Contribution to collective works (Parts of books)
Functional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology
Ballereau, S.; Glaab, Enrico; Kolodkin, Alexey et al.
2013In Prokop, Ales; Csukás, Bela (Eds.) Systems Biology: Integrative Biology and Simulation Tools
Peer reviewed
 

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Keywords :
Emergence; Holistic; Bottom-up; Top-down; Middle-out; Interactions; Data integration; Mathematical model; Functional genomics
Abstract :
[en] This chapter introduces systems biology, its context, aims, concepts and strategies. It then describes approaches and methods used for collection of high-dimensional structural and functional genomics data, including epigenomics, transcriptomics, proteomics, metabolomics and lipidomics, and how recent technological advances in these fields have moved the bottleneck from data production to data analysis and bioinformatics. Finally, the most advanced mathematical and computational methods used for clustering, feature selection, prediction analysis, text mining and pathway analysis in functional genomics and systems biology are reviewed and discussed in the context of use cases.
Research center :
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group)
Disciplines :
Human health sciences: Multidisciplinary, general & others
Computer science
Biochemistry, biophysics & molecular biology
Identifiers :
UNILU:UL-CHAPTER-2013-013
Author, co-author :
Ballereau, S.
Glaab, Enrico  ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Kolodkin, Alexey ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Chaiboonchoe, A.
Biryukov, Maria ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Vlassis, Nikos ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Ahmed, H.
Pellet, J.
Baliga, N.
Hood, Leroy 
Schneider, Reinhard ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Balling, Rudi ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Auffray, C.
More authors (3 more) Less
External co-authors :
yes
Language :
English
Title :
Functional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology
Publication date :
2013
Main work title :
Systems Biology: Integrative Biology and Simulation Tools
Editor :
Prokop, Ales
Csukás, Bela
Publisher :
Springer
Peer reviewed :
Peer reviewed
Commentary :
in press
Available on ORBilu :
since 10 May 2013

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