Profil

CRUCIANI Gérald

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Scientific Central Services > Disease Modelling and Screening Platform (DMSP Platform)

Main Referenced Co-authors
KRÜGER, Rejko  (6)
ANTONY, Paul  (4)
MASSART, François  (4)
DORDING, Claire  (3)
SCHWAMBORN, Jens Christian  (3)
Main Referenced Keywords
iPSC (3); A30P (2); SNCA (2); alpha-synuclein (1); CRISPR-Cas9 (1);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (3)
Genetics & genetic processes (2)
Neurology (1)
Human health sciences: Multidisciplinary, general & others (1)
Biotechnology (1)

Publications (total 6)

The most downloaded
76 downloads
LARSEN, S., HANSS, Z., CRUCIANI, G., MASSART, F., BARBUTI, P., Mellick, G., & KRÜGER, R. (2020). Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35. Stem Cell Research. doi:10.1016/j.scr.2020.101776 https://hdl.handle.net/10993/43432

The most cited

54 citations (OpenAlex)

JARAZO, J., BARMPA, K., Modamio, J., SARAIVA, C., SABATÉ SOLER, S., ROSETY, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., SMITS, L., Su, J., Arias-Fuenzalida, Walter, J., GOMEZ GIRO, G., Monzel, A., Qing, X., VITALI, A., CRUCIANI, G., BOUSSAAD, I., ... SCHWAMBORN, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810 https://hdl.handle.net/10993/48390

Barbuti, P. A., OHNMACHT, J., Santos, B. F., ANTONY, P., MASSART, F., CRUCIANI, G., Dording, C. M., PAVELKA, L., Casadei, N., KWON, Y.-J., & KRÜGER, R. (09 November 2021). Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports, 11, 21946. doi:10.1038/s41598-021-01505-x
Peer Reviewed verified by ORBi

BOUSSAAD, I., CRUCIANI, G., BOLOGNIN, S., ANTONY, P., DORDING, C., KWON, Y.-J., Heuting, P., Fava, E., SCHWAMBORN, J. C., & KRÜGER, R. (2021). Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening. Scientific Reports. doi:10.1038/s41598-021-81129-3
Peer Reviewed verified by ORBi

JARAZO, J., BARMPA, K., Modamio, J., SARAIVA, C., SABATÉ SOLER, S., ROSETY, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., SMITS, L., Su, J., Arias-Fuenzalida, Walter, J., GOMEZ GIRO, G., Monzel, A., Qing, X., VITALI, A., CRUCIANI, G., BOUSSAAD, I., ... SCHWAMBORN, J. C. (2021). Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment. Movement Disorders. doi:10.1002/mds.28810
Peer Reviewed verified by ORBi

Barbuti, P., Santos, B., DORDING, C., CRUCIANI, G., MASSART, F., Hummel, A., & KRÜGER, R. (October 2020). Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA. Stem Cell Research, 48, 101951. doi:10.1016/j.scr.2020.101951
Peer Reviewed verified by ORBi

LARSEN, S., HANSS, Z., CRUCIANI, G., MASSART, F., BARBUTI, P., Mellick, G., & KRÜGER, R. (2020). Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35. Stem Cell Research. doi:10.1016/j.scr.2020.101776
Peer Reviewed verified by ORBi

BARBUTI, P., ANTONY, P., RODRIGUES SANTOS, B., MASSART, F., CRUCIANI, G., DORDING, C., ARIAS, J., SCHWAMBORN, J. C., & KRÜGER, R. (2020). Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson's Disease Point Mutation A30P. Cells, 9 (9). doi:10.3390/cells9092065
Peer Reviewed verified by ORBi

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