Profil

GALAS David J

Main Referenced Co-authors
BALLING, Rudolf  (7)
Glusman, Gustavo (6)
MAY, Patrick  (6)
Wang, Kai (6)
HOOD, Leroy  (5)
Main Referenced Keywords
gene network (2); Aneuploidy (1); Automated Image Analysis (1); Base Sequence (1); Biological networks (1);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) (21)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (7)
ULHPC - University of Luxembourg: High Performance Computing (4)
Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group) (3)
LCSB (1)
Main Referenced Disciplines
Life sciences: Multidisciplinary, general & others (13)
Genetics & genetic processes (3)
Microbiology (3)
Physical, chemical, mathematical & earth Sciences: Multidisciplinary, general & others (3)
Human health sciences: Multidisciplinary, general & others (2)

Publications (total 27)

The most downloaded
832 downloads
Krishna, A., Biryukov, M., Trefois, C., Antony, P., Hussong, R., Lin, J., Heinäniemi, M., Glusman, G., Köglsberger, S., Boyd, O., van den Berg, B. H. J., Linke, D., Huang, D., Wang, K., Hood, L., Tholey, A., Schneider, R., Galas, D. J., Balling, R., & May, P. (20 December 2014). Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease. BMC Genomics, 15 (1154). doi:10.1186/1471-2164-15-1154 https://hdl.handle.net/10993/19379

The most cited

542 citations (Scopus®)

Wang, K., Yuan, Y., Cho, J. H., McClarty, S., Baxter, D., & Galas, D. J. (31 July 2012). Comparing the MicroRNA Spectrum between Serum and Plasma. PLoS ONE, 7 (7), 41561. doi:10.1371/journal.pone.0041561 https://hdl.handle.net/10993/16035

Ameziane, N., May, P., Van de Vrugt, H. J., Van Rossum-Fikkert, S. E., Ristic, D., Williams, G. J., Balk, J., Rockx, D., Li, H., Rooimans, M. A., Oostra, A. B., Velleuer, E., Dietrich, R., Bleijerveld, O. B., Altelaar, A. F. M., Meijers-Heijboer, H., Joenje, H., Glusman, G., Roach, J. C., ... Dorsman, J. C. (18 December 2015). A novel Fanconi anemia subtype associated with a dominant-negative mutation in RAD51. Nature Communications, 6 (8829). doi:10.1038/ncomms9829
Peer Reviewed verified by ORBi

Ghosal, A., Upadhyaya, B. B., Fritz, J., Heintz, A., Desai, M., Dilimulati, Y., Huang, D., Baumuratov, A., Wang, K., Galas, D. J., & Wilmes, P. (2015). The extracellular RNA complement of Escherichia coli. MicrobiologyOpen. doi:10.1002/mbo3.235
Peer Reviewed verified by ORBi

Sakhanenko, N. A., & Galas, D. J. (2015). Biological data analysis as an information theory problem: multivariable dependence measures and the shadows algorithm. Journal of Computational Biology, 22 (11), 1005-1024. doi:10.1089/cmb.2015.0051
Peer Reviewed verified by ORBi

Laurent, L., Abdel-Mageed, A., Adelson, P. D., Arango, J., Balaj, L., Breakefield, X., Carlson, E., Carter, B. S., Cavaller, B. M., Chen, C. C., Cocucci, E., Danielson, K., Courtright, A., Das, S., Elmageed, Z. Y. A., Enderle, D., Ezrin, A., Ferrer, M., Freedman, J., ... Gould, S. (2015). Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium. Journal of Extracellular Vesicles, 4, 1-18. doi:10.3402/jev.v4.26533

Krishna, A., Biryukov, M., Trefois, C., Antony, P., Hussong, R., Lin, J., Heinäniemi, M., Glusman, G., Köglsberger, S., Boyd, O., van den Berg, B. H. J., Linke, D., Huang, D., Wang, K., Hood, L., Tholey, A., Schneider, R., Galas, D. J., Balling, R., & May, P. (20 December 2014). Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease. BMC Genomics, 15 (1154). doi:10.1186/1471-2164-15-1154
Peer Reviewed verified by ORBi

Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J. R., de Kovel, C. G. F., Thiele, H., Konrad, K., Kawalia, A., Toliat, M. R., Sander, T., Ruschendorf, F., Caliebe, A., Nagel, I., Kohl, B., ... Lerche, H. (02 November 2014). Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. Nature Genetics, 46 (12), 1327-32. doi:10.1038/ng.3130
Peer Reviewed verified by ORBi

Eibelt, U., Trovato, A., Kloth, M., Gentz, E., Finke, R., Spranger, J., Galas, D. J., Weber, S., Wolf, C.-A., König, K., Arlt, W., Büttner, R., May, P., Allolio, B., & Schneider, J. (2014). Molecular and Clinical Evidence for an ARMC5 Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations are Associated with both Primary Macronodular Adrenal Hyperplasia and Meningioma. Journal of Clinical Endocrinology and Metabolism. doi:10.1210/jc.2014-2648
Peer reviewed

Ignac, T., Skupin, A., Sakhanenko, N. A., & Galas, D. J. (2014). Discovering pair-wise genetic interactions: an information theory-based approach. PLoS ONE, 9 (3), 92310. doi:10.1371/journal.pone.0092310
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Hu, H., Roach, J. C., Coon, H., Guthery, S. L., Voelkerding, K. V., Margraf, R. L., Durtschi, J. D., Tavtigian, S. V., Shankaracharya, Wu, W., Scheet, P., Wang, S., Xing, J., Glusman, G., Hubley, R., Li, H., Garg, V., Moore, B., Hood, L., ... Huff, C. D. (2014). A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data. Nature Biotechnology, 32 (7), 663-669. doi:10.1038/nbt.2895
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Wilkening, S., Lin, G., Fritsch, E. S., Tekkedil, M. M., Anders, S., Kuehn, R., Nguyen, M., Aiyar, R. S., Proctor, M., Sakhanenko, N. A., Galas, D. J., Gagneur, J., Deutschbauer, A., & Steinmetz, L. M. (2014). An evaluation of high-throughput approaches to QTL mapping in Saccharomyces cerevisiae. Genetics, 196 (3), 853-65. doi:10.1534/genetics.113.160291
Peer reviewed

Galas, D. J., Wilmes, P., & Wang, K. (2014). RNA in circulation: sources and functions of extracellular exogenous RNA in blood. In K. Nelson (Ed.), Encyclopedia of Metagenomics. New York, United States: SpringerReference. doi:10.1007/978-1-4614-6418-1_105-2
Peer reviewed

Dilimulati, Y., Heintz, A., Ghosal, A., Upadhyaya, B. B., Fritz, J., Laczny, C. C., May, P., Muller, E., Shah, P., Desai, M., Roume, H., Huang, D., Wang, K., Galas, D. J., & Wilmes, P. (October 2013). The exogenous RNA spectrum in human plasma and the gastrointestinal tract [Poster presentation]. 2nd International Systems Biomedicine Symposium, Belval, Luxembourg.

Antony, P., Krishna, A., May, P., Trefois, C., Boyd, O., Köglsberger, S., Baumuratov, A., Galas, D. J., & Balling, R. (2013). Differentiated SH-SY5Y Cells as PD Model for Mitochondrial Dysfunction: From Whole Genome Sequencing to an Educated Design of High-Throughput Experiments [Poster presentation]. The 11th International Conference on Alzheimer's & Parkinson's Diseases, Florence, Italy.

Wang, K., Yuan, Y., Cho, J.-H., Huang, D., Gray, L., Qin, S., & Galas, D. J. (2013). The spectrum of circulating RNA: A window into systems toxicology. Toxicological Sciences, 132 (2), 478–492. doi:10.1093/toxsci/kft014
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Wang, K., Yuan, Y., Cho, J. H., McClarty, S., Baxter, D., & Galas, D. J. (31 July 2012). Comparing the MicroRNA Spectrum between Serum and Plasma. PLoS ONE, 7 (7), 41561. doi:10.1371/journal.pone.0041561
Peer Reviewed verified by ORBi

Sakhanenko, N. A., & Galas, D. J. (08 March 2012). Probabilistic Logic Methods and Some Applications to Biology and Medicine. Journal of Computational Biology, 19 (3), 316-336. doi:10.1089/cmb.2011.0234
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Ignac, T., Sakhanenko, N. A., Skupin, A., & Galas, D. J. (2012). New methods for finding associations in large data sets: Generalizing the maximal information coefficient (MIC). Proceedings of the Ninth International Workshop on Computational Systems Biology, 39-42.
Peer reviewed

Ignac, T., Sakhanenko, N. A., & Galas, D. J. (2012). Complexity of Networks II: The Set Complexity of Edge-Colored Graphs. Complexity, 17 (5), 23-36. doi:10.1002/cplx.21383
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Wang, K., Li, H., Yuan, Y., Etheridge, A., Zhou, Y., Huang, D., Wilmes, P., & Galas, D. J. (2012). The complex exogenous RNA spectra in human plasma: an interface with human gut biota? PLoS ONE, 7 (12). doi:10.1371/journal.pone.0051009
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Chen, L. Y., Wei, K.-C., Huang, A. C.-Y., Wang, K., Huang, C.-Y., Yi, D., Tang, C. Y., Galas, D. J., & Hood, L. E. (2012). RNASEQR—a streamlined and accurate RNA-seq sequence analysis program. Nucleic Acids Research, 40 (6), 42. doi:10.1093/nar/gkr1248
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Ignac, T., Sakhanenko, N., & Galas, D. J. (2012). Relations between the set-complexity and the structure of graphs and their sub-graphs. EURASIP Journal on Bioinformatics and Systems Biology, 13. doi:10.1186/1687-4153-2012-13
Peer reviewed

Roach, J. C., Glusman, G., Hubley, R., Montsaroff, S. Z., Holloway, A. K., Mauldin, D. E., Srivastava, D., Garg, V., Pollard, K. S., Galas, D. J., Hood, L., & Smit, A. F. A. (18 August 2011). Chromosomal haplotypes by genetic phasing of human families. American Journal of Human Genetics, 89 (3), 382-397. doi:10.1016/j.ajhg.2011.07.023
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Simeonidis, V., Roach, J., Brunkow, M., Glusman, G., Reynolds, S., Balling, R., Hood, L., Galas, D. J., Wichmann, H.-E., Grimm, S., & Gelinas, R. (July 2011). Candidate mutations for early-onset lung cancer by family genome sequencing [Poster presentation]. ISMB/ECCB 2011 - 19th Annual International Conference on Intelligent Systems for Molecular Biology and 10th European Conference on Computational Biology, Vienna, Austria.

Moussay, E., Wang, K., Cho, J.-H., van Moer, K., Pierson, S., Paggetti, J., Nazarov, P. V., Palissot, V., Hood, L., Berchem, G., & Galas, D. J. (19 April 2011). MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 108 (16), 6573-6578. doi:10.1073/pnas.1019557108
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Ignac, T., Galas, D. J., & Sakhanenko, N. (2011). RELATION BETWEEN THE SET-COMPLEXITY OF A GRAPH AND ITS STRUCTURE. In Proceedings of the 8th International Workshop on Computational Systems Biology.
Peer reviewed

Bousquet, J., Anto, J. M., Sterk, P. J., Adcock, I. M., Chung, K. F., Roca, J., Agusti, A., Brightling, C., Cambon-Thomsen, A., Cesario, A., Abdelhak, S., Antonarakis, S. E., Avignon, A., Ballabio, A., Baraldi, E., Baranov, A., Bieber, T., Bockaert, J., Brahmachari, S., ... Auffray, C. (2011). Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Medicine, 3 (7), 43-47. doi:10.1186/gm259
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del Sol Mesa, A., Balling, R., Hood, L., & Galas, D. J. (2010). Diseases as network perturbations. Current Opinion in Biotechnology, 21 (4), 566-571. doi:10.1016/j.copbio.2010.07.010
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