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NICKELS Sarah Louise

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Developmental and Cellular Biology

Main Referenced Co-authors
SCHWAMBORN, Jens Christian  (15)
BOLOGNIN, Silvia  (6)
ANTONY, Paul  (5)
JARAZO, Javier  (5)
GLAAB, Enrico  (4)
Main Referenced Keywords
Biochemistry, Genetics and Molecular Biology (all) (2); General Medicine (2); Humans (2); Parkinson's disease (2); 3D cultures (1);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Developmental and Cellular Biology (Schwamborn Group) (2)
Integrative Research Unit: Social and Individual Development (INSIDE) > PEARL Institute for Research on Socio-Economic Inequality (IRSEI) (1)
LIH - Luxembourg Institute of Health (1)
Luxembourg Centre for Systems Biomedicine (LCSB) (1)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (6)
Biotechnology (4)
Neurology (3)
Genetics & genetic processes (2)
Microbiology (1)

Publications (total 16)

The most downloaded
330 downloads
SABATÉ SOLER, S., NICKELS, S. L., SARAIVA, C., Berger, E., Dubonyte, U., BARMPA, K., Lan, Y. J., Kouno, T., JARAZO, J., ROBERTSON, G., Sharif, J., Koseki, H., Thome, C., Shin, J., Cowley, S., & SCHWAMBORN, J. C. (2022). Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality. Glia. doi:10.1002/glia.24167 https://hdl.handle.net/10993/50796

The most cited

112 citations (OpenAlex)

BOLOGNIN, S., Fossépré, M., Qing, X., JARAZO, J., Ščančar, J., LUCUMI MORENO, E., NICKELS, S., WASNER, K., OUZREN, N., WALTER, J., GRÜNEWALD, A., GLAAB, E., Salamanca, L., Fleming, R. M. T., ANTONY, P., & SCHWAMBORN, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927 https://hdl.handle.net/10993/37469

KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19
Peer reviewed

ZAGARE, A., Preciat, G., NICKELS, S. L., Luo, X., MONZEL, A. S., Gomez-Giro, G., ROBERTSON, G., Jaeger, C., Sharif, J., Koseki, H., DIEDERICH, N., GLAAB, E., FLEMING, R. M., & SCHWAMBORN, J. C. (20 November 2023). Omics data integration suggests a potential idiopathic Parkinson's disease signature. Communications Biology, 6 (1), 1179. doi:10.1038/s42003-023-05548-w
Peer Reviewed verified by ORBi

Mendes-Pinheiro, B., Campos, J., Marote, A., Soares-Cunha, C., NICKELS, S. L., MONZEL, A. S., Cibrão, J. R., Loureiro-Campos, E., Serra, S. C., Barata-Antunes, S., Duarte-Silva, S., Pinto, L., SCHWAMBORN, J. C., & Salgado, A. J. (02 November 2023). Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration. Cells, 12 (21), 2565. doi:10.3390/cells12212565
Peer Reviewed verified by ORBi

SABATÉ SOLER, S., NICKELS, S. L., SARAIVA, C., Berger, E., Dubonyte, U., BARMPA, K., Lan, Y. J., Kouno, T., JARAZO, J., ROBERTSON, G., Sharif, J., Koseki, H., Thome, C., Shin, J., Cowley, S., & SCHWAMBORN, J. C. (2022). Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality. Glia. doi:10.1002/glia.24167
Peer Reviewed verified by ORBi

ZAGARE, A., BARMPA, K., SMAJIC, S., SMITS, L., GRZYB, K., GRÜNEWALD, A., SKUPIN, A., NICKELS, S. L., & SCHWAMBORN, J. C. (2022). Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression. American Journal of Human Genetics. doi:10.1016/j.ajhg.2021.12.009
Peer Reviewed verified by ORBi

BOLOGNIN, S., SMITS, L., NICKELS, S. L., MAGNI, S., ANTONY, P., GRZYB, K., KRÜGER, R., SKUPIN, A., & SCHWAMBORN, J. C. (2021). A new brain organoid model to study Parkinson’s Disease. Biomedical Science and Engineering.

NICKELS, S. L., & SCHWAMBORN, J. C. (2021). Is serine racemase (SRR) a second hit target for LRRK2-G2019S induced Parkinson’s disease? Neural Regeneration Research. doi:10.4103/1673-5374.293140
Peer Reviewed verified by ORBi

Walter, J., BOLOGNIN, S., Poovathingal, S., MAGNI, S., GERARD, D., ANTONY, P., NICKELS, S. L., Salamanca, L., Berger, E., SMITS, L., GRZYB, K., Perfeito, R., Hoel, F., Qing, X., OHNMACHT, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... SCHWAMBORN, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864
Peer Reviewed verified by ORBi

NICKELS, S. L., MODAMIO CHAMARRO, J., Mendes-Pinheiro, B., MONZEL, A. S., BETSOU, F., & SCHWAMBORN, J. C. (2020). Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease. Stem Cell Research. doi:10.1016/j.scr.2020.101870
Peer Reviewed verified by ORBi

Walter, J., BOLOGNIN, S., ANTONY, P., NICKELS, S., Poovathhingal, S., Salamanca, L., MAGNI, S., Perfeito, R., Hoel, F., Qing, X., JARAZO, J., Arias-Fuenzalida, J., Ignac, T., MONZEL, A. S., Gonzalez-Cano, L., Pereira de Almeida, L., SKUPIN, A., Tronstad, K., & SCHWAMBORN, J. C. (2019). Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality. Stem Cell Reports. doi:10.1016/j.stemcr.2019.03.004
Peer Reviewed verified by ORBi

NICKELS, S., Walter, J., BOLOGNIN, S., GERARD, D., Jäger, C., Qing, X., Tisserand, J., JARAZO, J., Hemmer, K., Harms, A., HALDER, R., Lucarelli, P., Berger, E., ANTONY, P., GLAAB, E., Hankemeier, T., Klein, C., SAUTER, T., SINKKONEN, L., & SCHWAMBORN, J. C. (2019). Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2019.09.018
Peer Reviewed verified by ORBi

BOLOGNIN, S., Fossépré, M., Qing, X., JARAZO, J., Ščančar, J., LUCUMI MORENO, E., NICKELS, S., WASNER, K., OUZREN, N., WALTER, J., GRÜNEWALD, A., GLAAB, E., Salamanca, L., Fleming, R. M. T., ANTONY, P., & SCHWAMBORN, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927
Peer Reviewed verified by ORBi

NICKELS, S. (2017). Stem cells for modeling Parkinson's disease [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/32753

WALTER, J., NICKELS, S., & SCHWAMBORN, J. C. (2017). Human induced pluripotent stem cell-derived neuronal progenitors are a suitable and effective drug discovery model for neurological mtDNA disorders. Stem Cell Investigation. doi:10.21037/sci.2017.11.08
Peer reviewed

ARIAS, J., JARAZO, J., QING, X., WALTER, J., GOMEZ GIRO, G., NICKELS, S., Zaehres, H., Schoeler, H. R., & SCHWAMBORN, J. C. (2017). FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling. Stem Cell Reports. doi:10.1016/j.stemcr.2017.08.026
Peer Reviewed verified by ORBi

Palm, T., BOLOGNIN, S., MEISER, J., NICKELS, S., Traeger, C., Meilenbrock, R.-L., Brockhaus, J., Streitmueller, M., Missler, M., & SCHWAMBORN, J. C. (2015). Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Scientific Reports, 5. doi:10.1038/srep16321
Peer Reviewed verified by ORBi

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