Reference : Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduc...
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduces caregivers’ fear of hypoglycemia and improves their well-being
de Beaufort, Carine [University of Luxembourg > > >]
Schierloh, Ulrike []
Thankamony, A. []
Ware, J. []
Wilinska, M.E. []
Fröhlich-Reiterer, E. []
Kapellen, T.M. []
Rami-Merhar []
Hofer, S.E. []
Campbell, F.M. []
Bocchino, L.E. []
Lawton, J. []
Rioze, S. []
Hood, K. []
Frisch, M. []
Thiele, A. []
Allen, J. []
Boughton, C. []
Hovorka, R. []
Pit-Ten Cate, Ineke mailto [University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > LUCET >]
Diabetes Care
American Diabetes Association
[en] Type 1 Diabetes ; closed loop insulin delivery ; Very young children
[en] Objective To evaluate the impact of CamAPS FX hybrid closed-loop automated insulin delivery (HCL) in very young children with type 1 diabetes (T1D) on caregivers’ well-being, fear of hypoglycemia and sleepiness.
Research Design Multinational, open label, randomized crossover study. Children (1-7years) with T1D received treatment for two 4-month periods in random order, comparing HCL with sensor augmented pump (SAP) (control). At baseline and after each treatment period, caregivers were invited to complete WHO-5, Hypoglycemia Fear Survey (HFS) and Epworth Sleepiness Scale (ESS).
Results Caregivers of 74 children (mean±SD: age 5±2 years; 42% female, baseline HbA1c 7.3±0.7%) participated. Results revealed significantly lower scores for hypoglycemia fear (p<.001) and higher for well-being (p<.001) after HCL treatment. A trend towards a reduction in sleepiness score was observed (p=0.09).
Our results suggest a better well-being and less hypoglycemia fear in caregivers of very young children with T1D on CamAPS FX HCL.
Researchers ; Professionals

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