A fin loop-like structure in GPX4 affords neuroprotection

Lorenz, S. M.; Wahida, A.; Bostock, M. J.; Seibt, T.; Santos Dias Mourão, A.; Levkina, A.; Trümbach, D.; Soudy, M.; Emler, D.; Rothammer, N.; Woo, M. S.; Sonner, J. K.; Novikova, M.; Henkelmann, B.; Aldrovandi, M.; Kaemena, D.; Vermonden, P.; Mishima, E.; Nakamura, T.; Ito, J.; Doll, S.; Proneth, B.; Bürkle, E.; Rizzollo, F.; Escamilla Ayala, A.; Napolitano, V.; Kolonko-Adamska, M.; Gaussmann, S.; Merl-Pham, J.; Hauck, S.; Pertek, A.; Rusha, E.; van San, E.; Vanden Berghe, T.; Hass, D.; Maida, A.; Frenz, J. M.; Pedrera, L.; Dolga, A.; Kraiger, M.; Hrabé de Angelis, M.; Fuchs, H.; Ebert, G.; Lenberg, J.; Friedman, J.; Scale, C.; Agostinis, P.; Zimprich, A.; Vogt-Weisenhorn, D.; Garrett, L.; Hölter, S. M.; Wurst, W.; GLAAB, Enrico; Lewerenz, J.; Popper, B.; Sieben, C.; Steinacker, P.; Zischka, H.; Garcia-Saez, A. J.; Tietze, A.; Ramesh, S. K.; Ayton, S.; Vincendeau, M.; Friese, M. A.; Wigby, K.; Sattler, M.; Mann, M.; Ingold, I.; Jayavelu, A. K.; Popowicz, G. M.; Conrad, M.

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Article (Scientific journals)

A fin loop-like structure in GPX4 affords neuroprotection

Lorenz, S. M.; Wahida, A.; Bostock, M. J. et al.

2025 • In Cell, in press (in press)

Peer Reviewed verified by ORBi

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https://hdl.handle.net/10993/66478

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Keywords :

GPX4; inflammation; neuroprotection; ferroptosis; Alzheimer's disease; mouse models; Parkinson's disease; Huntington's disease; neurodegeneration; iPSCs; peroxidation; neuroproteomics

Research center :

Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group)

Disciplines :

Neurology
Human health sciences: Multidisciplinary, general & others
Biotechnology
Life sciences: Multidisciplinary, general & others

Author, co-author :

Lorenz, S. M.

Wahida, A.

Bostock, M. J.

Seibt, T.

Santos Dias Mourão, A.

Levkina, A.

Trümbach, D.

Soudy, M.

Emler, D.

Rothammer, N.

More authors (61 more)

External co-authors :

yes

Language :

English

Title :

A fin loop-like structure in GPX4 affords neuroprotection

Publication date :

2025

Journal title :

Cell

ISSN :

0092-8674

eISSN :

1097-4172

Volume :

in press

Issue :

in press

Pages :

in press

Peer reviewed :

Peer Reviewed verified by ORBi

Focus Area :

Systems Biomedicine

Development Goals :

3. Good health and well-being

Available on ORBilu :

since 25 November 2025

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