| Reference : EXPLORING THE MYCOPLASMA-CAPRICOLUM GENOME - A MINIMAL CELL REVEALS ITS PHYSIOLOGY |
| Scientific journals : Article | |||
| Life sciences : Biochemistry, biophysics & molecular biology | |||
| http://hdl.handle.net/10993/26558 | |||
| EXPLORING THE MYCOPLASMA-CAPRICOLUM GENOME - A MINIMAL CELL REVEALS ITS PHYSIOLOGY | |
| English | |
| BORK, P. [> >] | |
| OUZOUNIS, C. [> >] | |
| CASARI, G. [> >] | |
Schneider, Reinhard  [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >] | |
| SANDER, C. [> >] | |
| DOLAN, M. [> >] | |
| GILBERT, W. [> >] | |
| GILLEVET, P. M. [> >] | |
| 1995 | |
| Molecular Microbiology | |
| Blackwell Publishing | |
| 16 | |
| 5 | |
| 955-967 | |
| Yes (verified by ORBilu) | |
| 0950-382X | |
| 1365-2958 | |
| Oxford | |
| United Kingdom | |
| [en] We report on the analysis of 214 kb of the parasitic eubacterium Mycoplasma capricolum sequenced by genomic walking techniques. The 287 putative proteins detected to date represent about half of the estimated total number of 500 predicted for this organism. A large fraction of these (75%) can be assigned a likely function as a result of similarity searches. Several important features of the functional organization of this small genome are already apparent. Among these are (i) the expected relatively large number of enzymes involved in metabolic transport and activation, for efficient use of host cell nutrients; (ii) the presence of anabolic enzymes; (iii) the unexpected diversity of enzymes involved in DNA replication and repair; and (iv) a sizeable number of orthologues (82 so far) in Escherichia coil. This survey is beginning to provide a detailed view of how M. capricolum manages to maintain essential cellular processes with a genome much smaller than that of its bacterial relatives. | |
| http://hdl.handle.net/10993/26558 |
There is no file associated with this reference.
All documents in ORBilu are protected by a user license.
