Humans; Female; Male; Middle Aged; Aged; Risk Factors; Mendelian Randomization Analysis; Parkinson Disease/genetics; Parkinson Disease/epidemiology; Body Mass Index; Polymorphism, Single Nucleotide/genetics; Genome-Wide Association Study; Parkinson Disease; Polymorphism, Single Nucleotide; Neurology (clinical)
Abstract :
[en] BACKGROUND AND OBJECTIVES: The role of body mass index (BMI) in Parkinson disease (PD) is unclear. Based on the Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in PD (Courage-PD) consortium, we used 2-sample Mendelian randomization (MR) to replicate a previously reported inverse association of genetically predicted BMI with PD and investigated whether findings were robust in analyses addressing the potential for survival and incidence-prevalence biases. We also examined whether the BMI-PD relation is bidirectional by performing a reverse MR.
METHODS: We used summary statistics from a genome-wide association study (GWAS) to extract the association of 501 single-nucleotide polymorphisms (SNPs) with BMI and from the Courage-PD and international Parkinson Disease Genomics Consortium (iPDGC) to estimate their association with PD. Analyses are based on participants of European ancestry. We used the inverse-weighted method to compute odds ratios (ORIVW per 4.8 kg/m2 [95% CI]) of PD and additional pleiotropy robust methods. We performed analyses stratified by age, disease duration, and sex. For reverse MR, we used SNPs associated with PD from 2 iPDGC GWAS to assess the effect of genetic liability toward PD on BMI.
RESULTS: Summary statistics for BMI are based on 806,834 participants (54% women). Summary statistics for PD are based on 8,919 (40% women) cases and 7,600 (55% women) controls from Courage-PD, and 19,438 (38% women) cases and 24,388 (51% women) controls from iPDGC. In Courage-PD, we found an inverse association between genetically predicted BMI and PD (ORIVW 0.82 [0.70-0.97], p = 0.012) without evidence for pleiotropy. This association tended to be stronger in younger participants (≤67 years, ORIVW 0.71 [0.55-0.92]) and cases with shorter disease duration (≤7 years, ORIVW 0.75 [0.62-0.91]). In pooled Courage-PD + iPDGC analyses, the association was stronger in women (ORIVW 0.85 [0.74-0.99], p = 0.032) than men (ORIVW 0.92 [0.80-1.04], p = 0.18), but the interaction was not statistically significant (p-interaction = 0.48). In reverse MR, there was evidence for pleiotropy, but pleiotropy robust methods showed a significant inverse association.
DISCUSSION: Using an independent data set (Courage-PD), we replicate an inverse association of genetically predicted BMI with PD, not explained by survival or incidence-prevalence biases. Moreover, reverse MR analyses support an inverse association between genetic liability toward PD and BMI, in favor of a bidirectional relation.
Research center :
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group)
Disciplines :
Genetics & genetic processes Neurology
Author, co-author :
Domenighetti, Cloé ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Sugier, Pierre-Emmanuel; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Ashok Kumar Sreelatha, Ashwin; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Schulte, Claudia ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Grover, Sandeep ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Portugal, Berta ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Lee, Pei-Chen ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
BOBBILI, Dheeraj Reddy ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Bioinformatics Core
Radivojkov Blagojevic, Milena; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Lichtner, Peter; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Singleton, Andrew B ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Hernandez, Dena; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Edsall, Connor ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Mellick, George D ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Zimprich, Alexander A; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Pirker, Walter ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Rogaeva, Ekaterina A ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Lang, Anthony E ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Koks, Sulev ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Taba, Pille; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Lesage, Suzanne ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Brice, Alexis ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Corvol, Jean-Christophe ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Chartier-Harlin, Marie-Christine; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Mutez, Eugenie; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Brockmann, Kathrin ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Deutschlander, Angela B ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Hadjigeorgiou, Georgios M ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Dardiotis, Efthimios ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Stefanis, Leonidas; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Simitsi, Athina Maria; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Valente, Enza Maria ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Petrucci, Simona; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Straniero, Letizia ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Zecchinelli, Anna L; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Pezzoli, Gianni ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Brighina, Laura ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Ferrarese, Carlo; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Annesi, Grazia ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Quattrone, Andrea ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Gagliardi, Monica ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Matsuo, Hirotaka; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Nakayama, Akiyoshi ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Hattori, Nobutaka ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Nishioka, Kenya ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Chung, Sun Ju ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Kim, Yun Joong ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Kolber, Pierre; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Van De Warrenburg, Bart P C ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Bloem, Bastiaan R ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Toft, Mathias ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Pihlstrøm, Lasse ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Correia Guedes, Leonor; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Ferreira, Joaquim J ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Bardien, Soraya ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Carr, Jonathan ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Tolosa, Eduardo ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Ezquerra, Mario ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Pastor, Pau ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Diez-Fairen, Monica ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Wirdefeldt, Karin; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Pedersen, Nancy L ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Ran, Caroline ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Belin, Andrea C ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Puschmann, Andreas ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Hellberg, Clara; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Clarke, Carl E ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Morrison, Karen E ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Tan, Manuela M ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Krainc, Dimitri ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Burbulla, Lena F ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Farrer, Matthew ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
KRÜGER, Rejko ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Translational Neuroscience
Gasser, Thomas; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Sharma, Manu; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Elbaz, Alexis ; From the Université Paris-Saclay (C.D., P.-E.S., B.P., A.E.), UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France, Centre for Genetic Epidemiology (A.A.K.S., M.S.), Institute for Clinical Epidemiology and Applied Biometry, and Department for Neurodegenerative Diseases (C.S., K.B., T.G.), Hertie Institute for Clinical Brain Research, University of Tubingen, German Center for Neurodegenerative Diseases (DZNE) (C.S., K.B., T.G.), Tubingen, Center for Human Genetics (S.G.), Universitatsklinikum Giessen und Marburg, Germany, Department of Public Health (P.-C.L.), National Cheng Kung University, Tainan, Taiwan, Translational Neuroscience (P.M., D.B., R.K.), Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Institute of Human Genetics (M.R.B., P.L.), Helmholtz Zentrum München, Neuherberg, Germany, Molecular Genetics Section (A.B.S., D.H., C.E.), Laboratory of Neurogenetics, and Center for Alzheimer's and Related Dementias (A.B.S.), NIA, NIH, Bethesda, MD, Griffith Institute for Drug Discovery (G.D.M.), Griffith University, Nathan, Australia, Department of Neurology (A.A.Z.), Medical University of Vienna, Department of Neurology (W.P.), Wilhelminenspital, Austria, Tanz Centre for Research in Neurodegenerative Diseases (E.A.R., A.E.L.), University of Toronto, Edmond J. Safra Program in Parkinson's Disease (A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology (A.E.L.), University of Toronto, Krembil Brain Institute (A.E.L.), Toronto, Ontario, Canada, Centre for Molecular Medicine and Innovative Therapeutics (S.K.), Murdoch University, Perron Institute for Neurological and Translational Science (S.K.), Nedlands, Australia, Department of Neurology and Neurosurgery (P.T.), University of Tartu, Neurology Clinic (P.T.), Tartu University Hospital, Estonia, Department of Neurologie (S.L., A.B., J.-C.C.), Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Sorbonne Université, Assistance Publique Hôpitaux de Paris (J.-C.C.), Department of Neurology, CIC Neurosciences, Univ. Lille (M.-C.C.-H., E.M.), Inserm, CHU Lille, UMR-S 1172-LilNCog-Centre de Recherche Lille Neurosciences & Cognition, France, Department of Neurology (A.B.D.), Ludwig Maximilians University of Munich, Department of Neurology (A.B.D.), Max Planck Institute of Psychiatry, Munich, Germany, Department of Neurology and Department of Clinical Genomics (A.B.D.), Mayo Clinic Florida, Jacksonville, Department of Neurology (G.M.H., E.D.), Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa, Greece, Department of Neurology (G.M.H.), Medical School, University of Cyprus, Nicosia, 1st Department of Neurology (L. Stefanis, A.M.S.), Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Center of Clinical Research, Experimental Surgery and Translational Research (L. Stefanis), Biomedical Research Foundation of the Academy of Athens, Greece, Department of Molecular Medicine (E.M.V.), University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation (E.M.V.), Pavia, UOC Medical Genetics and Advanced Cell Diagnostics (S.P.), S. Andrea University Hospital, Rome, Department of Clinical and Molecular Medicine (S.P.), University of Rome, Department of Biomedical Sciences (L. Straniero), Humanitas University, Milan, Parkinson Institute (A.L.Z.), Azienda Socio Sanitaria Territoriale (ASST) Gaetano Pini/CTO, Milano, Parkinson Institute (G.P.), Fontazione Grigioni-Via Zuretti, Milan, Department of Neurology (L.B., C.F.), San Gerardo Hospital, Monza, Department of Medicine and Surgery and Milan Center for Neuroscience (L.B., C.F.), University of Milano Bicocca, Milano, Institute for Biomedical Research and Innovation (G.A.), National Research Council, Cosenza, Institute of Neurology (A.Q.), Magna Graecia University, Institute of Molecular Bioimaging and Physiology National Research Council (M.G.), Catanzaro, Italy, Department of Integrative Physiology and Bio-Nano Medicine (H.M., A.N.), National Defense Medical College, Saitama, Department of Neurology (N.H., K.N.), Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan, Department of Neurology (S.J.C.), Asan Medical Center, University of Ulsan College of Medicine, Department of Neurology (Y.J.K.), Yonsei University College of Medicine, Seoul, South Korea, Neurology (P.K., R.K.), Centre Hospitalier de Luxembourg, Department of Neurology (B.P.C.V.D.W., B.R.B.), Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Radboud University Medical Centre, the Netherlands, Department of Neurology (M.T., L.P.), Oslo University Hospital, Norway, Instituto de Medicina Molecular João Lobo Antunes (L.C.G., J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Department of Neurosciences and Mental Health (L.C.G.), Neurology, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN), Laboratory of Clinical Pharmacology and Therapeutics (J.J.F.), Faculdade de Medicina, Universidade de Lisboa, Portugal, Division of Molecular Biology and Human Genetics (S.B.), Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Division of Neurology (J.C.), Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, Parkinson's disease & Movement Disorders Unit (E.T.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) (E.T.), Lab of Parkinson Disease and Other Neurodegenerative Movement Disorders (M.E.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institut de Neurociències, Universitat de Barcelona, Fundació per la Recerca Biomèdica i Social Mútua Terrassa (P.P., M.D.-F.), Terrassa, Movement Disorders Unit (P.P., M.D.-F.), Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain, Department of Clinical Neuroscience (K.W.), Department of Medical Epidemiology and Biostatistics (K.W., N.L.P.), and Department of Neuroscience (C.R., A.C.B.), Karolinska Institutet, Stockholm, Department of Clinical Sciences Lund (A.P., C.H.), Neurology, Skåne University Hospital, Lund University, Sweden, University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust (C.E.C.), Faculty of Medicine (K.E.M.), Health and Life Sciences, Queens University, Belfast, Department of Clinical and Movement Neurosciences (M.M.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom, Department of Neurology (D.K., L.F.B.), Northwestern University Feinberg School of Medicine, Chicago, IL, Metabolic Biochemistry (L.F.B.), Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology (SyNergy) (L.F.B.), German Center for Neurodegenerative Diseases (DZNE) (L.F.B.), Munich, Germany, Department of Neurology (M.F.), McKnight Brain Institute, University of Florida, Gainesville, Parkinson's Research Clinic (R.K.), Centre Hospitalier de Luxembourg, and Transversal Translational Medicine (R.K.), Luxembourg Institute of Health (LIH), Strassen
Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease (COURAGE-PD) Consortium
H2020 - 825664 - JPCOFUND2 - ERA-NET to support the Joint Programming in Neurodegenerative Diseases strategic plan (JPND)
FnR Project :
FNR11264123 - NCER-PD - Ncer-pd, 2015 (01/06/2015-31/05/2023) - Rejko Krüger FNR11583046 - MechEPI - Epileptogenesis Of Genetic Epilepsies, 2017 (01/04/2018-30/06/2021) - Roland Krause FNR14429377 - ProtectMove II - Reduced Penetrance In Hereditary Movement Disorders: Elucidating Mechanisms Of Endogenous Disease Protection, 2020 (01/07/2020-30/06/2023) - Anne Grünewald
Funders :
FNR - Fonds National de la Recherche European Union
Funding text :
This study used data from the Courage-PD (Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson\u2018s Disease) consortium, conducted under a partnership agreement between 35 studies. PG GEN sample collection was funded by the MRC and UK Medical Research Council (through grants received by C.E. Clarke and K.E. Morrison). The sponsors had no role in the study design, data collection, data analysis, data interpretation, the writing of the report, or the decision to submit the paper for publication.The authors thank iPDGC, the GIANT Consortium, and the UK Biobank study for providing summary statistics for these analyses. Additional Courage-PD contributors: Sophia N. Pchelina (Saint Petersburg, Russia; collection of data), Thomas Br\u00A8 ucke (Wien, Austria; collection of data), MarieAnne Loriot (Paris, France; DNA banking), Claire Mulot (Paris, France; DNA banking), Georgia Xiromerisiou (Larissa, Greece; collection of data), Christos Koros (Athens, Greece; collection of data), Matina Maniati (Athens, Greece; collection of data), Maria Bozi (Athens, Greece; collection of data), Micol Avenali (Pavia, Italy; collection of data), Margherita Canesi (Milan, Italy; collection of data), Giorgio Sacilotto (Milan, Italy; collection of data), Michela Zini (Milan, Italy; collection of data), Roberto Cilia (Milan, Italy; collection of data), Francesca Del Sorbo (Milan, Italy; collection of data), Nicoletta Meucci (Milan, Italy; collection of data), Letizia Straniero (Milan, Italy; collection of data), Rosanna Asselta (Milan, Italy; collection of data), Radha Procopio (Catanzaro, Italy; collection of data), Aldo Quattrone (Catanzaro, Italy; collection of data), Manabu Funayama (Tokyo, Japan; collection of data), Aya Ikeda (Tokyo, Japan; collection of data), Takashi Matsushima (Tokyo, Japan; collection of data), Yuanzhe Li (Tokyo, Japan; collection of data), Hiroyo Yoshino (Tokyo, Japan; collection of data), Zied Landoulsi (Luxembourg, Luxembourg; collection of data), Ruben Fer\u0144 andez-Santiago (Barcelona, Spain; collection of data), Nicholas Wood (London, United Kingdom; site supervision), Huw R. Morris (London, United Kingdom; site supervision). This study used data from the Courage-PD (Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson s Disease) consortium, conducted under a partnership agreement between 35 studies. PG GEN sample collection was funded by the MRC and UK Medical Research Council (through grants received by C.E. Clarke and K.E. Morrison). The sponsors had no role in the study design, data collection, data analysis, data interpretation, the writing of the report, or the decision to submit the paper for publication.
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