Reference : Effective thalamic deep brain stimulation for neuropathic tremor in a patient with se...
Scientific journals : Article
Life sciences : Genetics & genetic processes
Effective thalamic deep brain stimulation for neuropathic tremor in a patient with severe demyelinating neuropathy.
Breit, S. [> >]
Wachter, T. [> >]
Schols, L. [> >]
Gasser, T. [> >]
Nagele, T. [> >]
Freudenstein, D. [> >]
Krüger, Rejko mailto [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit]
Journal of neurology, neurosurgery, and psychiatry
Yes (verified by ORBilu)
[en] Aged ; Deep Brain Stimulation/methods ; Demyelinating Diseases/complications ; Electrodes, Implanted ; Humans ; Hypertrophy/complications/pathology ; Male ; Myelin Sheath/pathology ; Peripheral Nervous System Diseases/complications ; Thalamus/physiology ; Tremor/etiology/therapy
[en] Postural and action tremor in peripheral neuropathy is characteristic of Roussy-Levy syndrome. A patient with a severe demyelinating neuropathy and disabling neuropathic tremor successfully treated by deep brain stimulation (DBS) is reported. Disease onset was at age 63 years with sensory symptoms and slight action tremor. Within the following 9 years a severe, drug resistant, postural and action tremor developed rendering the patient unable to feed himself. At age 72 years the patient was treated by bilateral DBS of the ventral intermediate thalamic nucleus, with a useful 30% reduction in tremor. The clinical benefit of the stimulation remained stable over a 1 year postoperative observation period.
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group)

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