4th International Conference on Complex Systems and Applications
from 23-06-2014 to 26-06-2014
Normandie University
Le Havre
France
[en] Nonlinear system ; ODE model ; reactive oxygen species
[en] Reactive oxygen species (ROS) play important role in the functioning of any cell and especially in the lifecycle of mitochondria. Since the action of ROS can be both positive and negative then the remarkable role can be played by ROS regulation system. We constructed three different ODE based kinetic models of different complexity for the ROS management system and shown the difference in the dynamics of these systems under different conditions. Using results of numerical simulation we showed that extraction of some subsystems can make the model more unstable. We also introduced the objective function for comparison of the models with structure of different complexity
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group)