Article (Scientific journals)
Effective thalamic deep brain stimulation for neuropathic tremor in a patient with severe demyelinating neuropathy.
Breit, S.; Wachter, T.; Schols, L. et al.
2009In Journal of Neurology, Neurosurgery and Psychiatry, 80 (2), p. 235-6
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Keywords :
Aged; Deep Brain Stimulation/methods; Demyelinating Diseases/complications; Electrodes, Implanted; Humans; Hypertrophy/complications/pathology; Male; Myelin Sheath/pathology; Peripheral Nervous System Diseases/complications; Thalamus/physiology; Tremor/etiology/therapy
Abstract :
[en] Postural and action tremor in peripheral neuropathy is characteristic of Roussy-Levy syndrome. A patient with a severe demyelinating neuropathy and disabling neuropathic tremor successfully treated by deep brain stimulation (DBS) is reported. Disease onset was at age 63 years with sensory symptoms and slight action tremor. Within the following 9 years a severe, drug resistant, postural and action tremor developed rendering the patient unable to feed himself. At age 72 years the patient was treated by bilateral DBS of the ventral intermediate thalamic nucleus, with a useful 30% reduction in tremor. The clinical benefit of the stimulation remained stable over a 1 year postoperative observation period.
Research center :
- Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group)
Disciplines :
Genetics & genetic processes
Author, co-author :
Breit, S.
Wachter, T.
Schols, L.
Gasser, T.
Nagele, T.
Freudenstein, D.
KRÜGER, Rejko ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit
Language :
English
Title :
Effective thalamic deep brain stimulation for neuropathic tremor in a patient with severe demyelinating neuropathy.
Publication date :
2009
Journal title :
Journal of Neurology, Neurosurgery and Psychiatry
ISSN :
1468-330X
Publisher :
BMJ Publishing Group, United Kingdom
Volume :
80
Issue :
2
Pages :
235-6
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 28 June 2014

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