[en] Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.
Research center :
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group)
Disciplines :
Genetics & genetic processes
Author, co-author :
Schughart, Klaus
Libert, Claude
Kas, Martien J.
Andreux, Penelope
Aransay, Ana Maria
Auwerx, Johan
Balling, Rudi ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
