Profil

PHILIPPIDOU Demetra

University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)

Main Referenced Co-authors
KREIS, Stephanie  (17)
WURTH - MARGUE, Christiane  (13)
BEHRMANN, Iris  (9)
KOZAR, Ines  (5)
REINSBACH, Susanne  (5)
Main Referenced Keywords
Melanoma (5); melanoma (4); cancer (2); Cell Line, Tumor (2); GTP Phosphohydrolases (2);
Main Referenced Unit & Research Centers
ULHPC - University of Luxembourg: High Performance Computing (2)
Department of Life Sciences and Medicine (1)
Life Science Research Unit-University of Luxembourg (1)
University of Luxembourg (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (16)
Life sciences: Multidisciplinary, general & others (1)

Publications (total 17)

The most downloaded
305 downloads
Margue, C., Reinsbach, S., Philippidou, D., Beaume, N., Walters, C., Schneider, J., Nashan, D., Behrmann, I., & Kreis, S. (2015). Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Oncotarget, 6 (14), 12110-27. doi:10.18632/oncotarget.3661 https://hdl.handle.net/10993/24991

The most cited

191 citations (Scopus®)

Philippidou, D., Schmitt, M., Moser, D., Margue, C., Nazarov, P. V., Muller, A., Vallar, L., Nashan, D., Behrmann, I., & Kreis, S. (2010). Signatures of MicroRNAs and selected MicroRNA target genes in human melanoma. Cancer Research, 70 (10), 4163-4173. doi:10.1158/0008-5472.CAN-09-4512 https://hdl.handle.net/10993/4989

GUREGHIAN, V., HERBST, H., KOZAR, I., MIHAJLOVIC, K., Malod-Dognin, N., Ceddia, G., ANGELI, C., WURTH-MARGUE, C., RANDIC, T., PHILIPPIDOU, D., TETSI NOMIGNI, M., HEMEDAN, A., TRANCHEVENT, L.-C., LONGWORTH, J., Bauer, M., BADKAS, A., GAIGNEAUX, A., Muller, A., OSTASZEWSKI, M., ... KREIS, S. (October 2023). A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma. Cancer Gene Therapy, 30 (10), 1330 - 1345. doi:10.1038/s41417-023-00640-z
Peer Reviewed verified by ORBi

Bintener, T., Pires Pacheco, M. I., Philippidou, D., Margue, C., Kishk, A., Del Mistro, G., Di Leo, L., Moscardo Garcia, M., Halder, R., Sinkkonen, L., De Zio, D., Kreis, S., Kulms, D., & Sauter, T. (26 July 2023). Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma. Cell Death and Disease, 14 (468). doi:10.1038/s41419-023-05955-1
Peer reviewed

RANDIC, T., MAGNI, S., PHILIPPIDOU, D., Margue, C., GRZYB, K., PREIS, J. R., WROBLEWSKA, J. P., NAZAROV, P., MITTELBRONN, M., FRAUENKNECHT, K., SKUPIN, A., & KREIS, S. (25 July 2023). Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response. Cell Reports, 42 (7), 112696. doi:10.1016/j.celrep.2023.112696
Peer Reviewed verified by ORBi

Kozar, I., Philippidou, D., Margue, C., Gay, L., Renne, R., & Kreis, S. (2021). Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells. Cancers. doi:10.3390/cancers13051096
Peer Reviewed verified by ORBi

Kirchmeyer, M., Servais, F., Ginolhac, A., Nazarov, P. V., Margue, C., Philippidou, D., Nicot, N., Behrmann, I., Haan, C., & Kreis, S. (2020). Systematic transcriptional profiling of responses to STAT1- and STAT3- activating cytokines in different cancer types. Journal of Molecular Biology. doi:10.1016/j.jmb.2020.09.011
Peer Reviewed verified by ORBi

Walbrecq, G., Lecha, O., Gaigneaux, A., Fougeras, M. R., Philippidou, D., Margue, C., Tetsi Nomigni, M., Bernardin, F., Dittmar, G., Behrmann, I., & Kreis, S. (2020). Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles. Cancers. doi:10.3390/cancers12030692
Peer Reviewed verified by ORBi

Margue, C., Philippidou, D., Kozar, I., Cesi, G., Felten, P., Kulms, D., Letellier, E., Haan, C., & Kreis, S. (February 2019). Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells. Journal of Experimental and Clinical Cancer Research, 38 (1). doi:10.1186/s13046-019-1038-x
Peer Reviewed verified by ORBi

Cesi, G., Philippidou, D., Kozar, I., Kim, Y. J., Bernardin, F., Van Niel, G., Wienecke-Baldacchino, A., Felten, P., Letellier, E., Dengler, S., Nashan, D., Haan, C., & Kreis, S. (2018). A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells. Molecular Cancer, (17:145). doi:10.1186/s12943-018-0886-x
Peer Reviewed verified by ORBi

Kreis, S., Kozar, I., Cesi, G., Margue, C., & Philippidou, D. (2017). Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells. Biochimica et Biophysica Acta. doi:10.1016/j.bbagen.2017.04.005
Peer reviewed

Margue, C., Reinsbach, S., Philippidou, D., Beaume, N., Walters, C., Schneider, J., Nashan, D., Behrmann, I., & Kreis, S. (2015). Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Oncotarget, 6 (14), 12110-27. doi:10.18632/oncotarget.3661
Peer Reviewed verified by ORBi

Margue, C., Philippidou, D., Reinsbach, S., Schmitt, M., Behrmann, I., & Kreis, S. (05 September 2013). New Target Genes of MITF-Induced microRNA-211 Contribute to Melanoma Cell Invasion. PLoS ONE, 8 (9). doi:10.1371/journal.pone.0073473
Peer Reviewed verified by ORBi

Nazarov, P. V. A., Reinsbach, S., Muller, A. A., Nicot, N. A., Philippidou, D., Vallar, L. A., & Kreis, S. (2013). Interplay of microRNAs, transcription factors and target genes: Linking dynamic expression changes to function. Nucleic Acids Research, 41 (5), 2817-2831. doi:10.1093/nar/gks1471
Peer Reviewed verified by ORBi

Schmitt, M. J., Philippidou, D., Reinsbach, S., Margue, C., Wienecke-Baldacchino, A., Nashan, D., Behrmann, I., & Kreis, S. (2012). Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells. Cell Communication and Signaling, 10. doi:10.1186/1478-811X-10-41
Peer Reviewed verified by ORBi

Reinsbach, S., Nazarov, P. V., Philippidou, D., Schmitt, M., Wienecke, A., Muller, A., Vallar, L., Behrmann, I., & Kreis, S. (2012). Dynamic regulation of microRNA expression following interferonγ- induced gene transcription. RNA Biology, 9 (7), 987-989. doi:10.4161/rna.20494
Peer Reviewed verified by ORBi

Philippidou, D., Schmitt, M., Moser, D., Margue, C., Nazarov, P. V., Muller, A., Vallar, L., Nashan, D., Behrmann, I., & Kreis, S. (2010). Signatures of MicroRNAs and selected MicroRNA target genes in human melanoma. Cancer Research, 70 (10), 4163-4173. doi:10.1158/0008-5472.CAN-09-4512
Peer Reviewed verified by ORBi

Kreis, S., Philippidou, D., Margue, C., & Behrmann, I. (10 May 2008). IL-24: a classic cytokine and/or a potential cure for cancer? Journal of Cellular and Molecular Medicine, 12 (6A), 2505-2510. doi:10.1111/j.1582-4934.2008.00372.x
Peer reviewed

Kreis, S., Philippidou, D., Margue, C., Rolvering, C., Haan, C., Dumoutier, L., Renauld, J.-C., & Behrmann, I. (2007). Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells. PLoS ONE, 2 (12), 1300. doi:10.1371/journal.pone.0001300
Peer Reviewed verified by ORBi

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