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Article (Scientific journals)
Oxidative and conjugative metabolism of diethylstilbestrol by rabbit preimplantation embryos.
BALLING, Rudi; Haaf, H.; Maydl, R. et al.
1985 • In Developmental Biology, 109 (2), p. 370-4
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https://hdl.handle.net/10993/1252
DOI
10.1016/0012-1606(85)90462-2
PubMed
3922826
 

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Keywords :
Animals; Biotransformation; Blastocyst/metabolism; Diethylstilbestrol/analogs & derivatives/metabolism; Gestational Age; Glucuronosyltransferase/metabolism; Oxygenases/metabolism; Rabbits; Sulfurtransferases/metabolism
Abstract :
[en] Five- and six-day-old rabbit preimplantation embryos were found to be capable of metabolizing [3H]diethylstilbestrol (DES) in vitro. Based on the analysis of the metabolites formed during a 24-hr incubation period we conclude that these early stage embryos do have active monooxygenase and conjugative activity. The monooxygenase seems to be specific to this early stage of embryonic development.
Disciplines :
Genetics & genetic processes
Author, co-author :
BALLING, Rudi 
Haaf, H.
Maydl, R.
Metzler, M.
Beier, H. M.
Language :
English
Title :
Oxidative and conjugative metabolism of diethylstilbestrol by rabbit preimplantation embryos.
Publication date :
1985
Journal title :
Developmental Biology
ISSN :
0012-1606
eISSN :
1095-564X
Publisher :
Elsevier, Atlanta, United States - Florida
Volume :
109
Issue :
2
Pages :
370-4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 10 May 2013

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