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LANDOULSI Zied

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Bioinformatics Core

Main Referenced Co-authors
MAY, Patrick  (20)
KRÜGER, Rejko  (13)
PAVELKA, Lukas  (11)
PACHCHEK, Sinthuja  (8)
BOBBILI, Dheeraj Reddy  (7)
Main Referenced Keywords
Parkinson's disease (10); Dementia (2); Epilepsy (2); GBA (2); Gut microbiome (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (15)
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (13)
LIH - Luxembourg Institute of Health (6)
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (5)
Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group) (3)
Main Referenced Disciplines
Neurology (15)
Genetics & genetic processes (11)
Microbiology (5)
Human health sciences: Multidisciplinary, general & others (3)
Biochemistry, biophysics & molecular biology (3)

Publications (total 21)

The most downloaded
135 downloads
International League Against Epilepsy Consortium on Complex Epilepsies Krause, R., Landoulsi, Z., May, P., Krause, R., Berkovic, S. F., Cavalleri, G. L., & Koeleman, B. P. (2022). Genome-wide meta-analysis of over 29,000 people with epilepsy reveals 26 loci and subtype-specific genetic architecture. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51794. doi:10.1101/2022.06.08.22276120 https://hdl.handle.net/10993/51794

The most cited

142 citations (WOS)

Smajic, S., Prada-Medina, C. A., Landoulsi, Z., Ghelfi, J., Delcambre, S., Dietrich, C., Jarazo, J., Henck, J., Balachandran, S., Pachchek, S., Morris, C. M., Antony, P., Timmermann, B., Sauer, S., Pereira, S. L., Schwamborn, J. C., May, P., Grünewald, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446 https://hdl.handle.net/10993/49712

AHO, V., KLEE, M., LANDOULSI, Z., Heintz-Buschart, A., PAVELKA, L., LEIST, A., KRÜGER, R., MAY, P., WILMES, P., & NCER-PD Consortium. (06 April 2024). Gut microbiome is not associated with mild cognitive impairment in Parkinson's disease. NPJ Parkinson's Disease, 10 (1), 78. doi:10.1038/s41531-024-00687-1
Peer Reviewed verified by ORBi

KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19
Peer reviewed

LANDOULSI, Z.* , PACHCHEK, S.* , BOBBILI, D. R., PAVELKA, L., MAY, P.* , KRÜGER, R.* , & NCER-PD consortium. (20 December 2023). Genetic landscape of Parkinson’s disease and related diseases in Luxembourg. Frontiers in Aging Neuroscience, 15. doi:10.3389/fnagi.2023.1282174
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

PACHCHEK, S.* , LANDOULSI, Z.* , PAVELKA, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Reddy Bobbili, D., Casadei, N., MAY, P.* , KRÜGER, R.* , & NCER-PD Consortium. (23 November 2023). Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson's study. NPJ Parkinson's Disease, 9 (1), 156. doi:10.1038/s41531-023-00595-w
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Klee, M., Aho, V., May, P., Heintz-Buschart, A., Landoulsi, Z., Jonsdottir, S., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium. (November 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome. Presentation in symposium: Social determinants of brain health: From the search for mechanisms to recommendations to increase equity [Paper presentation]. Annual Meeting of the Gerontological Society of America.

AHO, V., KLEE, M., LANDOULSI, Z., Heintz-Buschart, A., PAVELKA, L., LEIST, A.* , Krüger, R.* , MAY, P.* , & WILMES, P.*. (2023). Mild cognitive impairment is not associated with gut microbiota alterations in Parkinson’s disease. (v1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57437. doi:10.21203/rs.3.rs-3372525/v1
* These authors have contributed equally to this work.

MULICA, P., Venegas, C., LANDOULSI, Z., BADANJAK, K., DELCAMBRE, S., TZIORTZIOU, M., HEZZAZ, S., Ghelfi, J., SMAJIC, S., SCHWAMBORN, J. C., Krüger, R., ANTONY, P., MAY, P., GLAAB, E., GRÜNEWALD, A.* , & Pereira, S. L.*. (20 September 2023). Comparison of two protocols for the generation of iPSC-derived human astrocytes. Biological Procedures Online, 25 (1), 26. doi:10.1186/s12575-023-00218-x
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Stevelink, R., Campbell, C., Chen, S., Abou-Khalil, B., Adesoji, O. M., Afawi, Z., Amadori, E., Anderson, A., Anderson, J., Andrade, D. M., Annesi, G., Auce, P., Avbersek, A., Bahlo, M., Baker, M. D., Balagura, G., Balestrini, S., Barba, C., Barboza, K., ... Epilepsies, I. L. A. E. C. O. C. (2023). GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture. Nature Genetics. doi:10.1038/s41588-023-01485-w
Peer Reviewed verified by ORBi

Klee, M., Aho, V., May, P., Heintz-Buschart, A., Landoulsi, Z., Jonsdottir, S., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium, (Other coll.). (July 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome [Poster presentation]. Alzheimer’s Association (AAIC) Conference.

Arena, G., Landoulsi, Z., Grossmann, D., Vitali, A., Delcambre, S., Baron, A., Antony, P., Boussaad, I., Bobbili, D. R., Sreelatha, A. A. K., Pavelka, L., Klein, C., Seibler, P., Glaab, E., Sharma, M., Krüger, R., May, P., & Grünewald, A. (2023). Polygenic risk scores validated in patient-derived cells stratify for mitochondrial subtypes of Parkinson\textquoterights disease 2023.05.12.23289877. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55367. doi:10.1101/2023.05.12.23289877

Peiris, S., Landoulsi, Z., Pavelka, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Bobbili, D. R., Casadei, N., May, P., Krüger, R., & Consortium, T. N.-P. (2023). Accurate long-read sequencing identified GBA variants as a major genetic risk factor in the Luxembourg Parkinson\textquoterights study 2023.03.29.23287880. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55244. doi:10.1101/2023.03.29.23287880

Sugier, P.-E., Lucotte, E. A., Domenighetti, C., Law, M. H., Iles, M. M., Brown, K., Amos, C., McKay, J. D., Hung, R. J., Karimi, M., Bacq-Daian, D., Boland-Augé, A., Olaso, R., Deleuze, J.-F., Lesueur, F., Ostroumova, E., Kesminiene, A., de Vathaire, F., Guénel, P., ... Elbaz, A. (14 February 2023). Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers. Movement Disorders, n/a (n/a). doi:10.1002/mds.29337
Peer Reviewed verified by ORBi

Rauschenberger, A., Landoulsi, Z., van de Wiel, M. A., & Glaab, E. (2023). Penalised regression with multiple sources of prior effects. Bioinformatics, in press. doi:10.48550/arXiv.2212.08581
Peer Reviewed verified by ORBi

Weiss, D., Landoulsi, Z., May, P., Sharma, M., Schüpbach, M., You, H., Corvol, J. C., Paschen, S., Helmers, A.-K., Barbe, M., Fink, G., Kühn, A. A., Courbon, C. B., Wojtecki, L., Damier, P., Fraix, V., Houeto, J.-L., Regis, J., Sixel-Döring, F., ... Krüger, R. (2022). Genetic stratification of motor and QoL outcomes in Parkinson's disease in the EARLYSTIM study. Parkinsonism and Related Disorders. doi:10.1016/J.PARKRELDIS.2022.08.025
Peer Reviewed verified by ORBi

International League Against Epilepsy Consortium on Complex Epilepsies Krause, R., Landoulsi, Z., May, P., Krause, R., Berkovic, S. F., Cavalleri, G. L., & Koeleman, B. P. (2022). Genome-wide meta-analysis of over 29,000 people with epilepsy reveals 26 loci and subtype-specific genetic architecture. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51794. doi:10.1101/2022.06.08.22276120

Grover, S., Ashwin, A. K. S., Pihlstrom, L., Domenighetti, C., Schulte, C., Sugier, P.-E., Radivojkov-Blagojevic, M., Lichtner, P., Mohamed, O., Portugal, B., Landoulsi, Z., May, P., Bobbili, D. R., Edsall, C., Bartusch, F., Hanussek, M., Krüger, J., Hernandez, D. G., Blauwendraat, C., ... consortium, E. I. P. T. D. C.-P. D. (2022). Genome-wide Association and Meta-analysis of Age-at-Onset in Parkinson Disease: Evidence From COURAGE-PD Consortium 10.1212/WNL.0000000000200699. Neurology. doi:10.1212/WNL.0000000000200699
Peer reviewed

Liu, H., Dehestani, M., Blauwendraat, C., Makarious, M. B., Leonard, H., Kim, J. J., Schulte, C., Noyce, A., Jacobs, B. M., Foote, I., Sharma, M., International Parkinson's Disease Genomics Consortium, Comprehensive Unbiased Risk Factor Assessment For Environment in Parkinson's Disease Consortium, Landoulsi, Z., Krüger, R., May, P., Bobbili, D. R., Pavelka, L., Nalls, M., Singleton, A., ... Bandres-Ciga, S. (2022). Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors. Annals of Neurology. doi:10.1002/ana.26416
Peer Reviewed verified by ORBi

Smajic, S., Prada-Medina, C. A., Landoulsi, Z., Ghelfi, J., Delcambre, S., Dietrich, C., Jarazo, J., Henck, J., Balachandran, S., Pachchek, S., Morris, C. M., Antony, P., Timmermann, B., Sauer, S., Pereira, S. L., Schwamborn, J. C., May, P., Grünewald, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446
Peer Reviewed verified by ORBi

Pavelka, L., Rauschenberger, A., Landoulsi, Z., Pachchek, S., Marques, T., Gomes, C., Glaab, E., May, P., Krüger, R., & NCER-PD, C. (2022). Body-First Subtype of Parkinson's Disease with Probable REM-Sleep Behavior Disorder Is Associated with Non-Motor Dominant Phenotype. Journal of Parkinson's Disease. doi:10.3233/JPD-223511
Peer Reviewed verified by ORBi

Pavelka, L., Rauschenberger, A., Landoulsi, Z., Pachchek, S., May, P., Glaab, E., NCER-PD, C., & Krüger, R. (Other coll.). (2022). Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes. NPJ Parkinson's Disease, 9 (8), 102. doi:10.1038/s41531-022-00342-7
Peer Reviewed verified by ORBi

Smajic, S., Prada-Medina, C. A., Landoulsi, Z., Dietrich, C., Jarazo, J., Henck, J., Balachan, S., Pachchek, S., Morris, C. M., Antony, P., Timmermann, B., Sauer, S., Schwamborn, J. C., May, P., Grünewald, A., & Spielmann, M. (2020). Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson’s disease. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/49376.

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