Profil

BOUSSAAD Ibrahim

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Translational Neuroscience

Main Referenced Co-authors
KRÜGER, Rejko  (11)
SCHWAMBORN, Jens Christian  (7)
ANTONY, Paul  (6)
ARENA, Giuseppe  (6)
Klein, Christine (5)
Main Referenced Keywords
Parkinson's disease (3); Dopaminergic Neurons/metabolism (2); General Medicine (2); Humans (2); Parkinson Disease/metabolism (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (4)
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (4)
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (4)
LIH - Luxembourg Institute of Health (2)
Luxembourg Centre for Systems Biomedicine (LCSB): Developmental and Cellular Biology (Schwamborn Group) (2)
Main Referenced Disciplines
Neurology (6)
Biochemistry, biophysics & molecular biology (5)
Genetics & genetic processes (5)
Life sciences: Multidisciplinary, general & others (4)
Biotechnology (2)

Publications (total 17)

The most downloaded
449 downloads
Wasner, K., Smajic, S., Ghelfi, J., Delcambre, S., Prada-Medina, C. A., Knappe, E., Arena, G., Mulica, P., Agyeah, G., Rakovic, A., Boussaad, I., Badanjak, K., Ohnmacht, J., Gerardy, J.-J., Takanashi, M., Trinh, J., Mittelbronn, M., Hattori, N., Klein, C., ... Grünewald, A. (2022). Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation. Movement disorders : official journal of the Movement Disorder Society. doi:10.1002/mds.29025 https://hdl.handle.net/10993/51271

The most cited

278 citations (Scopus®)

Monzel, A. S., Smits, L., Hemmer, K., Hachi, S., Lucumi Moreno, E., Van Wüllen, T. M., Jarazo, J., Walter, J., Werthschulte, I., Boussaad, I., Berger, E., Fleming, R. M., Bolognin, S., & Schwamborn, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010 https://hdl.handle.net/10993/30751

ARENA, G., LANDOULSI, Z., GROSSMANN, D., Payne, T., VITALI, A., DELCAMBRE, S., BARON, A., ANTONY, P., BOUSSAAD, I., BOBBILI, D. R., Sreelatha, A. A. K., PAVELKA, L., J Diederich, N., Klein, C., Seibler, P., GLAAB, E., Foltynie, T., Bandmann, O., Sharma, M., ... COURAGE‐PD Consortium. (2024). Polygenic Risk Scores Validated in Patient-Derived Cells Stratify for Mitochondrial Subtypes of Parkinson's Disease. Annals of Neurology. doi:10.1002/ana.26949
Peer Reviewed verified by ORBi

KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19
Peer reviewed

OLEKSY, C., Massart, F., Goldwurm, S., Arado, A., ARENA, G., BOUSSAAD, I., & Krüger, R. (October 2023). Generation and characterization of induced pluripotent stem cells from a Parkinson's disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations. Stem Cell Research, 72, 103212. doi:10.1016/j.scr.2023.103212
Peer Reviewed verified by ORBi

Arena, G., Landoulsi, Z., Grossmann, D., Vitali, A., Delcambre, S., Baron, A., Antony, P., Boussaad, I., Bobbili, D. R., Sreelatha, A. A. K., Pavelka, L., Klein, C., Seibler, P., Glaab, E., Sharma, M., Krüger, R., May, P., & Grünewald, A. (2023). Polygenic risk scores validated in patient-derived cells stratify for mitochondrial subtypes of Parkinson\textquoterights disease 2023.05.12.23289877. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/55367. doi:10.1101/2023.05.12.23289877

Mahoney-Sanchez, L., Bouchaoui, H., Boussaad, I., Jonneaux, A., Timmerman, K., Berdeaux, O., Ayton, S., Krüger, R., Duce, J. A., Devos, D., & Devedjian, J.-C. (23 August 2022). Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition. Cell Reports, 40 (8), 111231. doi:10.1016/j.celrep.2022.111231
Peer Reviewed verified by ORBi

Wolf, C., Mencke, P., & Boussaad, I. (2022). GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton. Communications Biology. doi:10.1038/s42003-022-03487-6
Peer Reviewed verified by ORBi

Mencke, P., & Boussaad, I. (2022). Generation and characterization of a genetic Parkinson`s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A). Stem Cell Research. doi:10.1016/j.scr.2022.102792
Peer Reviewed verified by ORBi

Wasner, K., Smajic, S., Ghelfi, J., Delcambre, S., Prada-Medina, C. A., Knappe, E., Arena, G., Mulica, P., Agyeah, G., Rakovic, A., Boussaad, I., Badanjak, K., Ohnmacht, J., Gerardy, J.-J., Takanashi, M., Trinh, J., Mittelbronn, M., Hattori, N., Klein, C., ... Grünewald, A. (2022). Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation. Movement disorders : official journal of the Movement Disorder Society. doi:10.1002/mds.29025
Peer reviewed

Mencke, P., Boussaad, I., Romano, C., Kitami, T., Linster, C., & Krüger, R. (2021). The Role of DJ-1 in Cellular Metabolism and Pathophysiological Implications for Parkinson’s Disease. Cells. doi:10.3390/cells10020347
Peer Reviewed verified by ORBi

Brown, S. J., Boussaad, I., Jarazo, J., Fitzgerald, J. C., Antony, P., Keatinge, M., Blechman, J., Schwamborn, J. C., Krüger, R., Placzek, M., & Bandmann, O. (2021). PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons. Scientific Reports. doi:10.1038/s41598-021-84278-7
Peer Reviewed verified by ORBi

Boussaad, I., Cruciani, G., Bolognin, S., Antony, P., Dording, C., Kwon, Y.-J., Heuting, P., Fava, E., Schwamborn, J. C., & Krüger, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3
Peer Reviewed verified by ORBi

Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L., Su, J., Arias-Fuenzalida, Walter, J., Gomez Giro, G., Monzel, A., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., ... Schwamborn, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810
Peer Reviewed verified by ORBi

Wolf, C., Pouya, A., Bitar, S., Pfeiffer, A., Bueno, D., Arndt, S., Tenzer, S., Dal Bello, F., Vianello, C., Ritz, S., Schwirz, J., Dobrindt, K., Peitz, M., Hanschmann, E.-M., Boussaad, I., Brüstle, O., Giacomello, M., Krüger, R., & Methner, A. (2021). GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton 2021.03.04.433895. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/50307. doi:10.1101/2021.03.04.433895

Mencke, P., Hanss, Z., Boussaad, I., Sugier, P.-E., Elbaz, A., & Krüger, R. (2020). Bidirectional Relation Between Parkinson’s Disease and Glioblastoma Multiforme. Frontiers in Neurology. doi:10.3389/fneur.2020.00898
Peer reviewed

Boussaad, I., Obermaier, C. D., Hanss, Z., Bobbili, D. R., Bolognin, S., Glaab, E., Wołyńska, K., Weisschuh, N., De Conti, L., May, C., Giesert, F., Grossmann, D., Lambert, A., Kirchen, S., Biryukov, M., Burbulla, L. F., Massart, F., Bohler, J., Cruciani, G., ... Krüger, R. (2020). A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease. Science Translational Medicine, 12 (560). doi:10.1126/scitranslmed.aau3960
Peer Reviewed verified by ORBi

Hanss, Z., Boussaad, I., Jarazo, J., Schwamborn, J. C., & Krüger, R. (2019). Quality Control Strategy for CRISPRCas9- based Gene Editing Complicated by a Pseudogene. Frontiers in Genetics. doi:10.3389/fgene.2019.01297
Peer Reviewed verified by ORBi

Monzel, A. S., Smits, L., Hemmer, K., Hachi, S., Lucumi Moreno, E., Van Wüllen, T. M., Jarazo, J., Walter, J., Werthschulte, I., Boussaad, I., Berger, E., Fleming, R. M., Bolognin, S., & Schwamborn, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010
Peer Reviewed verified by ORBi

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