No full text
Article (Scientific journals)
Genotypic and antigenic characterization of hemagglutinin proteins of African measles virus isolates
Truong, A. T.; Kreis, Stephanie; Ammerlaan, W. et al.
1999In Virus Research, 62 (1), p. 89-95
Peer reviewed
 

Files


Full Text
No document available.

Send to



Details



Keywords :
Africa; Hemagglutinin; Measles virus; Monoclonal antibodies; Sequence
Abstract :
[en] A comprehensive phylogenetic study based on the hemagglutinin (H) protein of all known African measles virus (MV) isolates is presented. The study includes 64 new H gene sequences from Ghana, Nigeria and South Africa as well as viruses from Zambia and The Gambia for which only incomplete sequencing data were available and that have previously not been genotyped. The results provide further support to the tentative assignment of the Nigerian and Ghanaian viruses to a new genotype B3 within clade B. A distinct geographic distribution pattern emerged with clade B viruses circulating exclusively in African countries north of the equator. All MV strains from southern Africa grouped in clades A and D with the majority of viruses belonging to genotype D4. The viruses considerably differed by their sensitivity to neutralization by monoclonal antibodies (mAb), but three selected antibodies were sufficient to distinguish between African MVs representing four different genotypes. Copyright (C) 1999 Elsevier Science B.V.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Truong, A. T.;  Department of Virology, University College Hospital Ibadan, Ibadan, Nigeria
Kreis, Stephanie ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit
Ammerlaan, W.;  LVO, Rijksinstituut V. Volksgezondheid M., Bilthoven, Netherlands
Hartter, H. K.
Adu, F.
Omilabu, S. A.
Oyefolu, A. O.
Berbers, G. A. M.
Muller, Claude;  CRP-Santé Luxembourg
Language :
English
Title :
Genotypic and antigenic characterization of hemagglutinin proteins of African measles virus isolates
Publication date :
1999
Journal title :
Virus Research
ISSN :
0168-1702
Publisher :
Elsevier Science, Amsterdam, Netherlands
Volume :
62
Issue :
1
Pages :
89-95
Peer reviewed :
Peer reviewed
Commentary :
cited By (since 1996)38 Scopus
Available on ORBilu :
since 19 August 2013

Statistics


Number of views
69 (6 by Unilu)
Number of downloads
0 (0 by Unilu)

Scopus citations®
 
43
Scopus citations®
without self-citations
35
WoS citations
 
41

Bibliography


Similar publications



Contact ORBilu