  | KAYA, P., SCHAFFNER-RECKINGER, E., MANOHARAN, G. B., Vukic, V., Kiriazis, A., LEDDA, M., Burgos, M., PAVIC, K., GAIGNEAUX, A., GLAAB, E., & ABANKWA, D. (2023). An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58308. doi:10.1101/2023.08.23.554263 |
 | Steffen, C., Kaya, P., Schaffner-Reckinger, E., & Abankwa, D. (2023). Eliminating oncogenic RAS: back to the future at the drawing board. Biochemical Society Transactions. doi:10.1042/BST20221343  Peer Reviewed verified by ORBi |
 | KAYA, P., SCHAFFNER-RECKINGER, E., MANOHARAN, G. B., Saley, B., & ABANKWA, D. (18 October 2022). Novel High Affinity Inhibitors Of The K-Ras Trafficking Chaperone PDE6D [Paper presentation]. The Fourth RAS Initiative Symposium, Frederick, United States. Peer reviewed |
 | Cipriani, C., Pires Pacheco, M. I., Kishk, A., Wachich, M., Abankwa, D., Schaffner-Reckinger, E., & Sauter, T. (2022). Bruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability Assay. Pharmaceuticals (Basel, Switzerland), 15 (2). doi:10.3390/ph15020179 Peer reviewed |
 | Machado, R. A. C., Stojevski, D., de Landtsheer, S., Lucarelli, P., Baron, A., Sauter, T., & Schaffner-Reckinger, E. (22 February 2021). L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness. Cell Communication and Signaling, 19 (22), 1-22. doi:10.21203/rs.3.rs-276404/v1 Peer Reviewed verified by ORBi |
  | Schaffner-Reckinger, E., & Machado, R. A. C. (2020). The actin-bundling protein L-plastin—A double-edged sword: Beneficial for the immune response, maleficent in cancer. In INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY (Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, pp. 109-154). Amsterdam, Netherlands: Elsevier. doi:10.1016/bs.ircmb.2020.05.004 Peer reviewed |
 | Schenk, L. K., Möller-Kerutt, A., Klosowski, R., Wolters, D., Schaffner, E., Weide, T., Pavenstädt, H., & Vollenbröker, B. (2017). Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes. FASEB Journal. doi:10.1096/fj.201700142R Peer Reviewed verified by ORBi |
 | Sala, S., Catillon, M., Hadzic, E., Schaffner, E., Van Troys, M., & Ampe, C. (2017). The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions. PLoS ONE. doi:10.1371/journal.pone.0177879 Peer Reviewed verified by ORBi |
 | SALA, S., Van troys, M., Medves, S., Catillon, M., Timmerman, E., Staes, A., Schaffner, E., Gevaert, K., & Ampe, C. (05 April 2017). Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations. Journal of Proteome Research, doi: 10.1021/acs.jproteome.7b00034. doi:10.1021/acs.jproteome.7b00034 Peer Reviewed verified by ORBi |
 | Lommel, M., Trairatphisan, P., Gäbler, K., Laurini, C., Muller, A., Kaoma, T., Vallar, L., Sauter, T., & Schaffner, E. (2016). L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway. FASEB Journal. doi:10.1096/fj.15-276311 Peer Reviewed verified by ORBi |
 | Hadzic, E., Catillon, M., Halavatyi, A., Medves, S., Van Troys, M., Moes, M., Baird, M. A., Davidson, M. W., Schaffner, E., Ampe, C., & Friederich, E. (2015). Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption. PLoS ONE. doi:10.1371/journal.pone.0140511 Peer Reviewed verified by ORBi |
 | Lee, W. H., Schaffner, E., Tsoukatos, D. C., Aylward, K., Moussis, V., Tsirakis, V., Trypou, P., Egot, M., Baruch, D., Kieffer, N., & Bachelot-Loza, C. (2015). Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3. PLoS ONE. doi:10.1371/journal.pone.0134952 Peer Reviewed verified by ORBi |
 | Al Tanoury, Z., Schaffner-Reckinger, E., Halavatyi, A., Hoffmann, C., Moes, M., Hadzic, E., Catillon, M., Yatskou, M., & Friederich, E. (2010). Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over. PLoS ONE, 5 (2), 9210. doi:10.1371/journal.pone.0009210 Peer Reviewed verified by ORBi |
 | Janji, B., Vallar, L., Al Tanoury, Z., Bernardin, F., Vetter, G., Schaffner-Reckinger, E., Berchem, G., Friederich, E., & Chouaib, S. (2010). The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner. Journal of Cellular and Molecular Medicine, 14 (6A), 1264-75. doi:10.1111/j.1582-4934.2009.00918.x Peer Reviewed verified by ORBi |
 | Schaffner-Reckinger, E., Salsmann, A., Debili, N., Bellis, J., De Mey, J., Vainchenker, W., Ouwehand, W. H., & Kieffer, N. (2009). Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells. Journal of Thrombosis and Haemostasis, 7 (7), 1207-1217. doi:10.1111/j.1538-7836.2009.03494.x Peer Reviewed verified by ORBi |
 | Ghevaert, C., Salsmann, A., Watkins, N. A., Schaffner-Reckinger, E., Rankin, A., Garner, S. F., Stephens, J., Smith, G. A., Debili, N., Vainchenker, W., de Groot, P. G., Huntington, J. A., Laffan, M., Kieffer, N., & Ouwehand, W. H. (2008). A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia. Blood, 111 (7), 3407-3414. doi:10.1182/blood-2007-09-112615 Peer Reviewed verified by ORBi |
 | Rodius, S., Chaloin, O., Moes, M., Schaffner-Reckinger, E., Landrieu, I., Lippens, G., Lin, M., Zhang, J., & Kieffer, N. (2008). The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges. The Journal of biological chemistry, 283 (35), 24212-23. doi:10.1074/jbc.M709704200 Peer reviewed |
Salsmann, A., Schaffner-Reckinger, E., & Kieffer, N. (2006). RGD, the Rho'd to cell spreading. European Journal of Cell Biology, 85 (3-4), 249-254. doi:10.1016/j.ejcb.2005.08.003 Peer reviewed |
Salsmann, A., Schaffner-Reckinger, E., Kabile, F., Plançon, S., & Kieffer, N. (2005). A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading. Journal of Biological Chemistry, 280 (39), 33610-33619. doi:10.1074/jbc.M500146200 Peer Reviewed verified by ORBi |
 | Joutsi-Korhonen, L., Preston, S., Smethurst, P. A., Ijsseldijk, M., Schaffner-Reckinger, E., Armour, K. L., Watkins, N. A., Clark, M. R., de Groot, P. G., Farndale, R. W., Ouwehand, W. H., & Williamson, L. M. (2004). The effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function. Thrombosis and haemostasis, 91 (4), 743-54. doi:10.1160/TH03-07-0484 Peer reviewed |
 | Schaffner-Reckinger, E. (2003). Beta3 integrins: major therapeutic targets of the near future. Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg, (1), 23-34. Peer Reviewed verified by ORBi |
 | Watkins, N. A., Schaffner-Reckinger, E., Allen, D. L., Howkins, G. J., Brons, N. H. C., Smith, G. A., Metcalfe, P., Murphy, M. F., Kieffer, N., & Ouwehand, W. H. (2002). HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope. Blood, 99 (5), 1833-9. doi:10.1182/blood.V99.5.1833 Peer reviewed |
 | Plançon, S., Morel-Kopp, M. C., Schaffner-Reckinger, E., Chen, P., & Kieffer, N. (2001). Green fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand binding. The Biochemical journal, 357 (Pt 2), 529-36. doi:10.1042/0264-6021:3570529 Peer reviewed |
 | Schaffner-Reckinger, E., Brons, N. H., & Kieffer, N. (2001). Evidence from site-directed mutagenesis that the cytoplasmic domain of the beta3 subunit influences the conformational state of the alphaVbeta3 integrin ectodomain. Thrombosis and haemostasis, 85 (4), 716-23. doi:10.1055/s-0037-1615658 Peer reviewed |
 | Schaffner-Reckinger, E., Gouon, V., Melchior, C., Plançon, S., & Kieffer, N. (1998). Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling. The Journal of biological chemistry, 273 (20), 12623-32. doi:10.1074/jbc.273.20.12623 Peer reviewed |