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BUTTINI Manuel

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Neuropathology

Main Referenced Co-authors
GARCIA, Pierre  (12)
GLAAB, Enrico  (12)
BALLING, Rudolf  (7)
HALDER, Rashi  (6)
HEURTAUX, Tony  (6)
Main Referenced Keywords
neurodegeneration (4); Bioinformatics (3); Parkinson's disease (3); Parkinson’s disease (3); transcriptomics (3);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (7)
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) (4)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (3)
Luxembourg Centre for Systems Biomedicine (LCSB) (2)
Luxembourg Centre for Systems Biomedicine (LCSB): Computational Biology (Del Sol Group) (2)
Main Referenced Disciplines
Life sciences: Multidisciplinary, general & others (11)
Neurology (7)
Biochemistry, biophysics & molecular biology (7)
Biotechnology (5)
Human health sciences: Multidisciplinary, general & others (2)

Publications (total 19)

The most downloaded
355 downloads
GARCIA, P., Wemheuer, W., Uriarte, O., MICHELUCCI, A., Masuch, A., Brioschi, S., Weihofen, A., KONCINA, E., COOWAR, D., HEURTAUX, T., GLAAB, E., BALLING, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., ... BUTTINI, M. (2022). Neurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease. Glia. doi:10.1002/glia.24149 https://hdl.handle.net/10993/50437

The most cited

748 citations (Scopus®)

MICHELUCCI, A., CORDES, T., GHELFI, J., PAILOT, A., Reiling, N., Goldmann, O., Binz, T., WEGNER, A., TALLAM, A., Rausell, A., BUTTINI, M., LINSTER, C., Medina, E., BALLING, R., & HILLER, K. (2013). Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1218599110 https://hdl.handle.net/10993/2256

SCHMIT, K.* , GARCIA, P.* , SCIORTINO, A., AHO, V., Pardo Rodriguez, B., THOMAS, M., GERARDY, J.-J., Bastero Acha, I., HALDER, R., CIALINI, C., HEURTAUX, T., Ostahi, I., BUSI, S. B., Grandmougin, L., LOWNDES, T., Singh, Y., Martens, E. C., MITTELBRONN, M., BUTTINI, M.* , & WILMES, P. (26 September 2023). Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease. Cell Reports, 42 (9), 113071. doi:10.1016/j.celrep.2023.113071
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

ALI, M.* , GARCIA, P.* , Laetitia P. Lunkes, SCIORTINO, A., THOMAS, M., HEURTAUX, T., GRZYB, K., HALDER, R., SKUPIN, A., MITTELBRONN, M., BUTTINI, M., & GLAAB, E. (12 May 2023). Gene Regulatory Network Analysis of Single-Cell Transcriptomes from THY-Tau22 Mice Reveals Sex-Dependent Immune Dysregulation associated with Alzheimer-like pathology [Poster presentation]. The 7th Venusberg Meeting on Neuroinflammation, Belval, Luxembourg.
* These authors have contributed equally to this work.

GARCIA, P., Wemheuer, W., Uriarte, O., MICHELUCCI, A., Masuch, A., Brioschi, S., Weihofen, A., KONCINA, E., COOWAR, D., HEURTAUX, T., GLAAB, E., BALLING, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., ... BUTTINI, M. (2022). Neurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease. Glia. doi:10.1002/glia.24149
Peer Reviewed verified by ORBi

ALI, M., Huarte, O., HEURTAUX, T., GARCIA, P., Rodriguez, B. P., GRZYB, K., HALDER, R., SKUPIN, A., BUTTINI, M., & GLAAB, E. (2022). Single-cell transcriptional profiling and gene regulatory network modeling in Tg2576 mice reveal gender-dependent molecular features preceding Alzheimer-like pathologies. Molecular Neurobiology, in press (doi:10.1007/s12035-022-02985-2) (in press). doi:10.1007/s12035-022-02985-2
Peer Reviewed verified by ORBi

Trezzi, J.-P., AHO, V., Jäger, C., Schade, S., Janzen, A., HICKL, O., Kunath, B., THOMAS, M., SCHMIT, K., GARCIA, P., SCIORTINO, A., Martin-Gallausiaux, C., HALDER, R., Huarte, O. U., HEURTAUX, T., Heins-Marroquin, U., Gomez-Giro, G., Weidenbach, K., DELACOUR, L., ... WILMES, P. (2022). An archaeal compound as a driver of Parkinson’s disease pathogenesis. (1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51987. doi:10.21203/rs.3.rs-1827631/v1

Gui, Y., GRZYB, K., THOMAS, M., OHNMACHT, J., GARCIA, P., BUTTINI, M., SKUPIN, A., SAUTER, T., & SINKKONEN, L. (2021). Single‑nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell‑type‑specific gene regulatory variation. Epigenetics and Chromatin. doi:10.1186/s13072-021-00418-3
Peer Reviewed verified by ORBi

THOMAS, M., Gui, Y., GARCIA, P., Karout, M., GOMEZ RAMOS, B., JÄGER, C., Michelucci, A., GAIGNEAUX, A., Kollmus, H., Centeno, A., Schughart, K., Balling, R., Mittelbronn, M., Nadeau, J. H., SAUTER, T., Williams, R. W., SINKKONEN, L., & BUTTINI, M. (2021). Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice. Genes, Brain, and Behavior. doi:10.1111/gbb.12769
Peer Reviewed verified by ORBi

URIARTE HUARTE, O., KYRIAKIS, D., HEURTAUX, T., Pires-Afonso, Y., GRZYB, K., HALDER, R., BUTTINI, M., SKUPIN, A., MITTELBRONN, M., & Michelucci, A. (2021). Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway. Frontiers in Immunology. doi:10.3389/fimmu.2021.639613
Peer Reviewed verified by ORBi

GUI, Y., Thomas, M. H., Garcia, P., Karout, M., HALDER, R., MICHELUCCI, A., Kollmus, H., Zhou, C., Melmed, S., Schughart, K., BALLING, R., MITTELBRONN, M., Nadeau, J. H., Williams, R. W., SAUTER, T., BUTTINI, M., & SINKKONEN, L. (2020). Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging. Frontiers in Genetics. doi:10.3389/fgene.2020.566734
Peer Reviewed verified by ORBi

GLAAB, E., ANTONY, P., Köglsberger, S., Forster, J. I., Cordero-Maldonado, M. L., Crawford, A., GARCIA, P., & BUTTINI, M. (2019). Transcriptome profiling data reveals Ubiquitin-Specific Peptidase 9 knockdown effects. Data in Brief, 25 (1), 104130. doi:10.1016/j.dib.2019.104130
Peer Reviewed verified by ORBi

Köglsberger, S., CORDERO MALDONADO, M. L., ANTONY, P., FORSTER, J., GARCIA, P., BUTTINI, M., CRAWFORD, A. D., & GLAAB, E. (December 2017). Gender-specific expression of ubiquitin-specific peptidase 9 modulates tau expression and phosphorylation: possible implications for tauopathies. Molecular Neurobiology, 54 (10), 7979–7993. doi:10.1007/s12035-016-0299-z
Peer Reviewed verified by ORBi

ASHRAFI, A., GARCIA, P., Kollmus, H., Schughart, K., DEL SOL MESA, A., BUTTINI, M., & GLAAB, E. (October 2017). Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease. Neurobiology of Aging, 58, 30-33. doi:10.1016/j.neurobiolaging.2017.06.008
Peer Reviewed verified by ORBi

Jäger, C., HILLER, K., & BUTTINI, M. (2016). Metabolic Profiling and Quantification of Neurotransmitters in Mouse Brain by Gas Chromatography-Mass Spectrometry: Metabolic Profiling of Neurotransmitters by GC-MS. In J. Auwerx, S. L. Ackerman, S. D. Brown, M. J. Justice, ... J. Nadeau (Eds.), Current Protocols in Mouse Biology (pp. 333--342). Hoboken, NJ, USA, Unknown/unspecified: John Wiley Sons, Inc. doi:10.1002/cpmo.15
Peer reviewed

Ashrafi, A., BUTTINI, M., GARCIA, P., DEL SOL MESA, A., & GLAAB, E. (2016). Exploring therapeutic viability of a non-dopaminergic target for Parkinson’s disease. Movement Disorders, 31 (2), 630.
Peer Reviewed verified by ORBi

Jäger, C.* , GLAAB, E.* , MICHELUCCI, A.* , Binz, T., Köglsberger, S., GARCIA, P., TREZZI, J.-P., GHELFI, J., BALLING, R., & BUTTINI, M. (2015). The Mouse Brain Metabolome: Region-Specific Signatures and Response to Excitotoxic Neuronal Injury. American Journal of Pathology, 185 (6), 1699-1712. doi:10.1016/j.ajpath.2015.02.016
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Fujita, K. A., OSTASZEWSKI, M., Matsuoka, Y., Ghosh, S., GLAAB, E., TREFOIS, C., CRESPO, I., PERUMAL, T. M., JURKOWSKI, W., ANTONY, P., DIEDERICH, N., BUTTINI, M., Kodama, A., SATAGOPAM, V., EIFES, S., DEL SOL MESA, A., SCHNEIDER, R., Kitano, H., & BALLING, R. (2014). Integrating Pathways of Parkinson's Disease in a Molecular Interaction Map. Molecular Neurobiology. doi:10.1007/s12035-013-8489-4
Peer Reviewed verified by ORBi

MICHELUCCI, A., CORDES, T., GHELFI, J., PAILOT, A., Reiling, N., Goldmann, O., Binz, T., WEGNER, A., TALLAM, A., Rausell, A., BUTTINI, M., LINSTER, C., Medina, E., BALLING, R., & HILLER, K. (2013). Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1218599110
Peer Reviewed verified by ORBi

OSTASZEWSKI, M., Fujita, K., Matsuoka, Y., Ghosh, S., GLAAB, E., TREFOIS, C., CRESPO, I., PERUMAL, T. M., JURKOWSKI, W., ANTONY, P., DIEDERICH, N., BUTTINI, M., KOLODKIN, A., Kodama, A., SATAGOPAM, V., BIRYUKOV, M., EIFES, S., DEL SOL MESA, A., SCHNEIDER, R., ... BALLING, R. (09 March 2013). The Parkinson's Disease Map: A Framework for Integration, Curation and Exploration of Disease-related Pathways [Poster presentation]. The 11th International Conference on Alzheimer's & Parkinson's Diseases, Florence, Italy.

TREFOIS, C., Fujita, A. K., OSTASZEWSKI, M., Matsuoka, Y., Ghosh, S., GLAAB, E., Crespo, I., Perumal, T. M., Jurkowski, W., ANTONY, P., DIEDERICH, N., BUTTINI, M., Kodama, A., SATAGOPAM, V., EIFES, S., DEL SOL MESA, A., SCHNEIDER, R., Kitano, H., & BALLING, R. (August 2012). Constructing a comprehensive map of Parkinson’s disease to elucidate underlying mechanisms of its multifaceted molecular pathology [Poster presentation]. The 13th International Conference on Systems Biology.

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