Profil

PAVELKA Lukas

University of Luxembourg

Main Referenced Co-authors
KRÜGER, Rejko  (18)
MAY, Patrick  (15)
LANDOULSI, Zied  (11)
PAULY, Claire  (8)
LEIST, Anja  (6)
Main Referenced Keywords
Parkinson's disease (9); Neurology (clinical) (3); GBA (2); Gut microbiome (2); Long-read sequencing (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (14)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (12)
LIH - Luxembourg Institute of Health (7)
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (3)
Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group) (3)
Main Referenced Disciplines
Neurology (15)
Genetics & genetic processes (10)
Microbiology (5)
Neurosciences & behavior (3)
Immunology & infectious disease (2)

Publications (total 21)

The most downloaded
422 downloads
Snoeck, C. J., Vaillant, M., Abdelrahman, T., Satagopam, V., Turner, J., Beaumont, K., Gomes, C., Fritz, J., Schröder, V., Kaysen, A., Pavelka, L., Stute, L., Ramos Meyers, G., Pauly, L., Hansen, M., Pauly, C., Aguayo, G. A., Perquin, M., Hanff, A.-M., ... Krüger, R. (2020). Prevalence of SARS-CoV-2 infection in the Luxembourgish population: the CON-VINCE study. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/44961. doi:10.1101/2020.05.11.20092916 https://hdl.handle.net/10993/44961

The most cited

52 citations (WOS)

Hipp Epouse D'amico, G., Vaillant, M., Diederich, N. J., Roomp, K., Satagopam, V., Banda, P., Sandt, E., Mommaerts, K., Schmitz, S., Longhino, L., Schweicher, A., Hanff, A.-M., Nicolai, B., Kolber, P. L., Reiter, D., Pavelka, L., Binck, S., Pauly, C., Geffers, L., ... Krüger, R. (29 October 2018). The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis. Frontiers in Aging Neuroscience, 10, 326. doi:10.3389/fnagi.2018.00326 https://hdl.handle.net/10993/37739

AHO, V., KLEE, M., LANDOULSI, Z., Heintz-Buschart, A., PAVELKA, L., LEIST, A., KRÜGER, R., MAY, P., WILMES, P., & NCER-PD Consortium. (06 April 2024). Gut microbiome is not associated with mild cognitive impairment in Parkinson's disease. NPJ Parkinson's Disease, 10 (1), 78. doi:10.1038/s41531-024-00687-1
Peer Reviewed verified by ORBi

KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19
Peer reviewed

LANDOULSI, Z.* , PACHCHEK, S.* , BOBBILI, D. R., PAVELKA, L., MAY, P.* , KRÜGER, R.* , & NCER-PD consortium. (20 December 2023). Genetic landscape of Parkinson’s disease and related diseases in Luxembourg. Frontiers in Aging Neuroscience, 15. doi:10.3389/fnagi.2023.1282174
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

PAVELKA, L., RAWAL, R., GHOSH, S., PAULY, C., PAULY, L., HANFF, A.-M., KOLBER, P. L., JONSDOTTIR, S., MCINTYRE, D., AZAIZ, K., THIRY, E., Vilasboas, L., SOBOLEVA, E., GIRAITIS, M., TSURKALENKO, O., SAPIENZA, S., DIEDERICH, N., KLUCKEN, J., GLAAB, E., ... NCER-PD Consortium. (19 December 2023). Luxembourg Parkinson’s study -comprehensive baseline analysis of Parkinson’s disease and atypical parkinsonism. Frontiers in Neurology, 14. doi:10.3389/fneur.2023.1330321
Peer Reviewed verified by ORBi

PACHCHEK, S.* , LANDOULSI, Z.* , PAVELKA, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Reddy Bobbili, D., Casadei, N., MAY, P.* , KRÜGER, R.* , & NCER-PD Consortium. (23 November 2023). Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson's study. NPJ Parkinson's Disease, 9 (1), 156. doi:10.1038/s41531-023-00595-w
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Capelle, C. M., Ciré, S., Hedin, F., HANSEN, M., PAVELKA, L., GRZYB, K., KYRIAKIS, D., Hunewald, O., Konstantinou, M., Revets, D., TSLAF, V., Marques, T. M., GOMES, C., BARON, A., Domingues, O., Gomez, M., Zeng, N., BETSOU, F., MAY, P., ... Hefeng, F. Q. (20 November 2023). Early-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females. Nature Communications, 14 (1), 7461. doi:10.1038/s41467-023-43053-0
Peer Reviewed verified by ORBi

Klee, M., Aho, V., May, P., Heintz-Buschart, A., Landoulsi, Z., Jonsdottir, S., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium. (November 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome. Presentation in symposium: Social determinants of brain health: From the search for mechanisms to recommendations to increase equity [Paper presentation]. Annual Meeting of the Gerontological Society of America.

AHO, V., KLEE, M., LANDOULSI, Z., Heintz-Buschart, A., PAVELKA, L., LEIST, A.* , Krüger, R.* , MAY, P.* , & WILMES, P.*. (2023). Mild cognitive impairment is not associated with gut microbiota alterations in Parkinson’s disease. (v1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57437. doi:10.21203/rs.3.rs-3372525/v1
* These authors have contributed equally to this work.

Sosero, Y. L., Bandres-Ciga, S., Ferwerda, B., Tocino, M. T. P., Belloso, D. R., Gómez-Garre, P., Faouzi, J., Taba, P., PAVELKA, L., Marques, T. M., GOMES, C., KOLODKIN, A., MAY, P., Milanowski, L. M., Wszolek, Z. K., Uitti, R. J., Heutink, P., van Hilten, J. J., Simon, D. K., ... Gan-Or, Z. (2023). Dopamine pathway and Parkinson's risk variants are associated with levodopa-induced dyskinesia. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57440. doi:10.1101/2023.08.28.23294610

Klee, M., Aho, V., May, P., Heintz-Buschart, A., Landoulsi, Z., Jonsdottir, S., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A., & NCER-PD Consortium, (Other coll.). (July 2023). Education as risk factor of Mild Cognitive Impairment - the role of the gut microbiome [Poster presentation]. Alzheimer’s Association (AAIC) Conference.

Arena, G., Landoulsi, Z., Grossmann, D., Vitali, A., Delcambre, S., Baron, A., Antony, P., Boussaad, I., Bobbili, D. R., Sreelatha, A. A. K., Pavelka, L., Klein, C., Seibler, P., Glaab, E., Sharma, M., Krüger, R., May, P., & Grünewald, A. (2023). Polygenic risk scores validated in patient-derived cells stratify for mitochondrial subtypes of Parkinson\textquoterights disease 2023.05.12.23289877. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55367. doi:10.1101/2023.05.12.23289877

Peiris, S., Landoulsi, Z., Pavelka, L., Schulte, C., Buena-Atienza, E., Gross, C., Hauser, A.-K., Bobbili, D. R., Casadei, N., May, P., Krüger, R., & Consortium, T. N.-P. (2023). Accurate long-read sequencing identified GBA variants as a major genetic risk factor in the Luxembourg Parkinson\textquoterights study 2023.03.29.23287880. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55244. doi:10.1101/2023.03.29.23287880

Capelle, C., Cire, S., Hansen, M., Pavelka, L., Hedin, F., Konstantinou, M., Revets, D., Tslaf, V., Marques, T., Baron, A., Domingues, O., Zeng, N., May, P., Cosma, A., Balling, R., Krüger, R., Ollert, M., & He, F. (2022). Early-to-mid idiopathic Parkinson’s disease shows a more cytotoxic but declined CD8-regulatory peripheral immune profile. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51989. doi:10.21203/rs.3.rs-1834770/v1

Grover, S., Ashwin, A. K. S., Pihlstrom, L., Domenighetti, C., Schulte, C., Sugier, P.-E., Radivojkov-Blagojevic, M., Lichtner, P., Mohamed, O., Portugal, B., Landoulsi, Z., May, P., Bobbili, D. R., Edsall, C., Bartusch, F., Hanussek, M., Krüger, J., Hernandez, D. G., Blauwendraat, C., ... consortium, E. I. P. T. D. C.-P. D. (2022). Genome-wide Association and Meta-analysis of Age-at-Onset in Parkinson Disease: Evidence From COURAGE-PD Consortium 10.1212/WNL.0000000000200699. Neurology. doi:10.1212/WNL.0000000000200699
Peer reviewed

Liu, H., Dehestani, M., Blauwendraat, C., Makarious, M. B., Leonard, H., Kim, J. J., Schulte, C., Noyce, A., Jacobs, B. M., Foote, I., Sharma, M., International Parkinson's Disease Genomics Consortium, Comprehensive Unbiased Risk Factor Assessment For Environment in Parkinson's Disease Consortium, Landoulsi, Z., Krüger, R., May, P., Bobbili, D. R., Pavelka, L., Nalls, M., Singleton, A., ... Bandres-Ciga, S. (2022). Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors. Annals of Neurology. doi:10.1002/ana.26416
Peer Reviewed verified by ORBi

Barbuti, P. A., Ohnmacht, J., Santos, B. F., Antony, P., Massart, F., Cruciani, G., Dording, C. M., Pavelka, L., Casadei, N., Kwon, Y.-J., & Krüger, R. (09 November 2021). Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports, 11, 21946. doi:10.1038/s41598-021-01505-x
Peer Reviewed verified by ORBi

Pauly, L., Rauschenberger, A., Pauly, C., Hansen, M., Pavelka, L., Hanff, A.-M., Schröder, V., Leist, A., & Krüger, R. (17 September 2021). The retrograde procedural memory in people with Parkinson’s disease with or without freezing of gait – a cross-sectional study [Poster presentation]. Movement Disorders Society Congress 2021.

Krüger, R., Pavelka, L., Mollenhauer, B., Bloem, B., van Rumund, A., Esselink, R. A. J., Geurtz, B. P. M., Wevers, R. A., & Verbeek, M. M. (2021). Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase. NPJ Parkinson's Disease. doi:10.1038/s41531-021-00172-z
Peer Reviewed verified by ORBi

Snoeck, C. J., Vaillant, M., Abdelrahman, T., Satagopam, V., Turner, J., Beaumont, K., Gomes, C., Fritz, J., Schröder, V., Kaysen, A., Pavelka, L., Stute, L., Ramos Meyers, G., Pauly, L., Hansen, M., Pauly, C., Aguayo, G. A., Perquin, M., Hanff, A.-M., ... Krüger, R. (2020). Prevalence of SARS-CoV-2 infection in the Luxembourgish population: the CON-VINCE study. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/44961. doi:10.1101/2020.05.11.20092916

Simons, J., Vaillant, M., Hipp Epouse D'amico, G., Pavelka, L., Stute, L., Pauly, C., & Krüger, R. (2019). Multilingual Validation of the First French Version of Munich Dysphagia Test-Parkinson's Disease (MDT-PD) in the Luxembourg Parkinson's Study. Frontiers in Neurology. doi:10.3389/fneur.2019.01180
Peer Reviewed verified by ORBi

Hipp Epouse D'amico, G., Vaillant, M., Diederich, N. J., Roomp, K., Satagopam, V., Banda, P., Sandt, E., Mommaerts, K., Schmitz, S., Longhino, L., Schweicher, A., Hanff, A.-M., Nicolai, B., Kolber, P. L., Reiter, D., Pavelka, L., Binck, S., Pauly, C., Geffers, L., ... Krüger, R. (29 October 2018). The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis. Frontiers in Aging Neuroscience, 10, 326. doi:10.3389/fnagi.2018.00326
Peer Reviewed verified by ORBi

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