Bioimaging; Biosensing; Nano-plasmonics; Optical microscopy; Ultrafast laser spectroscopy; Bio-imaging; Biomolecular interactions; Cross-disciplinary; Interaction phenomena; Life-sciences; Native environment; Physical science; Space and time; Electronic, Optical and Magnetic Materials; Atomic and Molecular Physics, and Optics
Résumé :
[en] In the quest to decipher the chain of life from molecules to cells, the biological and biophysical questions being asked increasingly demand techniques that are capable of identifying specific biomolecules in their native environment, and can measure biomolecular interactions quantitatively, at the smallest possible scale in space and time, without perturbing the system under observation. The interaction of light with biomolecules offers a wealth of phenomena and tools that can be exploited to drive this progress. This Roadmap is written collectively by prominent researchers and encompasses selected aspects of bio-nano-photonics, spanning from the development of optical micro/nano-spectroscopy technologies for quantitative bioimaging and biosensing to the fundamental understanding of light–matter interaction phenomena with biomolecules at the nanoscale. It will be of interest to a wide cross-disciplinary audience in the physical sciences and life sciences.
Disciplines :
Physique
Auteur, co-auteur :
Herkert, Ediz; ICFO—Institut de Ciencies Fotoniques, Barcelona Institute of Science and Technology, Barcelona, Spain
Slesiona, Nicole; School of Biosciences, Cardiff University, Cardiff, United Kingdom
Recchia, Martina Elisena; School of Biosciences, Cardiff University, Cardiff, United Kingdom
DECKERT, Thomas ; University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Physics and Materials Science (DPHYMS)
Garcia-Parajo, Maria F. ; ICFO—Institut de Ciencies Fotoniques, Barcelona Institute of Science and Technology, Barcelona, Spain ; ICREA, Barcelona, Spain
Fantuzzi, Eric Michele; Aix Marseille Univ, CNRS, Centrale Marseille, Institut Fresnel, Marseille, France
Pruccoli, Andrea; Department Chemie, Universität Konstanz, Konstanz, Germany
Ragupathy, Imaiyan Chitra; Department Chemie, Universität Konstanz, Konstanz, Germany
Gudavičius, Dominykas; Light Conversion, Vilnius, Lithuania ; School of Physics and Astronomy, Cardiff University, Cardiff, United Kingdom
Rigneault, Hervé ; Aix Marseille Univ, CNRS, Centrale Marseille, Institut Fresnel, Marseille, France
Majer, Jan; GSK Medicines Research Centre, Stevenage, United Kingdom
Zumbusch, Andreas; Department Chemie, Universität Konstanz, Konstanz, Germany
Munger, Eleanor; Aix Marseille Univ, CNRS, Centrale Marseille, Institut Fresnel, Marseille, France
Brasselet, Sophie ; Aix Marseille Univ, CNRS, Centrale Marseille, Institut Fresnel, Marseille, France
Jones, Arwyn T. ; GSK Medicines Research Centre, Stevenage, United Kingdom
Watson, Peter ; School of Biosciences, Cardiff University, Cardiff, United Kingdom
Boppart, Stephen A. ; University of Illinois at Urbana-Champaign, Champaign, United States
Singh, Vikramdeep; School of Physics and Astronomy, Cardiff University, Cardiff, United Kingdom
Borkar, Saurabh; ICFO—Institut de Ciencies Fotoniques, Barcelona Institute of Science and Technology, Barcelona, Spain
Quintela Rodriguez, Frank E.; Dipartimento FIM, Università di Modena e Reggio Emilia, Modena, Italy ; Istituto Nanoscienze—CNR, Modena, Italy
Langbein, Wolfgang ; School of Physics and Astronomy, Cardiff University, Cardiff, United Kingdom
Petropoulos, Vasilis; IFN-CNR, Dipartimento di Fisica, Politecnico di Milano, Milano, Italy
van Hulst, Niek F. ; ICFO—Institut de Ciencies Fotoniques, Barcelona Institute of Science and Technology, Barcelona, Spain ; ICREA, Barcelona, Spain
Maiuri, Margherita ; IFN-CNR, Dipartimento di Fisica, Politecnico di Milano, Milano, Italy
Cerullo, Giulio ; IFN-CNR, Dipartimento di Fisica, Politecnico di Milano, Milano, Italy
BRIDA, Daniele ; University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Physics and Materials Science (DPHYMS)
The authors would like to thank Dr Lukas Kontenis and Ignas Stasevičius for their helpful advice. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 812992.
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