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BECKER-KETTERN Julia

Main Referenced Co-authors
LINSTER, Carole  (5)
PACZIA, Nicole  (4)
CONROTTE, Jean-François  (3)
Christodoulou, John (2)
JUNG, Paul  (2)
Main Referenced Keywords
dehydrogenase (2); Inborn errors of metabolism (2); metabolite repair (2); transhydrogenase (2); 2-Hydroxyglutarate (1);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Enzymology & Metabolism (Linster Group) (3)
Luxembourg Centre for Systems Biomedicine (LCSB) (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (5)
Neurology (1)
Human health sciences: Multidisciplinary, general & others (1)

Publications (total 6)

The most downloaded
166 downloads
Van Bergen, N.* , Guo, Y.* , Rankin, J.* , PACZIA, N.* , BECKER-KETTERN, J.* , Kremer, L., Pyle, A., CONROTTE, J.-F., Ellaway, C., Procopis, P., Prelog, K., Homfray, T., Baptista, J., Baple, E., Wakeling, M., Massey, S., KAY, D., Shukla, A., Girisha, K., ... Hakonarson, H. (01 January 2019). NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses. Brain: a Journal of Neurology, 142 (1), 50-58. doi:10.1093/brain/awy310 https://hdl.handle.net/10993/37920

The most cited

83 citations (OpenAlex)

BECKER-KETTERN, J., PACZIA, N., Conrotte, J.-F., KAY, D., Guignard, C., JUNG, P., & LINSTER, C. (2016). Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase. The Journal of Biological Chemistry. doi:10.1074/jbc.M115.704494 https://hdl.handle.net/10993/24220

WALVEKAR, A., WARMOES, M. O., CHEUNG, D., Sikora, T., SEYEDKATOULI, N., Gomez-Giro, G., PERRONE, S., Dengler, L., Unger, F., Santos, B. F. R., GAVOTTO, F., DONG, X., BECKER-KETTERN, J., KWON, Y.-J., JÄGER, C., SCHWAMBORN, J. C., Van Bergen, N. J., Christodoulou, J., & LINSTER, C. (09 January 2025). Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cells. Cellular and Molecular Biology Letters, 30 (1), 3. doi:10.1186/s11658-024-00681-8
Peer Reviewed verified by ORBi

Van Bergen, N.* , Guo, Y.* , Rankin, J.* , PACZIA, N.* , BECKER-KETTERN, J.* , Kremer, L., Pyle, A., CONROTTE, J.-F., Ellaway, C., Procopis, P., Prelog, K., Homfray, T., Baptista, J., Baple, E., Wakeling, M., Massey, S., KAY, D., Shukla, A., Girisha, K., ... Hakonarson, H. (01 January 2019). NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses. Brain: a Journal of Neurology, 142 (1), 50-58. doi:10.1093/brain/awy310
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

PACZIA, N.* , BECKER-KETTERN, J.* , CONROTTE, J.-F., Cifuente, J. O., Guerin, M. E., & LINSTER, C. (2019). 3‑Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo L‑Serine Synthesis. Biochemistry. doi:10.1021/acs.biochem.8b00990
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

BECKER-KETTERN, J., PACZIA, N., CONROTTE, J.-F., Zhu, C., Fiehn, O., JUNG, P., Steinmetz, L., & LINSTER, C. (2018). NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells. FEBS Journal. doi:10.1111/febs.14631
Peer Reviewed verified by ORBi

BECKER-KETTERN, J. (2017). Study of Metabolite Repair in Eukaryotic Cells: Metabolic origin and fate of D-2-hydroxyglutarate in yeast and effect of NAD(P)HX repair deficiency on yeast and human cells [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/31030

BECKER-KETTERN, J., PACZIA, N., Conrotte, J.-F., KAY, D., Guignard, C., JUNG, P., & LINSTER, C. (2016). Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase. The Journal of Biological Chemistry. doi:10.1074/jbc.M115.704494
Peer reviewed

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