Article (Scientific journals)
ReconMap: An interactive visualisation of human metabolism
Noronha, Alberto; Danielsdóttir, Anna Dröfn; Jóhannsson, Freyr et al.
2016In Bioinformatics
Peer reviewed
 

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Abstract :
[en] A genome-scale reconstruction of human metabolism, Recon 2, is available but no interface exists to interactively visualise its content integrated with omics data and simulation results. We manually drew a comprehensive map, ReconMap 2.0, that is consistent with the content of Recon 2. We present it within a web interface that allows content query, visualization of custom datasets and submission of feedback to manual curators. ReconMap can be accessed via http://vmh.uni.lu, with network export in a Systems Biology Graphical Notation compliant format. A Constraint-Based Reconstruction and Analysis (COBRA) Toolbox extension to interact with ReconMap is available via https://github.com/opencobra/cobratoolbox.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Noronha, Alberto ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Danielsdóttir, Anna Dröfn;  University of Iceland > Center for Systems Biology
Jóhannsson, Freyr;  Universuty of Iceland > Center for Systems Biology
Jónsdóttir, Soffia;  University of Iceland > Center for Systems Biology
Jarlsson, Sindri;  University of Iceland > Center for Systems Biology
Gunnarsson, Jón Pétur;  University of Iceland > Center for Systems Biology
Brynjólfsson, Sigurður;  University of Iceland > Center for Systems Biology
Gawron, Piotr ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Schneider, Reinhard ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Thiele, Ines ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Fleming, Ronan MT ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
External co-authors :
yes
Language :
English
Title :
ReconMap: An interactive visualisation of human metabolism
Publication date :
2016
Journal title :
Bioinformatics
ISSN :
1367-4803
eISSN :
1460-2059
Publisher :
Oxford University Press - Journals Department, Oxford, United Kingdom
Peer reviewed :
Peer reviewed
Focus Area :
Systems Biomedicine
Available on ORBilu :
since 23 July 2016

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