Title : Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease Language : English Author, co-author : Sims, Rebecca [> >] van der Lee, Sven J. [> >] Naj, Adam C. [> >] Bellenguez, Celine [> >] Badarinarayan, Nandini [> >] Jakobsdottir, Johanna [> >] Kunkle, Brian W. [> >] Boland, Anne [> >] Raybould, Rachel [> >] Bis, Joshua C. [> >] Martin, Eden R. [> >] Grenier-Boley, Benjamin [> >] Heilmann-Heimbach, Stefanie [> >] Chouraki, Vincent [> >] Kuzma, Amanda B. [> >] Sleegers, Kristel [> >] Vronskaya, Maria [> >] Ruiz, Agustin [> >] Graham, Robert R. [> >] Olaso, Robert [> >] Hoffmann, Per [> >] Grove, Megan L. [> >] Vardarajan, Badri N. [> >] Hiltunen, Mikko [> >] Nothen, Markus M. [> >] White, Charles C. [> >] Hamilton-Nelson, Kara L. [> >] Epelbaum, Jacques [> >] Maier, Wolfgang [> >] Choi, Seung-Hoan [> >] Beecham, Gary W. [> >] Dulary, Cecile [> >] Herms, Stefan [> >] Smith, Albert V. [> >] Funk, Cory C. [> >] Derbois, Celine [> >] Forstner, Andreas J. [> >] Ahmad, Shahzad [> >] Li, Hongdong [> >] Bacq, Delphine [> >] Harold, Denise [> >] Satizabal, Claudia L. [> >] Valladares, Otto [> >] Squassina, Alessio [> >] Thomas, Rhodri [> >] Brody, Jennifer A. [> >] Qu, Liming [> >] Sanchez-Juan, Pascual [> >] Morgan, Taniesha [> >] Wolters, Frank J. [> >] Zhao, Yi [> >] Garcia, Florentino Sanchez [> >] Denning, Nicola [> >] Fornage, Myriam [> >] Malamon, John [> >] Naranjo, Maria Candida Deniz [> >] Majounie, Elisa [> >] Mosley, Thomas H. [> >] Dombroski, Beth [> >] Wallon, David [> >] Lupton, Michelle K. [> >] Dupuis, Josee [> >] Whitehead, Patrice [> >] Fratiglioni, Laura [> >] Medway, Christopher [> >] Jian, Xueqiu [> >] Mukherjee, Shubhabrata [> >] Keller, Lina [> >] Brown, Kristelle [> >] Lin, Honghuang [> >] Cantwell, Laura B. [> >] Panza, Francesco [> >] McGuinness, Bernadette [> >] Moreno-Grau, Sonia [> >] Burgess, Jeremy D. [> >] Solfrizzi, Vincenzo [> >] Proitsi, Petra [> >] Adams, Hieab H. [> >] Allen, Mariet [> >] Seripa, Davide [> >] Pastor, Pau [> >] Cupples, L. Adrienne [> >] Price, Nathan D. [> >] Hannequin, Didier [> >] Frank-Garcia, Ana [> >] Levy, Daniel [> >] Chakrabarty, Paramita [> >] Caffarra, Paolo [> >] Giegling, Ina [> >] Beiser, Alexa S. [> >] Giedraitis, Vilmantas [> >] Hampel, Harald [> >] Garcia, Melissa E. [> >] Wang, Xue [> >] Lannfelt, Lars [> >] Mecocci, Patrizia [> >] Eiriksdottir, Gudny [> >] Crane, Paul K. [> >] Pasquier, Florence [> >] Boccardi, Virginia [> >] Henandez, Isabel [> >] Barber, Robert C. [> >] Scherer, Martin [> >] Tarraga, Lluis [> >] Adams, Perrie M. [> >] Leber, Markus [> >] Chen, Yuning [> >] Albert, Marilyn S. [> >] Riedel-Heller, Steffi [> >] Emilsson, Valur [> >] Beekly, Duane [> >] Braae, Anne [> >] Schmidt, Reinhold [> >] Blacker, Deborah [> >] Masullo, Carlo [> >] Schmidt, Helena [> >] Doody, Rachelle S. [> >] Spalletta, Gianfranco [> >] Jr, W. T. Longstreth [> >] Fairchild, Thomas J. [> >] Bossu, Paola [> >] Lopez, Oscar L. [> >] Frosch, Matthew P. [> >] Sacchinelli, Eleonora [> >] Ghetti, Bernardino [> >] Yang, Qiong [> >] Huebinger, Ryan M. [> >] Jessen, Frank [> >] Li, Shuo [> >] Kamboh, M. Ilyas [> >] Morris, John [> >] Sotolongo-Grau, Oscar [> >] Katz, Mindy J. [> >] Corcoran, Chris [> >] Dunstan, Melanie [> >] Braddel, Amy [> >] Thomas, Charlene [> >] Meggy, Alun [> >] Marshall, Rachel [> >] Gerrish, Amy [> >] Chapman, Jade [> >] Aguilar, Miquel [> >] Taylor, Sarah [> >] Hill, Matt [> >] Fairen, Monica Diez [> >] Hodges, Angela [> >] Vellas, Bruno [> >] Soininen, Hilkka [> >] Kloszewska, Iwona [> >] Daniilidou, Makrina [> >] Uphill, James [> >] Patel, Yogen [> >] Hughes, Joseph T. [> >] Lord, Jenny [> >] Turton, James [> >] Hartmann, Annette M. [> >] Cecchetti, Roberta [> >] Fenoglio, Chiara [> >] Serpente, Maria [> >] Arcaro, Marina [> >] Caltagirone, Carlo [> >] Orfei, Maria Donata [> >] Ciaramella, Antonio [> >] Pichler, Sabrina [> >] Mayhaus, Manuel [> >] Gu, Wei [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >] Lleo, Alberto [> >] Fortea, Juan [> >] Blesa, Rafael [> >] Barber, Imelda S. [> >] Brookes, Keeley [> >] Cupidi, Chiara [> >] Maletta, Raffaele Giovanni [> >] Carrell, David [> >] Sorbi, Sandro [> >] Moebus, Susanne [> >] Urbano, Maria [> >] Pilotto, Alberto [> >] Kornhuber, Johannes [> >] Bosco, Paolo [> >] Todd, Stephen [> >] Craig, David [> >] Johnston, Janet [> >] Gill, Michael [> >] Lawlor, Brian [> >] Lynch, Aoibhinn [> >] Fox, Nick C. [> >] Hardy, John [> >] Consortium, A. R. U. K. [> >] Albin, Roger L. [> >] Apostolova, Liana G. [> >] Arnold, Steven E. [> >] Asthana, Sanjay [> >] Atwood, Craig S. [> >] Baldwin, Clinton T. [> >] Barnes, Lisa L. [> >] Barral, Sandra [> >] Beach, Thomas G. [> >] Becker, James T. [> >] Bigio, Eileen H. [> >] Bird, Thomas D. [> >] Boeve, Bradley F. [> >] Bowen, James D. [> >] Boxer, Adam [> >] Burke, James R. [> >] Burns, Jeffrey M. [> >] Buxbaum, Joseph D. [> >] Cairns, Nigel J. [> >] Cao, Chuanhai [> >] Carlson, Chris S. [> >] Carlsson, Cynthia M. [> >] Carney, Regina M. [> >] Carrasquillo, Minerva M. [> >] Carroll, Steven L. [> >] Diaz, Carolina Ceballos [> >] Chui, Helena C. [> >] Clark, David G. [> >] Cribbs, David H. [> >] Crocco, Elizabeth A. [> >] DeCarli, Charles [> >] Dick, Malcolm [> >] Duara, Ranjan [> >] Evans, Denis A. [> >] Faber, Kelley M. [> >] Fallon, Kenneth B. [> >] Fardo, David W. [> >] Farlow, Martin R. [> >] Ferris, Steven [> >] Foroud, Tatiana M. [> >] Galasko, Douglas R. [> >] Gearing, Marla [> >] Geschwind, Daniel H. [> >] Gilbert, John R. [> >] Graff-Radford, Neill R. [> >] Green, Robert C. [> >] Growdon, John H. [> >] Hamilton, Ronald L. [> >] Harrell, Lindy E. [> >] Honig, Lawrence S. [> >] Huentelman, Matthew J. [> >] Hulette, Christine M. [> >] Hyman, Bradley T. [> >] Jarvik, Gail P. [> >] Abner, Erin [> >] Jin, Lee-Way [> >] Jun, Gyungah [> >] Karydas, Anna [> >] Kaye, Jeffrey A. [> >] Kim, Ronald [> >] Kowall, Neil W. [> >] Kramer, Joel H. [> >] LaFerla, Frank M. [> >] Lah, James J. [> >] Leverenz, James B. [> >] Levey, Allan I. [> >] Li, Ge [> >] Lieberman, Andrew P. [> >] Lunetta, Kathryn L. [> >] Lyketsos, Constantine G. [> >] Marson, Daniel C. [> >] Martiniuk, Frank [> >] Mash, Deborah C. [> >] Masliah, Eliezer [> >] McCormick, Wayne C. [> >] McCurry, Susan M. [> >] McDavid, Andrew N. [> >] McKee, Ann C. [> >] Mesulam, Marsel [> >] Miller, Bruce L. [> >] Miller, Carol A. [> >] Miller, Joshua W. [> >] Morris, John C. [> >] Murrell, Jill R. [> >] Myers, Amanda J. [> >] O'Bryant, Sid [> >] Olichney, John M. [> >] Pankratz, Vernon S. [> >] Parisi, Joseph E. [> >] Paulson, Henry L. [> >] Perry, William [> >] Peskind, Elaine [> >] Pierce, Aimee [> >] Poon, Wayne W. [> >] Potter, Huntington [> >] Quinn, Joseph F. [> >] Raj, Ashok [> >] Raskind, Murray [> >] Reisberg, Barry [> >] Reitz, Christiane [> >] Ringman, John M. [> >] Roberson, Erik D. [> >] Rogaeva, Ekaterina [> >] Rosen, Howard J. [> >] Rosenberg, Roger N. [> >] Sager, Mark A. [> >] Saykin, Andrew J. [> >] Schneider, Julie A. [> >] Schneider, Lon S. [> >] Seeley, William W. [> >] Smith, Amanda G. [> >] Sonnen, Joshua A. [> >] Spina, Salvatore [> >] Stern, Robert A. [> >] Swerdlow, Russell H. [> >] Tanzi, Rudolph E. [> >] Thornton-Wells, Tricia A. [> >] Trojanowski, John Q. [> >] Troncoso, Juan C. [> >] Van Deerlin, Vivianna M. [> >] Van Eldik, Linda J. [> >] Vinters, Harry V. [> >] Vonsattel, Jean Paul [> >] Weintraub, Sandra [> >] Welsh-Bohmer, Kathleen A. [> >] Wilhelmsen, Kirk C. [> >] Williamson, Jennifer [> >] Wingo, Thomas S. [> >] Woltjer, Randall L. [> >] Wright, Clinton B. [> >] Yu, Chang-En [> >] Yu, Lei [> >] Garzia, Fabienne [> >] Golamaully, Feroze [> >] Septier, Gislain [> >] Engelborghs, Sebastien [> >] Vandenberghe, Rik [> >] De Deyn, Peter P. [> >] Fernadez, Carmen Munoz [> >] Benito, Yoland Aladro [> >] Thonberg, Hakan [> >] Forsell, Charlotte [> >] Lilius, Lena [> >] Kinhult-Stahlbom, Anne [> >] Kilander, Lena [> >] Brundin, Rosemarie [> >] Concari, Letizia [> >] Helisalmi, Seppo [> >] Koivisto, Anne Maria [> >] Haapasalo, Annakaisa [> >] Dermecourt, Vincent [> >] Fievet, Nathalie [> >] Hanon, Olivier [> >] Dufouil, Carole [> >] Brice, Alexis [> >] Ritchie, Karen [> >] Dubois, Bruno [> >] Himali, Jayanadra J. [> >] Keene, C. Dirk [> >] Tschanz, Joann [> >] Fitzpatrick, Annette L. [> >] Kukull, Walter A. [> >] Norton, Maria [> >] Aspelund, Thor [> >] Larson, Eric B. [> >] Munger, Ron [> >] Rotter, Jerome I. [> >] Lipton, Richard B. [> >] Bullido, Maria J. [> >] Hofman, Albert [> >] Montine, Thomas J. [> >] Coto, Eliecer [> >] Boerwinkle, Eric [> >] Petersen, Ronald C. [> >] Alvarez, Victoria [> >] Rivadeneira, Fernando [> >] Reiman, Eric M. [> >] Gallo, Maura [> >] O'Donnell, Christopher J. [> >] Reisch, Joan S. [> >] Bruni, Amalia Cecilia [> >] Royall, Donald R. [> >] Dichgans, Martin [> >] Sano, Mary [> >] Galimberti, Daniela [> >] St George-Hyslop, Peter [> >] Scarpini, Elio [> >] Tsuang, Debby W. [> >] Mancuso, Michelangelo [> >] Bonuccelli, Ubaldo [> >] Winslow, Ashley R. [> >] Daniele, Antonio [> >] Wu, Chuang-Kuo [> >] GERAD/PERADES, Charge Adgc Eadi [> >] Peters, Oliver [> >] Nacmias, Benedetta [> >] Riemenschneider, Matthias [> >] Heun, Reinhard [> >] Brayne, Carol [> >] Rubinsztein, David C. [> >] Bras, Jose [> >] Guerreiro, Rita [> >] Al-Chalabi, Ammar [> >] Shaw, Christopher E. [> >] Collinge, John [> >] Mann, David [> >] Tsolaki, Magda [> >] Clarimon, Jordi [> >] Sussams, Rebecca [> >] Lovestone, Simon [> >] O'Donovan, Michael C. [> >] Owen, Michael J. [> >] Behrens, Timothy W. [> >] Mead, Simon [> >] Goate, Alison M. [> >] Uitterlinden, Andre G. [> >] Holmes, Clive [> >] Cruchaga, Carlos [> >] Ingelsson, Martin [> >] Bennett, David A. [> >] Powell, John [> >] Golde, Todd E. [> >] Graff, Caroline [> >] De Jager, Philip L. [> >] Morgan, Kevin [> >] Ertekin-Taner, Nilufer [> >] Combarros, Onofre [> >] Psaty, Bruce M. [> >] Passmore, Peter [> >] Younkin, Steven G. [> >] Berr, Claudine [> >] Gudnason, Vilmundur [> >] Rujescu, Dan [> >] Dickson, Dennis W. [> >] Dartigues, Jean-Francois [> >] DeStefano, Anita L. [> >] Ortega-Cubero, Sara [> >] Hakonarson, Hakon [> >] Campion, Dominique [> >] Boada, Merce [> >] Kauwe, John Keoni [> >] Farrer, Lindsay A. [> >] Van Broeckhoven, Christine [> >] Ikram, M. Arfan [> >] Jones, Lesley [> >] Haines, Jonathan L. [> >] Tzourio, Christophe [> >] Launer, Lenore J. [> >] Escott-Price, Valentina [> >] Mayeux, Richard [> >] Deleuze, Jean-Francois [> >] Amin, Najaf [> >] Holmans, Peter A. [> >] Pericak-Vance, Margaret A. [> >] Amouyel, Philippe [> >] van Duijn, Cornelia M. [> >] Ramirez, Alfredo [> >] Wang, Li-San [> >] Lambert, Jean-Charles [> >] Seshadri, Sudha [> >] Williams, Julie [> >] Schellenberg, Gerard D. [> >] Publication date : 2017 Journal title : Nature Genetics Publisher : Nature Publishing Group Volume : 49 Pages : 1373-1384 Peer reviewed : Yes (verified by ORBilu ) Audience : International ISSN : 1061-4036 e-ISSN : 1546-1718 City : New York Country : NY Research centres : Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) Target : Researchers ; Professionals Permalink : http://hdl.handle.net/10993/32071 DOI : 10.1038/ng.3916 Other URL : http://dx.doi.org/10.1038/ng.3916 Mentions required by the publisher for OA : Nature Publishing Group does not offer licenses to reuse its full PDF content online. You may reuse an abstract free of charge or link to the Nature Publishing Group directly from your website. 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Commentary : Letter 
