Wichmann, H.-E., Schreiber, S., ... Turnbull, D. M. (2009). Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene. Annals of Neurology, 66 (6), 792-8. doi:10.1002/ana.21780 Peer Reviewed verified by ORBi |
 | Simon-Sanchez, J., Schulte, C., Bras, J. M., Sharma, M., Gibbs, J. R., Berg, D., Paisan-Ruiz, C., Lichtner, P., Scholz, S. W., Hernandez, D. G., Krüger, R., Federoff, M., Klein, C., Goate, A., Perlmutter, J., Bonin, M., Nalls, M. A., Illig, T., Gieger, C., ... Gasser, T. (2009). Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nature Genetics, 41 (12), 1308-12. doi:10.1038/ng.487 Peer Reviewed verified by ORBi |
 | Wachter, T., Weiss, D., Breit, S., Gasser, T., Krüger, R., & Gharabaghi, A. (2009). Severe muscular fasciculations as an uncommon side-effect due to microdefect of an extension wire in deep brain stimulation. Movement Disorders, 24 (14), 2161-2. doi:10.1002/mds.22725 Peer Reviewed verified by ORBi |
 | Sharma, M., Lichtner, P., Krüger, R., Berg, D., Schulte, C., Illig, T., Riess, O., & Gasser, T. (2009). Further delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson's disease. Neurobiology of Aging, 30 (10), 1706-9. doi:10.1016/j.neurobiolaging.2007.12.016 Peer Reviewed verified by ORBi |
Schiesling, C., Kieper, N., Seidel, K., & Krüger, R. (2008). Review: Familial Parkinson's disease--genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease. Neuropathology and Applied Neurobiology, 34 (3), 255-71. doi:10.1111/j.1365-2990.2008.00952.x Peer Reviewed verified by ORBi |
Radke, S., Chander, H., Schafer, P., Meiss, G., Krüger, R., Schulz, J. B., & Germain, D. (2008). Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi. The Journal of biological chemistry, 283 (19), 12681-5. doi:10.1074/jbc.C800036200 Peer reviewed |
Krüger, R. (2008). LRRK2 in Parkinson's disease - drawing the curtain of penetrance: a commentary. BMC Medicine, 6, 33. doi:10.1186/1741-7015-6-33 Peer Reviewed verified by ORBi |
Plewnia, C., Schober, F., Rilk, A., Buchkremer, G., Reimold, M., Wachter, T., Breit, S., Weiss, D., Krüger, R., & Freudenstein, D. (2008). Sustained improvement of obsessive-compulsive disorder by deep brain stimulation in a woman with residual schizophrenia. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 11 (8), 1181-3. doi:10.1017/S1461145708009188 Peer reviewed |
Kamm, C., Fogel, W., Wachter, T., Schweitzer, K., Berg, D., Krüger, R., Freudenstein, D., & Gasser, T. (2008). Novel ATP1A3 mutation in a sporadic RDP patient with minimal benefit from deep brain stimulation. Neurology, 70 (16 Pt 2), 1501-3. doi:10.1212/01.wnl.0000310431.41036.e0 Peer Reviewed verified by ORBi |
Tabatabai, G., Schober, W., Ernemann, U., Weller, M., & Krüger, R. (2008). Vertebral artery dissection presenting with ispilateral acute C5 and C6 sensorimotor radiculopathy: A case report. Cases Journal, 1 (1), 139. doi:10.1186/1757-1626-1-139 Peer Reviewed verified by ORBi |
Bonin, M., Marx, F. P., Kautzmann, S., Riess, O., & Krüger, R. (2008). Microarray expression analysis reveals genetic pathways implicated in C621 synphilin-1-mediated toxicity. Journal of Neural Transmission, 115 (7), 941-58. doi:10.1007/s00702-008-0031-x Peer reviewed |
Wahl, C., Kautzmann, S., Krebiehl, G., Strauss, K., Woitalla, D., Muller, T., Bauer, P., Riess, O., & Krüger, R. (2008). A comprehensive genetic study of the proteasomal subunit S6 ATPase in German Parkinson's disease patients. Journal of Neural Transmission, 115 (8), 1141-8. doi:10.1007/s00702-008-0054-3 Peer reviewed |
Matzler, W., Nagele, T., Gasser, T., & Krüger, R. (2007). Acute parkinsonism with corresponding lesions in the basal ganglia after heroin abuse. Neurology, 68 (6), 414. doi:10.1212/01.wnl.0000250230.86581.ea Peer Reviewed verified by ORBi |
Exner, N., Treske, B., Paquet, D., Holmstrom, K., Schiesling, C., Gispert, S., Carballo-Carbajal, I., Berg, D., Hoepken, H.-H., Gasser, T., Krüger, R., Winklhofer, K. F., Vogel, F., Reichert, A. S., Auburger, G., Kahle, P. J., Schmid, B., & Haass, C. (2007). Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. The Journal of neuroscience : the official journal of the Society for Neuroscience, 27 (45), 12413-8. doi:10.1523/JNEUROSCI.0719-07.2007 Peer reviewed |
Schweitzer, K. J., Brussel, T., Leitner, P., Krüger, R., Bauer, P., Woitalla, D., Tomiuk, J., Gasser, T., & Berg, D. (2007). Transcranial ultrasound in different monogenetic subtypes of Parkinson's disease. Journal of Neurology, 254 (5), 613-6. doi:10.1007/s00415-006-0369-7 Peer Reviewed verified by ORBi |
 | Abahuni, N., Gispert, S., Bauer, P., Riess, O., Krüger, R., Becker, T., & Auburger, G. (2007). Mitochondrial translation initiation factor 3 gene polymorphism associated with Parkinson's disease. Neuroscience Letters, 414 (2), 126-9. doi:10.1016/j.neulet.2006.12.053 Peer reviewed |
Riess, O., Krüger, R., Hochstrasser, H., Soehn, A. S., Nuber, S., Franck, T., & Berg, D. (2006). Genetic causes of Parkinson's disease: extending the pathway. Journal of Neural Transmission. Supplementum, (70), 181-9. doi:10.1007/978-3-211-45295-0_29 Peer Reviewed verified by ORBi |
Maraganore, D. M., de Andrade, M., Elbaz, A., Farrer, M. J., Ioannidis, J. P., Krüger, R., Rocca, W. A., Schneider, N. K., Lesnick, T. G., Lincoln, S. J., Hulihan, M. M., Aasly, J. O., Ashizawa, T., Chartier-Harlin, M.-C., Checkoway, H., Ferrarese, C., Hadjigeorgiou, G., Hattori, N., Kawakami, H., ... Van Broeckhoven, C. (2006). Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. JAMA: Journal of the American Medical Association, 296 (6), 661-70. doi:10.1001/jama.296.6.661 Peer Reviewed verified by ORBi |
Elbaz, A., Nelson, L. M., Payami, H., Ioannidis, J. P. A., Fiske, B. K., Annesi, G., Carmine Belin, A., Factor, S. A., Ferrarese, C., Hadjigeorgiou, G. M., Higgins, D. S., Kawakami, H., Krüger, R., Marder, K. S., Mayeux, R. P., Mellick, G. D., Nutt, J. G., Ritz, B., Samii, A., ... Trikalinos, T. A. (2006). Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurology, 5 (11), 917-23. doi:10.1016/S1474-4422(06)70579-8 Peer reviewed |
Strauss, K. M., Martins, L., Plun-Favreau, H., Marx, F. P., Kautzmann, S., Berg, D., Gasser, T., Wszolek, Z., Muller, T., Bornemann, A., Wolburg, H., Downward, J., Riess, O., Schulz, J. B., & Krüger, R. (2005). Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Human molecular genetics, 14 (15), 2099-111. doi:10.1093/hmg/ddi215 Peer reviewed |
Hochstrasser, H., Tomiuk, J., Walter, U., Behnke, S., Spiegel, J., Krüger, R., Becker, G., Riess, O., & Berg, D. (2005). Functional relevance of ceruloplasmin mutations in Parkinson's disease. FASEB Journal, 19 (13), 1851-3. doi:10.1096/fj.04-3486fje Peer Reviewed verified by ORBi |
Hofer, A., Berg, D., Asmus, F., Niwar, M., Ransmayr, G., Riemenschneider, M., Bonelli, S.-B., Steffelbauer, M., Ceballos-Baumann, A., Haussermann, P., Behnke, S., Krüger, R., Prestel, J., Sharma, M., Zimprich, A., Riess, O., & Gasser, T. (2005). The role of alpha-synuclein gene multiplications in early-onset Parkinson's disease and dementia with Lewy bodies. Journal of Neural Transmission, 112 (9), 1249-54. doi:10.1007/s00702-004-0263-3 Peer reviewed |
Maraganore, D. M., Lesnick, T. G., Elbaz, A., Chartier-Harlin, M.-C., Gasser, T., Krüger, R., Hattori, N., Mellick, G. D., Quattrone, A., Satoh, J.-I., Toda, T., Wang, J., Ioannidis, J. P. A., de Andrade, M., & Rocca, W. A. (2004). UCHL1 is a Parkinson's disease susceptibility gene. Annals of neurology, 55 (4), 512-21. doi:10.1002/ana.20017 Peer reviewed |
Glass, A. S., Huynh, D. P., Franck, T., Woitalla, D., Muller, T., Pulst, S. M., Berg, D., Krüger, R., & Riess, O. (2004). Screening for mutations in synaptotagmin XI in Parkinson's disease. Journal of Neural Transmission. Supplementum, (68), 21-8. doi:10.1007/978-3-7091-0579-5_3 Peer Reviewed verified by ORBi |
Krüger, R. (2004). Genes in familial parkinsonism and their role in sporadic Parkinson's disease. Journal of Neurology, 251 Suppl 6, 2-6. doi:10.1007/s00415-004-1602-x Peer Reviewed verified by ORBi |
Storch, A., Hofer, A., Krüger, R., Schulz, J. B., Winkler, J., & Gerlach, M. (2004). New developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications. Journal of Neurology, 251 Suppl 6, 33-8. doi:10.1007/s00415-004-1608-4 Peer Reviewed verified by ORBi |
Hering, R., Petrovic, S., Mietz, E.-M., Holzmann, C., Berg, D., Bauer, P., Woitalla, D., Muller, T., Berger, K., Krüger, R., & Riess, O. (2004). Extended mutation analysis and association studies of Nurr1 (NR4A2) in Parkinson disease. Neurology, 62 (7), 1231-2. doi:10.1212/01.WNL.0000118285.18383.90 Peer Reviewed verified by ORBi |
Hering, R., Strauss, K. M., Tao, X., Bauer, A., Woitalla, D., Mietz, E.-M., Petrovic, S., Bauer, P., Schaible, W., Muller, T., Schols, L., Klein, C., Berg, D., Meyer, P. T., Schulz, J. B., Wollnik, B., Tong, L., Krüger, R., & Riess, O. (2004). Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7). Human Mutation, 24 (4), 321-9. doi:10.1002/humu.20089 Peer Reviewed verified by ORBi |
Krüger, R. (2004). The role of synphilin-1 in synaptic function and protein degradation. Cell and Tissue Research, 318 (1), 195-9. doi:10.1007/s00441-004-0953-z Peer reviewed |
Muller, T., Przuntek, H., Krüger, R., & Mackowiak, A. (2004). Antiapoptotic effects of budipine. Journal of Neural Transmission, 111 (10-11), 1365-73. doi:10.1007/s00702-004-0157-4 Peer reviewed |
Kobayashi, H., Krüger, R., Markopoulou, K., Wszolek, Z., Chase, B., Taka, H., Mineki, R., Murayama, K., Riess, O., Mizuno, Y., & Hattori, N. (2003). Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease. Brain : a journal of neurology, 126 (Pt 1), 32-42. doi:10.1093/brain/awg010 Peer reviewed |
Marx, F. P., Holzmann, C., Strauss, K. M., Li, L., Eberhardt, O., Gerhardt, E., Cookson, M. R., Hernandez, D., Farrer, M. J., Kachergus, J., Engelender, S., Ross, C. A., Berger, K., Schols, L., Schulz, J. B., Riess, O., & Krüger, R. (2003). Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. Human molecular genetics, 12 (11), 1223-31. doi:10.1093/hmg/ddg134 Peer reviewed |
Thiex, R., Krüger, R., Friese, S., Gronewaller, E., & Kuker, W. (2003). Giant cavernoma of the brain stem: value of delayed MR imaging after contrast injection. European Radiology, 13 Suppl 6, 219-25. doi:10.1007/s00330-002-1772-9 Peer Reviewed verified by ORBi |
Riess, O., Berg, D., Krüger, R., & Schulz, J. B. (2003). Therapeutic strategies for Parkinson's disease based on data derived from genetic research. Journal of Neurology, 250 Suppl 1, 3-10. doi:10.1007/s00415-003-1101-3 Peer Reviewed verified by ORBi |
Schulte, T., Bohringer, S., Schols, L., Muller, T., Fischer, C., Riess, O., Przuntek, H., Berger, K., Epplen, J. T., & Krüger, R. (2003). Modulation of disease risk according to a cathepsin D / apolipoprotein E genotype in Parkinson's disease. Journal of Neural Transmission, 110 (7), 749-55. doi:10.1007/s00702-003-0832-x Peer reviewed |
Holzmann, C., Krüger, R., Saecker, A. M. M. V., Schmitt, I., Schols, L., Berger, K., & Riess, O. (2003). Polymorphisms of the alpha-synuclein promoter: expression analyses and association studies in Parkinson's disease. Journal of Neural Transmission, 110 (1), 67-76. doi:10.1007/s00702-002-0769-5 Peer reviewed |
Krüger, R., Fischer, C., Schulte, T., Strauss, K. M., Muller, T., Woitalla, D., Berg, D., Hungs, M., Gobbele, R., Berger, K., Epplen, J. T., Riess, O., & Schols, L. (2003). Mutation analysis of the neurofilament M gene in Parkinson's disease. Neuroscience Letters, 351 (2), 125-9. doi:10.1016/S0304-3940(03)00903-0 Peer reviewed |
Krüger, R., Eberhardt, O., Riess, O., & Schulz, J. B. (2002). Parkinson's disease: one biochemical pathway to fit all genes? Trends in Molecular Medicine, 8 (5), 236-40. doi:10.1016/S1471-4914(02)02333-X Peer Reviewed verified by ORBi |
Rahner, N., Holzmann, C., Krüger, R., Schols, L., Berger, K., & Riess, O. (2002). Neurofilament L gene is not a genetic factor of sporadic and familial Parkinson's disease. Brain research, 951 (1), 82-6. doi:10.1016/S0006-8993(02)03138-4 Peer reviewed |
Riess, O., Krüger, R., & Schulz, J. B. (2002). Spectrum of phenotypes and genotypes in Parkinson's disease. Journal of Neurology, 249 Suppl 3, 15-20. doi:10.1007/s00415-002-1303-2 Peer Reviewed verified by ORBi |
Ubl, A., Berg, D., Holzmann, C., Krüger, R., Berger, K., Arzberger, T., Bornemann, A., & Riess, O. (2002). 14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta. Molecular Brain Research, 108 (1-2), 33-9. doi:10.1016/S0169-328X(02)00510-7 Peer Reviewed verified by ORBi |
 | Wintermeyer, P., Riess, O., Schols, L., Przuntek, H., Miterski, B., Epplen, J. T., & Krüger, R. (2002). Mutation analysis and association studies of nuclear factor-kappaB1 in sporadic Parkinson's disease patients. Journal of Neural Transmission, 109 (9), 1181-8. doi:10.1007/s00702-001-0688-x Peer reviewed |
Schulte, T., Schols, L., Muller, T., Woitalla, D., Berger, K., & Krüger, R. (2002). Polymorphisms in the interleukin-1 alpha and beta genes and the risk for Parkinson's disease. Neuroscience Letters, 326 (1), 70-2. doi:10.1016/S0304-3940(02)00301-4 Peer reviewed |
Krüger, R., Kuhn, W., Leenders, K. L., Sprengelmeyer, R., Muller, T., Woitalla, D., Portman, A. T., Maguire, R. P., Veenma, L., Schroder, U., Schols, L., Epplen, J. T., Riess, O., & Przuntek, H. (2001). Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers. Neurology, 56 (10), 1355-62. doi:10.1212/WNL.56.10.1355 Peer reviewed |
Krüger, R., Schols, L., Muller, T., Kuhn, W., Woitalla, D., Przuntek, H., Epplen, J. T., & Riess, O. (2001). Evaluation of the gamma-synuclein gene in German Parkinson's disease patients. Neuroscience Letters, 310 (2-3), 191-3. doi:10.1016/S0304-3940(01)02127-9 Peer reviewed |
Schols, L., Peters, S., Szymanski, S., Krüger, R., Lange, S., Hardt, C., Riess, O., & Przuntek, H. (2000). Extrapyramidal motor signs in degenerative ataxias. Archives of neurology, 57 (10), 1495-500. doi:10.1001/archneur.57.10.1495 Peer reviewed |
Miterski, B., Krüger, R., Wintermeyer, P., & Epplen, J. T. (2000). PCR/SSCP detects reliably and efficiently DNA sequence variations in large scale screening projects. Combinatorial chemistry & high throughput screening, 3 (3), 211-8. doi:10.2174/1386207003331607 Peer reviewed |
Krüger, R., Menezes-Saecker, A. M., Schols, L., Kuhn, W., Muller, T., Woitalla, D., Berg, D., Berger, K., Przuntek, H., Epplen, J. T., & Riess, O. (2000). Genetic analysis of the alpha2-macroglobulin gene in early- and late-onset Parkinson's disease. Neuroreport, 11 (11), 2439-42. doi:10.1097/00001756-200008030-00020 Peer reviewed |
Riess, O., Kuhn, W., & Krüger, R. (2000). Genetic influence on the development of Parkinson's disease. Journal of Neurology, 247 Suppl 2, 69-74. Peer Reviewed verified by ORBi |
Wintermeyer, P., Krüger, R., Kuhn, W., Muller, T., Woitalla, D., Berg, D., Leroy, E., Polymeropoulos, M., Berger, K., Przuntek, H., Schols, L., Epplen, J. T., & Riess, O. (2000). Mutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients. Neuroreport, 11 (10), 2079-82. doi:10.1097/00001756-200007140-00004 Peer reviewed |
Krüger, R., Hardt, C., Tschentscher, F., Jackel, S., Kuhn, W., Muller, T., Werner, J., Woitalla, D., Berg, D., Kuhnl, N., Fuchs, G. A., Santos, E. J., Przuntek, H., Epplen, J. T., Schols, L., & Riess, O. (2000). Genetic analysis of immunomodulating factors in sporadic Parkinson's disease. Journal of Neural Transmission, 107 (5), 553-62. doi:10.1007/s007020070078 Peer reviewed |
Krüger, R., Muller, T., & Riess, O. (2000). Involvement of alpha-synuclein in Parkinson's disease and other neurodegenerative disorders. Journal of Neural Transmission, 107 (1), 31-40. doi:10.1007/s007020050002 Peer reviewed |
Krüger, R., Vieira-Saecker, A. M., Kuhn, W., Berg, D., Muller, T., Kuhnl, N., Fuchs, G. A., Storch, A., Hungs, M., Woitalla, D., Przuntek, H., Epplen, J. T., Schols, L., & Riess, O. (1999). Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype. Annals of neurology, 45 (5), 611-7. doi:10.1002/1531-8249(199905)45:5<611::AID-ANA9>3.0.CO;2-X Peer reviewed |
Grasbon-Frodl, E. M., Egensperger, R., Kosel, S., Krüger, R., Riess, O., Mehraein, P., & Graeber, M. B. (1999). The alpha1-antichymotrypsin A-allele in German Parkinson disease patients. Journal of Neural Transmission, 106 (7-8), 729-36. doi:10.1007/s007020050193 Peer reviewed |
Krüger, R., Vieira-Sacker, A. M., Kuhn, W., Muller, T., Woitalla, D., Schols, L., Przuntek, H., Epplen, J. T., & Riess, O. (1999). Analysis of the parkin deletion in sporadic and familial Parkinson's disease. Short communication. Journal of Neural Transmission, 106 (2), 159-63. doi:10.1007/s007020050148 Peer reviewed |
Schols, L., Krüger, R., Amoiridis, G., Przuntek, H., Epplen, J. T., & Riess, O. (1998). Spinocerebellar ataxia type 6: genotype and phenotype in German kindreds. Journal of neurology, neurosurgery, and psychiatry, 64 (1), 67-73. doi:10.1136/jnnp.64.1.67 Peer reviewed |
Muller, T., Kuhn, W., Krüger, R., & Przuntek, H. (1998). Selegiline as immunostimulant--a novel mechanism of action? Journal of Neural Transmission. Supplementum, 52, 321-8. doi:10.1007/978-3-7091-6499-0_33 Peer Reviewed verified by ORBi |
Krüger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L., & Riess, O. (1998). Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nature genetics, 18 (2), 106-8. doi:10.1038/ng0298-106 Peer reviewed |
Riess, O., Jakes, R., & Krüger, R. (1998). Genetic dissection of familial Parkinson's disease. Molecular Medicine Today, 4 (10), 438-44. doi:10.1016/S1357-4310(98)01343-4 Peer Reviewed verified by ORBi |
Wilfried, K., Muller, T., Krüger, R., & Horst, P. (1996). Selegiline stimulates biosynthesis of cytokines interleukin-1 beta and interleukin-6. Neuroreport, 7 (18), 2847-8. doi:10.1097/00001756-199611250-00007 Peer reviewed |