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07 December 2022
Article (Scientific journals)
Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduces caregivers’ fear of hypoglycemia and improves their well-being
de Beaufort, Carine; Schierloh, Ulrike; Thankamony, A. et al.
2022In Diabetes Care, 45, p. 3050-3053
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Keywords :
Type 1 Diabetes; closed loop insulin delivery; Very young children
Abstract :
[en] Objective To evaluate the impact of CamAPS FX hybrid closed-loop automated insulin delivery (HCL) in very young children with type 1 diabetes (T1D) on caregivers’ well-being, fear of hypoglycemia and sleepiness. Research Design Multinational, open label, randomized crossover study. Children (1-7years) with T1D received treatment for two 4-month periods in random order, comparing HCL with sensor augmented pump (SAP) (control). At baseline and after each treatment period, caregivers were invited to complete WHO-5, Hypoglycemia Fear Survey (HFS) and Epworth Sleepiness Scale (ESS). Results Caregivers of 74 children (mean±SD: age 5±2 years; 42% female, baseline HbA1c 7.3±0.7%) participated. Results revealed significantly lower scores for hypoglycemia fear (p<.001) and higher for well-being (p<.001) after HCL treatment. A trend towards a reduction in sleepiness score was observed (p=0.09). Conclusion Our results suggest a better well-being and less hypoglycemia fear in caregivers of very young children with T1D on CamAPS FX HCL.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
de Beaufort, Carine ;  University of Luxembourg
Schierloh, Ulrike
Thankamony, A.
Ware, J.
Wilinska, M.E.
Fröhlich-Reiterer, E.
Kapellen, T.M.
Rami-Merhar
Hofer, S.E.
Campbell, F.M.
Bocchino, L.E.
Lawton, J.
Rioze, S.
Hood, K.
Frisch, M.
Thiele, A.
Allen, J.
Boughton, C.
Hovorka, R.
Pit-Ten Cate, Ineke ;  University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > LUCET
More authors (10 more) Less
External co-authors :
yes
Language :
English
Title :
Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduces caregivers’ fear of hypoglycemia and improves their well-being
Publication date :
04 October 2022
Journal title :
Diabetes Care
ISSN :
1935-5548
Publisher :
American Diabetes Association, Alexandria, United States - Virginia
Volume :
45
Pages :
3050-3053
Peer reviewed :
Peer Reviewed verified by ORBi

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