[en] A genome-scale reconstruction of human metabolism, Recon 2, is available but no interface exists to interactively visualise its content integrated with omics data and simulation results. We manually drew a comprehensive map, ReconMap 2.0, that is consistent with the content of Recon 2. We present it within a web interface that allows content query, visualization of custom datasets and submission of feedback to manual curators. ReconMap can be accessed via http://vmh.uni.lu, with network export in a Systems Biology Graphical Notation compliant format. A Constraint-Based Reconstruction and Analysis (COBRA) Toolbox extension to interact with ReconMap is available via https://github.com/opencobra/cobratoolbox.
Disciplines :
Biochimie, biophysique & biologie moléculaire
Auteur, co-auteur :
NORONHA, Alberto ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Danielsdóttir, Anna Dröfn; University of Iceland > Center for Systems Biology
Jóhannsson, Freyr; Universuty of Iceland > Center for Systems Biology
Jónsdóttir, Soffia; University of Iceland > Center for Systems Biology
Jarlsson, Sindri; University of Iceland > Center for Systems Biology
Gunnarsson, Jón Pétur; University of Iceland > Center for Systems Biology
Brynjólfsson, Sigurður; University of Iceland > Center for Systems Biology
GAWRON, Piotr ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
SCHNEIDER, Reinhard ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
THIELE, Ines ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
FLEMING, Ronan MT ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Co-auteurs externes :
yes
Langue du document :
Anglais
Titre :
ReconMap: An interactive visualisation of human metabolism
Date de publication/diffusion :
2016
Titre du périodique :
Bioinformatics
ISSN :
1367-4803
eISSN :
1460-2059
Maison d'édition :
Oxford University Press - Journals Department, Oxford, Royaume-Uni
