Article (Scientific journals)
LIS1 and spindle orientation in neuroepithelial cells.
Schwamborn, Jens Christian; Knoblich, Juergen A.
2008In Cell Stem Cell, 2 (3), p. 193-4
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Keywords :
1-Alkyl-2-acetylglycerophosphocholine Esterase/metabolism; Animals; Brain/embryology; Cell Division/physiology; Mice; Microtubule-Associated Proteins/metabolism; Mitotic Spindle Apparatus/physiology; Neuroepithelial Cells/cytology/physiology; Stem Cells/cytology/physiology
Abstract :
[en] Asymmetric stem cell division is thought to require precise orientation of the mitotic spindle. However, a recent study in Cell (Yingling et al., 2008) analyzes the role of LIS1 in the developing mouse brain and shows that spindle orientation is more important during early, symmetric progenitor cell divisions than for later asymmetric divisions.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Schwamborn, Jens Christian ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit
Knoblich, Juergen A.
Language :
English
Title :
LIS1 and spindle orientation in neuroepithelial cells.
Publication date :
2008
Journal title :
Cell Stem Cell
ISSN :
1875-9777
Publisher :
Cell Press, United States - Massachusetts
Volume :
2
Issue :
3
Pages :
193-4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 21 June 2013

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