  | ARENA, G., LANDOULSI, Z., GROSSMANN, D., Payne, T., VITALI, A., DELCAMBRE, S., BARON, A., ANTONY, P., BOUSSAAD, I., BOBBILI, D. R., Sreelatha, A. A. K., PAVELKA, L., J Diederich, N., Klein, C., Seibler, P., GLAAB, E., Foltynie, T., Bandmann, O., Sharma, M., ... COURAGE‐PD Consortium. (2024). Polygenic Risk Scores Validated in Patient-Derived Cells Stratify for Mitochondrial Subtypes of Parkinson's Disease. Annals of Neurology. doi:10.1002/ana.26949  Peer Reviewed verified by ORBi |
 | KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19 Peer reviewed |
 | Gomez Ramos, B., Ohnmacht, J., de Lange, N., VALCESCHINI, E., GINOLHAC, A., CATILLON, M., FERRANTE, D., Rakovic, A., HALDER, R., Massart, F., ARENA, G., ANTONY, P., BOLOGNIN, S., Klein, C., KRAUSE, R., Schulz, M. H., SAUTER, T., Krüger, R., & SINKKONEN, L. (2023). Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. EMBO Reports. doi:10.1038/s44319-023-00024-2 Peer Reviewed verified by ORBi |
 | OLEKSY, C., Massart, F., Goldwurm, S., Arado, A., ARENA, G., BOUSSAAD, I., & Krüger, R. (October 2023). Generation and characterization of induced pluripotent stem cells from a Parkinson's disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations. Stem Cell Research, 72, 103212. doi:10.1016/j.scr.2023.103212 Peer Reviewed verified by ORBi |
 | Bitar, S., Baumann, T., Weber, C., Abusaada, M., Rojas-Charry, L., Ziegler, P., Schettgen, T., Randerath, I. E., Venkataramani, V., Michalke, B., ARENA, G., KRÜGER, R., Zhang, L., & Methner, A. (2023). Mitochondrial CISD1 is a downstream target that mediates PINK1 and Parkin loss-of-function phenotypes. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/60005. doi:10.1101/2023.09.28.559909 |
 | ARENA, G., LANDOULSI, Z., Grossmann, D., Vitali, A., DELCAMBRE, S., BARON, A., ANTONY, P., BOUSSAAD, I., BOBBILI, D. R., Sreelatha, A. A. K., PAVELKA, L., Klein, C., Seibler, P., GLAAB, E., Sharma, M., KRÜGER, R., MAY, P., & GRÜNEWALD, A. (2023). Polygenic risk scores validated in patient-derived cells stratify for mitochondrial subtypes of Parkinson\textquoterights disease 2023.05.12.23289877. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55367. doi:10.1101/2023.05.12.23289877 |
 | CHEMLA, A., ARENA, G., Onal, G., Walter, J., Berenguer-Escuder, C., Grossmann, D., GRÜNEWALD, A., SCHWAMBORN, J. C., & KRÜGER, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1. Stem Cell Research, 103145. doi:10.1016/j.scr.2023.103145 Peer reviewed |
 | CHEMLA, A., ARENA, G., SARAIVA, C., Berenguer-Escuder, C., Grossmann, D., GRÜNEWALD, A., Klein, C., Seibler, P., SCHWAMBORN, J. C., & KRÜGER, R. (2023). Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1. Stem Cell Research, 69, 103085. doi:10.1016/j.scr.2023.103085 Peer Reviewed verified by ORBi |
 | Nedara, K., Reinhardt, C., Lebraud, E., ARENA, G., Gracia, C., Buard, V., Pioche-Durieu, C., Castelli, F., Colsch, B., Bénit, P., Rustin, P., Albaud, B., Gestraud, P., Baulande, S., Servant, N., Deutsch, E., Verbavatz, J.-M., Brenner, C., Milliat, F., & Modjtahedi, N. (31 October 2022). Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation. Frontiers in Oncology, 12 (958155). doi:10.3389/fonc.2022.958155 Peer Reviewed verified by ORBi |
 | Di Rienzo, M., Romagnoli, A., Ciccosanti, F., Refolo, G., Consalvi, V., ARENA, G., Valente, E. M., Piacentini, M., & Fimia, G. M. (August 2022). AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability. Autophagy, 18 (8), 1752-1762. doi:10.1080/15548627.2021.1997052 Peer Reviewed verified by ORBi |
 | Brunelli, F., Torosantucci, L., Gelmetti, V., Franzone, D., GRÜNEWALD, A., KRÜGER, R., ARENA, G., & Valente, E. M. (2022). PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage. Cells, 11 (4). doi:10.3390/cells11040678 Peer Reviewed verified by ORBi |
 | Wasner, K., SMAJIC, S., GHELFI, J., DELCAMBRE, S., Prada-Medina, C. A., Knappe, E., ARENA, G., MULICA, P., AGYEAH, G., Rakovic, A., BOUSSAAD, I., BADANJAK, K., OHNMACHT, J., GERARDY, J.-J., Takanashi, M., Trinh, J., MITTELBRONN, M., Hattori, N., Klein, C., ... GRÜNEWALD, A. (2022). Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation. Movement disorders : official journal of the Movement Disorder Society. doi:10.1002/mds.29025 Peer reviewed |
 | ARENA, G., Sharma, K., AGYEAH, G., KRÜGER, R., GRÜNEWALD, A., & Fitzgerald, J. C. (2022). Neurodegeneration and Neuroinflammation in Parkinson’s Disease: a Self-Sustained Loop. Current Neurology and Neuroscience Reports, 22 (8), 427 – 440. doi:10.1007/s11910-022-01207-5 Peer reviewed |
  | Ragimbeau, R., El Kebriti, L., Sebti, S., Fourgous, E. F., Boulahtouf, A., ARENA, G., Espert, L., Turtoi, A., Gongora, C., Houédé, N., & Pattingre, S. (February 2021). BAG6 promotes PINK1 signaling pathway and is essential for mitophagy. FASEB Journal, 35 (2), 21361. doi:10.1096/fj.202000930R Peer Reviewed verified by ORBi |
 | JARAZO, J., BARMPA, K., Modamio, J., SARAIVA, C., SABATÉ SOLER, S., ROSETY, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., SMITS, L., Su, J., Arias-Fuenzalida, Walter, J., GOMEZ GIRO, G., Monzel, A., Qing, X., VITALI, A., CRUCIANI, G., BOUSSAAD, I., ... SCHWAMBORN, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 Peer Reviewed verified by ORBi |
 | ARENA, G., & KRÜGER, R. (2021). Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease: the PINK1/CHCHD4 interplay. Neural Regeneration Research. doi:10.4103/1673-5374.310679 Peer Reviewed verified by ORBi |
 | BRUNELLI, F., Valente, E. M., & ARENA, G. (2020). Mechanisms of neurodegeneration in Parkinson’s disease: keep neurons in the PINK1. Mechanisms of Ageing and Development. doi:10.1016/j.mad.2020.111277 Peer Reviewed verified by ORBi |
 | Berenguer-Escuder, C., Grossmann, D., ANTONY, P., ARENA, G., WASNER, K., MASSART, F., JARAZO, J., Walter, J., SCHWAMBORN, J. C., GRÜNEWALD, A., & KRÜGER, R. (2020). Impaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease. Human Molecular Genetics. doi:10.1093/hmg/ddaa066 Peer Reviewed verified by ORBi |
 | Bus, C., Zizmare, L., Feldkaemper, M., Geisler, S., Zarani, M., Schaedler, A., Klose, F., Admard, J., Mageean, C. J., ARENA, G., Fallier-Becker, P., Ugun-Klusek, A., Maruszczak, K. K., Kapolou, K., Schmid, B., Rapaport, D., Ueffing, M., Casadei, N., KRÜGER, R., ... Fitzgerald, J. C. (2020). Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors. iScience, 23 (12), 101797. doi:10.1016/j.isci.2020.101797 Peer Reviewed verified by ORBi |
 | Grossmann, D., Berenguer-Escuder, C., CHEMLA, A., ARENA, G., & KRÜGER, R. (2020). The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease. Frontiers in Neurology, 11, 587. doi:10.3389/fneur.2020.00587 Peer Reviewed verified by ORBi |
 | Lacroix, M., Riscal, R., ARENA, G., Linares, L. K., & Le Cam, L. (2020). Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer. Molecular Metabolism, 33, 2-22. doi:10.1016/j.molmet.2019.10.002 Peer Reviewed verified by ORBi |
 | Cissé, M. Y., Pyrdziak, S., Firmin, N., Gayte, L., Heuillet, M., Bellvert, F., Fuentes, M., Delpech, H., Riscal, R., ARENA, G., Chibon, F., Le Gellec, S., Maran-Gonzalez, A., Chateau, M.-C., Theillet, C., Carrere, S., Portais, J.-C., Le Cam, L., & Linares, L. K. (2020). Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma. Science Translational Medicine, 12 (547). doi:10.1126/scitranslmed.aay2163 Peer Reviewed verified by ORBi |
 | Reinhardt, C., ARENA, G., Nedara, K., Edwards, R., Brenner, C., Tokatlidis, K., & Modjtahedi, N. (2020). AIF meets the CHCHD4/Mia40-dependent mitochondrial import pathway. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (6), 165746. doi:10.1016/j.bbadis.2020.165746 Peer Reviewed verified by ORBi |
 | Al Amir Dache, Z., Otandault, A., Tanos, R., Pastor, B., Meddeb, R., Sanchez, C., ARENA, G., Lasorsa, L., Bennett, A., Grange, T., El Messaoudi, S., Mazard, T., Prevostel, C., & Thierry, A. R. (2020). Blood contains circulating cell-free respiratory competent mitochondria. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34 (3), 3616-3630. doi:10.1096/fj.201901917RR Peer reviewed |
 | ARENA, G., Riscal, R., Linares, L. K., & Le Cam, L. (2018). MDM2 controls gene expression independently of p53 in both normal and cancer cells. Cell Death and Differentiation, 25 (9), 1533-1535. doi:10.1038/s41418-018-0156-x Peer Reviewed verified by ORBi |
 | ARENA, G., Cissé, M. Y., Pyrdziak, S., Chatre, L., Riscal, R., Fuentes, M., Arnold, J. J., Kastner, M., Gayte, L., Bertrand-Gaday, C., Nay, K., Angebault-Prouteau, C., Murray, K., Chabi, B., Koechlin-Ramonatxo, C., Orsetti, B., Vincent, C., Casas, F., Marine, J.-C., ... Le Cam, L. (2018). Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53. Molecular Cell, 69 (4), 594-609.e8. doi:10.1016/j.molcel.2018.01.023 Peer Reviewed verified by ORBi |
 | Gelmetti, V., De Rosa, P., Torosantucci, L., Marini, E. S., Romagnoli, A., Di Rienzo, M., ARENA, G., Vignone, D., Fimia, G. M., & Valente, E. M. (2017). PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy, 13 (4), 654-669. doi:10.1080/15548627.2016.1277309 Peer Reviewed verified by ORBi |
 | ARENA, G., & Valente, E. M. (2017). PINK1 in the limelight: multiple functions of an eclectic protein in human health and disease. The Journal of pathology, 241 (2), 251-263. doi:10.1002/path.4815 Peer reviewed |
 | Chatre, L., Fernandes, J., Michel, V., Fiette, L., Avé, P., ARENA, G., Jain, U., Haas, R., Wang, T. C., Ricchetti, M., & Touati, E. (2017). Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms. Scientific Reports, 7 (1), 15901. doi:10.1038/s41598-017-15567-3 Peer Reviewed verified by ORBi |
 | Riscal, R., Schrepfer, E., ARENA, G., Cissé, M. Y., Bellvert, F., Heuillet, M., Rambow, F., Bonneil, E., Sabourdy, F., Vincent, C., Ait-Arsa, I., Levade, T., Thibaut, P., Marine, J.-C., Portais, J.-C., Sarry, J.-E., Le Cam, L., & Linares, L. K. (2016). Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53. Molecular Cell, 62 (6), 890-902. doi:10.1016/j.molcel.2016.04.033 Peer Reviewed verified by ORBi |
 | ARENA, G., Gelmetti, V., Torosantucci, L., Vignone, D., Lamorte, G., De Rosa, P., Cilia, E., Jonas, E. A., & Valente, E. M. (2013). PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage. Cell Death and Differentiation, 20 (7), 920-30. doi:10.1038/cdd.2013.19 Peer Reviewed verified by ORBi |
 | De Leo, A., ARENA, G., Lacanna, E., Oliviero, G., Colavita, F., & Mattia, E. (2012). Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt's lymphoma cells by affecting multiple molecular targets. Antiviral Research, 96 (2), 196-202. doi:10.1016/j.antiviral.2012.09.003 Peer Reviewed verified by ORBi |
 | Valente, E. M., ARENA, G., Torosantucci, L., & Gelmetti, V. (2012). Molecular pathways in sporadic PD. Parkinsonism & related disorders, 18 Suppl 1, 71-3. Peer reviewed |
 | De Leo, A., ARENA, G., Stecca, C., Raciti, M., & Mattia, E. (2011). Resveratrol inhibits proliferation and survival of Epstein Barr virus-infected Burkitt's lymphoma cells depending on viral latency program. Molecular cancer research : MCR, 9 (10), 1346-55. doi:10.1158/1541-7786.MCR-11-0145 Peer reviewed |
 | Michiorri, S., Gelmetti, V., Giarda, E., Lombardi, F., Romano, F., Marongiu, R., Nerini-Molteni, S., Sale, P., Vago, R., ARENA, G., Torosantucci, L., Cassina, L., Russo, M. A., Dallapiccola, B., Valente, E. M., & Casari, G. (2010). The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy. Cell Death and Differentiation, 17 (6), 962-74. doi:10.1038/cdd.2009.200 Peer Reviewed verified by ORBi |
 | De Leo, A., Matusali, G., ARENA, G., Di Renzo, L., & Mattia, E. (2010). Epstein-Barr virus lytic cycle activation alters proteasome subunit expression in Burkitt's lymphoma cells. Biological Chemistry, 391 (9), 1041-6. doi:10.1515/BC.2010.107 Peer Reviewed verified by ORBi |
 | Matusali, G., ARENA, G., De Leo, A., Di Renzo, L., & Mattia, E. (2009). Inhibition of p38 MAP kinase pathway induces apoptosis and prevents Epstein Barr virus reactivation in Raji cells exposed to lytic cycle inducing compounds. Molecular Cancer, 8, 18. doi:10.1186/1476-4598-8-18 Peer Reviewed verified by ORBi |
