Reference : A roadmap for interpreting (13)C metabolite labeling patterns from cells.
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/10993/27269
A roadmap for interpreting (13)C metabolite labeling patterns from cells.
English
Buescher, Joerg M. [> >]
Antoniewicz, Maciek R. [> >]
Boros, Laszlo G. [> >]
Burgess, Shawn C. [> >]
Brunengraber, Henri [> >]
Clish, Clary B. [> >]
DeBerardinis, Ralph J. [> >]
Feron, Olivier [> >]
Frezza, Christian [> >]
Ghesquiere, Bart [> >]
Gottlieb, Eyal [> >]
Hiller, Karsten mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
Jones, Russell G. [> >]
Kamphorst, Jurre J. [> >]
Kibbey, Richard G. [> >]
Kimmelman, Alec C. [> >]
Locasale, Jason W. [> >]
Lunt, Sophia Y. [> >]
Maddocks, Oliver D. K. [> >]
Malloy, Craig [> >]
Metallo, Christian M. [> >]
Meuillet, Emmanuelle J. [> >]
Munger, Joshua [> >]
Noh, Katharina [> >]
Rabinowitz, Joshua D. [> >]
Ralser, Markus [> >]
Sauer, Uwe [> >]
Stephanopoulos, Gregory [> >]
St-Pierre, Julie [> >]
Tennant, Daniel A. [> >]
Wittmann, Christoph [> >]
Vander Heiden, Matthew G. [> >]
Vazquez, Alexei [> >]
Vousden, Karen [> >]
Young, Jamey D. [> >]
Zamboni, Nicola [> >]
Fendt, Sarah-Maria [> >]
2015
Current opinion in biotechnology
34
189-201
Yes (verified by ORBilu)
0958-1669
1879-0429
England
[en] Animals ; Carbon Isotopes/metabolism ; Cell Survival ; Humans ; Isotope Labeling/methods ; Metabolic Networks and Pathways
[en] Measuring intracellular metabolism has increasingly led to important insights in biomedical research. (13)C tracer analysis, although less information-rich than quantitative (13)C flux analysis that requires computational data integration, has been established as a time-efficient method to unravel relative pathway activities, qualitative changes in pathway contributions, and nutrient contributions. Here, we review selected key issues in interpreting (13)C metabolite labeling patterns, with the goal of drawing accurate conclusions from steady state and dynamic stable isotopic tracer experiments.
http://hdl.handle.net/10993/27269
Copyright (c) 2015 Elsevier Ltd. All rights reserved.

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