Profil

GARCIA Pierre

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Neuropathology

ORCID
0000-0002-6681-9671
Main Referenced Co-authors
BUTTINI, Manuel  (12)
GLAAB, Enrico  (9)
HEURTAUX, Tony  (5)
THOMAS, Melanie  (5)
HALDER, Rashi  (4)
Main Referenced Keywords
neurodegeneration (4); Alzheimer's disease (3); Parkinson's disease (3); transcriptomics (3); alpha-synuclein (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (6)
Luxembourg Centre for Systems Biomedicine (LCSB) (2)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (2)
Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group) (2)
Institut National Polytechnique de Lorraine / INSERM (1)
Main Referenced Disciplines
Neurology (8)
Life sciences: Multidisciplinary, general & others (7)
Biochemistry, biophysics & molecular biology (5)
Biotechnology (5)
Neurosciences & behavior (3)

Publications (total 15)

The most downloaded
397 downloads
GARCIA, P. (June 2009). The essential role of lipids in Alzheimer’s disease. Biochimie, 6, 804-809. doi:10.1016/j.biochi.2009.03.004 https://hdl.handle.net/10993/17248

The most cited

109 citations (Scopus®)

GARCIA, P. (02 June 2010). Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease. Journal of Neuroscience, 30 (22), 7516-7527. doi:10.1523/JNEUROSCI.4182-09.2010 https://hdl.handle.net/10993/15998

SCHMIT, K.* , GARCIA, P.* , SCIORTINO, A., AHO, V., Pardo Rodriguez, B., THOMAS, M., GERARDY, J.-J., Bastero Acha, I., HALDER, R., CIALINI, C., HEURTAUX, T., Ostahi, I., BUSI, S. B., Grandmougin, L., LOWNDES, T., Singh, Y., Martens, E. C., MITTELBRONN, M., BUTTINI, M.* , & WILMES, P. (26 September 2023). Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease. Cell Reports, 42 (9), 113071. doi:10.1016/j.celrep.2023.113071
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

ALI, M.* , GARCIA, P.* , Laetitia P. Lunkes, SCIORTINO, A., THOMAS, M., HEURTAUX, T., GRZYB, K., HALDER, R., SKUPIN, A., MITTELBRONN, M., BUTTINI, M., & GLAAB, E. (12 May 2023). Gene Regulatory Network Analysis of Single-Cell Transcriptomes from THY-Tau22 Mice Reveals Sex-Dependent Immune Dysregulation associated with Alzheimer-like pathology [Poster presentation]. The 7th Venusberg Meeting on Neuroinflammation, Belval, Luxembourg.
* These authors have contributed equally to this work.

GARCIA, P., Wemheuer, W., Uriarte, O., MICHELUCCI, A., Masuch, A., Brioschi, S., Weihofen, A., KONCINA, E., COOWAR, D., HEURTAUX, T., GLAAB, E., BALLING, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., ... BUTTINI, M. (2022). Neurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease. Glia. doi:10.1002/glia.24149
Peer Reviewed verified by ORBi

ALI, M., Huarte, O., HEURTAUX, T., GARCIA, P., Rodriguez, B. P., GRZYB, K., HALDER, R., SKUPIN, A., BUTTINI, M., & GLAAB, E. (2022). Single-cell transcriptional profiling and gene regulatory network modeling in Tg2576 mice reveal gender-dependent molecular features preceding Alzheimer-like pathologies. Molecular Neurobiology, in press (doi:10.1007/s12035-022-02985-2) (in press). doi:10.1007/s12035-022-02985-2
Peer Reviewed verified by ORBi

Trezzi, J.-P., AHO, V., Jäger, C., Schade, S., Janzen, A., HICKL, O., Kunath, B., THOMAS, M., SCHMIT, K., GARCIA, P., SCIORTINO, A., Martin-Gallausiaux, C., HALDER, R., Huarte, O. U., HEURTAUX, T., Heins-Marroquin, U., Gomez-Giro, G., Weidenbach, K., DELACOUR, L., ... WILMES, P. (2022). An archaeal compound as a driver of Parkinson’s disease pathogenesis. (1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51987. doi:10.21203/rs.3.rs-1827631/v1

Gui, Y., GRZYB, K., THOMAS, M., OHNMACHT, J., GARCIA, P., BUTTINI, M., SKUPIN, A., SAUTER, T., & SINKKONEN, L. (2021). Single‑nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell‑type‑specific gene regulatory variation. Epigenetics and Chromatin. doi:10.1186/s13072-021-00418-3
Peer Reviewed verified by ORBi

THOMAS, M., Gui, Y., GARCIA, P., Karout, M., GOMEZ RAMOS, B., JÄGER, C., Michelucci, A., GAIGNEAUX, A., Kollmus, H., Centeno, A., Schughart, K., Balling, R., Mittelbronn, M., Nadeau, J. H., SAUTER, T., Williams, R. W., SINKKONEN, L., & BUTTINI, M. (2021). Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice. Genes, Brain, and Behavior. doi:10.1111/gbb.12769
Peer Reviewed verified by ORBi

GLAAB, E., ANTONY, P., Köglsberger, S., Forster, J. I., Cordero-Maldonado, M. L., Crawford, A., GARCIA, P., & BUTTINI, M. (2019). Transcriptome profiling data reveals Ubiquitin-Specific Peptidase 9 knockdown effects. Data in Brief, 25 (1), 104130. doi:10.1016/j.dib.2019.104130
Peer Reviewed verified by ORBi

Köglsberger, S., CORDERO MALDONADO, M. L., ANTONY, P., FORSTER, J., GARCIA, P., BUTTINI, M., CRAWFORD, A. D., & GLAAB, E. (December 2017). Gender-specific expression of ubiquitin-specific peptidase 9 modulates tau expression and phosphorylation: possible implications for tauopathies. Molecular Neurobiology, 54 (10), 7979–7993. doi:10.1007/s12035-016-0299-z
Peer Reviewed verified by ORBi

ASHRAFI, A., GARCIA, P., Kollmus, H., Schughart, K., DEL SOL MESA, A., BUTTINI, M., & GLAAB, E. (October 2017). Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease. Neurobiology of Aging, 58, 30-33. doi:10.1016/j.neurobiolaging.2017.06.008
Peer Reviewed verified by ORBi

Ashrafi, A., BUTTINI, M., GARCIA, P., DEL SOL MESA, A., & GLAAB, E. (2016). Exploring therapeutic viability of a non-dopaminergic target for Parkinson’s disease. Movement Disorders, 31 (2), 630.
Peer Reviewed verified by ORBi

Jäger, C.* , GLAAB, E.* , MICHELUCCI, A.* , Binz, T., Köglsberger, S., GARCIA, P., TREZZI, J.-P., GHELFI, J., BALLING, R., & BUTTINI, M. (2015). The Mouse Brain Metabolome: Region-Specific Signatures and Response to Excitotoxic Neuronal Injury. American Journal of Pathology, 185 (6), 1699-1712. doi:10.1016/j.ajpath.2015.02.016
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Desbène, C., Malaplate-Armand, C., Youssef, I., GARCIA, P., Stenger, C., Sauvée, M., Fischer, N., Rimet, D., Koziel, V., Escanyé, M.-C., Oster, T., Kriem, B., Yen, F. T., Pillot, T., & Olivier, J.-L. (June 2012). Critical role of cPLA2 in Aβ oligomer-induced neurodegeneration and memory deficit. Neurobiology of Aging, 33 (6), 1123-e17-1123-e29. doi:10.1016/j.neurobiolaging.2011.11.008
Peer Reviewed verified by ORBi

GARCIA, P. (02 June 2010). Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease. Journal of Neuroscience, 30 (22), 7516-7527. doi:10.1523/JNEUROSCI.4182-09.2010
Peer Reviewed verified by ORBi

GARCIA, P. (June 2009). The essential role of lipids in Alzheimer’s disease. Biochimie, 6, 804-809. doi:10.1016/j.biochi.2009.03.004
Peer Reviewed verified by ORBi

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