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GAIGNEAUX Anthoula

University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Health, Medicine and Life Sciences (DHML)

ORCID
0000-0003-0465-3773
Main Referenced Co-authors
LETELLIER, Elisabeth  (6)
HAAN, Serge  (5)
KONCINA, Eric  (5)
TSENKOVA, Mina  (5)
KARTA, Jessica  (4)
Main Referenced Keywords
Humans (6); Biochemistry, Genetics and Molecular Biology (all) (4); Cell Line, Tumor (3); Colorectal Neoplasms (3); Animals (2);
Main Referenced Unit & Research Centers
ULHPC - University of Luxembourg: High Performance Computing (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (17)
Gastroenterology & hepatology (2)
Microbiology (2)
Oncology (1)
Human health sciences: Multidisciplinary, general & others (1)

Publications (total 21)

The most downloaded
204 downloads
TERNES, D., KARTA, J., TSENKOVA, M., KONCINA, E., SCHMITZ, M., GRANDMOUGIN, L., GINOLHAC, A., GAIGNEAUX, A., RAMIRO GARCIA, J., WILMES, P., HAAN, S., & LETELLIER, E. (22 February 2020). Understanding the role of Fusobacterium nucleatum metabolism in colon cancer initiation and progression [Poster presentation]. The Microbiome, Viruses, and Cancer, Orlando, United States. https://hdl.handle.net/10993/46298

The most cited

264 citations (OpenAlex)

TERNES, D., TSENKOVA, M., POZDEEV, V., MEYERS, M., KONCINA, E., ATATRI, S., SCHMITZ, M., KARTA, J., SCHMOETTEN, M., Heinken, A., RODRIGUEZ, F., Delbrouck, C., GAIGNEAUX, A., GINOLHAC, A., Dan Nguyen, T. T., Grandmougin, L., Frachet-Bour, A., Martin-Gallausiaux, C., PIRES PACHECO, M. I., ... LETELLIER, E. (2022). The gut microbial metabolite formate exacerbates colorectal cancer progression. Nature Metabolism. doi:10.1038/s42255-022-00558-0 https://hdl.handle.net/10993/51992

KIRCHMEYER, M., GAIGNEAUX, A., SERVAIS, F., Arslanow, A., Rubie, C., Casper, M., Glanemann, M., Martínez-Chantar, M. L., Krawczyk, M., Lammert, F., & BEHRMANN, I. (2026). Identification of Circulating MiR-4651 as Novel Biomarker for Metabolic Dysfunction–Associated Steatotic Liver Disease. Gastro Hep Advances, 5 (2), 100839. doi:10.1016/j.gastha.2025.100839
Peer Reviewed verified by ORBi

KARTA, J.* , MEYERS, M.* , RODRIGUEZ, F., KONCINA, E., GILSON, C., KLEIN, E., GABOLA, M., BENZARTI, M., PEREZ ESCRIVA, P., MOLINA TIJERAS, J. A., CORREIA TAVARES BERNARDINO, C., Ponath, F., Carpentier, A., Pujabet, M. A., SCHMOETTEN, M., TSENKOVA, M., SAOUD, P., GAIGNEAUX, A., TERNES, D., ... LETELLIER, E. (October 2025). Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer. EMBO Journal, 44 (19), 5375 - 5393. doi:10.1038/s44318-025-00542-w
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

TSENKOVA, M., BRAUER, M., POZDEEV, V., KASAKIN, M., BUSI, S. B., SCHMOETTEN, M., CHEUNG, D., MEYERS, M., RODRIGUEZ, F., GAIGNEAUX, A., KONCINA, E., Gilson, C., SCHLICKER, L., Herebian, D., SCHMITZ, M., de Nies, L., Mayatepek, E., HAAN, S., de Beaufort, C., ... LETELLIER, E. (20 February 2025). Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate. Nature Communications, 16 (1), 1792. doi:10.1038/s41467-025-56678-0
Peer Reviewed verified by ORBi

STEFFEN, C.* , MANOHARAN, G. B.* , PAVIC, K., Yeste-Vázquez, A., Knuuttila, M., Arora, N., Zhou, Y., Härmä, H., GAIGNEAUX, A., Grossmann, T. N., & ABANKWA, D. (09 July 2024). Identification of an H-Ras nanocluster disrupting peptide. Communications Biology, 7 (1), 837. doi:10.1038/s42003-024-06523-9
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

GUREGHIAN, V., HERBST, H., KOZAR, I., MIHAJLOVIC, K., Malod-Dognin, N., Ceddia, G., ANGELI, C., WURTH-MARGUE, C., RANDIC, T., PHILIPPIDOU, D., TETSI NOMIGNI, M., HEMEDAN, A., TRANCHEVENT, L.-C., LONGWORTH, J., Bauer, M., BADKAS, A., GAIGNEAUX, A., Muller, A., OSTASZEWSKI, M., ... KREIS, S. (October 2023). A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma. Cancer Gene Therapy, 30 (10), 1330 - 1345. doi:10.1038/s41417-023-00640-z
Peer Reviewed verified by ORBi

MANOHARAN, G. B., STEFFEN, C., PAVIC, K., Yeste-Vázquez, A., Knuuttila, M., Arora, N., Zhou, Y., Härmä, H., GAIGNEAUX, A., Grossmann, T. N., & ABANKWA, D. (2023). Identification of an H-Ras nanocluster disrupting peptide. Cold Spring Harbor Laboratory. doi:10.1101/2023.09.07.556635

KAYA, P., SCHAFFNER-RECKINGER, E., MANOHARAN, G. B., Vukic, V., Kiriazis, A., LEDDA, M., Burgos, M., PAVIC, K., GAIGNEAUX, A., GLAAB, E., & ABANKWA, D. (2023). An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58308. doi:10.1101/2023.08.23.554263

KONCINA, E., NURMIK, M., POZDEEV, V., GILSON, C., TSENKOVA, M., BEGAJ, R., Stang, S., GAIGNEAUX, A., Weindorfer, C., RODRIGUEZ, F., SCHMOETTEN, M., KLEIN, E., KARTA, J., Atanasova, V. S., GRZYB, K., ULLMANN, P., HALDER, R., Hengstschläger, M., Graas, J., ... LETELLIER, E. (17 July 2023). IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer. Nature Communications, 14 (1), 4251. doi:10.1038/s41467-023-39953-w
Peer Reviewed verified by ORBi

ZHOU, Y., Nomigni, M. T., GAIGNEAUX, A., TOLLE, F., Wright, H. L., BUEB, J.-L., & BRECHARD, S. (2023). miRNA-132-5p mediates a negative feedback regulation of IL-8 secretion through S100A8/A9 downregulation in neutrophil-like HL-60 cells. Frontiers in Immunology, 14, 1274378. doi:10.3389/fimmu.2023.1274378
Peer Reviewed verified by ORBi

KIRCHMEYER, M.* , GAIGNEAUX, A.* , SERVAIS, F., Arslanow, A., Casper, M., Krawczyk, M., Lammert, F., & BEHRMANN, I. (2023). Altered profiles of circulating cytokines in chronic liver diseases (NAFLD/HCC): Impact of the PNPLA3I148M risk allele. Hepatology Communications. doi:10.1097/HC9.0000000000000306
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

TERNES, D., TSENKOVA, M., POZDEEV, V., MEYERS, M., KONCINA, E., ATATRI, S., SCHMITZ, M., KARTA, J., SCHMOETTEN, M., Heinken, A., RODRIGUEZ, F., Delbrouck, C., GAIGNEAUX, A., GINOLHAC, A., Dan Nguyen, T. T., Grandmougin, L., Frachet-Bour, A., Martin-Gallausiaux, C., PIRES PACHECO, M. I., ... LETELLIER, E. (2022). The gut microbial metabolite formate exacerbates colorectal cancer progression. Nature Metabolism. doi:10.1038/s42255-022-00558-0
Peer Reviewed verified by ORBi

THOMAS, M., Gui, Y., GARCIA, P., Karout, M., GOMEZ RAMOS, B., JÄGER, C., Michelucci, A., GAIGNEAUX, A., Kollmus, H., Centeno, A., Schughart, K., Balling, R., Mittelbronn, M., Nadeau, J. H., SAUTER, T., Williams, R. W., SINKKONEN, L., & BUTTINI, M. (2021). Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice. Genes, Brain, and Behavior. doi:10.1111/gbb.12769
Peer Reviewed verified by ORBi

Stadler, M., Pudelko, K., Biermeier, A., Walterskirchen, N., GAIGNEAUX, A., Weindorfer, C., Harrer, N., Klett, H., Hengstschläger, M., Schüler, J., Sommergruber, W., Oehler, R., Bergmann, M., LETELLIER, E., & Dolznig, H. (2021). Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages. Cancer Letters. doi:10.1016/j.canlet.2021.07.006
Peer Reviewed verified by ORBi

Chateauvieux, S., GAIGNEAUX, A., GERARD, D., Orsini, M., Morceau, F., Orlikova-Boyer, B., Farge, T., Récher, C., Sarry, J.-E., Dicato, M., & Diederich, M. (June 2020). Inflammation regulates long non-coding RNA-PTTG1-1:1 in myeloid leukemia [letter to the editor]. Haematologica, 105 (6), 280-E284.
Peer reviewed

Walbrecq, G., Lecha, O., GAIGNEAUX, A., Fougeras, M. R., PHILIPPIDOU, D., MARGUE, C., TETSI NOMIGNI, M., Bernardin, F., DITTMAR, G., BEHRMANN, I., & KREIS, S. (2020). Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles. Cancers. doi:10.3390/cancers12030692
Peer Reviewed verified by ORBi

TERNES, D., KARTA, J., TSENKOVA, M., KONCINA, E., SCHMITZ, M., GRANDMOUGIN, L., GINOLHAC, A., GAIGNEAUX, A., RAMIRO GARCIA, J., WILMES, P., HAAN, S., & LETELLIER, E. (22 February 2020). Understanding the role of Fusobacterium nucleatum metabolism in colon cancer initiation and progression [Poster presentation]. The Microbiome, Viruses, and Cancer, Orlando, United States.

Grandjenettea, C., Schnekenburger, M., GAIGNEAUX, A., GERARD, D., Christov, C., Mazumder, A., Dicato, M., & Diederich, M. (2020). Human telomerase reverse transcriptase depletion potentiates the growth- T inhibitory activity of imatinib in chronic myeloid leukemia stem cells. Cancer Letters. doi:10.1016/j.canlet.2019.11.017
Peer Reviewed verified by ORBi

Chateauvieux, S., GAIGNEAUX, A., Gérard, D., Orsini, M., Morceau, F., Orlikova-Boyer, B., Farge, T., Récher, C., Sarry, J.-E., Dicato, M., & Diederich, M. (2019). Inflammation Regulates Long Non-Coding RNA-PTTG1-1:1 In Myeloid Leukemia. Haematologica. doi:10.3324/haematol.2019.217
Peer Reviewed verified by ORBi

Orsini, M., Chateauvieux, S., Rhim, J., GAIGNEAUX, A., Cheillan, D., Christov, C., Dicato, M., Morceau, F., & Diederich, M. (September 2019). Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells. Cell Death and Differentiation, 26 (9), 1796–1812. doi:10.1038/s41418-018-0245-x
Peer Reviewed verified by ORBi

Mazumder, A., Lee, J., Talhi, O., Cerella, Chateauvieux, S., GAIGNEAUX, A., Hong, C., Kang, H., Lee, Y., Kim, K., Kim, D., Shin, H., Dicato, M., Bachari, K., Silva, A., Orlikova-Boyer, & Diederich, M. (2018). Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release. Cancer Letters. doi:10.1016/j.canlet.2018.07.041
Peer Reviewed verified by ORBi

Lee, J., Talhi, O., Jang, D., Cerella, C., GAIGNEAUX, A., Kim, K., Lee, J., Dicato, M., Bachari, K., Han, B., Silva, A., Orlikova, B., & Diederich, M. (2018). Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer. Cancer Letters. doi:10.1016/j.canlet.2017.12.007
Peer Reviewed verified by ORBi

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