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Cloning and expression analysis of a novel mesodermally expressed cadherin.
Hoffmann, I.; Balling, Rudi
1995In Developmental Biology, 169 (1), p. 337-46
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Keywords :
Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cadherins/biosynthesis/genetics; Cloning, Molecular; DNA-Binding Proteins; Ectoderm/metabolism; Embryo, Mammalian/anatomy & histology; In Situ Hybridization; Mesoderm/metabolism; Mice; Molecular Sequence Data; Muscle Proteins/biosynthesis/genetics; Myogenic Regulatory Factor 5; Nervous System/embryology/metabolism; RNA, Messenger/analysis; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Trans-Activators
Abstract :
[en] Cadherins are calcium-dependent cell adhesion molecules which show developmental and tissue-specific expression. Here we report the cloning of a mouse cadherin which is predominantly expressed in tissues of mesodermal origin. In contrast to other cadherins, cadherin-11 expression is largely restricted to mesenchymal tissues surrounding various organs but is not found in epithelia. Sequence analysis suggests that this cadherin is the mouse homologue of the previously reported human cadherin-11 and is a member of a cadherin subfamily, which is evolutionarily distinct from other cadherin subfamilies identified so far.
Disciplines :
Genetics & genetic processes
Author, co-author :
Hoffmann, I.
Balling, Rudi 
Language :
English
Title :
Cloning and expression analysis of a novel mesodermally expressed cadherin.
Publication date :
1995
Journal title :
Developmental Biology
ISSN :
1095-564X
Publisher :
Elsevier, Atlanta, United States - Florida
Volume :
169
Issue :
1
Pages :
337-46
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 10 May 2013

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