  | KONCINA, E., NURMIK, M., POZDEEV, V., GILSON, C., TSENKOVA, M., BEGAJ, R., Stang, S., GAIGNEAUX, A., Weindorfer, C., RODRIGUEZ, F., SCHMOETTEN, M., KLEIN, E., KARTA, J., Atanasova, V. S., GRZYB, K., ULLMANN, P., HALDER, R., Hengstschläger, M., Graas, J., ... LETELLIER, E. (17 July 2023). IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer. Nature Communications, 14 (1), 4251. doi:10.1038/s41467-023-39953-w  Peer Reviewed verified by ORBi |
Dosquet, H., Neirinckx, V., MEYRATH, M. M. R., Wantz, M., HAAN, S., NICLOU, S. P., SZPAKOWSKA, M., & Chevigné, A. (2023). Nanoluciferase-based complementation assays to monitor activation, modulation and signaling of receptor tyrosine kinases (RTKs). In Chapter One - Nanoluciferase-based complementation assays to monitor activation, modulation and signaling of receptor tyrosine kinases (RTKs). Elsevier. doi:10.1016/bs.mie.2022.09.002 Peer Reviewed verified by ORBi |
 | Ternes, D., Tsenkova, M., Pozdeev, V., Meyers, M., Koncina, E., Atatri, S., Schmitz, M., Karta, J., Schmoetten, M., Heinken, A., Rodriguez, F., Delbrouck, C., Gaigneaux, A., Ginolhac, A., Dan Nguyen, T. T., Grandmougin, L., Frachet-Bour, A., Martin-Gallausiaux, C., Pires Pacheco, M. I., ... Letellier, E. (2022). The gut microbial metabolite formate exacerbates colorectal cancer progression. Nature Metabolism. doi:10.1038/s42255-022-00558-0 Peer reviewed |
 | Iglesias-González, A., Schweitzer, M., Palazzi, P., Peng, F., Haan, S., Letellier, E., & Appenzeller, B. (2022). Investigating children's chemical exposome - Description and possible determinants of exposure in the region of Luxembourg based on hair analysisInvestigating children's chemical exposome - Description and possible determinants of exposure in the region of Luxembourg based on hair analysis. Water and Environmental International. doi:10.1016/j.envint.2022.107342 Peer Reviewed verified by ORBi |
 | Fäys, F., Hardy, E. M., Palazzi, P., Haan, S., Beausoleil, C., & Appenzeller, B. (2021). Biomonitoring of fast-elimination endocrine disruptors - Results from a 6-month follow up on human volunteers with repeated urine and hair collection. The Science of the total environment, 778, 146330. doi:10.1016/j.scitotenv.2021.146330 Peer reviewed |
 | Ternes, D., Karta, J., Tsenkova, M., Koncina, E., Schmitz, M., Grandmougin, L., Ginolhac, A., Gaigneaux, A., Ramiro Garcia, J., Wilmes, P., Haan, S., & Letellier, E. (22 February 2020). Understanding the role of Fusobacterium nucleatum metabolism in colon cancer initiation and progression [Poster presentation]. The Microbiome, Viruses, and Cancer, Orlando, United States. |
  | Ternes, D., Karta, J., Tsenkova, M., Wilmes, P., Haan, S., & Letellier, E. (2020). Microbiome in Colorectal Cancer: How to Getfrom Meta-omics to Mechanism? Trends in Microbiology. doi:10.1016/j.tim.2020.01.001 Peer Reviewed verified by ORBi |
 | Koncina, E., Haan, S., Rauh, S., & Letellier, E. (2020). Prognostic and Predictive Molecular Biomarkers for Colorectal Cancer: Updates and Challenges. Cancers. doi:10.3390/cancers12020319 Peer Reviewed verified by ORBi |
 | Qureshi-Baig, K., Kuhn, Viry, E., Pozdeev, V., Schmitz, M., Rodriguez, F., Ullmann, P., Koncina, E., Nurmik, M., Frasquilho, S., Nazarov, P. V., Zuegel, N., Boulmont, M., Karapetyan, Y., Antunes, L., Val, D., Mittelbronn, M., Janji, B., Haan, S., & Letellier, E. (2019). Hypoxia-induced Autophagy Drives Colorectal Cancer Initiation and Progression by Activating the PRKC/PKC-EZR (Ezrin) Pathway. Autophagy. doi:10.1080/15548627.2019.1687213 Peer Reviewed verified by ORBi |
 | Ullmann, P., Nurmik, M., Begaj, R., Haan, S., & Letellier, E. (01 June 2019). Hypoxia- and MicroRNA-Induced Metabolic Reprogramming of Tumor-Initiating Cells. Cells, 8 (6). doi:10.3390/cells8060528 Peer Reviewed verified by ORBi |
 | Pacheco, M., Bintener, T. J. R., Ternes, D., Kulms, D., Haan, S., Letellier, E., & Sauter, T. (May 2019). Identifying and targeting cancer-specific metabolism with network-based drug target prediction. EBioMedicine, 43 (May 2019), 98-106. doi:10.1016/j.ebiom.2019.04.046 Peer Reviewed verified by ORBi |
 | Ullmann, P., Nurmik, M., Schmitz, M., Rodriguez, F., Weilerr, J., Baig, K., Felten, P., Nazarov, P., NICOT, N., Zuegel, N., Haan, S., & Letellier, E. (May 2019). Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity. Cancer Letters, 450, 32-41. doi:10.1016/j.canlet.2019.02.030 Peer Reviewed verified by ORBi |
 | Greenhalgh, K., Ramiro Garcia, J., Heinken, Ullmann, P., Bintener, T. J. R., Pacheco, M., Baginska, J., Shah, P., Frachet Bour, A., Halder, R., Fritz, J., Sauter, T., Thiele, I., Haan, S., Letellier, E., & Wilmes, P. (30 April 2019). Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells. Cell Reports, 27, 1621–1632. doi:10.1016/j.celrep.2019.04.001 Peer Reviewed verified by ORBi |
 | Nurmik, M., Ullmann, P., Rodriguez, F., Haan, S., & Letellier, E. (2019). In search of definitions: Cancer-associated fibroblasts and their markers. International Journal of Cancer. doi:10.1002/ijc.32193 Peer Reviewed verified by ORBi |
 | Greenhalgh, K., Ramiro Garcia, J., Heinken, A. K., Baginska, J., Letellier, E., Halder, R., Frachet Bour, A., Ullmann, P., Thiele, I., Haan, S., & Wilmes, P. (16 February 2018). Cominatorial effect of dietary fibre and Lactobacillus rhamnosus in the context of colorectal cancer therapy [Poster presentation]. Cell Immunology symposium. |
 | Rolvering, C., Zimmer, A. D., Ginolhac, A., Margue, C., Kirchmeyer, M., Servais, F., Hermanns, H. M., Hergovits, S., Nazarov, P. V., Nicot, N., Kreis, S., Haan, S., Behrmann, I., & Haan, C. (2018). The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by a-PD-L1 or a-IL6 antibodies. Journal of Leukocyte Biology, 104, 969-985. doi:10.1002/JLB.MA1217-495R Peer Reviewed verified by ORBi |
 | Ullmann, P., Rodriguez, F., Schmitz, M., Meurer, S. K., Qureshi-Baig, K., Felten, P., Ginolhac, A., Antunes, L., Frasquilho, S., Zugel, N., Weiskirchen, R., Haan, S., & Letellier, E. (2018). The microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis. Cancer Research. doi:10.1158/0008-5472.CAN-17-3003 Peer Reviewed verified by ORBi |
LETELLIER, E., GINOLHAC, A., Schmitz Martine, & HAAN, S. (2018). NOVEL BIOMARKERS FOR CANCER DIAGNOSIS, PREDICTION OR STAGING. |
 | Letellier, E., Schmitz, M., Ginolhac, A., Rodriguez, F., Ullmann, P., Qureshi-Baig, K., Frasquilho, S., Antunes, L., & Haan, S. (21 November 2017). Loss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence. British Journal of Cancer, 117 (11), 1689-1701. doi:10.1038/bjc.2017.352 Peer Reviewed verified by ORBi |
 | Rolvering, C., Zimmer, A., Kozar, I., Hermanns, Letellier, E., Vallar, L., Nazarov, P., Nicot, N., Ginolhac, A., Haan, S., Behrmann, I., & Haan, C. (2017). Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines. BBA Molecular Cell Research, 516-526. doi:10.1016/J.BBAMCR.2016.12.006 Peer Reviewed verified by ORBi |
 | Baig, K., Ullmann, P., Haan, S., & Letellier, E. (2017). Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies. Molecular Cancer. doi:10.1186/s12943-017-0602-2 Peer Reviewed verified by ORBi |
 | Ternes, D., Wilmes, P., Letellier, E., & Haan, S. (05 February 2017). From meta-genomics to causality: Understanding the role of colon cancer-associated bacteria in colorectal cancer [Poster presentation]. Keystone symposia: Microbiome in Health and Disease (J8), Keystone, Colorado, United States. |
 | Bahlawane, C., Schmitz, M., Letellier, E., Arumugam, K., Nicot, N., Nazarov, P., & Haan, S. (2017). Insights into ligand stimulation effects on gastro-intestinal stromal tumors signalling. Cell Signal. doi:10.1016/j.cellsig.2016.10.009 Peer reviewed |
Greenhalgh, K., Fritz, J., Letellier, E., Ramiro Garcia, J., Halder, R., Frachet Bour, A., Baginska, J., Ternes, D., Jäger, C., Haan, S., & Wilmes, P. (2017). A study of the molecular mechanisms underlying teh response of human colorectal adenomacarcinoma enterocytes to prebiotics and probiotics [Poster presentation]. ISAPP conference. |
 | Bahlawane, C., Schmitz, M., Letellier, E., Arumugam, K., Nicot, N., Nazarov, P., & Haan, S. (2016). Data on quantification of signaling pathways activated by KIT and PDGFRA mutants. Data in Brief, (9), 828-838. doi:10.1016/j.dib.2016.10.026 Peer Reviewed verified by ORBi |
 | Ullmann, P., qureshi-baig, K., Rodriguez, F., Ginolhac, A., nonnenmacher, Y., Ternes, D., Weiler, J., Gaebler, K., bahlawane, C., hiller, K., Haan, S., & Letellier, E. (04 October 2016). Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production. Oncotarget, 7 (40), 97-114. doi:10.18632/oncotarget.11772 Peer Reviewed verified by ORBi |
 | Martincuks, A., Fahrenkamp, D., Haan, S., Herrmann, A., Küster, A., & Müller-Newen, G. (August 2016). Dissecting functions of the N-terminal domain and GAS-site recognition in STAT3. Cellular Signalling, 28 (8), 810-25. doi:10.1016/j.cellsig.2016.03.011 Peer Reviewed verified by ORBi |
 | Greenhalgh, K., Fritz, J., Letellier, E., Frachet Bour, A., Baginska, J., Shah, P., Desai, M., Glaab, E., Jäger, C., Haan, S., & Wilmes, P. (June 2016). A study of the molecular mechanisms underlying the response of human colorectal adenomacarcinoma enterocytes to prebiotics and probiotics [Poster presentation]. ISAPP conference. |
 | Trairatphisan, P., Wiesinger, M., Bahlawane, C., Haan, S., & Sauter, T. (2016). A Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST. PLoS ONE, 11 (5), 0156223. doi:10.1371/journal.pone.0156223 Peer Reviewed verified by ORBi |
 | Letellier, E., & Haan, S. (2016). SOCS2: physiological and pathological functions. Frontiers in Bioscience (Elite Edition), 8, 189-204. doi:10.2741/760 Peer Reviewed verified by ORBi |
 | Baig, K., Ullmann, P., Rodriguez, F., Frasquilho, S., Nazarov, P. V., Haan, S., & Letellier, E. (January 2016). What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue. PLoS ONE, 11. doi:10.1371/JOURNAL.PONE.0146052 Peer Reviewed verified by ORBi |
 | Bahlawane, C., Eulenfeld, R., Wiesinger, M., Wang, J., Muller, A., Girod, A., Nazarov, P. V., Felsch, K., Vallar, L., Sauter, T., Satagopam, V., & Haan, S. (2015). Constitutive activation of oncogenic PDGFRalpha-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRalpha signalling characteristics. Cell Communication and Signaling, 13, 21. doi:10.1186/s12964-015-0096-8 Peer Reviewed verified by ORBi |
 | Haan, S., Bahlawane, C., Wang, J., Nazarov, P. V., Muller, A., Eulenfeld, R., Haan, C., Rolvering, C., Vallar, L., Satagopam, V., Sauter, T., & Wiesinger, M. (2015). The oncogenic FIP1L1-PDGFRalpha fusion protein displays skewed signaling properties compared to its wild-type PDGFRalpha counterpart. JAK-STAT, 4 (1), 1062596. doi:10.1080/21623996.2015.1062596 Peer reviewed |
 | Letellier, E., Schmitz, M., Baig, K., Beaume, N., Schwartz, C., Frasquilho, S., Antunes, L., Marcon, N., Nazarov, P. V., Vallar, L., Even, J., & Haan, S. (2014). Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer. British Journal of Cancer, 111 (4), 726-35. doi:10.1038/bjc.2014.377 Peer Reviewed verified by ORBi |
Heinrich, P. C., Haan, S., Hermanns, H. M., Müller-Newen, G., & Schaper, F. (2014). Kapitel 35: Rezeptoren und ihre Signaltransduktion. In P. C. Heinrich, M. Müller, ... L. Graeve (Eds.), Biochemie und Pathobiochemie (9th edition, pp. 411-441). Berlin, Germany: Springer. |
Heinrich, P. C., Haan, S., Hermanns, H. M., Müller-Newen, G., & Schaper, F. (2014). Kapitel 34: Mediatoren. In P. C. Heinrich, M. Müller, ... L. Graeve (Eds.), Biochemie und Pathobiochemie (9th edition, pp. 407-410). Berlin, Germany: Springer. |
 | Wolf, A., Eulenfeld, R., Gäbler, K., Rolvering, C., Haan, S., Behrmann, I., Denecke, B., Haan, C., & Schaper, F. (2013). JAK2-V617F-induced MAPK activity is regulated by PI3K and acts synergistically with PI3K on the proliferation of JAK2-V617F-positive cells. JAK-STAT, 2 (3), 24574. doi:10.4161/jkst.24574 Peer reviewed |
 | Haan, C., & Haan, S. (2013). Co-immunoprecipitation protocol to investigate cytokine receptor-associated proteins, e.g., Janus kinases or other associated signaling proteins. Methods in Molecular Biology, 967, 21-38. doi:10.1007/978-1-62703-242-1_2 Peer reviewed |
 | Haan, S., & Haan, C. (2013). Detection of activated STAT species using electrophoretic mobility shift assay (EMSA) and potential pitfalls arising from the use of detergents. Methods in Molecular Biology, 967, 147-59. doi:10.1007/978-1-62703-242-1_10 Peer reviewed |
Haan, C., Ungureanu, D., Pekkala, T., Silvennoinen, O., & Haan, S. (2012). Regulation of JAKs: Insights gleaned from the functional protein domains. In T. Decker & M. Müller (Eds.), JAK-STAT Signaling – From Basics to Disease (pp. 5-25). Wien, Austria: Springer-Verlag. doi:10.1007/978-3-7091-0891-8_2 |
 | Schoenherr, C., Weiskirchen, R., & Haan, S. (2010). Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses. Cell Communication and Signaling, 8, 19. doi:10.1186/1478-811X-8-19 Peer Reviewed verified by ORBi |
 | Haan, C., Behrmann, I., & Haan, S. (2010). Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases. Journal of Cellular and Molecular Medicine, 14 (3), 504-27. doi:10.1111/j.1582-4934.2010.01018.x Peer reviewed |
 | Haan, C., Kroy, D. C., Wüller, S., Sommer, U., Nöcker, T., Rolvering, C., Behrmann, I., Heinrich, P. C., & Haan, S. (2009). An unusual insertion in Jak2 is crucial for kinase activity and differentially affects cytokine responses. Journal of Immunology, 182 (5), 2969-2977. doi:10.4049/jimmunol.0800572 Peer Reviewed verified by ORBi |
 | Haan, S., Wuller, S., Kaczor, J., Rolvering, C., Nocker, T., Behrmann, I., & Haan, C. (2009). SOCS-mediated downregulation of mutant Jak2 (V617F, T875N and K539L) counteracts cytokine-independent signaling. Oncogene, 28 (34), 3069-80. doi:10.1038/onc.2009.155 Peer Reviewed verified by ORBi |
 | Wiesinger, M., Haan, S., Wuller, S., Kauffmann, M.-E., Recker, T., Kuster, A., Heinrich, P. C., & Muller-Newen, G. (2009). Development of an IL-6 inhibitor based on the functional analysis of murine IL-6Ralpha(1). Chemistry and Biology, 16 (7), 783-94. doi:10.1016/j.chembiol.2009.06.010 Peer reviewed |
 | Bender, H., Wiesinger, M., Nordhoff, C., Schoenherr, C., Haan, C., Ludwig, S., Weiskirchen, R., Kato, N., Heinrich, P. C., & Haan, S. (2009). Interleukin-27 displays interferon-gamma-like functions in human hepatoma cells and hepatocytes. Hepatology, 50 (2), 585-91. doi:10.1002/hep.22988 Peer Reviewed verified by ORBi |
Haan, S., Margue, C., Engrand, A., Rolvering, C., Schmitz-Van de Leur, H., Heinrich, P. C., Behrmann, I., & Haan, C. (2008). Dual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation. Journal of Immunology, 180 (2), 998-1007. doi:10.4049/jimmunol.180.2.998 Peer Reviewed verified by ORBi |
 | Kreis, S., Munz, G. A., Haan, S., Heinrich, P. C., & Behrmann, I. (2008). Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases. Molecular Cancer Research, 5 (12), 1331-41. doi:10.1158/1541-7786.MCR-07-0317 Peer Reviewed verified by ORBi |
Heinrich, P. C., Haan, S., Hermanns, H. M., Löffler, G., Müller-Newen, G., & Schaper, F. (2007). Kapitel 25: Kommunikation zwischen Zellen: Extrazelluläre Signalmoleküle, Rezeptoren und Signaltransduktion. In G. Löffler, P. E. Petrides, ... P. C. Heinrich (Eds.), Biochemie und Pathobiochemie (8th Edition, pp. 755-808). Berlin, Germany: Springer-Verlag. |
Isomoto, H., Mott, J. L., Kobayashi, S., Werneburg, N. W., Bronk, S. F., Haan, S., & Gores, G. J. (2007). Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. Gastroenterology, 132 (1), 384-96. doi:10.1053/j.gastro.2006.10.037 Peer Reviewed verified by ORBi |
Herrmann, A., Vogt, M., Monnigmann, M., Clahsen, T., Sommer, U., Haan, S., Poli, V., Heinrich, P. C., & Muller-Newen, G. (2007). Nucleocytoplasmic shuttling of persistently activated STAT3. Journal of Cell Science, 120 (Pt 18), 3249-61. doi:10.1242/jcs.03482 Peer Reviewed verified by ORBi |
Lehmann, U., Sommer, U., Smyczek, T., Hortner, M., Frisch, W., Volkmer-Engert, R., Heinrich, P. C., Schaper, F., & Haan, S. (2006). Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130. Cellular Signalling, 18 (1), 40-9. doi:10.1016/j.cellsig.2005.03.019 Peer Reviewed verified by ORBi |
Haan, S., Keller, J. F., Behrmann, I., Heinrich, P. C., & Haan, C. (2005). Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation. Cellular Signalling, 17 (12), 1542-50. doi:10.1016/j.cellsig.2005.03.010 Peer Reviewed verified by ORBi |
Sommer, U., Schmid, C., Sobota, R. M., Lehmann, U., Stevenson, N. J., Johnston, J. A., Schaper, F., Heinrich, P. C., & Haan, S. (2005). Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases. Journal of Biological Chemistry, 280 (36), 31478-88. doi:10.1074/jbc.M506008200 Peer Reviewed verified by ORBi |
Komyod, W., Bauer, U. M., Heinrich, P. C., Haan, S., & Behrmann, I. (2005). Are STATS arginine-methylated? Journal of Biological Chemistry, 280 (23), 21700-5. doi:10.1074/jbc.C400606200 Peer Reviewed verified by ORBi |
Radtke, S.* , Haan, S.* , Jörissen, A.* , Hermanns, H. M., Diefenbach, S., Smyczek, T., Schmitz-Vandeleur, H., Heinrich, P. C., Behrmann, I., & Haan, C. (2005). The Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/STAT signaling but plays a structural role for receptor interaction and up-regulation of receptor surface expression. Journal of Biological Chemistry, 280 (27), 25760-8. doi:10.1074/jbc.M500822200 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Hermanns, H. M., Muller-Newen, G., Heinrich, P. C., & Haan, S. (2005). Bow to your partner for signaling. Nature Structural and Molecular Biology, 12 (6), 476-8. doi:10.1038/nsmb0605-476 Peer Reviewed verified by ORBi |
Fischer, P., Lehmann, U., Sobota, R. M., Schmitz, J., Niemand, C., Linnemann, S., Haan, S., Behrmann, I., Yoshimura, A., Johnston, J. A., Müller-Newen, G., Heinrich, P. C., & Schaper, F. (2004). The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling. Biochemical Journal, 378 (Pt 2), 449-60. doi:10.1042/BJ20030893 Peer Reviewed verified by ORBi |
Herrmann, A., Sommer, U., Pranada, A. L., Giese, B., Kuster, A., Haan, S., Becker, W., Heinrich, P. C., & Muller-Newen, G. (2004). STAT3 is enriched in nuclear bodies. Journal of Cell Science, 117 (Pt 2), 339-49. doi:10.1242/jcs.00833 Peer Reviewed verified by ORBi |
Behrmann, I., Smyczek, T., Heinrich, P. C., Schmitz-Van de Leur, H., Komyod, W., Giese, B., Muller-Newen, G., Haan, S., & Haan, C. (2004). Janus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak.receptor complex to be equivalent to a receptor tyrosine kinase. Journal of Biological Chemistry, 279 (34), 35486-93. doi:10.1074/jbc.M404202200 Peer Reviewed verified by ORBi |
Stevenson, N. J.* , Haan, S.* , McClurg, A. E., McGrattan, M. J., Armstrong, M. A., Heinrich, P. C., & Johnston, J. A. (2004). The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine signaling-1 expression. Journal of immunology, 173 (5), 3243-9. doi:10.4049/jimmunol.173.5.3243 Peer reviewed* These authors have contributed equally to this work. |
Müller-Newen, G., Haan, S., & Heinrich, P. C. (2003). Fusionierte lösliche Rezeptoren als hochaktive Zytokin-Inhibitoren. Biospektrum, Sonderausgabe (9. Jahrgang), 480-483. |
Haan, S., Ferguson, P., Sommer, U., Hiremath, M., McVicar, D. W., Heinrich, P. C., Johnston, J. A., & Cacalano, N. A. (2003). Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation. Journal of Biological Chemistry, 278 (34), 31972-9. doi:10.1074/jbc.M303170200 Peer Reviewed verified by ORBi |
Heinrich, P. C.* , Behrmann, I.* , Haan, S.* , Hermanns, H. M.* , Müller-Newen, G.* , & Schaper, F.*. (2003). Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochemical Journal, 374 (Pt 1), 1-20. doi:10.1042/BJ20030407 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Ancey, C., Kuster, A., Haan, S., Herrmann, A., Heinrich, P. C., & Muller-Newen, G. (2003). A fusion protein of the gp130 and interleukin-6Ralpha ligand-binding domains acts as a potent interleukin-6 inhibitor. Journal of Biological Chemistry, 278 (19), 16968-72. doi:10.1074/jbc.C300081200 Peer Reviewed verified by ORBi |
Niemand, C., Nimmesgern, A., Haan, S., Fischer, P., Schaper, F., Rossaint, R., Heinrich, P. C., & Muller-Newen, G. (2003). Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. Journal of immunology, 170 (6), 3263-72. doi:10.4049/jimmunol.170.6.3263 Peer reviewed |
Hortner, M., Nielsch, U., Mayr, L. M., Heinrich, P. C., & Haan, S. (2002). A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor. European Journal of Biochemistry, 269 (10), 2516-26. doi:10.1046/j.1432-1033.2002.02916.x Peer Reviewed verified by ORBi |
Hortner, M., Nielsch, U., Mayr, L. M., Johnston, J. A., Heinrich, P. C., & Haan, S. (2002). Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. Journal of immunology, 169 (3), 1219-27. doi:10.4049/jimmunol.169.3.1219 Peer reviewed |
Schmitz, J., Weissenbach, M., Haan, S., Heinrich, P. C., & Schaper, F. (2000). SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. Journal of Biological Chemistry, 275 (17), 12848-56. doi:10.1074/jbc.275.17.12848 Peer Reviewed verified by ORBi |
Haan, S., Kortylewski, M., Behrmann, I., Müller-Esterl, W., Heinrich, P. C., & Schaper, F. (2000). Cytoplasmic STAT proteins associate prior to activation. Biochemical Journal, 345 Pt 3, 417-21. doi:10.1042/0264-6021:3450417 Peer Reviewed verified by ORBi |
Haan, S., Hemmann, U., Hassiepen, U., Schaper, F., Schneider-Mergener, J., Wollmer, A., Heinrich, P. C., & Grotzinger, J. (1999). Characterization and binding specificity of the monomeric STAT3-SH2 domain. Journal of Biological Chemistry, 274 (3), 1342-8. doi:10.1074/jbc.274.3.1342 Peer Reviewed verified by ORBi |