Title : The gut microbiome molecular complex in human health and disease
Language : English
Author, co-author : Wilmes, Paul [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology >]
Martin-Gallausiaux, Camille [Institut Pasteur, Paris > Evolutionary Biology of the Microbial Cell]
Ostaszewski, Marek [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Bioinformatics Core >]
Aho, Velma [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology >]
Novikova, Polina [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology]
Laczny, Cedric Christian [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology >]
Schneider, Jochen [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Medical Translational Research >]
Publication date : 14-Sep-2022
Journal title : Cell Host and Microbe
Publisher : Cell Press
Volume : 30
Issue/season : 9
Pages : 1201-1206
Peer reviewed : Yes
Audience : International
ISSN : 1931-3128
e-ISSN : 1934-6069
City : Cambridge
Country : United States - Massachusetts
Keywords : [en] microbiome ; inflammation ; biomolecules
Abstract : [en] The human gut microbiome produces a functional complex of biomolecules, including nucleic acids, (poly) peptides, structural molecules, and metabolites. This impacts human physiology in multiple ways, especially by triggering inflammatory pathways in disease. At present, much remains to be learned about the identity of key effectors and their causal roles.
Research centres : Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group)
Target : Researchers
Permalink : http://hdl.handle.net/10993/53954
DOI : 10.1016/j.chom.2022.08.016
Other URL : https://www.sciencedirect.com/science/article/pii/S1931312822004152
Framework Programme / European Project : H2020 ; 863664 - ExpoBiome - Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease
FnR project : FnR ; FNR11333923 > Paul Wilmes > MiBiPa > Non-invasive Microbiome-derived Multi-omic Biomarkers For The Early-stage Detection And Stratification Of Parkinson’S Disease > 01/09/2017 > 28/02/2021 > 2016