PDE6D Inhibitors with a New Design Principle Selectively Block K‑Ras Activity

Siddiqui, Farid A.; Alam, Catharina; Rosenqvist, Petja; Ora, Mikko; Sabt, Ahmed; Manoharan, Ganesh Babu; Bindu, Lakshman; Okutachi, Sunday Ojochegbe; Catillon, Marie; Taylor, Troy; Abdelhafez, Omaima M.; Lönnberg, Harri; Stephen, Andrew G.; Papageorgiou, Anastassios C.; Virta, Pasi; Abankwa, Daniel

doi:10.1021/acsomega.9b03639

Reference : PDE6D Inhibitors with a New Design Principle Selectively Block K‑Ras Activity


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/10993/41426

Title :	PDE6D Inhibitors with a New Design Principle Selectively Block K‑Ras Activity
Language :	English
Author, co-author :	Siddiqui, Farid A. [Turku Bioscience Centre, University of Turku and Åbo Akademi University]
	Alam, Catharina [Turku Bioscience Centre, University of Turku and Åbo Akademi University]
	Rosenqvist, Petja [University of Turku > Department of Chemistry]
	Ora, Mikko [University of Turku > Department of Chemistry]
	Sabt, Ahmed [National Research Centre, Egypt]
	Manoharan, Ganesh Babu [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit >]
	Bindu, Lakshman [Frederick National Laboratory for Cancer Research > NCI RAS Initiative]
	Okutachi, Sunday Ojochegbe [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit >]
	Catillon, Marie [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit >]
	Taylor, Troy [Frederick National Laboratory for Cancer Research > NCI RAS Initiative]
	Abdelhafez, Omaima M. [National Research Centre, Egypt]
	Lönnberg, Harri [University of Turku]
	Stephen, Andrew G. [Frederick National Laboratory for Cancer Research > NCI RAS Initiative]
	Papageorgiou, Anastassios C. [Turku Bioscience Centre, University of Turku and Åbo Akademi University]
	Virta, Pasi [University of Turku]
	Abankwa, Daniel [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit >]
Publication date :	2020
Journal title :	ACS Omega
Publisher :	American Chemical Society
Volume :	5
Issue/season :	1
Pages :	832-842
Peer reviewed :	Yes
Audience :	International
e-ISSN :	2470-1343
Country :	United States
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/10993/41426
DOI :	10.1021/acsomega.9b03639
Other URL :	https://pubs.acs.org/doi/abs/10.1021/acsomega.9b03639

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