Improved awareness of physical activities is associated with a gain of fitness and a stable body weight in breast cancer patients during the first year of antineoplastic therapy: the BEGYN-1 study.
Zemlin, Cosima; Schleicher, Julia Theresa; Altmayer, Lauraet al.
COVID - 19; MET; body composition; breast cancer; fitness tracker; physical activity; resting heart rate; weight; Oncology; Cancer Research; COVID; 19
Abstract :
[en] [en] BACKGROUND: Breast cancer is the most frequent cancer in women. Reduced physical activity and overweight are associated with poor prognosis. Breast cancer patients have a high risk to gain weight, lose muscle mass and reduce physical activity during therapy. Concepts are urgently needed to motivate patients to engage in physical activity.
METHODS: 110 non-metastatic breast cancer patients were included in the prospective observational BEGYN-1 study. Physiological parameters and body composition were measured before the start of therapy and then quarterly for one year. Patients used a fitness tracker and documented their physical activity in a diary throughout the study.
RESULTS: Although the patients were not offered any guided exercise, and despite the restrictions during the COVID-19 pandemic, they increased their physical activity (metabolic equivalent of task (MET) -minutes): p<0.001), physical fitness (decreasing resting heart rate: p=0.001) and did not gain weight (median - 0.4kg) over the course of the study.
CONCLUSION: Improved awareness of physical activity is associated with an increase in physical activity, fitness, and a stable weight during the first year of therapy in breast cancer patients. Counselling at diagnosis should motivate patients to engage in physical activity, wear a fitness tracker and document activities.
Disciplines :
Oncology
Author, co-author :
Zemlin, Cosima ; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Schleicher, Julia Theresa; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Altmayer, Laura; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Stuhlert, Caroline; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Wörmann, Carolin; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Lang, Marina; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Scherer, Laura-Sophie; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Thul, Ida Clara; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Spenner, Lisanne Sophie; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Simon, Jana Alisa; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Wind, Alina; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Kaiser, Elisabeth ; Department of General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Saar, Germany
Weber, Regine ; Department of General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Saar, Germany
Goedicke-Fritz, Sybelle; Department of General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Saar, Germany
Wagenpfeil, Gudrun; Institute for Medical Biometry, Epidemiology and Medical Informatics (IMBEI), Saarland University Campus Homburg, Homburg, Saar, Germany
Zemlin, Michael; Department of General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Saar, Germany
STEFFGEN, Georges ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > Department of Behavioural and Cognitive Sciences (DBCS) > Health and Behaviour
Solomayer, Erich-Franz; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany
Müller, Carolin; Department of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Saar, Germany ; Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH, United States
Improved awareness of physical activities is associated with a gain of fitness and a stable body weight in breast cancer patients during the first year of antineoplastic therapy: the BEGYN-1 study.
Publication date :
2023
Journal title :
Frontiers in Oncology
eISSN :
2234-943X
Publisher :
Frontiers Media SA, Switzerland
Volume :
13
Pages :
1198157
Peer reviewed :
Peer Reviewed verified by ORBi
Funding text :
This work was supported by miteinander gegen Krebs e.V. (to CZ), by a grant from the federal state of Saarland (to CM and CZ, grant number W/2 - LFFP 21/13) and by intramural funds of the Saarland University Medical Center. AcknowledgmentsThe authors would like to thank Dr. Maria Cacacciola-Ketter, Cross against Cancer – miteinander gegen Krebs e.V., Bernd Neuhardt (Laufschule Saarpfalz, Runners Gym Zweibrücken). Furthermore, we acknowledge support by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) and Saarland University within the “Open Access Publication Funding” program.
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