[en] Systems biology ; Metabolic networks ; Transcriptional regulatory networks ; Constraint-based modeling ; Probabilistic regulation of metabolism ; Microarray data
[en] The integration of transcriptional regulatory and metabolic networks is a crucial step in the process of predicting metabolic behaviors that emerge from either genetic or environmental changes. Here, we present a guide to PROM (probabilistic regulation of metabolism), an automated method for the construction and simulation of integrated metabolic and transcriptional regulatory networks that enables large-scale phenotypic predictions for a wide range of model organisms.
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group)
[University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
