![]() ![]() | Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., BACKES, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de Las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., MICHELUCCI, A., NAZAROV, P., NICLOU, S. P., Nocentini, G., OLLERT, M., ... Poli, A. (2024). AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus-A joint EAACI-EANO position paper. Allergy. doi:10.1111/all.15994 ![]() |
Yabo, Y. A., Moreno-Sanchez, P. M., Pires-Afonso, Y., Kaoma, T., Nosirov, B., Scafidi, A., Ermini, L., Lipsa, A., Oudin, A., KYRIAKIS, D., GRZYB, K., POOVATHINGAL, S. K., Poli, A., Muller, A., TOTH, R., KLINK, B., BERCHEM, G. J. M. J., Berthold, C., HERTEL, F., ... GOLEBIEWSKA, A. (2023). Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/60199. doi:10.1101/2023.03.05.531162 |
![]() ![]() | Poli, A., Oudin, A., Muller, A., Salvato, I., Scafidi, A., Hunewald, O., Domingues, O., NAZAROV, P., Puard, V., Baus, V., AZUAJE, F., DITTMAR, G., ZIMMER, J., MICHEL, T., MICHELUCCI, A., NICLOU, S. P., & OLLERT, M. (March 2023). Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice. Allergy, 78 (3), 682-696. doi:10.1111/all.15545 ![]() |
![]() ![]() | Pires-Afonso, Y., Muller, A., GRZYB, K., Oudin, A., Yabo, Y. A., SOUSA, C., Scafidi, A., Poli, A., COSMA, A., HALDER, R., COOWAR, D., GOLEBIEWSKA, A., SKUPIN, A., NICLOU, S. P., & MICHELUCCI, A. (September 2022). Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency. Molecular Oncology, 16 (17), 3167 - 3191. doi:10.1002/1878-0261.13287 ![]() |
![]() ![]() | GARCIA, P., Wemheuer, W., Uriarte, O., MICHELUCCI, A., Masuch, A., Brioschi, S., Weihofen, A., KONCINA, E., COOWAR, D., HEURTAUX, T., GLAAB, E., BALLING, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., ... BUTTINI, M. (2022). Neurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease. Glia. doi:10.1002/glia.24149 ![]() |
![]() ![]() | Oudin, A., Baus, V., Barthelemy, V., Fabian, C., KLEIN, E., Dieterle, M., Wantz, M., Hau, A.-C., DORDING, C., Bernard, A., MICHELUCCI, A., Yabo, Y. A., Kanli, G., Keunen, O., Bjerkvig, R., NICLOU, S. P., & GOLEBIEWSKA, A. (18 June 2021). Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors. STAR Protocols, 2 (2), 100534. doi:10.1016/j.xpro.2021.100534 ![]() |
![]() ![]() | GRANDBARBE, L., MICHELUCCI, A., HEUSCHLING, P., PAVLOU, M. A., & GINOLHAC, A. (2021). NF-κB and TNF Affect the Astrocytic Differentiation from Neural Stem Cells. Cells. doi:10.3390/cells10040840 ![]() |
![]() ![]() | GOLEBIEWSKA, A., Hau, A.-C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., MICHELUCCI, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., AZUAJE, F., De Falco, A., Flies, B., ... NICLOU, S. (2020). Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology. Acta Neuropathologica. doi:10.1007/s00401-020-02226-7 ![]() |
![]() ![]() | GUI, Y., Thomas, M. H., Garcia, P., Karout, M., HALDER, R., MICHELUCCI, A., Kollmus, H., Zhou, C., Melmed, S., Schughart, K., BALLING, R., MITTELBRONN, M., Nadeau, J. H., Williams, R. W., SAUTER, T., BUTTINI, M., & SINKKONEN, L. (2020). Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging. Frontiers in Genetics. doi:10.3389/fgene.2020.566734 ![]() |
![]() ![]() | GOLEBIEWSKA, A., Hau, A.-C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., MICHELUCCI, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., AZUAJE, F., De Falco, A., Flies, B., ... NICLOU, S. (2020). Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/43022. doi:10.1101/2020.04.24.057802 |
![]() ![]() | Pires-Afonso, Y., NICLOU, S. P., & MICHELUCCI, A. (21 January 2020). Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma. International Journal of Molecular Sciences, 21 (3). doi:10.3390/ijms21030689 ![]() |
![]() ![]() | Dirkse, A., Golebiewska, A., Buder, T., Nazarov, P. V., Muller, A., Poovathingal, S., Brons, N. H. C., Leite, S., Sauvageot, N., Sarkisjan, D., Seyfrid, M., Fritah, S., Stieber, D., MICHELUCCI, A., Herold-Mende, C., Bjerkvig, R., Azuaje, F., SKUPIN, A., Deutsch, A., ... Hertel, F. (2019). Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment. Nature communications, 10 (1), 1787. doi:10.1038/s41467-019-09853-z ![]() |
![]() ![]() | PAVLOU, M. A., GRANDBARBE, L., Buckley, N., NICLOU, S., & MICHELUCCI, A. (2018). Transcriptional and epigenetic mechanisms underlying astrocyte identity. Progress in Neurobiology. doi:10.1016/j.pneurobio.2018.12.007 ![]() |
![]() ![]() | SOUSA, C., Golebiewska, A., Poovathingal, S. K., Kaoma, T., Pires-Afonso, Y., Martina, S., COOWAR, D., Azuaje, F., SKUPIN, A., BALLING, R., Biber, K., NICLOU, S., & MICHELUCCI, A. (2018). Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures. EMBO Reports. doi:10.15252/embr.201846171 ![]() |
![]() ![]() | DEL SOL MESA, A., RAVICHANDRAN, S., & MICHELUCCI, A. (2018). Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease. Frontiers in Physiology. ![]() |
![]() ![]() | SOUSA, C., Biber, K., & MICHELUCCI, A. (2017). Cellular and Molecular Characterization of Microglia: A Unique Immune Cell Population. Frontiers in Immunology, 8, 198. doi:10.3389/fimmu.2017.00198 ![]() |
![]() ![]() | ANTONY, P., TALLAM, A., PERUMAL, T. M., Jäger, C., FRITZ, J., BALLING, R., DEL SOL MESA, A., MICHELUCCI, A., & Vallar, L. (2016). Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages. PLoS ONE. doi:10.1371/journal.pone.0149050 ![]() |
![]() ![]() | Cordes, T., Wallace, M., MICHELUCCI, A., Divakaruni, A. S., Sapcariu, S. C., SOUSA, C., Koseki, H., Cabrales, P., Murphy, A. N., Hiller, K., & Metallo, C. M. (2016). Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels. The Journal of biological chemistry, 291 (27), 14274-84. doi:10.1074/jbc.m115.685792 ![]() |
![]() ![]() | MEISER, J., DELCAMBRE, S., WEGNER, A., Jäger, C., GHELFI, J., FOUQUIER DU0027HÉROUËL, A., DONG, X., WEINDL, D., Stautner, C., NONNENMACHER, Y., MICHELUCCI, A., Popp, O., Giesert, F., Schildknecht, S., KRAEMER, L., Schneider, J. G., Woitalla, D., Wurst, W., SKUPIN, A., ... HILLER, K. (2016). Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism. Neurobiology of Disease, 89, 112-125. doi:10.1016/j.nbd.2016.01.019 ![]() |
![]() ![]() | BIRCK, C., KONCINA, E., HEURTAUX, T., GLAAB, E., MICHELUCCI, A., HEUSCHLING, P., & GRANDBARBE, L. (10 November 2015). Transcriptomic analyses of primary astrocytes under TNFα treatment. Genomics Data, 7, 7-11. doi:10.1016/j.gdata.2015.11.005 ![]() |
![]() ![]() | Gabel, S., KONCINA, E., Dorban, G., HEURTAUX, T., BIRCK, C., GLAAB, E., MICHELUCCI, A., HEUSCHLING, P., & Grandbarbe, L. (17 September 2015). Inflammation Promotes a Conversion of Astrocytes into Neural Progenitor Cells via NF-κB Activation. Molecular Neurobiology, 53 (8), 5041-5055. doi:10.1007/s12035-015-9428-3 ![]() |
![]() ![]() | Jäger, C.* , GLAAB, E.* , MICHELUCCI, A.* , Binz, T., Köglsberger, S., GARCIA, P., TREZZI, J.-P., GHELFI, J., BALLING, R., & BUTTINI, M. (2015). The Mouse Brain Metabolome: Region-Specific Signatures and Response to Excitotoxic Neuronal Injury. American Journal of Pathology, 185 (6), 1699-1712. doi:10.1016/j.ajpath.2015.02.016 ![]() * These authors have contributed equally to this work. |
![]() ![]() | MICHELUCCI, A., Bithell, A., Burney, M., Johnston, C., Wong, K.-Y., Teng, S.-W., Desai, J., Gumbleton, N., Anderson, G., Stanton, L., Williams, B., & Buckley, N. (2015). The Neurogenic Potential of Astrocytes Is Regulated by Inflammatory Signals. Molecular Neurobiology. doi:10.1007/s12035-015-9296-x ![]() |
![]() ![]() | Cordes, T., MICHELUCCI, A., & HILLER, K. (2015). Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite. Annual review of nutrition. doi:10.1146/annurev-nutr-071714-034243 ![]() |
![]() ![]() | MICHELUCCI, A., CORDES, T., GHELFI, J., PAILOT, A., Reiling, N., Goldmann, O., Binz, T., WEGNER, A., TALLAM, A., Rausell, A., BUTTINI, M., LINSTER, C., Medina, E., BALLING, R., & HILLER, K. (2013). Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1218599110 ![]() |
![]() ![]() | WEGNER, A., CORDES, T., MICHELUCCI, A., & HILLER, K. (2012). The Application of Stable Isotope Assisted Metabolomics in Biomedicine. Current Biotechnology, 1, 88-97. ![]() |
![]() ![]() | HEURTAUX, T., MICHELUCCI, A., LOSCIUTO, S., Gallotti, C., FELTEN, P., Dorban, G., GRANDBARBE, L., MORGA, E., & HEUSCHLING, P. (July 2010). Microglial activation depends on beta-amyloid conformation: role of the formylpeptide receptor 2. Journal of Neurochemistry, 114 (2), 576-586. doi:10.1111/j.1471-4159.2010.06783.x ![]() |
![]() ![]() | MICHELUCCI, A., HEURTAUX, T., GRANDBARBE, L., MORGA, E., & HEUSCHLING, P. (2009). Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta. Journal of Neuroimmunology, 210 (1-2), 3-12. doi:10.1016/j.jneuroim.2009.02.003 ![]() |
![]() ![]() | Hauss, F., Liu, J., MICHELUCCI, A., Coowar, D., MORGA, E., HEUSCHLING, P., & Luu, B. (2007). Dual bioactivity of resveratrol fatty alcohols: differentiation of neural stem cells and modulation of neuroinflammation. Bioorganic & Medicinal Chemistry Letters, 17 (15), 4218-4222. doi:10.1016/j.bmcl.2007.05.037 ![]() |
![]() ![]() | GRANDBARBE, L., MICHELUCCI, A., HEURTAUX, T., Hemmer, K., MORGA, E., & HEUSCHLING, P. (2007). Notch signaling modulates the activation of microglial cells. Glia, 55 (15), 1519-30. doi:10.1002/glia.20553 ![]() |