Profil

WURTH-MARGUE Christiane

University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)

ORCID
0009-0003-6357-8811
Main Referenced Co-authors
KREIS, Stephanie  (24)
BEHRMANN, Iris  (14)
PHILIPPIDOU, Demetra  (13)
HAAN, Claude  (7)
KOZAR, Ines  (6)
Main Referenced Keywords
melanoma (6); Humans (5); Melanoma (4); Animals (3); cancer (3);
Main Referenced Unit & Research Centers
Department of Life Sciences and Medicine (2)
ULHPC - University of Luxembourg: High Performance Computing (2)
University of Luxembourg (2)
Life Science Research Unit-University of Luxembourg (1)
University of Lausanne (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (27)
Oncology (1)
Life sciences: Multidisciplinary, general & others (1)

Publications (total 29)

The most downloaded
435 downloads
Kozar, I., Margue, C., Rothengatter, S., Haan, C., & Kreis, S. (15 February 2019). Many ways to resistance: How melanoma cells evade targeted therapies. Biochimica et Biophysica Acta - Reviews on Cancer, 1871 (2), 313-322. doi:10.1016/j.bbcan.2019.02.002 https://hdl.handle.net/10993/38857

The most cited

216 citations (Scopus®)

Pecheur, I., Peyruchaud, O., Serre, C.-M., Guglielmi, J., Voland, C., Bourre, F., Margue, C., Cohen-Solal, M., Buffet, A., Kieffer, N., & Clezardin, P. (2002). Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone. FASEB Journal, 16 (10), 1266-8. doi:10.1096/fj.01-0911fje https://hdl.handle.net/10993/23944

GUREGHIAN, V., HERBST, H., KOZAR, I., MIHAJLOVIC, K., Malod-Dognin, N., Ceddia, G., ANGELI, C., WURTH-MARGUE, C., RANDIC, T., PHILIPPIDOU, D., TETSI NOMIGNI, M., HEMEDAN, A., TRANCHEVENT, L.-C., LONGWORTH, J., Bauer, M., BADKAS, A., GAIGNEAUX, A., Muller, A., OSTASZEWSKI, M., ... KREIS, S. (October 2023). A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma. Cancer Gene Therapy, 30 (10), 1330 - 1345. doi:10.1038/s41417-023-00640-z
Peer Reviewed verified by ORBi

Rigg, E., Wang, J., Xue, Z., Lunavat, T. R., Liu, G., Hoang, T., Parajuli, H., Han, M., Bjerkvig, R., Nazarov, P. V., Nicot, N., KREIS, S., WURTH-MARGUE, C., TETSI NOMIGNI, M., Utikal, J., Miletic, H., Sundstrøm, T., Ystaas, L. A. R., Li, X., & Thorsen, F. (October 2023). Inhibition of extracellular vesicle-derived miR-146a-5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes. Journal of Extracellular Vesicles, 12 (10), 12363. doi:10.1002/jev2.12363
Peer Reviewed verified by ORBi

Bintener, T., Pires Pacheco, M. I., Philippidou, D., Margue, C., Kishk, A., Del Mistro, G., Di Leo, L., Moscardo Garcia, M., Halder, R., Sinkkonen, L., De Zio, D., Kreis, S., Kulms, D., & Sauter, T. (26 July 2023). Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma. Cell Death and Disease, 14 (468). doi:10.1038/s41419-023-05955-1
Peer reviewed

Randic, T., Kozar, I., Margue, C., Utikal, J., & Kreis, S. (29 May 2021). NRAS mutant melanoma: Towards better therapies. Cancer Treatment Reviews, 99. doi:10.1016/j.ctrv.2021.102238
Peer Reviewed verified by ORBi

Kozar, I., Philippidou, D., Margue, C., Gay, L., Renne, R., & Kreis, S. (2021). Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells. Cancers. doi:10.3390/cancers13051096
Peer Reviewed verified by ORBi

Kirchmeyer, M., Servais, F., Ginolhac, A., Nazarov, P. V., Margue, C., Philippidou, D., Nicot, N., Behrmann, I., Haan, C., & Kreis, S. (2020). Systematic transcriptional profiling of responses to STAT1- and STAT3- activating cytokines in different cancer types. Journal of Molecular Biology. doi:10.1016/j.jmb.2020.09.011
Peer Reviewed verified by ORBi

Walbrecq, G., Margue, C., Behrmann, I., & Kreis, S. (2020). Distinct Cargos of Small Extracellular Vesicles Derived from Hypoxic Cells and Their Effect on Cancer Cells. International Journal of Molecular Sciences. doi:10.3390/ijms21145071
Peer Reviewed verified by ORBi

Walbrecq, G., Lecha, O., Gaigneaux, A., Fougeras, M. R., Philippidou, D., Margue, C., Tetsi Nomigni, M., Bernardin, F., Dittmar, G., Behrmann, I., & Kreis, S. (2020). Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles. Cancers. doi:10.3390/cancers12030692
Peer Reviewed verified by ORBi

Kozar, I., Margue, C., Rothengatter, S., Haan, C., & Kreis, S. (15 February 2019). Many ways to resistance: How melanoma cells evade targeted therapies. Biochimica et Biophysica Acta - Reviews on Cancer, 1871 (2), 313-322. doi:10.1016/j.bbcan.2019.02.002
Peer Reviewed verified by ORBi

Margue, C., Philippidou, D., Kozar, I., Cesi, G., Felten, P., Kulms, D., Letellier, E., Haan, C., & Kreis, S. (February 2019). Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells. Journal of Experimental and Clinical Cancer Research, 38 (1). doi:10.1186/s13046-019-1038-x
Peer Reviewed verified by ORBi

Rolvering, C., Zimmer, A. D., Ginolhac, A., Margue, C., Kirchmeyer, M., Servais, F., Hermanns, H. M., Hergovits, S., Nazarov, P. V., Nicot, N., Kreis, S., Haan, S., Behrmann, I., & Haan, C. (2018). The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by a-PD-L1 or a-IL6 antibodies. Journal of Leukocyte Biology, 104, 969-985. doi:10.1002/JLB.MA1217-495R
Peer Reviewed verified by ORBi

Kreis, S., Kozar, I., Cesi, G., Margue, C., & Philippidou, D. (2017). Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells. Biochimica et Biophysica Acta. doi:10.1016/j.bbagen.2017.04.005
Peer reviewed

Heulot, M., Chevalier, N., Puyal, J., Margue, C., Michel, S., Kreis, S., Kulms, D., Barras, D., Nahimana, A., & Widmann, C. (27 September 2016). The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. Oncotarget, 7 (39). doi:10.18632/oncotarget.11841
Peer Reviewed verified by ORBi

Cesi, G., Walbrecq, G., Margue, C., & Kreis, S. (10 June 2016). Transferring intercellular signals and traits between cancer cells: extracellular vesicles as "homing pigeons". Cell Communication and Signaling, 14 (1), 13. doi:10.1186/s12964-016-0136-z
Peer Reviewed verified by ORBi

Behrmann, I., Margue, C., & Kreis, S. (2015). Circulating microRNAs as candidate biomarkers for the surveillance of melanoma patients. EBioMedicine. doi:10.1016/j.ebiom.2015.07.015
Peer reviewed

Margue, C., Reinsbach, S., Philippidou, D., Beaume, N., Walters, C., Schneider, J., Nashan, D., Behrmann, I., & Kreis, S. (2015). Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Oncotarget, 6 (14), 12110-27. doi:10.18632/oncotarget.3661
Peer Reviewed verified by ORBi

Margue, C., Philippidou, D., Reinsbach, S., Schmitt, M., Behrmann, I., & Kreis, S. (05 September 2013). New Target Genes of MITF-Induced microRNA-211 Contribute to Melanoma Cell Invasion. PLoS ONE, 8 (9). doi:10.1371/journal.pone.0073473
Peer Reviewed verified by ORBi

Schmitt, M., Margue, C., Behrmann, I., & Kreis, S. (2012). MiRNA-29: A microRNA family with tumor-suppressing and immune-modulating properties. Current Molecular Medicine, 13 (4), 572-585. doi:10.2174/1566524011313040009
Peer Reviewed verified by ORBi

Schmitt, M. J., Philippidou, D., Reinsbach, S., Margue, C., Wienecke-Baldacchino, A., Nashan, D., Behrmann, I., & Kreis, S. (2012). Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells. Cell Communication and Signaling, 10. doi:10.1186/1478-811X-10-41
Peer Reviewed verified by ORBi

Margue, C., & Kreis, S. (2010). IL-24: Physiological and supraphysiological effects on normal and malignant cells. Current Medicinal Chemistry, 17 (29), 3318-3326. doi:10.2174/092986710793176311
Peer reviewed

Philippidou, D., Schmitt, M., Moser, D., Margue, C., Nazarov, P. V., Muller, A., Vallar, L., Nashan, D., Behrmann, I., & Kreis, S. (2010). Signatures of MicroRNAs and selected MicroRNA target genes in human melanoma. Cancer Research, 70 (10), 4163-4173. doi:10.1158/0008-5472.CAN-09-4512
Peer Reviewed verified by ORBi

Kreis, S., Philippidou, D., Margue, C., & Behrmann, I. (10 May 2008). IL-24: a classic cytokine and/or a potential cure for cancer? Journal of Cellular and Molecular Medicine, 12 (6A), 2505-2510. doi:10.1111/j.1582-4934.2008.00372.x
Peer reviewed

Haan, S., Margue, C., Engrand, A., Rolvering, C., Schmitz-Van de Leur, H., Heinrich, P. C., Behrmann, I., & Haan, C. (2008). Dual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation. Journal of Immunology, 180 (2), 998-1007. doi:10.4049/jimmunol.180.2.998
Peer Reviewed verified by ORBi

Kreis, S., Philippidou, D., Margue, C., Rolvering, C., Haan, C., Dumoutier, L., Renauld, J.-C., & Behrmann, I. (2007). Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells. PLoS ONE, 2 (12), 1300. doi:10.1371/journal.pone.0001300
Peer Reviewed verified by ORBi

Schmitz, M., Grignard, G., Margue, C., Dippel, W., Capesius, C., Mossong, J., Nathan, M., Giacchi, S., Scheiden, R., & Kieffer, N. (2007). Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis. International Journal of Cancer, 120 (6), 1284-92. doi:10.1002/ijc.22359
Peer Reviewed verified by ORBi

Haan, C., Kreis, S., Margue, C., & Behrmann, I. (November 2006). Jaks and cytokine receptors - an intimate relationship. Biochemical Pharmacology, 72 (11), 1538-46. doi:10.1016/j.bcp.2006.04.013
Peer reviewed

Pecheur, I., Peyruchaud, O., Serre, C.-M., Guglielmi, J., Voland, C., Bourre, F., Margue, C., Cohen-Solal, M., Buffet, A., Kieffer, N., & Clezardin, P. (2002). Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone. FASEB Journal, 16 (10), 1266-8. doi:10.1096/fj.01-0911fje
Peer Reviewed verified by ORBi

Margue, C., Bernasconi, M., Barr, F., & Schäfer, B. (08 June 2000). Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR. Oncogene, 19 (25), 2921. doi:10.1038/sj.onc.1203607
Peer Reviewed verified by ORBi

Filser, N., Margue, C., & Richter, C. (1997). Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs. Biochemical and Biophysical Research Communications, 233 (1), 102-7. doi:10.1006/bbrc.1997.6409
Peer reviewed

Contact ORBilu