  | KONCINA, E., NURMIK, M., POZDEEV, V., GILSON, C., TSENKOVA, M., BEGAJ, R., Stang, S., GAIGNEAUX, A., Weindorfer, C., RODRIGUEZ, F., SCHMOETTEN, M., KLEIN, E., KARTA, J., Atanasova, V. S., GRZYB, K., ULLMANN, P., HALDER, R., Hengstschläger, M., Graas, J., ... LETELLIER, E. (17 July 2023). IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer. Nature Communications, 14 (1), 4251. doi:10.1038/s41467-023-39953-w  Peer Reviewed verified by ORBi |
 | Bonetti, L., Horkova, V., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Grusdat, M., Spath, S., Koncina, E., Ewen, A., Binsfeld, C., Verschueren, C., Gérardy, J.-J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Chen, Y., ... BRENNER, D. (2023). A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58027. doi:10.1101/2023.07.06.547932 |
 | Lesur, A., Bernardin, F., KONCINA, E., LETELLIER, E., Kruppa, G., Schmit, P.-O., & DITTMAR, G. (02 June 2023). Quantification of 782 Plasma Peptides by Multiplexed Targeted Proteomics. Journal of Proteome Research, 22 (6), 1630 - 1638. doi:10.1021/acs.jproteome.2c00575 Peer Reviewed verified by ORBi |
 | Green, A. C., Marttila, P., Kiweler, N., Chalkiadaki, C., Wiita, E., Cookson, V., Lesur, A., Eiden, K., Bernardin, F., Vallin, K. S. A., Borhade, S., Long, M., Ghahe, E. K., Jiménez-Alonso, J. J., Jemth, A.-S., Loseva, O., Mortusewicz, O., MEYERS, M., VIRY, E., ... MEISER, J. (April 2023). Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells. Nature Metabolism, 5 (4), 642 - 659. doi:10.1038/s42255-023-00771-5 Peer Reviewed verified by ORBi |
 | Peiffer, R., Boumahd, Y., Gullo, C., Crake, R., Letellier, E., Bellahcène, A., & Peulen, O. (2023). Cancer-Associated Fibroblast Diversity Shapes Tumor Metabolism in Pancreatic CancerCancer-Associated Fibroblast Diversity Shapes Tumor Metabolism in Pancreatic Cancer. Cancers. doi:10.3390/cancers15010061 Peer Reviewed verified by ORBi |
 | Ternes, D., Tsenkova, M., Pozdeev, V., Meyers, M., Koncina, E., Atatri, S., Schmitz, M., Karta, J., Schmoetten, M., Heinken, A., Rodriguez, F., Delbrouck, C., Gaigneaux, A., Ginolhac, A., Dan Nguyen, T. T., Grandmougin, L., Frachet-Bour, A., Martin-Gallausiaux, C., Pires Pacheco, M. I., ... Letellier, E. (2022). The gut microbial metabolite formate exacerbates colorectal cancer progression. Nature Metabolism. doi:10.1038/s42255-022-00558-0 Peer reviewed |
 | Iglesias-González, A., Schweitzer, M., Palazzi, P., Peng, F., Haan, S., Letellier, E., & Appenzeller, B. (2022). Investigating children's chemical exposome - Description and possible determinants of exposure in the region of Luxembourg based on hair analysisInvestigating children's chemical exposome - Description and possible determinants of exposure in the region of Luxembourg based on hair analysis. Water and Environmental International. doi:10.1016/j.envint.2022.107342 Peer Reviewed verified by ORBi |
 | de Nies, L., Busi, S. B., Tsenkova, M., Halder, R., Letellier, E., & Wilmes, P. (2022). Evolution of the murine gut resistome following broad-spectrum antibiotic treatment. Nature Communications, 13 (1), 2296. doi:10.1038/s41467-022-29919-9 Peer Reviewed verified by ORBi |
 | Kiweler, N., Delbrouck, C., Pozdeev, V., Neises, L., Soriano-Bague, L., Eiden, K., Xian, F., Benzarti, M., Haase, L., Koncina, E., Schmoetten, M., JÄGER, C., Zaeem Noman, M., Vazquez, A., Janji, B., Dittmar, G., Brenner, D., Letellier, E., & Meiser, J. (2022). Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis. Nature Communications. doi:10.1038/s41467-022-30363-y Peer Reviewed verified by ORBi |
 | Stadler, M., Pudelko, K., Biermeier, A., Walterskirchen, N., Gaigneaux, A., Weindorfer, C., Harrer, N., Klett, H., Hengstschläger, M., Schüler, J., Sommergruber, W., Oehler, R., Bergmann, M., Letellier, E., & Dolznig, H. (2021). Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages. Cancer Letters. doi:10.1016/j.canlet.2021.07.006 Peer Reviewed verified by ORBi |
 | Karta, J., Bossicard, Y., Kotzamanis, K., Dolznig, H., & Letellier, E. (2021). Mapping the Metabolic Networks of Tumor Cells and Cancer-Associated Fibroblasts. Cells. doi:10.3390/cells10020304 Peer Reviewed verified by ORBi |
  | Lesur, A., Schmit, P.-O., Bernardin, F., Letellier, E., Brehmer, S., Decker, J., & Dittmar, G. (2021). Highly Multiplexed Targeted Proteomics Acquisition on a TIMS-QTOF. Analytical Chemistry. doi:10.1021/acs.analchem.0c03180 Peer Reviewed verified by ORBi |
 | Ternes, D., Karta, J., Tsenkova, M., Koncina, E., Schmitz, M., Grandmougin, L., Ginolhac, A., Gaigneaux, A., Ramiro Garcia, J., Wilmes, P., Haan, S., & Letellier, E. (22 February 2020). Understanding the role of Fusobacterium nucleatum metabolism in colon cancer initiation and progression [Poster presentation]. The Microbiome, Viruses, and Cancer, Orlando, United States. |
 | Ternes, D., Karta, J., Tsenkova, M., Wilmes, P., Haan, S., & Letellier, E. (2020). Microbiome in Colorectal Cancer: How to Getfrom Meta-omics to Mechanism? Trends in Microbiology. doi:10.1016/j.tim.2020.01.001 Peer Reviewed verified by ORBi |
 | Koncina, E., Haan, S., Rauh, S., & Letellier, E. (2020). Prognostic and Predictive Molecular Biomarkers for Colorectal Cancer: Updates and Challenges. Cancers. doi:10.3390/cancers12020319 Peer Reviewed verified by ORBi |
 | Letellier, E., & Koncina, E. (2020). Myosins: Driving us towards novel targets and biomarkers in cancer. In Actin Cytoskeleton in Cancer Progression and Metastasis - Part B (pp. 291-322). Elsevier. doi:10.1016/bs.ircmb.2020.06.004 Peer reviewed |
 | Qureshi-Baig, K., Kuhn, Viry, E., Pozdeev, V., Schmitz, M., Rodriguez, F., Ullmann, P., Koncina, E., Nurmik, M., Frasquilho, S., Nazarov, P. V., Zuegel, N., Boulmont, M., Karapetyan, Y., Antunes, L., Val, D., Mittelbronn, M., Janji, B., Haan, S., & Letellier, E. (2019). Hypoxia-induced Autophagy Drives Colorectal Cancer Initiation and Progression by Activating the PRKC/PKC-EZR (Ezrin) Pathway. Autophagy. doi:10.1080/15548627.2019.1687213 Peer Reviewed verified by ORBi |
 | Ullmann, P., Nurmik, M., Begaj, R., Haan, S., & Letellier, E. (01 June 2019). Hypoxia- and MicroRNA-Induced Metabolic Reprogramming of Tumor-Initiating Cells. Cells, 8 (6). doi:10.3390/cells8060528 Peer Reviewed verified by ORBi |
 | Pacheco, M., Bintener, T. J. R., Ternes, D., Kulms, D., Haan, S., Letellier, E., & Sauter, T. (May 2019). Identifying and targeting cancer-specific metabolism with network-based drug target prediction. EBioMedicine, 43 (May 2019), 98-106. doi:10.1016/j.ebiom.2019.04.046 Peer Reviewed verified by ORBi |
 | Ullmann, P., Nurmik, M., Schmitz, M., Rodriguez, F., Weilerr, J., Baig, K., Felten, P., Nazarov, P., NICOT, N., Zuegel, N., Haan, S., & Letellier, E. (May 2019). Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity. Cancer Letters, 450, 32-41. doi:10.1016/j.canlet.2019.02.030 Peer Reviewed verified by ORBi |
 | Greenhalgh, K., Ramiro Garcia, J., Heinken, Ullmann, P., Bintener, T. J. R., Pacheco, M., Baginska, J., Shah, P., Frachet Bour, A., Halder, R., Fritz, J., Sauter, T., Thiele, I., Haan, S., Letellier, E., & Wilmes, P. (30 April 2019). Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells. Cell Reports, 27, 1621–1632. doi:10.1016/j.celrep.2019.04.001 Peer Reviewed verified by ORBi |
 | Margue, C., Philippidou, D., Kozar, I., Cesi, G., Felten, P., Kulms, D., Letellier, E., Haan, C., & Kreis, S. (February 2019). Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells. Journal of Experimental and Clinical Cancer Research, 38 (1). doi:10.1186/s13046-019-1038-x Peer Reviewed verified by ORBi |
 | Nurmik, M., Ullmann, P., Rodriguez, F., Haan, S., & Letellier, E. (2019). In search of definitions: Cancer-associated fibroblasts and their markers. International Journal of Cancer. doi:10.1002/ijc.32193 Peer Reviewed verified by ORBi |
 | Dostert, C., Grustat, M., Letellier, E., & Brenner, D. (01 January 2019). The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond. Physiological Reviews, 99 (1). doi:10.1152/physrev.00045.2017 Peer Reviewed verified by ORBi |
 | Cesi, G., Philippidou, D., Kozar, I., Kim, Y. J., Bernardin, F., Van Niel, G., Wienecke-Baldacchino, A., Felten, P., Letellier, E., Dengler, S., Nashan, D., Haan, C., & Kreis, S. (2018). A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells. Molecular Cancer, (17:145). doi:10.1186/s12943-018-0886-x Peer Reviewed verified by ORBi |
 | Greenhalgh, K., Ramiro Garcia, J., Heinken, A. K., Baginska, J., Letellier, E., Halder, R., Frachet Bour, A., Ullmann, P., Thiele, I., Haan, S., & Wilmes, P. (16 February 2018). Cominatorial effect of dietary fibre and Lactobacillus rhamnosus in the context of colorectal cancer therapy [Poster presentation]. Cell Immunology symposium. |
 | Ullmann, P., Rodriguez, F., Schmitz, M., Meurer, S. K., Qureshi-Baig, K., Felten, P., Ginolhac, A., Antunes, L., Frasquilho, S., Zugel, N., Weiskirchen, R., Haan, S., & Letellier, E. (2018). The microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis. Cancer Research. doi:10.1158/0008-5472.CAN-17-3003 Peer Reviewed verified by ORBi |
LETELLIER, E., GINOLHAC, A., Schmitz Martine, & HAAN, S. (2018). NOVEL BIOMARKERS FOR CANCER DIAGNOSIS, PREDICTION OR STAGING. |
 | Letellier, E., Schmitz, M., Ginolhac, A., Rodriguez, F., Ullmann, P., Qureshi-Baig, K., Frasquilho, S., Antunes, L., & Haan, S. (21 November 2017). Loss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence. British Journal of Cancer, 117 (11), 1689-1701. doi:10.1038/bjc.2017.352 Peer Reviewed verified by ORBi |
 | Rolvering, C., Zimmer, A., Kozar, I., Hermanns, Letellier, E., Vallar, L., Nazarov, P., Nicot, N., Ginolhac, A., Haan, S., Behrmann, I., & Haan, C. (2017). Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines. BBA Molecular Cell Research, 516-526. doi:10.1016/J.BBAMCR.2016.12.006 Peer Reviewed verified by ORBi |
 | Baig, K., Ullmann, P., Haan, S., & Letellier, E. (2017). Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies. Molecular Cancer. doi:10.1186/s12943-017-0602-2 Peer Reviewed verified by ORBi |
 | Ternes, D., Wilmes, P., Letellier, E., & Haan, S. (05 February 2017). From meta-genomics to causality: Understanding the role of colon cancer-associated bacteria in colorectal cancer [Poster presentation]. Keystone symposia: Microbiome in Health and Disease (J8), Keystone, Colorado, United States. |
 | Bahlawane, C., Schmitz, M., Letellier, E., Arumugam, K., Nicot, N., Nazarov, P., & Haan, S. (2017). Insights into ligand stimulation effects on gastro-intestinal stromal tumors signalling. Cell Signal. doi:10.1016/j.cellsig.2016.10.009 Peer reviewed |
Greenhalgh, K., Fritz, J., Letellier, E., Ramiro Garcia, J., Halder, R., Frachet Bour, A., Baginska, J., Ternes, D., Jäger, C., Haan, S., & Wilmes, P. (2017). A study of the molecular mechanisms underlying teh response of human colorectal adenomacarcinoma enterocytes to prebiotics and probiotics [Poster presentation]. ISAPP conference. |
 | Bahlawane, C., Schmitz, M., Letellier, E., Arumugam, K., Nicot, N., Nazarov, P., & Haan, S. (2016). Data on quantification of signaling pathways activated by KIT and PDGFRA mutants. Data in Brief, (9), 828-838. doi:10.1016/j.dib.2016.10.026 Peer Reviewed verified by ORBi |
 | Ullmann, P., qureshi-baig, K., Rodriguez, F., Ginolhac, A., nonnenmacher, Y., Ternes, D., Weiler, J., Gaebler, K., bahlawane, C., hiller, K., Haan, S., & Letellier, E. (04 October 2016). Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production. Oncotarget, 7 (40), 97-114. doi:10.18632/oncotarget.11772 Peer Reviewed verified by ORBi |
 | Greenhalgh, K., Fritz, J., Letellier, E., Frachet Bour, A., Baginska, J., Shah, P., Desai, M., Glaab, E., Jäger, C., Haan, S., & Wilmes, P. (June 2016). A study of the molecular mechanisms underlying the response of human colorectal adenomacarcinoma enterocytes to prebiotics and probiotics [Poster presentation]. ISAPP conference. |
 | Letellier, E., & Haan, S. (2016). SOCS2: physiological and pathological functions. Frontiers in Bioscience (Elite Edition), 8, 189-204. doi:10.2741/760 Peer Reviewed verified by ORBi |
 | Baig, K., Ullmann, P., Rodriguez, F., Frasquilho, S., Nazarov, P. V., Haan, S., & Letellier, E. (January 2016). What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue. PLoS ONE, 11. doi:10.1371/JOURNAL.PONE.0146052 Peer Reviewed verified by ORBi |
 | Letellier, E., Schmitz, M., Baig, K., Beaume, N., Schwartz, C., Frasquilho, S., Antunes, L., Marcon, N., Nazarov, P. V., Vallar, L., Even, J., & Haan, S. (2014). Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer. British Journal of Cancer, 111 (4), 726-35. doi:10.1038/bjc.2014.377 Peer Reviewed verified by ORBi |
| Pitzer, C., Klussmann, S., Krüger, C., Letellier, E., Plaas, C., Dittgen, T., Kirsch, F., Stieltjes, B., Weber, D., Laage, R., Martin-Villalba, A., & Schneider, A. (May 2010). The hematopoietic factor granulocyte-colony stimulating factor improves outcome in experimental spinal cord injury. Journal of Neurochemistry, 113, 930-942. doi:10.1111/j.1471-4159.2010.06659.x Peer Reviewed verified by ORBi |
| Letellier, E., Kumar S, Sancho-Martinez I, Krauth S, Funke-Kaiser A, Laudenklos S, Konecki K, Klussmann S, Corsini NS, Kleber S, Drost N, Neumann A, Lévi-Strauss M, Brors B, Gretz N, Edler L, Fischer C, Hill O, Thiemann M, ... Martin-Villalba A. (February 2010). CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site. Immunity, 32. doi:10.1016/j.immuni.2010.01.011 Peer reviewed |
| Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Kumar S, Letellier, E., Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B,, Brüstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, ... Martin-Villalba A. (07 August 2009). The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair. Cell Stem Cell, 5. doi:10.1016/j.stem.2009.05.004 Peer reviewed |
| Kleber, S., Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, schreglmann n, Letellier, E., Zuliani C, Klussmann S, Teodorczyk M, Gröne HJ, Ganten TM, Sültmann H, Tüttenberg J, ... Martin-Villalba A., A. (March 2008). Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell, 13. doi:10.1016/j.ccr.2008.02.003 Peer reviewed |
Letellier, E., & Martin-Villalba, A. (June 2007). Spinal cord injuries entering the Fas(t) lane. Neurosurgery, 6. Peer Reviewed verified by ORBi |
| Stieltjes B,, Klussmann S, Bock M, Umathum R, Mangalathu J, Letellier, E., Rittgen W, Edler L, & martin-villalba, A. (May 2006). Manganese-enhanced magnetic resonance imaging for in vivo assessment of damage and functional improvement following spinal cord injury in mice. Magn Reson Med, 5. Peer reviewed |