Reservoirs of antimicrobial resistance in the context of One Health

[en] The emergence and spread of antimicrobial resistance (AMR) and resistant bacteria, are a global public health challenge. Through horizontal gene transfer, potential pathogens can acquire antimicrobial resistance genes (ARGs) that can subsequently be spread between human, animal, and environmental reservoirs. To understand the dissemination of ARGs and linked microbial taxa, it is necessary to map the resistome within different microbial reservoirs. By integrating knowledge on ARGs in the different reservoirs, the One Health approach is crucial to our understanding of the complex mechanisms and epidemiology of AMR. Here, we highlight the latest insights into the emergence and spread of AMR from the One Health perspective, providing a baseline of understanding for future scientific investigations into this constantly growing global health threat.

Disciplines :

Microbiology
Life sciences: Multidisciplinary, general & others

Author, co-author :

Despotovic, Milena ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

de Nies, Laura; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

Busi, Susheel Bhanu ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

Wilmes, Paul ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

External co-authors :

Language :

English

Title :

Reservoirs of antimicrobial resistance in the context of One Health

Publication date :

2023

Journal title :

Current Opinion in Microbiology

ISSN :

1369-5274

Publisher :

Elsevier, Netherlands

Volume :

Pages :

102291

Peer reviewed :

Peer Reviewed verified by ORBi

Focus Area :

Systems Biomedicine

Additional URL :

https://www.sciencedirect.com/science/article/pii/S1369527423000280

FnR Project :

FNR11823097 - Microbiomes In One Health, 2017 (01/09/2018-28/02/2025) - Paul Wilmes

Funders :

European Research Council (ERC-CoG 863664)
Luxembourg Government (CoVaLux programme)
Swiss National Science Foundation (CRSII5_180241)

Available on ORBilu :

since 22 April 2023

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