The gut microbiome molecular complex in human health and disease

[en] The human gut microbiome produces a functional complex of biomolecules, including nucleic acids, (poly) peptides, structural molecules, and metabolites. This impacts human physiology in multiple ways, especially by triggering inflammatory pathways in disease. At present, much remains to be learned about the identity of key effectors and their causal roles.

Research center :

- Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group)

Disciplines :

Microbiology

Author, co-author :

Wilmes, Paul ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

Martin-Gallausiaux, Camille; Institut Pasteur, Paris > Evolutionary Biology of the Microbial Cell

Ostaszewski, Marek ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Bioinformatics Core

Aho, Velma ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

Novikova, Polina ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

Laczny, Cedric Christian ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology

Schneider, Jochen ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Medical Translational Research

External co-authors :

yes

Language :

English

Title :

The gut microbiome molecular complex in human health and disease

Publication date :

14 September 2022

Journal title :

Cell Host and Microbe

ISSN :

1934-6069

Publisher :

Cell Press, Cambridge, United States - Massachusetts

Volume :

Issue :

Pages :

1201-1206

Peer reviewed :

Peer Reviewed verified by ORBi

Focus Area :

Systems Biomedicine

Additional URL :

https://www.sciencedirect.com/science/article/pii/S1931312822004152

European Projects :

H2020 - 863664 - ExpoBiome - Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease

FnR Project :

FNR11333923 - Non-invasive Microbiome-derived Multi-omic Biomarkers For The Early-stage Detection And Stratification Of Parkinson'S Disease, 2016 (01/09/2017-28/02/2021) - Paul Wilmes

Funders :

CE - Commission Européenne [BE]

Available on ORBilu :

since 19 January 2023

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Bibliography

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