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KIEFFER Nelly

Main Referenced Co-authors
SCHAFFNER, Elisabeth  (6)
SALSMANN, Alexandre  (4)
Ouwehand, Willem H. (3)
Debili, Najet (2)
MOES, Michèle  (2)
Main Referenced Keywords
Animals (3); CHO Cells (3); Cricetinae (3); Humans (3); Cricetulus (2);
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (7)
Hematology (1)

Publications (total 8)

The most downloaded
162 downloads
Ghevaert, C., Salsmann, A., Watkins, N. A., Schaffner-Reckinger, E., Rankin, A., Garner, S. F., Stephens, J., Smith, G. A., Debili, N., Vainchenker, W., de Groot, P. G., Huntington, J. A., Laffan, M., Kieffer, N., & Ouwehand, W. H. (2008). A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia. Blood, 111 (7), 3407-3414. doi:10.1182/blood-2007-09-112615 https://hdl.handle.net/10993/13532

The most cited

85 citations (Scopus®)

Ghevaert, C., Salsmann, A., Watkins, N. A., Schaffner-Reckinger, E., Rankin, A., Garner, S. F., Stephens, J., Smith, G. A., Debili, N., Vainchenker, W., de Groot, P. G., Huntington, J. A., Laffan, M., Kieffer, N., & Ouwehand, W. H. (2008). A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia. Blood, 111 (7), 3407-3414. doi:10.1182/blood-2007-09-112615 https://hdl.handle.net/10993/13532

Schaffner-Reckinger, E., Salsmann, A., Debili, N., Bellis, J., De Mey, J., Vainchenker, W., Ouwehand, W. H., & Kieffer, N. (2009). Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells. Journal of Thrombosis and Haemostasis, 7 (7), 1207-1217. doi:10.1111/j.1538-7836.2009.03494.x
Peer Reviewed verified by ORBi

Ghevaert, C., Salsmann, A., Watkins, N. A., Schaffner-Reckinger, E., Rankin, A., Garner, S. F., Stephens, J., Smith, G. A., Debili, N., Vainchenker, W., de Groot, P. G., Huntington, J. A., Laffan, M., Kieffer, N., & Ouwehand, W. H. (2008). A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia. Blood, 111 (7), 3407-3414. doi:10.1182/blood-2007-09-112615
Peer Reviewed verified by ORBi

Rodius, S., Chaloin, O., Moes, M., Schaffner-Reckinger, E., Landrieu, I., Lippens, G., Lin, M., Zhang, J., & Kieffer, N. (2008). The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges. The Journal of biological chemistry, 283 (35), 24212-23. doi:10.1074/jbc.M709704200
Peer reviewed

Moes, M., Rodius, S., Coleman, S. J., Monkley, S. J., Goormaghtigh, E., Tremuth, L., Kox, C., van der Holst, P. P. G., Critchley, D. R., & Kieffer, N. (2007). The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton. The Journal of biological chemistry, 282 (23), 17280-8. doi:10.1074/jbc.M611846200
Peer reviewed

Salsmann, A., Schaffner-Reckinger, E., & Kieffer, N. (2006). RGD, the Rho'd to cell spreading. European Journal of Cell Biology, 85 (3-4), 249-254. doi:10.1016/j.ejcb.2005.08.003
Peer reviewed

Salsmann, A., Schaffner-Reckinger, E., Kabile, F., Plançon, S., & Kieffer, N. (2005). A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading. Journal of Biological Chemistry, 280 (39), 33610-33619. doi:10.1074/jbc.M500146200
Peer Reviewed verified by ORBi

Tremuth, L. A., Kreis, S., Melchior, C., Hoebeke, J., Rondé, P., Plançon, S., Takeda, K., & Kieffer, N. (2004). A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain. Journal of Biological Chemistry, 279 (21), 22258-22266. doi:10.1074/jbc.M400947200
Peer Reviewed verified by ORBi

Watkins, N. A., Schaffner-Reckinger, E., Allen, D. L., Howkins, G. J., Brons, N. H. C., Smith, G. A., Metcalfe, P., Murphy, M. F., Kieffer, N., & Ouwehand, W. H. (2002). HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope. Blood, 99 (5), 1833-9. doi:10.1182/blood.V99.5.1833
Peer reviewed

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