Profil

LUCUMI MORENO Edinson

Main Referenced Co-authors
FLEMING, Ronan MT  (4)
SCHWAMBORN, Jens Christian  (4)
Fidock, David A. (3)
HACHI, Siham  (3)
JARAZO, Javier  (3)
Main Referenced Keywords
Animals (5); Crystallography, X-Ray (3); Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/antagonists & inhibitors (3); Antimalarials/chemistry/pharmacology (2); Drug Evaluation, Preclinical (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Systems Biochemistry (Fleming Group) (3)
Luxembourg Centre for Systems Biomedicine (LCSB): Developmental and Cellular Biology (Schwamborn Group) (1)
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (7)
Biotechnology (2)
Life sciences: Multidisciplinary, general & others (2)
Microbiology (1)

Publications (total 12)

The most downloaded
611 downloads
Halldórsson, S.* , Lucumi Moreno, E.* , Gómez-Sjöberg, R., & Fleming, R. M. (15 January 2015). Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices. Biosensors and Bioelectronics, 63, 218-231. doi:10.1016/j.bios.2014.07.029 https://hdl.handle.net/10993/21149

The most cited

731 citations (Scopus®)

Halldórsson, S.* , Lucumi Moreno, E.* , Gómez-Sjöberg, R., & Fleming, R. M. (15 January 2015). Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices. Biosensors and Bioelectronics, 63, 218-231. doi:10.1016/j.bios.2014.07.029 https://hdl.handle.net/10993/21149

Bolognin, S., Fossépré, M., Qing, X., Jarazo, J., Ščančar, J., Lucumi Moreno, E., Nickels, S., Wasner, K., Ouzren, N., Walter, J., Grünewald, A., Glaab, E., Salamanca, L., Fleming, R. M. T., Antony, P., & Schwamborn, J. C. (2018). 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Advanced Science. doi:10.1002/advs.201800927
Peer Reviewed verified by ORBi

Monzel, A. S., Smits, L., Hemmer, K., Hachi, S., Lucumi Moreno, E., Van Wüllen, T. M., Jarazo, J., Walter, J., Werthschulte, I., Boussaad, I., Berger, E., Fleming, R. M., Bolognin, S., & Schwamborn, J. C. (2017). Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. doi:10.1016/j.stemcr.2017.03.010
Peer Reviewed verified by ORBi

Kane, K., Lucumi Moreno, E., Hachi, S., Walter, M., Jarazo, J., Hankemeier, T., Vulto, P., Schwamborn, J. C., Thoma, M., & Fleming, R. M. (2017). Automated micro uidic cell culture of stem cell derived dopaminergic neurons in Parkinson's disease. bioRxiv. doi:10.1038/s41598-018-34828-3

Lucumi-Moreno, E. (2016). THREE-DIMENSIONAL MICROFLUIDIC CELL CULTURE OF STEM CELL-DERIVED NEURONAL MODELS OF PARKINSON'S DISEASE [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/30115

Halldórsson, S.* , Lucumi Moreno, E.* , Gómez-Sjöberg, R., & Fleming, R. M. (15 January 2015). Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices. Biosensors and Bioelectronics, 63, 218-231. doi:10.1016/j.bios.2014.07.029
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Lucumi Moreno, E., Hachi, S., Hemmer, K., Trietsch, S., Baumuratov, A., Hankemeier, T., Vulto, P., Schwamborn, J. C., & Fleming, R. M. (2015). Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture. Lab on a Chip - Miniaturisation for Chemistry and Biology, 15, 2419-2428. doi:10.1039/C5LC00180C
Peer reviewed

Lucumi Moreno, E., Darling, C., Jo, H., Napper, A. D., Chandramohanadas, R., Fisher, N., Shone, A. E., Jing, H., Ward, S. A., Biagini, G. A., DeGrado, W. F., Diamond, S. L., & Greenbaum, D. C. (2010). Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. Antimicrobial Agents and Chemotherapy, 54 (9), 3597-604. doi:10.1128/AAC.00431-10
Peer Reviewed verified by ORBi

Clifton, J. D., Lucumi Moreno, E., Myers, M. C., Napper, A., Hama, K., Farber, S. A., Smith, A. B. R., Huryn, D. M., Diamond, S. L., & Pack, M. (2010). Identification of novel inhibitors of dietary lipid absorption using zebrafish. PLoS ONE, 5 (8), 12386. doi:10.1371/journal.pone.0012386
Peer Reviewed verified by ORBi

Nicola, G., Smith, C. A., Lucumi Moreno, E., Kuo, M. R., Karagyozov, L., Fidock, D. A., Sacchettini, J. C., & Abagyan, R. (2007). Discovery of novel inhibitors targeting enoyl-acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening. Biochemical and biophysical research communications, 358 (3), 686-91. doi:10.1016/j.bbrc.2007.04.113
Peer reviewed

Jezequel-Sur, S., Murray, J., Lucumi Moreno, E., Ferrer, M., & Zuck, P. (2007). Mixing two differently labeled substrates in one immobilized metal assay for phosphochemicals assay to improve data quality. Analytical biochemistry, 360 (2), 312-4. doi:10.1016/j.ab.2006.10.024
Peer reviewed

Freundlich, J. S., Yu, M., Lucumi Moreno, E., Kuo, M., Tsai, H.-C., Valderramos, J.-C., Karagyozov, L., Jacobs, W. R. J., Schiehser, G. A., Fidock, D. A., Jacobus, D. P., & Sacchettini, J. C. (2006). Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan derivatives. Bioorganic & Medicinal Chemistry Letters, 16 (8), 2163-9. doi:10.1016/j.bmcl.2006.01.051
Peer reviewed

Freundlich, J. S., Anderson, J. W., Sarantakis, D., Shieh, H.-M., Yu, M., Valderramos, J.-C., Lucumi Moreno, E., Kuo, M., Jacobs, W. R. J., Fidock, D. A., Schiehser, G. A., Jacobus, D. P., & Sacchettini, J. C. (2005). Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives. Bioorganic & Medicinal Chemistry Letters, 15 (23), 5247-52. doi:10.1016/j.bmcl.2005.08.044
Peer reviewed

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