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CRAWFORD Alexander Dettmar

Main Referenced Co-authors
CORDERO MALDONADO, Maria Lorena  (6)
Esguerra, C. V. (5)
LINSTER, Carole  (4)
Cordero-Maldonado, M. L. (3)
Cordero-Maldonado, Maria Lorena (3)
Main Referenced Keywords
Animals (7); Zebrafish (7); Danio rerio (3); Disease Models, Animal (3); Larva (3);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Chemical Biology (Crawford Group) (7)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (2)
Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group) (1)
Luxembourg Centre for Systems Biomedicine (LCSB): Enzymology & Metabolism (Linster Group) (1)
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) (1)
Main Referenced Disciplines
Human health sciences: Multidisciplinary, general & others (8)
Life sciences: Multidisciplinary, general & others (5)
Neurology (4)
Biochemistry, biophysics & molecular biology (3)
Biotechnology (1)

Publications (total 19)

The most downloaded
1094 downloads
Crawford, A. D., Jaspars, M., De Pascale, D., Andersen, J. H., Reyes, F., & Ianora, A. (February 2016). The marine biodiscovery pipeline and ocean medicines of tomorrow. Journal of the Marine Biological Association of the United Kingdom, 96 (01), 151-158. doi:10.1017/S0025315415002106 https://hdl.handle.net/10993/27307

The most cited

176 citations (Scopus®)

Suls, A., Jaehn, J. A., Kecskés, A., Weber, Y., Weckhuysen, S., Craiu, D. C., Siekierska, A., Djémie, T., Afrikanova, T., Gormley, P., Von Spiczak, S., Kluger, G., Iliescu, C. M., Talvik, T., Talvik, I., Meral, C., Caglayan, H. S., Giraldez, B. G., Serratosa, J., ... Helbig, I. (2013). De novo loss-of-function mutations in CHD2 cause a fever-sensitive myoclonic epileptic encephalopathy sharing features with dravet syndrome. American Journal of Human Genetics, 93 (5), 967-975. doi:10.1016/j.ajhg.2013.09.017 https://hdl.handle.net/10993/27271

HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Merino Ruiz, C., PATRASKAKI, M., Gomez-Giro, G., Kleine Borgmann, F., Meyer, M., Carpentier, A., WARMOES, M. O., Jäger, C., MITTELBRONN, M., SCHWAMBORN, J. C., Cordero-Maldonado, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (March 2024). CLN3 deficiency leads to neurological and metabolic perturbations during early development. Life Science Alliance, 7 (3). doi:10.26508/lsa.202302057
Peer Reviewed verified by ORBi

MARTINS, T., SOLIMAN, R., Cordero-Maldonado, M. L., DONATO, C., AMELI, C., MOMBAERTS, L., SKUPIN, A., Peri, F., & CRAWFORD, A. (September 2023). Seizure-induced increase in microglial cell population in the developing zebrafish brain. Epilepsy Research, 195, 107203. doi:10.1016/j.eplepsyres.2023.107203
Peer Reviewed verified by ORBi

HEINS MARROQUIN, U., SINGH, R., PERATHONER, S., GAVOTTO, F., Ruiz, C. M., PATRASKAKI, M., Gomez-Giro, G., Borgmann, F. K., Meyer, M., Carpentier, A., WARMOES, M. O., JÄGER, C., MITTELBRONN, M., SCHWAMBORN, J. C., CORDERO MALDONADO, M. L., CRAWFORD, A., SCHYMANSKI, E., & LINSTER, C. (2023). CLN3 deficiency leads to neurological and metabolic perturbations during early development. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/57737. doi:10.1101/2023.03.17.533107

Mhlongo, F., Cordero Maldonado, M. L., Crawford, A., Katerere, D., Sandasi, M., Hattingh, A. C., Koekemoer, T. C., Van de Venter, M., & Viljoen, A. M. (March 2022). Evaluation of the wound healing properties of South African medicinal plants using zebrafish and in vitro bioassays. Journal of Ethnopharmacology, 286. doi:10.1016/j.jep.2021.114867
Peer Reviewed verified by ORBi

Chipiti, T., Viljoen M., A., Cordero Maldonado, M. L., Veale G L, C., Van Heerden, F., Sandasi, M., Chen, W., Crawford, A., & Enslin, G. (October 2021). Anti-seizure activity of African medicinal plants: The identification of bioactive alkaloids from the stem bark of Rauvolfia caffra using an in vivo zebrafish model. Journal of Ethnopharmacology, 28 (279). doi:10.1016/j.jep.2021.114282
Peer Reviewed verified by ORBi

Soliman, R., Cordero Maldonado, M. L., Martins, T., Moein, M., Conrotte, J.-F., Warmack, R., Skupin, A., Crawford, A., Clarke, S., & Linster, C. (2020). L-Isoaspartyl methyltransferase deficiency in zebrafish leads to impaired calcium signaling in the brain. Frontiers in Genetics. doi:10.3389/fgene.2020.612343
Peer Reviewed verified by ORBi

Heins Marroquin, U., Jung, P., Cordero Maldonado, M. L., Crawford, A., & Linster, C. (27 September 2019). Phenotypic assays in yeast and zebrafish reveal drugs that rescue ATP13A2 deficiency. Brain Communications, 1 (1), 2-17. doi:10.1093/braincomms/fcz019
Peer Reviewed verified by ORBi

Moein, M., Grzyb, K., Gonçalves Martins, T., Komoto, S., Peri, F., Crawford, A. D., Fouquier d’Herouel, A., & Skupin, A. (2018). CaSiAn: a Calcium Signaling Analyzer tool. Bioinformatics, 1, 3. doi:10.1093/bioinformatics/bty281
Peer reviewed

Köglsberger, S., Cordero Maldonado, M. L., Antony, P., Forster, J., Garcia, P., Buttini, M., Crawford, A. D., & Glaab, E. (December 2017). Gender-specific expression of ubiquitin-specific peptidase 9 modulates tau expression and phosphorylation: possible implications for tauopathies. Molecular Neurobiology, 54 (10), 7979–7993. doi:10.1007/s12035-016-0299-z
Peer Reviewed verified by ORBi

Crawford, A. D., Jaspars, M., De Pascale, D., Andersen, J. H., Reyes, F., & Ianora, A. (February 2016). The marine biodiscovery pipeline and ocean medicines of tomorrow. Journal of the Marine Biological Association of the United Kingdom, 96 (01), 151-158. doi:10.1017/S0025315415002106
Peer Reviewed verified by ORBi

Zhang, Y., Kecskés, A., Copmans, D., Langlois, M., Crawford, A. D., Ceulemans, B., Lagae, L., De Witte, P. A. M., & Esguerra, C. V. (2015). Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: Inhibition of epileptic seizures by the serotonin agonist fenfluramine. PLoS ONE, 10 (5). doi:10.1371/journal.pone.0125898
Peer Reviewed verified by ORBi

Leclercq, K., Afrikanova, T., Langlois, M., De Prins, A., Buenafe, O. E., Rospo, C. C., Van Eeckhaut, A., de Witte, P. A. M., Crawford, A. D., Smolders, I., Esguerra, C. V., & Kaminski, R. M. (2015). Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish. Epilepsy & behavior : E&B, 45, 53-63. doi:10.1016/j.yebeh.2015.03.019
Peer reviewed

Galizia, E. C., Myers, C. T., Leu, C., de Kovel, C. G. F., Afrikanova, T., Cordero-Maldonado, M. L., Martins, T., Jacmin, M., Drury, S., Krishna Chinthapalli, V., Muhle, H., Pendziwiat, M., Sander, T., Ruppert, A.-K., Møller, R. S., Thiele, H., Krause, R., Schubert, J., Lehesjoki, A.-E., ... Sisodiya, S. M. (2015). CHD2 variants are a risk factor for photosensitivity in epilepsy. Brain: a Journal of Neurology. doi:10.1093/brain/awv052
Peer reviewed

Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J. R., de Kovel, C. G. F., Thiele, H., Konrad, K., Kawalia, A., Toliat, M. R., Sander, T., Ruschendorf, F., Caliebe, A., Nagel, I., Kohl, B., ... Lerche, H. (02 November 2014). Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. Nature Genetics, 46 (12), 1327-32. doi:10.1038/ng.3130
Peer Reviewed verified by ORBi

Carballeira, N. M., Bwalya, A. G., Itoe, M. A., Andricopulo, A. D., Cordero-Maldonado, M. L., Kaiser, M., Mota, M. M., Crawford, A. D., Guido, R. V. C., & Tasdemir, D. (2014). 2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes. Bioorganic & Medicinal Chemistry Letters, 24 (17), 4151-4157. doi:10.1016/j.bmcl.2014.07.050
Peer reviewed

Cordero-Maldonado, M. L., Siverio-Mota, D., Vicet-Muro, L., Wilches-Arizábala, I. M., Esguerra, C. V., de Witte, P. A. M., & Crawford, A. D. (2013). Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites. PLoS ONE, 8 (10). doi:10.1371/journal.pone.0075404
Peer Reviewed verified by ORBi

Buenafe, O. E., Orellana-Paucar, A., Maes, J., Huang, H., Ying, X., De Borggraeve, W., Crawford, A. D., Luyten, W., Esguerra, C. V., & De Witte, P. (2013). Tanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models. ACS Chemical Neuroscience, 4 (11), 1479-1487. doi:10.1021/cn400140e
Peer reviewed

Gebruers, E., Cordero-Maldonado, M. L., Gray, A. I., Clements, C., Harvey, A. L., Edrada-Ebel, R., De Witte, P. A. M., Crawford, A. D., & Esguerra, C. V. (2013). A phenotypic screen in zebrafish identifies a novel small-molecule inducer of ectopic tail formation suggestive of alterations in non-canonical Wnt/PCP signaling. PLoS ONE, 8 (12). doi:10.1371/journal.pone.0083293
Peer Reviewed verified by ORBi

Suls, A., Jaehn, J. A., Kecskés, A., Weber, Y., Weckhuysen, S., Craiu, D. C., Siekierska, A., Djémie, T., Afrikanova, T., Gormley, P., Von Spiczak, S., Kluger, G., Iliescu, C. M., Talvik, T., Talvik, I., Meral, C., Caglayan, H. S., Giraldez, B. G., Serratosa, J., ... Helbig, I. (2013). De novo loss-of-function mutations in CHD2 cause a fever-sensitive myoclonic epileptic encephalopathy sharing features with dravet syndrome. American Journal of Human Genetics, 93 (5), 967-975. doi:10.1016/j.ajhg.2013.09.017
Peer reviewed

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