Article (Scientific journals)
Early-stage folding in proteins (in silico) sequence-to-structure relation
Brylinski, Michal; Konieczny, Leszek; Czerwonko, Patryk et al.
2005In Journal of Biomedicine & Biotechnology, 2005 (2), p. 65-79
Peer reviewed
 

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Abstract :
[en] A sequence-to-structure library has been created based on the complete PDB database. The tetrapeptide was selected as a unit representing a well-defined structural motif. Seven structural forms were introduced for structure classification. The early-stage folding conformations were used as the objects for structure analysis and classification. The degree of determinability was estimated for the sequence-to-structure and structure-to-sequence relations. Probability calculus and informational entropy were applied for quantitative estimation of the mutual relation between them. The structural motifs representing different forms of loops and bends were found to favor particular sequences in structure-to-sequence analysis.
Disciplines :
Biochemistry, biophysics & molecular biology
Identifiers :
UNILU:UL-ARTICLE-2012-586
Author, co-author :
Brylinski, Michal
Konieczny, Leszek
Czerwonko, Patryk
Jurkowski, Wiktor ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Roterman, Irena
External co-authors :
yes
Language :
English
Title :
Early-stage folding in proteins (in silico) sequence-to-structure relation
Publication date :
2005
Journal title :
Journal of Biomedicine & Biotechnology
ISSN :
1110-7243
eISSN :
1110-7251
Publisher :
Hindawi Publishing Corporation
Volume :
2005
Issue :
2
Pages :
65-79
Peer reviewed :
Peer reviewed
Available on ORBilu :
since 08 April 2016

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