Profil

PACHCHEK Sinthuja

ORCID
0000-0002-9182-4966
Main Referenced Co-authors
MAY, Patrick  (9)
LANDOULSI, Zied  (8)
KRÜGER, Rejko  (6)
PAVELKA, Lukas  (4)
GLAAB, Enrico  (3)
Main Referenced Keywords
Parkinson's disease (4); Dementia (2); GBA (2); Long-read sequencing (2); Neurology (clinical) (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (8)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (7)
LIH - Luxembourg Institute of Health (4)
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (3)
ULHPC - University of Luxembourg: High Performance Computing (2)
Main Referenced Disciplines
Neurology (7)
Genetics & genetic processes (5)
Human health sciences: Multidisciplinary, general & others (2)
Biochemistry, biophysics & molecular biology (2)
Biotechnology (2)

Publications (total 10)

The most downloaded
90 downloads
SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., GHELFI, J., DELCAMBRE, S., Dietrich, C., JARAZO, J., Henck, J., Balachandran, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., Pereira, S. L., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446 https://hdl.handle.net/10993/49712

The most cited

154 citations (WOS)

SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., GHELFI, J., DELCAMBRE, S., Dietrich, C., JARAZO, J., Henck, J., Balachandran, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., Pereira, S. L., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446 https://hdl.handle.net/10993/49712

KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19
Peer reviewed

LANDOULSI, Z.* , PACHCHEK, S.* , BOBBILI, D. R., PAVELKA, L., MAY, P.* , KRÜGER, R.* , & NCER-PD consortium. (20 December 2023). Genetic landscape of Parkinson’s disease and related diseases in Luxembourg. Frontiers in Aging Neuroscience, 15. doi:10.3389/fnagi.2023.1282174
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

PACHCHEK, S.* , LANDOULSI, Z.* , PAVELKA, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Reddy Bobbili, D., Casadei, N., MAY, P.* , KRÜGER, R.* , & NCER-PD Consortium. (23 November 2023). Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson's study. NPJ Parkinson's Disease, 9 (1), 156. doi:10.1038/s41531-023-00595-w
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

PACHCHEK, S. (2023). DECIPHERING THE GENETIC ARCHITECTURE OF PARKINSON’S DISEASE IN THE LUXEMBOURGISH POPULATION [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58225

PEIRIS, S., LANDOULSI, Z., PAVELKA, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., BOBBILI, D. R., Casadei, N., MAY, P., KRÜGER, R., & Consortium, T. N.-P. (2023). Accurate long-read sequencing identified GBA variants as a major genetic risk factor in the Luxembourg Parkinson\textquoterights study 2023.03.29.23287880. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55244. doi:10.1101/2023.03.29.23287880

Vollstedt, E.-J., Schaake, S., Lohmann, K., Padmanabhan, S., Brice, A., Lesage, S., Tesson, C., Vidailhet, M., Wurster, I., Hentati, F., Mirelman, A., Giladi, N., Karen, M., Waters, C., Fahn, S., Kasten, M., Brüggemann, N., Borsche, M., Foroud, T., ... Zimprich, A. (24 January 2023). Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort. Movement Disorders, 38 (2), 286--303. doi:10.1002/mds.29288
Peer Reviewed verified by ORBi

SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., GHELFI, J., DELCAMBRE, S., Dietrich, C., JARAZO, J., Henck, J., Balachandran, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., Pereira, S. L., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (29 April 2022). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain: a Journal of Neurology, 145 (3), 964-978. doi:10.1093/brain/awab446
Peer Reviewed verified by ORBi

Pavelka, L., RAUSCHENBERGER, A., LANDOULSI, Z., PACHCHEK, S., MARQUES, T., GOMES, C., GLAAB, E., MAY, P., KRÜGER, R., & NCER-PD, C. (2022). Body-First Subtype of Parkinson's Disease with Probable REM-Sleep Behavior Disorder Is Associated with Non-Motor Dominant Phenotype. Journal of Parkinson's Disease. doi:10.3233/JPD-223511
Peer Reviewed verified by ORBi

Pavelka, L., RAUSCHENBERGER, A., LANDOULSI, Z., PACHCHEK, S., MAY, P., GLAAB, E., NCER-PD, C., & KRÜGER, R. (Other coll.). (2022). Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes. NPJ Parkinson's Disease, 9 (8), 102. doi:10.1038/s41531-022-00342-7
Peer Reviewed verified by ORBi

SMAJIC, S., Prada-Medina, C. A., LANDOULSI, Z., Dietrich, C., JARAZO, J., Henck, J., Balachan, S., PACHCHEK, S., Morris, C. M., ANTONY, P., Timmermann, B., Sauer, S., SCHWAMBORN, J. C., MAY, P., GRÜNEWALD, A., & Spielmann, M. (2020). Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson’s disease. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/49376.

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