Abstract :
[en] MOTIVATION:
Flux balance analysis, and its variants, are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.
RESULTS:
DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.
AVAILABILITY:
The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl.
Disciplines :
Biochemistry, biophysics & molecular biology
Engineering, computing & technology: Multidisciplinary, general & others
Funders :
National Centre of Excellence in Research (NCER) on Parkinson’s disease
Luxembourg National Research Fund (FNR) ATTRACT program grant (FNR/A12/01)
U.S. Department of Energy, Offices of Advanced Scientific Computing Research and the Biological and Environmental Research as part of the Scientific Discovery Through Advanced Computing program, grant no. DE-SC0010429
Scopus citations®
without self-citations
16
