Amino Acid Motifs; Computer Graphics; Models, Molecular; Models, Theoretical; Protein Interaction Domains and Motifs; Proteins/chemistry
Résumé :
[en] The unique representation of proteins becomes more and more important with the growing number of known protein structure data. Graph-theory provides many methods not only for the description but also for comparison and classification of protein structures. Here, we describe a graph-theoretical modeling approach of the protein supersecondary structure. The resulting linear notations are intuitive and can be used to find common substructures very fast and easily. We illustrate the necessary definitions by biological examples and discuss the representation of various supersecondary structure motifs.
Centre de recherche :
- Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group)
Disciplines :
Biochimie, biophysique & biologie moléculaire
Auteur, co-auteur :
Koch, Ina
Kreuchwig, Annika
MAY, Patrick ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Co-auteurs externes :
yes
Langue du document :
Anglais
Titre :
Hierarchical representation of supersecondary structures using a graph-theoretical approach.
