KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19 Peer reviewed |
ACENCIO, M. L., OSTASZEWSKI, M., MAZEIN, A., Rosenstiel, P., Aden, K., Mishra, N., Andersen, V., Sidiropoulos, P., Banos, A., Filia, A., Rahmouni, S., Finckh, A., GU, W., SCHNEIDER, R., & SATAGOPAM, V. (01 November 2023). The SYSCID map: a graphical and computational resource of molecular mechanisms across rheumatoid arthritis, systemic lupus erythematosus and inflammatory bowel disease. Frontiers in Immunology, 14. doi:10.3389/fimmu.2023.1257321 Peer Reviewed verified by ORBi |
GUREGHIAN, V., HERBST, H., KOZAR, I., MIHAJLOVIC, K., Malod-Dognin, N., Ceddia, G., ANGELI, C., WURTH-MARGUE, C., RANDIC, T., PHILIPPIDOU, D., TETSI NOMIGNI, M., HEMEDAN, A., TRANCHEVENT, L.-C., LONGWORTH, J., Bauer, M., BADKAS, A., GAIGNEAUX, A., Muller, A., OSTASZEWSKI, M., ... KREIS, S. (October 2023). A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma. Cancer Gene Therapy, 30 (10), 1330 - 1345. doi:10.1038/s41417-023-00640-z Peer Reviewed verified by ORBi |
HANSEN, B., LACZNY, C. C., AHO, V., Frachet-Bour, A., Habier, J., OSTASZEWSKI, M., Michalsen, A., Hanslian, E., Koppold, D. A., Hartmann, A. M., Steckhan, N., Mollenhauer, B., Schade, S., RUMP, K., SCHNEIDER, J., & WILMES, P. (18 August 2023). Protocol for a multicentre cross-sectional, longitudinal ambulatory clinical trial in rheumatoid arthritis and Parkinson's disease patients analysing the relation between the gut microbiome, fasting and immune status in Germany (ExpoBiome). BMJ Open, 13 (8), 071380. doi:10.1136/bmjopen-2022-071380 Peer Reviewed verified by ORBi |
Gawron, P., Smula, E., SCHNEIDER, R., & OSTASZEWSKI, M. (February 2023). Exploration and comparison of molecular mechanisms across diseases using MINERVA Net. Protein Science: A Publication of the Protein Society, 32 (2), 4565. doi:10.1002/pro.4565 Peer Reviewed verified by ORBi |
HEMEDAN, A., SCHNEIDER, R., & OSTASZEWSKI, M. (2023). Applications of Boolean modeling to study the dynamics of a complex disease and therapeutics responses. Frontiers in bioinformatics, 3, 1189723. doi:10.3389/fbinf.2023.1189723 Peer reviewed |
MAZEIN, A., ACENCIO, M. L., BALAUR, I.-A., Rougny, A., WELTER, D., Niarakis, A., Ramirez Ardila, D., Dogrusoz, U., GAWRON, P., SATAGOPAM, V., GU, W., KREMER, A., SCHNEIDER, R., & OSTASZEWSKI, M. (2023). A guide for developing comprehensive systems biology maps of disease mechanisms: planning, construction and maintenance. Frontiers in Bioinformatics, 3, 1197310. doi:10.3389/fbinf.2023.1197310 Peer reviewed |
Gawron, P., Hoksza, D., Piñero, J., Peña-Chilet, M., Esteban-Medina, M., Fernandez-Rueda, J. L., Colonna, V., Smula, E., HEIRENDT, L., Ancien, F., GROUES, V., SATAGOPAM, V., SCHNEIDER, R., Dopazo, J., Furlong, L. I., & OSTASZEWSKI, M. (2023). Visualization of automatically combined disease maps and pathway diagrams for rare diseases. Frontiers in Bioinformatics, 3, 1101505. doi:10.3389/fbinf.2023.1101505 Peer reviewed |
Corbett, M., Ramessur, R., Marshall, D., ACENCIO, M. L., OSTASZEWSKI, M., Barbosa, I. A., Dand, N., Di Meglio, P., Haddad, S., Jensen, A. H. M., Koopmann, W., Mahil, S. K., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Barker, J. N., ... BIOMAP consortium. (October 2022). Biomarkers of systemic treatment response in people with psoriasis: a scoping review. British Journal of Dermatology, 187 (4), 494 - 506. doi:10.1111/bjd.21677 Peer Reviewed verified by ORBi |
Ramessur, R., Corbett, M., Marshall, D., ACENCIO, M. L., Barbosa, I. A., Dand, N., Di Meglio, P., Haddad, S., Jensen, A. H. M., Koopmann, W., Mahil, S. K., OSTASZEWSKI, M., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Ndlovu, M., ... BIOMAP consortium. (October 2022). Biomarkers of disease progression in people with psoriasis: a scoping review. British Journal of Dermatology, 187 (4), 481 - 493. doi:10.1111/bjd.21627 Peer Reviewed verified by ORBi |
Wilmes, P., Martin-Gallausiaux, C., Ostaszewski, M., Aho, V., Novikova, P., Laczny, C. C., & Schneider, J. (14 September 2022). The gut microbiome molecular complex in human health and disease. Cell Host and Microbe, 30 (9), 1201-1206. doi:10.1016/j.chom.2022.08.016 Peer Reviewed verified by ORBi |
Aho, V., Ostaszewski, M., Martin-Gallausiaux, C., Laczny, C. C., Schneider, J., & Wilmes, P. (14 September 2022). SnapShot: The Expobiome Map. Cell Host and Microbe, 30 (9), 1340. doi:10.1016/j.chom.2022.08.015 Peer Reviewed verified by ORBi |
Garcia, P., Wemheuer, W., Uriarte, O., Michelucci, A., Masuch, A., Brioschi, S., Weihofen, A., Koncina, E., Coowar, D., Heurtaux, T., Glaab, E., Balling, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., ... Buttini, M. (2022). Neurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease. Glia. doi:10.1002/glia.24149 Peer Reviewed verified by ORBi |
Martins Dos Santos, V., Anton, M., Szomolay, B., OSTASZEWSKI, M., Arts, I., Benfeitas, R., Dominguez Del Angel, V., Ferk, P., Fey, D., Goble, C., Golebiewski, M., Gruden, K., Heil, K. F., Hermjakob, H., Kahlem, P., Klapa, M. I., Koehorst, J., Kolodkin, A., Kutmon, M., ... Hancock, J. M. (2022). Systems Biology in ELIXIR: modelling in the spotlight. F1000Research, 11, 1265. doi:10.12688/f1000research.126734.1 Peer Reviewed verified by ORBi |
Pereira, C., MAZEIN, A., Farinha, C. M., Gray, M. A., Kunzelmann, K., OSTASZEWSKI, M., BALAUR, I.-A., Amaral, M. D., & Falcao, A. O. (15 November 2021). CyFi-MAP: an interactive pathway-based resource for cystic fibrosis. Scientific Reports, 11 (1), 22223. doi:10.1038/s41598-021-01618-3 Peer Reviewed verified by ORBi |
MAZEIN, A., Rougny, A., Karr, J. R., Saez-Rodriguez, J., OSTASZEWSKI, M., & SCHNEIDER, R. (02 September 2021). Reusability and composability in process description maps: RAS-RAF-MEK-ERK signalling. Briefings in Bioinformatics, 22 (5). doi:10.1093/bib/bbab103 Peer Reviewed verified by ORBi |
MAZEIN, A., Ivanova, O., BALAUR, I.-A., OSTASZEWSKI, M., Berzhitskaya, V., Serebriyskaya, T., Ligon, T., Hasenauer, J., De Meulder, B., Overall, R. W., Roy, L., Knowles, R. G., Wheelock, C. E., Dahlen, S.-E., Chung, K. F., Adcock, I. M., Roberts, G., Djukanovic, R., Pellet, J., ... eTRIKS Consortium. (March 2021). AsthmaMap: An interactive knowledge repository for mechanisms of asthma. Journal of Allergy and Clinical Immunology, 147 (3), 853 - 856. doi:10.1016/j.jaci.2020.11.032 Peer Reviewed verified by ORBi |
Rian, K., Esteban-Medina, M., Hidalgo, M. R., Çubuk, C., Falco, M. M., Loucera, C., Gunyel, D., OSTASZEWSKI, M., Peña-Chilet, M., & Dopazo, J. (21 January 2021). Mechanistic modeling of the SARS-CoV-2 disease map. BioData Mining, 14 (1), 5. doi:10.1186/s13040-021-00234-1 Peer Reviewed verified by ORBi |
Ostaszewski, M., Niarakis, A., Mazein, A., Kuperstein, I., Phair, R., Orta-Resendiz, A., Singh, V., Aghamiri, S. S., Acencio, M. L., Glaab, E., Ruepp, A., Fobo, G., Montrone, C., Brauner, B., Frishman, G., Monraz Gómez, L. C., Somers, J., Hoch, M., Kumar Gupta, S., ... Schneider, R. (2021). COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. Molecular Systems Biology, 17 (10), 10387. doi:10.15252/msb.202110387 Peer Reviewed verified by ORBi |
Vega Moreno, C. G., Groues, V., Ostaszewski, M., Satagopam, V., & Schneider, R. (04 September 2020). BioKC: a platform for quality controlled curation and annotation of systems biology models [Paper presentation]. European Conference on Computational Biology. doi:10.5281/zenodo.4033071 |
Ostaszewski, M., Mazein, A., Gillespie, M., Kuperstein, I., Niarakis, A., Hermjakob, H., Pico, A., Willinghagen, E., Evelo, C., Hasenauer, J., Schreiber, F., Dräger, A., Demir, E., Wolkenhauer, O., Furlong, L., Barillot, E., Dopazo, J., Orta-Resendiz, A., Messina, F., ... Schneider, R. (2020). COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms. Scientific Data. doi:10.1038/s41597-020-0477-8 Peer reviewed |
HEMEDAN, A., Abd Elaziz, M., Jiao, P., Alavi, A. H., Bahgat, M., OSTASZEWSKI, M., SCHNEIDER, R., Ghazy, H. A., Ewees, A. A., & Lu, S. (19 March 2020). Prediction of the Vaccine-derived Poliovirus Outbreak Incidence: A Hybrid Machine Learning Approach. Scientific Reports, 10 (1), 5058. doi:10.1038/s41598-020-61853-y Peer Reviewed verified by ORBi |
Krüger, R., Balling, R., Antony, P., Kondratyeva, O., Ostaszewski, M., Baumuratov, A., Grossmann, D., Mommaerts, K., Sokolowska, K., Longhino, L., Poulain, J. F., & Diederich, N. J. (2020). Fibroblast mitochondria in idiopathic Parkinson’s disease display morphological changes and enhanced resistance to depolarization. Scientific Reports. doi:10.1038/s41598-020-58505-6 Peer Reviewed verified by ORBi |
Vega Moreno, C. G., Groues, V., Ostaszewski, M., Schneider, R., & Satagopam, V. (2020). BioKC: a collaborative platform for systems biology model curation and annotation. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/44411. doi:10.1101/2020.10.01.322438 |
Singh, V., Kalliolias, G. D., OSTASZEWSKI, M., Veyssiere, M., Pilalis, E., Gawron, P., MAZEIN, A., Bonnet, E., Petit-Teixeira, E., & Niarakis, A. (01 January 2020). RA-map: building a state-of-the-art interactive knowledge base for rheumatoid arthritis. Database: The Journal of Biological Databases and Curation, 2020. doi:10.1093/database/baaa017 Peer Reviewed verified by ORBi |
Hoksza, D., Gawron, P., Ostaszewski, M., Hausenauer, J., & Schneider, R. (2019). Closing the gap between formats for storing layout information in systems biology. Briefings in Bioinformatics. doi:10.1093/bib/bbz067 Peer Reviewed verified by ORBi |
Abd Elaziz, M., Hemedan, A., Ostaszewski, M., Schneider, R., & Lu, S. (2019). Optimization ACE inhibition activity in hypertension based on random vector functional link and sine-cosine algorithm. Chemometrics and Intelligent Laboratory Systems. doi:10.1016/j.chemolab.2019.05.009 Peer Reviewed verified by ORBi |
Nielsen, S. S., Ostaszewski, M., McGee, F., Hoksza, D., & Zorzan, S. (2019). Machine Learning to Support the Presentation of Complex Pathway Graphs. IEEE/ACM Transactions on Computational Biology and Bioinformatics. doi:10.1109/TCBB.2019.2938501 Peer Reviewed verified by ORBi |
Hoksza, D., Gawron, P., Ostaszewski, M., Smula, E., & Schneider, R. (2019). MINERVA API and plugins: opening molecular network analysis and visualization to the community. Bioinformatics. doi:10.1093/bioinformatics/btz286 Peer reviewed |
Hoksza, D., Gawron, P., Ostaszewski, M., & Schneider, R. (2018). MolArt: a molecular structure annotation and visualization tool. Bioinformatics. doi:10.1093/bioinformatics/bty489 Peer reviewed |
Ostaszewski, M., Kieffer, E., Danoy, G., Schneider, R., & Bouvry, P. (2018). Clustering approaches for visual knowledge exploration in molecular interaction networks. BMC Bioinformatics, 19 (1), 308. doi:10.1186/s12859-018-2314-z Peer Reviewed verified by ORBi |
Curi, M. E., Carozzi, L., Massobrio, R., Nesmachnow, S., Danoy, G., Ostaszewski, M., & Bouvry, P. (2018). Single and Multiobjective Evolutionary Algorithms for Clustering Biomedical Information with Unknown Number of Clusters. In Bioinspired Optimization Methods and Their Applications. Cham, Unknown/unspecified: Springer International Publishing. Peer reviewed |
Ostaszewski, M., Gebel, S., Kuperstein, I., Mazein, A., Zinovyev, A., Dogrusoz, U., Hasenauer, J., Fleming, R. M., Le Novere, N., Gawron, P., Ligon, T., Niarakis, A., Nickerson, D., Weindl, D., Balling, R., Barillot, E., Auffray, C., & Schneider, R. (2018). Community-driven roadmap for integrated disease maps. Briefings in Bioinformatics. doi:10.1093/bib/bby024 Peer Reviewed verified by ORBi |
Mazein, A., Ostaszewski, M., Kuperstein, I., Watterson, S., Le Novere, N., Lefaudeux, D., De Meulder, B., Pellet, J., Balaur, I., Saqi, M., Nogueira, M. M., He, F., Parton, A., Lemonnier, N., Gawron, P., Gebel, S., Hainaut, P., Ollert, M., Dogrusoz, U., ... Auffray, C. (2018). Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms. NPJ Systems Biology and Applications, 4, 21. doi:10.1038/s41540-018-0059-y Peer Reviewed verified by ORBi |
Singh, V., Ostaszewski, M., Kalliolias, G. D., Chiocchia, G., Olaso, R., Petit-Teixeira, E., Helikar, T., & Niarakis, A. (2017). Computational Systems Biology Approach for the Study of Rheumatoid Arthritis: From a Molecular Map to a Dynamical Model. Genomics and Computational Biology. doi:10.18547/gcb.2018.vol4.iss1.e100050 Peer reviewed |
Changaival, B., Danoy, G., Ostaszewski, M., Lavangnananda, K., & Bouvry, P. (2016). Metaheuristic Based Clustering Algorithms for Biological Hypergraphs. In Proceedings of META’2016, 6th International Conference on Metaheuristics and Nature Inspired computing (pp. 364-366). Peer reviewed |
Gawron, P., Ostaszewski, M., Satagopam, V., Gebel, S., Mazein, A., Kuzma, M., Zorzan, S., McGee, F., Otjacques, B., Balling, R., & Schneider, R. (2016). MINERVA—a platform for visualization and curation of molecular interaction networks. NPJ Systems Biology and Applications. doi:10.1038/npjsba.2016.20 Peer Reviewed verified by ORBi |
Baumuratov, A.* , Antony, P.* , Ostaszewski, M., He, F., Salamanca Mino, L., Antunes, L., Weber, J., Longhino, L., Derkinderen, P., Koopman, W. J. H., & Diederich, N. J. (2016). Enteric neurons from Parkinson's disease patients display ex vivo aberrations in mitochondrial structure. Scientific Reports, 6, 33117. doi:10.1038/srep33117 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Satagopam, V., Gu, W., Eifes, S., Gawron, P., Ostaszewski, M., Gebel, S., Barbosa-Silva, A., Balling, R., & Schneider, R. (2016). Integration and Visualization of Translational Medicine Data for Better Understanding of Human Diseases. Big Data, 4 (2), 97-108. doi:10.1089/big.2015.0057 Peer reviewed |
Ostaszewski, M., Skupin, A., & Balling, R. (2016). Neurological Diseases from a Systems Medicine Point of View. Methods in Molecular Biology, 1386, 221-50. doi:10.1007/978-1-4939-3283-2_11 Peer Reviewed verified by ORBi |
Antony, P., Antunes, L., Frasquilho, S., Ostaszewski, M., Weber, J., Longhino, L., Baumuratov, A., Derkinderen, P., Balling, R., & Diederich, N. (June 2015). Staining for unphosphorylated alpha-synuclein in the colon mucosa. No difference between patients with Parkinson's disease and healthy controls [Paper presentation]. 19th International Congress of Parkinson's Disease and Movement. |
Antony, P., Boyd, O., Trefois, C., Ammerlaan, W., Ostaszewski, M., Baumuratov, A. S., Longhino, L., Antunes, L., Koopman, W., Balling, R., & Diederich, N. J. (2015). Platelet mitochondrial membrane potential in Parkinson's disease. Annals of Clinical and Translational Neurology, 2 (1), 67-73. doi:10.1002/acn3.151 Peer Reviewed verified by ORBi |
Grevisse, C., Muller, I. W., Jimenez Laredo, J. L., Ostaszewski, M., Danoy, G., & Bouvry, P. (2014). Visualization and Classification of Protein Secondary Structures using Self-Organizing Maps. In IEEE Symposium Series on Computational Intelligence (IEEE SSCI 2014). Peer reviewed |
Antony, P., Boyd, O., Trefois, C., Ostaszewski, M., Baumuratov, A., Balling, R., & Diederich, N. (12 June 2014). Analysis of mitochondrial membrane potential in idiopathic Parkinson's disease: A case-control study [Paper presentation]. 18th International Congress of Parkinson's Disease and Movement. |
Antony, P., Ostaszewski, M., Gawron, P., Trefois, C., Fujita, K. A., Mosch, S., & Balling, R. (12 June 2014). Curation of complex molecular pathways of Parkinson's disease as a collaborative scientific community effort [Paper presentation]. 18th International Congress of Parkinson's Disease and Movement. |
Fujita, K. A., Ostaszewski, M., Matsuoka, Y., Ghosh, S., Glaab, E., Trefois, C., Crespo, I., Perumal, T. M., Jurkowski, W., Antony, P., Diederich, N., Buttini, M., Kodama, A., Satagopam, V., Eifes, S., del Sol Mesa, A., Schneider, R., Kitano, H., & Balling, R. (2014). Integrating Pathways of Parkinson's Disease in a Molecular Interaction Map. Molecular Neurobiology. doi:10.1007/s12035-013-8489-4 Peer Reviewed verified by ORBi |
Ostaszewski, M., Fujita, K., Matsuoka, Y., Ghosh, S., Glaab, E., Trefois, C., Crespo, I., Perumal, T. M., Jurkowski, W., Antony, P., Diederich, N., Buttini, M., Kolodkin, A., Kodama, A., Satagopam, V., Biryukov, M., Eifes, S., del Sol Mesa, A., Schneider, R., ... Balling, R. (09 March 2013). The Parkinson's Disease Map: A Framework for Integration, Curation and Exploration of Disease-related Pathways [Poster presentation]. The 11th International Conference on Alzheimer's & Parkinson's Diseases, Florence, Italy. |
Trefois, C., Fujita, A. K., Ostaszewski, M., Matsuoka, Y., Ghosh, S., Glaab, E., Crespo, I., Perumal, T. M., Jurkowski, W., Antony, P., Diederich, N., Buttini, M., Kodama, A., Satagopam, V., Eifes, S., del Sol Mesa, A., Schneider, R., Kitano, H., & Balling, R. (August 2012). Constructing a comprehensive map of Parkinson’s disease to elucidate underlying mechanisms of its multifaceted molecular pathology [Poster presentation]. The 13th International Conference on Systems Biology. |
Ostaszewski, M., Eifes, S., & del Sol Mesa, A. (2012). Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human. PLoS ONE, 7 (5), 36488. doi:10.1371/journal.pone.0036488 Peer Reviewed verified by ORBi |
Ostaszewski, M. (2010). On capturing vital properties of denial of service attacks using metaheuristic approaches [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/15434 |
Ostaszewski, M., Bouvry, P., & Seredynski, F. (2009). Multiobjective Classification with moGEP: An Application in the Network Traffic Domain. GECCO '09: Proceedings of the 11th Annual conference on Genetic and evolutionary computation, 635–642. doi:10.1145/1569901.1569989 Peer reviewed |
Ostaszewski, M., Bouvry, P., & Seredynski, F. (2008). Adaptive and Dynamic Intrusion Detection by Means of Idiotypic Networks Paradigm. The 21th IEEE International Parallel and Distributed Processing Symposium (IPDPS), NIDISC Workshop, 1–8. doi:10.1109/IPDPS.2008.4536377 Peer reviewed |
Ostaszewski, M., Bouvry, P., & Seredynski, F. (2008). An Approach to Intrusion Detection by Means of Idiotypic Networks Paradigm. IEEE World Congress on Computational Intelligence, WCCI 2008, Congress on Evolutionary Computation CEC 2008, Honk-Kong, June. doi:10.1109/CEC.2008.4631077 Peer reviewed |
Varrette, S., Ostaszewski, M., & Bouvry, P. (2008). Nature inspired Algorithm-Based Fault Tolerance on Global Computing Platforms. Application to Symbolic Regression. International Conference on Metaheuristics and Nature Inspired Computing (META'08). Peer reviewed |
Ostaszewski, M., Seredynski, F., & Bouvry, P. (2007). Coevolutionary-based Mechanisms for Network Anomaly Detection. Journal of Mathematical Modelling and Algorithms, 6 (3), 411-431. doi:10.1007/s10852-007-9061-x Peer reviewed |