  | Mirizzi, G.* , Jelke, F.* , Pilot, M., Klein, K., Klamminger, G. G., GERARDY, J.-J., Theodoropoulou, M., MOMBAERTS, L., HUSCH, A., MITTELBRONN, M., HERTEL, F., & Kleine Borgmann, F. B. (06 March 2024). Impact of Formalin- and Cryofixation on Raman Spectra of Human Tissues and Strategies for Tumor Bank Inclusion. Molecules, 29 (5), 1167. doi:10.3390/molecules29051167  Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Merino Ruiz, C., PATRASKAKI, M., Gomez-Giro, G., Kleine Borgmann, F., Meyer, M., Carpentier, A., WARMOES, M. O., Jäger, C., MITTELBRONN, M., SCHWAMBORN, J. C., Cordero-Maldonado, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (March 2024). CLN3 deficiency leads to neurological and metabolic perturbations during early development. Life Science Alliance, 7 (3). doi:10.26508/lsa.202302057 Peer Reviewed verified by ORBi |
  | DEHGHANI, H., Holzapfel, G., MITTELBRONN, M., & ZILIAN, A. (27 February 2024). Cell adhesion affects the properties of interstitial fluid flow: A study using multiscale poroelastic composite modeling. Journal of the Mechanical Behavior of Biomedical Materials, 153. doi:10.1016/j.jmbbm.2024.106486 Peer Reviewed verified by ORBi |
 | Klein, K.* , Klamminger, G. G.* , MOMBAERTS, L., Jelke, F., Arroteia, I. F., Slimani, R., Mirizzi, G., HUSCH, A., FRAUENKNECHT, K., MITTELBRONN, M., HERTEL, F., & Kleine Borgmann, F. B. (23 February 2024). Computational Assessment of Spectral Heterogeneity within Fresh Glioblastoma Tissue Using Raman Spectroscopy and Machine Learning Algorithms. Molecules, 29 (5), 979. doi:10.3390/molecules29050979 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19 Peer reviewed |
Yabo, Y. A., Moreno-Sanchez, P. M., Pires-Afonso, Y., Kaoma, T., Nosirov, B., Scafidi, A., Ermini, L., Lipsa, A., Oudin, A., KYRIAKIS, D., GRZYB, K., POOVATHINGAL, S. K., Poli, A., Muller, A., TOTH, R., KLINK, B., BERCHEM, G. J. M. J., Berthold, C., HERTEL, F., ... GOLEBIEWSKA, A. (2023). Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/60199. doi:10.1101/2023.03.05.531162 |
 | SCHMIT, K.* , GARCIA, P.* , SCIORTINO, A., AHO, V., Pardo Rodriguez, B., THOMAS, M., GERARDY, J.-J., Bastero Acha, I., HALDER, R., CIALINI, C., HEURTAUX, T., Ostahi, I., BUSI, S. B., Grandmougin, L., LOWNDES, T., Singh, Y., Martens, E. C., MITTELBRONN, M., BUTTINI, M.* , & WILMES, P. (26 September 2023). Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease. Cell Reports, 42 (9), 113071. doi:10.1016/j.celrep.2023.113071 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | RANDIC, T., MAGNI, S., PHILIPPIDOU, D., Margue, C., GRZYB, K., PREIS, J. R., WROBLEWSKA, J. P., NAZAROV, P., MITTELBRONN, M., FRAUENKNECHT, K., SKUPIN, A., & KREIS, S. (25 July 2023). Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response. Cell Reports, 42 (7), 112696. doi:10.1016/j.celrep.2023.112696 Peer Reviewed verified by ORBi |
ALI, M.* , GARCIA, P.* , Laetitia P. Lunkes, SCIORTINO, A., THOMAS, M., HEURTAUX, T., GRZYB, K., HALDER, R., SKUPIN, A., MITTELBRONN, M., BUTTINI, M., & GLAAB, E. (12 May 2023). Gene Regulatory Network Analysis of Single-Cell Transcriptomes from THY-Tau22 Mice Reveals Sex-Dependent Immune Dysregulation associated with Alzheimer-like pathology [Poster presentation]. The 7th Venusberg Meeting on Neuroinflammation, Belval, Luxembourg. * These authors have contributed equally to this work. |
 | HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Ruiz, C. M., PATRASKAKI, M., Gomez-Giro, G., Borgmann, F. K., Meyer, M., Carpentier, A., WARMOES, M. O., JÄGER, C., MITTELBRONN, M., SCHWAMBORN, J. C., CORDERO MALDONADO, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (2023). CLN3 deficiency leads to neurological and metabolic perturbations during early development. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57737. doi:10.1101/2023.03.17.533107 |
 | Soriano-Baguet, L., Grusdat, M., Kurniawan, H., Benzarti, M., Binsfeld, C., Ewen, A., LONGWORTH, J., Bonetti, L., Guerra, L., Franchina, D. G., Kobayashi, T., Horkova, V., Verschueren, C., Helgueta, S., GERARD, D., More, T. H., Henne, A., Dostert, C., Farinelle, S., ... Brenner, D. (2023). Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions. Cell Reports. doi:10.1016/j.celrep.2023.112153 Peer Reviewed verified by ORBi |
 | Gargiulo, E., Viry, E., Morande, P. E., Largeot, A., Gonder, S., Xian, F., Ioannou, N., BENZARTI, M., Borgmann, F. B. K., MITTELBRONN, M., DITTMAR, G., NAZAROV, P., MEISER, J., Stamatopoulos, B., Ramsay, A. G., MOUSSAY, E.* , & PAGGETTI, J.*. (2023). Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses. Blood Cancer Discovery, 4 (1), 54 - 77. doi:10.1158/2643-3230.BCD-22-0029 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | ILINA, E., CIALINI, C., GERLOFF, D., Duarte Garcia-Escudero, M., Jeanty, C., Thézénas, M.-L., Lesur, A., Puard, V., Bernardin, F., Moter, A., Schuster, A., Dieterle, M., GOLEBIEWSKA, A., GERARDY, J.-J., DITTMAR, G., NICLOU, S. P., Müller, T., & MITTELBRONN, M. (18 February 2022). Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration. iScience, 25 (2), 103842. doi:10.1016/j.isci.2022.103842 Peer Reviewed verified by ORBi |
 | GARCIA, P., Wemheuer, W., Uriarte, O., MICHELUCCI, A., Masuch, A., Brioschi, S., Weihofen, A., KONCINA, E., COOWAR, D., HEURTAUX, T., GLAAB, E., BALLING, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., ... BUTTINI, M. (2022). Neurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease. Glia. doi:10.1002/glia.24149 Peer Reviewed verified by ORBi |
 | FIXEMER, S., AMELI, C., Hammer, G., Salamanca, L., Uriarte Huarte, O., Schwartz, C., GERARDY, J.-J., Mechawar, N., SKUPIN, A., MITTELBRONN, M., & BOUVIER, D. (2022). Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies. Acta Neuropathologica Communications, 10 (1), 36. doi:10.1186/s40478-022-01342-7 Peer Reviewed verified by ORBi |
 | Wasner, K., SMAJIC, S., GHELFI, J., DELCAMBRE, S., Prada-Medina, C. A., Knappe, E., ARENA, G., MULICA, P., AGYEAH, G., Rakovic, A., BOUSSAAD, I., BADANJAK, K., OHNMACHT, J., GERARDY, J.-J., Takanashi, M., Trinh, J., MITTELBRONN, M., Hattori, N., Klein, C., ... GRÜNEWALD, A. (2022). Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation. Movement disorders : official journal of the Movement Disorder Society. doi:10.1002/mds.29025 Peer reviewed |
 | HEURTAUX, T., KIRCHMEYER, M., KONCINA, E., Richart, L., Uriarte Huarte, O., Schohn, H., & MITTELBRONN, M. (2021). Apomorphine Reduces A53T α‑Synuclein‑Induced Microglial Reactivity Through Activation of NRF2 Signalling Pathway. Cellular and Molecular Neurobiology. doi:10.1007/s10571-021-01131-1 Peer Reviewed verified by ORBi |
 | URIARTE HUARTE, O., KYRIAKIS, D., HEURTAUX, T., Pires-Afonso, Y., GRZYB, K., HALDER, R., BUTTINI, M., SKUPIN, A., MITTELBRONN, M., & Michelucci, A. (2021). Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway. Frontiers in Immunology. doi:10.3389/fimmu.2021.639613 Peer Reviewed verified by ORBi |
 | Klamminger, G. G., GERARDY, J.-J., Jelke, F., Mirizzi, G., Slimani, R., Klein, K., HUSCH, A., HERTEL, F., MITTELBRONN, M., & Kleine-Borgmann, F. B. (2021). Application of Raman Spectroscopy for Detection of Histologically Distinct Areas in Formalin-fixed Paraffin-embedded (FFPE) Glioblastoma. Neuro-Oncology Advances. doi:10.1093/noajnl/vdab077 Peer Reviewed verified by ORBi |
 | Klamminger, G. G., Klein, K., MOMBAERTS, L., Jelke, F., Mirizzi, G., Slimani, R., HUSCH, A., MITTELBRONN, M., HERTEL, F., & Borgmann, F. B. K. (2021). Differentiation of primary CNS lymphoma and glioblastoma using Raman spectroscopy and machine learning algorithms. Free Neuropathology, 2, 26-26. doi:10.17879/freeneuropathology-2021-3458 Peer Reviewed verified by ORBi |
 | Jelke, F., Mirizzi, G., Borgmann, F. K., HUSCH, A., Slimani, R., Klamminger, G. G., Klein, K., MOMBAERTS, L., GERARDY, J.-J., MITTELBRONN, M., & HERTEL, F. (2021). Intraoperative discrimination of native meningioma and dura mater by Raman spectroscopy. Scientific Reports, 1--10. doi:10.1038/s41598-021-02977-7 Peer Reviewed verified by ORBi |
 | GOLEBIEWSKA, A., Hau, A.-C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., MICHELUCCI, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., AZUAJE, F., De Falco, A., Flies, B., ... NICLOU, S. (2020). Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology. Acta Neuropathologica. doi:10.1007/s00401-020-02226-7 Peer Reviewed verified by ORBi |
 | GUI, Y., Thomas, M. H., Garcia, P., Karout, M., HALDER, R., MICHELUCCI, A., Kollmus, H., Zhou, C., Melmed, S., Schughart, K., BALLING, R., MITTELBRONN, M., Nadeau, J. H., Williams, R. W., SAUTER, T., BUTTINI, M., & SINKKONEN, L. (2020). Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging. Frontiers in Genetics. doi:10.3389/fgene.2020.566734 Peer Reviewed verified by ORBi |
 | GOLEBIEWSKA, A., Hau, A.-C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., MICHELUCCI, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., AZUAJE, F., De Falco, A., Flies, B., ... NICLOU, S. (2020). Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/43022. doi:10.1101/2020.04.24.057802 |
 | Qureshi-Baig, K., Kuhn, Viry, E., POZDEEV, V., SCHMITZ, M., RODRIGUEZ, F., Ullmann, P., KONCINA, E., NURMIK, M., Frasquilho, S., Nazarov, P. V., Zuegel, N., Boulmont, M., Karapetyan, Y., Antunes, L., Val, D., MITTELBRONN, M., Janji, B., HAAN, S., & LETELLIER, E. (2019). Hypoxia-induced Autophagy Drives Colorectal Cancer Initiation and Progression by Activating the PRKC/PKC-EZR (Ezrin) Pathway. Autophagy. doi:10.1080/15548627.2019.1687213 Peer Reviewed verified by ORBi |
 | Zeiner, P. S., Preusse, C., GOLEBIEWSKA, A., Zinke, J., Iriondo, A., Muller, A., Kaoma, T., Filipski, K., Müller-Eschner, M., Bernatz, S., Blank, A.-E., Baumgarten, P., ILINA, E., Grote, A., Hansmann, M. L., Verhoff, M. A., Franz, K., Feuerhake, F., Steinbach, J. P., ... MITTELBRONN, M. (July 2019). Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas. Brain Pathology, 29 (4), 513-529. doi:10.1111/bpa.12690 Peer Reviewed verified by ORBi |
Kleine Borgmann, F., HUSCH, A., Slimani, R., Jelke, F., Mirizzi, G., Klein, K., MITTELBRONN, M., & HERTEL, F. (2019). PATH-29. POTENTIAL OF RAMAN SPECTROSCOPY IN ONCOLOGICAL NEUROSURGERY [Poster presentation]. 24th Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology, Phoenix, Arizona, United States. doi:10.1093/neuonc/noz175.625 |
 | Dudvarski Stanković, N., Bicker, F., Keller, S., Jones, D. T., Harter, P. N., Kienzle, A., Gillmann, C., Arnold, P., GOLEBIEWSKA, A., Keunen, O., Giese, A., von Deimling, A., Bäuerle, T., NICLOU, S. P., MITTELBRONN, M., Ye, W., Pfister, S. M., & Schmidt, M. H. (September 2018). EGFL7 enhances surface expression of integrin α(5)β(1) to promote angiogenesis in malignant brain tumors. EMBO Molecular Medicine, 10 (9). doi:10.15252/emmm.201708420 Peer Reviewed verified by ORBi |
 | Mäder, L., Blank, A. E., Capper, D., Jansong, J., Baumgarten, P., Wirsik, N. M., Zachskorn, C., Ehlers, J., Seifert, M., KLINK, B., Liebner, S., NICLOU, S. P., Naumann, U., Harter, P. N., & MITTELBRONN, M. (08 May 2018). Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma. Oncotarget, 9 (35), 24041-24053. doi:10.18632/oncotarget.25275 Peer Reviewed verified by ORBi |
 | Armento, A., ILINA, E., Kaoma, T., Muller, A., Vallar, L., NICLOU, S. P., Krüger, M. A., MITTELBRONN, M., & Naumann, U. (August 2017). Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors. International Journal of Oncology, 51 (2), 702-714. doi:10.3892/ijo.2017.4051 Peer Reviewed verified by ORBi |
 | Talasila, K. M., Røsland, G. V., Hagland, H. R., Eskilsson, E., Flønes, I. H., FRITAH, S., AZUAJE, F., Atai, N., Harter, P. N., MITTELBRONN, M., Andersen, M., Joseph, J. V., Hossain, J. A., Vallar, L., Noorden, C. J. F. V., NICLOU, S. P., Thorsen, F., Tronstad, K. J., Tzoulis, C., ... Miletic, H. (01 March 2017). The angiogenic switch leads to a metabolic shift in human glioblastoma. Neuro-Oncology, 19 (3), 383-393. doi:10.1093/neuonc/now175 Peer Reviewed verified by ORBi |
 | Bougnaud, S., GOLEBIEWSKA, A., Oudin, A., Keunen, O., Harter, P. N., Mäder, L., AZUAJE, F., FRITAH, S., Stieber, D., Kaoma, T., Vallar, L., Brons, N. H. C., Daubon, T., Miletic, H., Sundstrøm, T., Herold-Mende, C., MITTELBRONN, M., Bjerkvig, R., & NICLOU, S. P. (31 May 2016). Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma. Oncotarget, 7 (22), 31955 - 31971. doi:10.18632/oncotarget.7454 Peer Reviewed verified by ORBi |
 | Fack, F., Espedal, H., Keunen, O., GOLEBIEWSKA, A., Obad, N., Harter, P. N., MITTELBRONN, M., Bähr, O., Weyerbrock, A., Stuhr, L., Miletic, H., Sakariassen, P. Ø., Stieber, D., Rygh, C. B., Lund-Johansen, M., Zheng, L., Gottlieb, E., NICLOU, S. P., & Bjerkvig, R. (January 2015). Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas. Acta Neuropathologica, 129 (1), 115-31. doi:10.1007/s00401-014-1352-5 Peer Reviewed verified by ORBi |