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CRUCIANI Gérald

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Scientific Central Services > Disease Modelling and Screening Platform (DMSP Platform)

Main Referenced Co-authors
KRÜGER, Rejko  (6)
ANTONY, Paul  (4)
MASSART, François  (4)
DORDING, Claire  (3)
SCHWAMBORN, Jens Christian  (3)
Main Referenced Keywords
iPSC (3); A30P (2); SNCA (2); alpha-synuclein (1); CRISPR-Cas9 (1);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (3)
Genetics & genetic processes (2)
Neurology (1)
Human health sciences: Multidisciplinary, general & others (1)
Biotechnology (1)

Publications (total 6)

The most downloaded
62 downloads
Larsen, S., Hanss, Z., Cruciani, G., Massart, F., Barbuti, P., Mellick, G., & Krüger, R. (2020). Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35. Stem Cell Research. doi:10.1016/j.scr.2020.101776 https://hdl.handle.net/10993/43432

The most cited

29 citations (Scopus®)

Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L., Su, J., Arias-Fuenzalida, Walter, J., Gomez Giro, G., Monzel, A., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., ... Schwamborn, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 https://hdl.handle.net/10993/48390

Barbuti, P. A., Ohnmacht, J., Santos, B. F., Antony, P., Massart, F., Cruciani, G., Dording, C. M., Pavelka, L., Casadei, N., Kwon, Y.-J., & Krüger, R. (09 November 2021). Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports, 11, 21946. doi:10.1038/s41598-021-01505-x
Peer Reviewed verified by ORBi

Boussaad, I., Cruciani, G., Bolognin, S., Antony, P., Dording, C., Kwon, Y.-J., Heuting, P., Fava, E., Schwamborn, J. C., & Krüger, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3
Peer Reviewed verified by ORBi

Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L., Su, J., Arias-Fuenzalida, Walter, J., Gomez Giro, G., Monzel, A., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., ... Schwamborn, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810
Peer Reviewed verified by ORBi

Barbuti, P., Santos, B., Dording, C., Cruciani, G., Massart, F., Hummel, A., & Krüger, R. (October 2020). Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA. Stem Cell Research, 48, 101951. doi:10.1016/j.scr.2020.101951
Peer Reviewed verified by ORBi

Larsen, S., Hanss, Z., Cruciani, G., Massart, F., Barbuti, P., Mellick, G., & Krüger, R. (2020). Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35. Stem Cell Research. doi:10.1016/j.scr.2020.101776
Peer Reviewed verified by ORBi

Barbuti, P., Antony, P., Rodrigues Santos, B., Massart, F., Cruciani, G., Dording, C., Arias, J., Schwamborn, J. C., & Krüger, R. (2020). Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson's Disease Point Mutation A30P. Cells, 9 (9). doi:10.3390/cells9092065
Peer Reviewed verified by ORBi

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